Morishita Hideaki 森下英晃

Researcher Number	90783499
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 教授 2025: 順天堂大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 九州大学, 医学研究院, 教授 2022 – 2023: 順天堂大学, 医学部, 准教授 2019 – 2021: 順天堂大学, 医学部, 講師 2016 – 2018: 東京大学, 大学院医学系研究科(医学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Transformative Research Areas, Section (III) / Basic Section 44010:Cell biology-related / Biological Sciences / Cell biology Except Principal Investigator Broad Section G / Biological Sciences
Keywords	Principal Investigator オートファジー / ゼブラフィッシュ / リソソーム / 液滴 / 選択的オートファジー / 細胞内分解 / リポタンパク質 / オルガネラ分解 / 水晶体 / 定量的プロテオミクス … More / 肝細胞 / 細胞質 / 選択的基質 / ユビキチン化タンパク質 / マウス / ユビキチン / 細胞内品質管理 / 恒常性維持 / 浮袋 / 小胞体 / リソソーム関連オルガネラ / ラメラ体 / 大規模オルガネラ分解 / オートファジー関連因子 / 脳神経疾患 / 細胞・組織 / CRISPR / サーファクタント / SENDA / 脳神経変性疾患 … More Except Principal Investigator オートファジー / 肝疾患 / p62 / KEAP1-NRF2 / 液ー液相分離 / リソソーム / ホスホリパーゼ / 細胞小器官 / 生体膜 / 細胞内分解 Less

選択的オートファジーによるユビキチン化タンパク質の寿命決定機構の解明Principal Investigator
- Principal Investigator
  
  森下英晃
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyushu University
A study on stress responses by co-creation of liquid-liquid phase separation and autophagy
- Principal Investigator
  
  小松雅明
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  Juntendo University
液滴を標的とする選択的オートファジーの生理機能の解明Principal Investigator
- Principal Investigator
  
  森下英晃
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kyushu University
Research on intracellular degradation focusing on membranous structures
- Principal Investigator
  
  水島昇
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Molecular Basis and Physiological Functions of Diverse Selective AutophagyPrincipal Investigator
- Principal Investigator
  
  Morishita Hideaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Juntendo University
Elucidation of novel physiological functions of autophagy-related factors using zebrafishPrincipal Investigator
- Principal Investigator
  
  Morishita Hideaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Juntendo University
  The University of Tokyo
オートファジーによる脳神経変性疾患の抑制メカニズムの解明Principal Investigator
- Principal Investigator
  
  森下英晃
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
マウスとゼブラフィッシュを用いた水晶体オルガネラ分解機構の解明Principal Investigator
- Principal Investigator
  
  森下英晃
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 肝胆膵2021
- Author(s)
  森下英晃、小松雅明
- Total Pages
  8
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-20H03213
[Book] 決定版阻害剤・活性化剤ハンドブック2019
- Author(s)
  濱祐太郎, 森下英晃, 水島昇
- Publisher
  羊土社
- ISBN
  9784758120999
- Data Source
  KAKENHI-PROJECT-18K14694
[Journal Article] p62 bodies: cytosolic zoning by phase separation2023
- Author(s)
  Kurusu Reo、Morishita Hideaki、Komatsu Masaaki
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 175 Issue: 2 Pages: 141-146
- DOI
  10.1093/jb/mvad089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-23K27134
[Journal Article] Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex2023
- Author(s)
  Kurusu Reo、Fujimoto Yuki、Morishita Hideaki、Noshiro Daisuke、Takada Shuhei、Yamano Koji、Tanaka Hideaki、Arai Ritsuko、Kageyama Shun、Funakoshi Tomoko、Komatsu-Hirota Satoko、Taka Hikari、Kazuno Saiko、Miura Yoshiki、Koike Masato、Wakai Toshifumi、Waguri Satoshi、Noda Nobuo N.、Komatsu Masaaki
- Journal Title
  
  Developmental Cell
  
  Volume: － Issue: 13 Pages: 1189-1205
- DOI
  10.1016/j.devcel.2023.04.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23841, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-22K06300, KAKENHI-PROJECT-23K05683, KAKENHI-PROJECT-23K06323, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-21H02998, KAKENHI-PROJECT-23K27134, KAKENHI-PROJECT-23K27351, KAKENHI-PROJECT-23H05327
[Journal Article] Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response2023
- Author(s)
  Ikeda Ryo、Noshiro Daisuke、Morishita Hideaki、Takada Shuhei、Kageyama Shun、Fujioka Yuko、Funakoshi Tomoko、Komatsu‐Hirota Satoko、Arai Ritsuko、Ryzhii Elena、Abe Manabu、Koga Tomoaki、Motohashi Hozumi、Nakao Mitsuyoshi、Sakimura Kenji、Horii Arata、Waguri Satoshi、Ichimura Yoshinobu、Noda Nobuo N、Komatsu Masaaki
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 14
- DOI
  10.15252/embj.2022113349
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18220, KAKENHI-PROJECT-22K06300, KAKENHI-PROJECT-23K05683, KAKENHI-PROJECT-23K06415, KAKENHI-PROJECT-20KK0185, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PLANNED-19H05707, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-23K27122, KAKENHI-PROJECT-23K27134, KAKENHI-PROJECT-23K27351, KAKENHI-PROJECT-23K27381, KAKENHI-PROJECT-23H05327
[Journal Article] Vault-phagy: a phase-separation-mediated selective autophagy of vault, a non-membranous organelle2023
- Author(s)
  Kurusu Reo、Morishita Hideaki、Komatsu Masaaki
- Journal Title
  
  Autophagy
  
  Volume: 20 Issue: 2 Pages: 441-442
- DOI
  10.1080/15548627.2023.2266996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K20044, KAKENHI-ORGANIZER-19H05705, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-23K27134
[Journal Article] Role of autophagy in liver diseases2022
- Author(s)
  Morishita H, Komatsu M.
- Journal Title
  
  Current Opinion in Physiology
  
  Volume: 30 Pages: 100594-100594
- DOI
  10.1016/j.cophys.2022.100594
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03213
[Journal Article] 肺の恒常性の維持：肺サーファクタントとオートファジー2022
- Author(s)
  森下英晃
- Journal Title
  
  呼吸器内科
  
  Volume: 42(6) Pages: 633-638
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] Regulation of ER‐derived membrane dynamics by the DedA domain‐containing proteins VMP1 and TMEM41B2022
- Author(s)
  Hama Yutaro、Morishita Hideaki、Mizushima Noboru
- Journal Title
  
  EMBO reports
  
  Volume: 23 Issue: 2 Pages: 0-0
- DOI
  10.15252/embr.202153894
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] Role of autophagy in the eye: from physiology to disease2022
- Author(s)
  Morishita Hideaki
- Journal Title
  
  Current Opinion in Physiology
  
  Volume: 30 Pages: 100592-100592
- DOI
  10.1016/j.cophys.2022.100592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04919, KAKENHI-PROJECT-20H03213
[Journal Article] Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response2022
- Author(s)
  Ikeda R, Noshiro D, Morishita H, Takada S, Kageyama S, Fujioka Y, Funakoshi T, Komatsu-Hirota S, Arai R, Ryzhii E, Abe M, Koga T, Nakao M, Sakimura K, Horii A, Waguri S, Ichimura Y, Noda NN, Komatsu M.
- Journal Title
  
  bioExiv
  
  Volume: 1 Pages: 521356-521356
- DOI
  10.1101/2022.12.21.521356
- Open Access
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] Molecular Mechanisms and Physiological Significance of Large-Scale Organelle Degradation in the Lens2022
- Author(s)
  森下英晃
- Journal Title
  
  The Journal of The Japanese Society for Cataract Research
  
  Volume: 34 Issue: 1 Pages: 11-14
- DOI
  10.14938/cataract.34-001
- ISSN
  0915-4302, 2188-613X
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] On the mechanism and role of organelle degradation in the lens2022
- Author(s)
  森下英晃
- Journal Title
  
  生化学
  
  Volume: 94 Issue: 5 Pages: 651-662
- DOI
  10.14952/SEIKAGAKU.2022.940651
- ISSN
  0037-1017
- Year and Date
  2022-10-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-22H04919
[Journal Article] A new insight into the lens: cytosolic PLAAT phospholipases degrade organelles to make the lens transparent2021
- Author(s)
  Morishita Hideaki、Eguchi Tomoya、Mizushima Noboru
- Journal Title
  
  Autophagy
  
  Volume: 17 Issue: 9 Pages: 2645-2647
- DOI
  10.1080/15548627.2021.1950372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] 水晶体の透明化に必要な大規模細胞小器官分解を担う新規分解機構の発見2021
- Author(s)
  森下英晃, 江口智也, 水島昇
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 2113-2116
- Data Source
  KAKENHI-PROJECT-20H03213
[Journal Article] Organelle degradation in the lens by PLAAT phospholipases2021
- Author(s)
  Morishita Hideaki、Eguchi Tomoya、Tsukamoto Satoshi、Sakamaki Yuriko、Takahashi Satoru、Saito Chieko、Koyama-Honda Ikuko、Mizushima Noboru
- Journal Title
  
  Nature
  
  Volume: 592 Issue: 7855 Pages: 634-638
- DOI
  10.1038/s41586-021-03439-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16118, KAKENHI-PROJECT-20H03213
[Journal Article] オートファジー関連因子の非オートファジー機能2020
- Author(s)
  森下英晃
- Journal Title
  
  医学のあゆみ
  
  Volume: 272 Pages: 737-744
- Data Source
  KAKENHI-PROJECT-18K14694
[Journal Article] A critical role of VMP1 in lipoprotein secretion2019
- Author(s)
  Morishita Hideaki、Zhao Yan G、Tamura Norito、Nishimura Taki、Kanda Yuki、Sakamaki Yuriko、Okazaki Mitsuyo、Li Dongfang、Mizushima Noboru
- Journal Title
  
  eLife
  
  Volume: 8 Pages: 1-24
- DOI
  10.7554/elife.48834
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19J01972, KAKENHI-PROJECT-18K14694
[Journal Article] Diverse Cellular Roles of Autophagy2019
- Author(s)
  Morishita Hideaki、Mizushima Noboru
- Journal Title
  
  Annual Review of Cell and Developmental Biology
  
  Volume: 35 Issue: 1 Pages: 453-475
- DOI
  10.1146/annurev-cellbio-100818-125300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14694
[Journal Article] Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation2018
- Author(s)
  Morita Keigo、Hama Yutaro、Izume Tamaki、Tamura Norito、Ueno Toshihide、Yamashita Yoshihiro、Sakamaki Yuriko、Mimura Kaito、Morishita Hideaki、Shihoya Wataru、Nureki Osamu、Mano Hiroyuki、Mizushima Noboru
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 217 Issue: 11 Pages: 3817-3828
- DOI
  10.1083/jcb.201804132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-18K14694, KAKENHI-PUBLICLY-17H05690, KAKENHI-PROJECT-18J20411
[Journal Article] 哺乳動物におけるオートファジーの生理機能2017
- Author(s)
  森下英晃、水島昇
- Journal Title
  
  実験医学増刊
  
  Volume: 35 Pages: 2580-2593
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Journal Article] A new probe to measure autophagic flux in vitro and in vivo.2017
- Author(s)
  Morishita H, Kaizuka T, Hama Y, Mizushima N.
- Journal Title
  
  Autophagy
  
  Volume: 13 Issue: 4 Pages: 757-758
- DOI
  10.1080/15548627.2016.1278094
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06730, KAKENHI-PROJECT-16J04376, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111005
[Journal Article] オートファジー関連神経変性の分子基盤とモデル動物2017
- Author(s)
  森下英晃、水島昇
- Journal Title
  
  最新医学
  
  Volume: 72 Pages: 184-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06730
[Journal Article] オートファジーと老化2016
- Author(s)
  森下英晃、水島昇
- Journal Title
  
  日本臨牀
  
  Volume: 74 Pages: 1461-1466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06730
[Journal Article] An Autophagic Flux Probe that Releases an Internal Control2016
- Author(s)
  Kaizuka T, Morishita H, Hama Y, Tsukamoto S, Matsui T, Toyota Y, Kodama A, Ishihara T, Mizushima T, Mizushima N*
- Journal Title
  
  Molecular Cell
  
  Volume: 17 Issue: 4 Pages: 835-849
- DOI
  10.1016/j.molcel.2016.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05637, KAKENHI-PROJECT-16H06730, KAKENHI-PROJECT-16J04376, KAKENHI-PROJECT-14J02578, KAKENHI-PLANNED-25111005
[Presentation] 新たな細胞内選択的分解機構の発見2023
- Author(s)
  森下英晃
- Organizer
  昭和大学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] A mouse model with systemic expression of an autophagic flux reporter reveals differences in basal autophagic flux among tissues and autophagy suppression in obesity and aging2023
- Author(s)
  Yuki Kanda, Tomoya Eguchi, Hideaki Morishita, Yutaro Hama, Manabu Abe, Kenji Sakimura, Noboru Mizushima
- Organizer
  Keystone Symposium: Autophagy and Neurodegeneration: Mechanisms to Therapies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] Reversibility of neurological dysfunctions caused by autophagy deficiency2023
- Author(s)
  Tomoya Eguchi, Hideaki Morishita, Manabu Abe, Kenji Sakimura, Kenji F. Tanaka, Noboru Mizushima
- Organizer
  Keystone Symposium: Autophagy and Neurodegeneration: Mechanisms to Therapies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] 液―液相分離で形成される”p62 body”の新規構成成分の同定とその選択的オートファジーによる分解意義の解明2023
- Author(s)
  森下英晃
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] 相分離p62 bodyのオートファジー分解を制御するE3リガーゼの同定2023
- Author(s)
  高田周平, 船越智子, 森下英晃, 小松雅明
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] 新たな細胞内選択的分解機構の発見2023
- Author(s)
  森下英晃
- Organizer
  第11回Cancer Stem Cell Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] 選択的オートファジーによるp62液滴分解の新規制御因子の同定2023
- Author(s)
  高田周平, 船越智子, 森下英晃, 小松雅明
- Organizer
  第75回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] PP2A複合体による脱リン酸化を介したp62 bodyの脱制御2023
- Author(s)
  李佳晨, 森下英晃, 小松(廣田) 聡子, 和栗聡, 一村義信, 小松雅明
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K27134
[Presentation] 選択的オートファジーにより分解される新規超分子複合体の同定2022
- Author(s)
  来栖玲央, 藤本侑生, 森下英晃, 高田周平, 和栗聡, 小松雅明
- Organizer
  日本顕微鏡学会第78回学術講演会
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] 肺の恒常性オートファジーとサーファクタント2022
- Author(s)
  森下英晃
- Organizer
  日本肺サーファクタント・界面医学会第58回学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] 水晶体における全オルガネラ分解現象の分子機構と意義の解明2022
- Author(s)
  森下英晃
- Organizer
  第64回日本脂質生化学会シンポジウム「眼と脂質」
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] A novel mouse line systemically expressing an autophagic flux reporter revealed autophagy suppression in pathological conditions2022
- Author(s)
  神田侑季、江口智也、森下英晃、濱祐太郎、阿部学、崎村建司、水島昇
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] Proteomic approach of purified p62-body and selective autophagy-defective mice reveals a novel p62-mediated selective autophagy2022
- Author(s)
  Komatsu M, Kurusu R, Fujimoto Y, Morishita H
- Organizer
  EMBO Autophagy meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] A novel mouse line systemically expressing GFP-LC3-RFP reveals autophagy suppression in obesity and aging2022
- Author(s)
  Yuki Kanda, Tomoya Eguchi, Hideaki Morishita, Yutaro Hama, Manabu Abe, Kenji Sakimura, Noboru Mizushima
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] オートファジー活性レポーター発現マウスの作製と評価2022
- Author(s)
  神田侑季、江口智也、森下英晃、濱祐太郎、阿部学、崎村建司、水島昇
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] 水晶体における全オルガネラ分解現象の分子機構と意義の解明2022
- Author(s)
  森下英晃
- Organizer
  第64回日本脂質生化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] A cytosolic PLAAT phospholipase is essential for the programmed degradation of organelles in the lens2022
- Author(s)
  Hideki Morishita
- Organizer
  ARVO 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] ULK1 キナーゼによる p62 の液―液相分離制御2022
- Author(s)
  池田良, 一村義信, 森下英晃, 能代大輔, 船越智子, 小松聡子, 野田展生, 小松雅明
- Organizer
  日本Cell Death学会第30回学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] 水晶体における全オルガネラ分解現象の分子機構および生理的意義の解明2022
- Author(s)
  森下英晃、江口智也、塚本智史、高橋暁、酒巻有里子、齊藤知恵子、小山-本田郁子、水島昇
- Organizer
  日本CellDeath学会　第30回学術集会
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] Proteomic approaches to purified p62-bodies and selective autophagy-deficient mice identify a novel substrate for p62-mediated selective autophagy.2022
- Author(s)
  Morishita H, Kurusu R, Fujimoto Y, Takada S, Komatsu M
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] 肺の恒常性オートファジーとサーファクタント2022
- Author(s)
  森下英晃
- Organizer
  日本肺サーファクタント・界面医学会第58回学術研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04919
[Presentation] p62液滴精製による新規選択的オートファジー基質の同定2021
- Author(s)
  藤本侑生, 来栖玲央, 森下英晃, 小松雅明
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] 日本生化学会奨励賞受賞記念講演：水晶体における大規模細胞小器官分解の分子機構と生理的意義の解明2021
- Author(s)
  森下英晃
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] Ken-ichi Arai Award 2021受賞記念講演：Physiological roles and molecular mechanisms of autophagy-dependent and independent degradation systems in vertebrates.2021
- Author(s)
  Hideaki Morishita
- Organizer
  The 27th East Asia Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03213
[Presentation] オートファジー関連因子WDR45/WDR45Bの脳神経系細胞における機能解析2019
- Author(s)
  森下英晃、神田侑季，田村律人，水島昇
- Organizer
  新学術領域研究「脳タンパク質老化と認知症制御」第9回班員会議
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] 水晶体における新規オルガネラ膜分解機構の同定と生理的意義の解明2019
- Author(s)
  森下英晃、江口智也、塚本智史、水島昇
- Organizer
  第12回オートファジー研究会・第1回新学術領域研究「マルチモードオートファジー」班会議
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 脊椎動物におけるオートファジー関連因子群の新たな生理機能2019
- Author(s)
  森下英晃、田村律人、神田侑季、酒巻有里子、水島昇
- Organizer
  第19回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 脊椎動物におけるオートファジー関連遺伝子群の新たな生理機能2019
- Author(s)
  森下英晃、神田侑季、千野遥、酒巻有里子、貝塚剛志、水島昇
- Organizer
  第66回日本実験動物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] A novel macroautophagy-independent mechanism of organelle degradation in the lens2019
- Author(s)
  Hideaki Morishita, Tomoya Eguchi, Satoshi Tsukamoto, Noboru Mizushima
- Organizer
  The 9th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] A cytosolic phospholipase-mediated organellar degradation in the lens2019
- Author(s)
  Hideaki Morishita, Tomoya Eguchi, Noboru Mizushima
- Organizer
  International Conference on the Lens 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 水晶体オルガネラ分解の分子機構と生理的意義の解明2019
- Author(s)
  森下英晃、江口智也、塚本智史、水島昇
- Organizer
  第58回日本白内障学会総会／第45回水晶体研究会
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] Autophagy is required for formation of surfactant-containing lamellar bodies in alveolar and swimbladder epithelial cells2019
- Author(s)
  Hideaki Morishita, Yuki Kanda, Haruka Chino, Takeshi Kaizuka, Yuriko Sakamaki, Noboru Mizushima
- Organizer
  Keystone Sumposia Autophagy: FromModel Systems to Therapeutic Opportunities
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] Live imaging and molecular dissection of organelle degradation in the lens2019
- Author(s)
  Hideaki Morishita, Tomoya Eguchi, Satoshi Tsukamoto, Noboru Mizushima
- Organizer
  EMBO Workshop (Autophagy: From molecular principles to human diseases)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 水晶体における新規膜系オルガネラ分解機構の解明2019
- Author(s)
  森下英晃、江口智也、塚本智史、水島昇
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] オートファジー関連因子WDR45/WDR45Bの脳神経系細胞における機能解析2019
- Author(s)
  森下英晃、神田侑季，田村律人，水島昇
- Organizer
  新学術領域研究「脳タンパク質老化と認知症制御」第9回班員会議
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] In vivo analysis of the functions of autophagy-related factors using zebrafish2018
- Author(s)
  森下英晃、神田侑季、千野遥、酒巻有里子、貝塚剛志、水島昇
- Organizer
  A3 Conference on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] 水晶体細胞の最終分化過程におけるオルガネラ分解機構の解明2018
- Author(s)
  森下英晃、江口智也、水島昇
- Organizer
  第57 回日本白内障学会総会/第44 回水晶体研究会
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] ゼブラフィッシュを用いたオートファジー関連遺伝性神経変性疾患の病態解明2018
- Author(s)
  森下英晃、水島昇
- Organizer
  第1回国際シンポジウム「モデル生物を用いた希少、未診断疾患へのアプローチ」
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] 新規オートファジー活性可視化マウスの開発2018
- Author(s)
  森下英晃
- Organizer
  第３回可視化マウス研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] オートファジー関連因子群による脳神経変性疾患抑制機構の解明2018
- Author(s)
  森下英晃、水島昇
- Organizer
  新学術領域研究脳タンパク質老化と認知症制御第7回班員会議
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] 小胞体膜タンパク質VMP1はリポタンパク質の小胞体からの脱離に必要である2018
- Author(s)
  森下英晃、田村律人、Yan GZhao、西村多喜、神田侑季、酒巻有里子、岡崎三代、Dongfang Li、Hong Zhang、水島昇
- Organizer
  第11回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] ゼブラフィッシュを用いたオートファジー関連因子群の胚発生期における生理機能の解明2018
- Author(s)
  森下英晃
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] オートファジー関連因子WDR45に変異を伴う脳神経変性疾患SENDAの病態解明2018
- Author(s)
  森下英晃，神田侑季，田村律人，清水宏，村松一洋，柿田明美，水島昇
- Organizer
  新学術領域研究「脳タンパク質老化と認知症制御」第8回班員会議
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] オートファジー関連因子WDR45に変異を伴う脳神経変性疾患SENDAの病態解明2018
- Author(s)
  森下英晃，神田侑季，田村律人，清水宏，村松一洋，柿田明美，水島昇
- Organizer
  新学術領域研究「脳タンパク質老化と認知症制御」第8回班員会議
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] オートファジーの分子メカニズムと疾患モデル動物開発2018
- Author(s)
  森下英晃
- Organizer
  第60回日本小児神経学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] オートファジーの分子メカニズムと疾患モデル動物開発2018
- Author(s)
  森下英晃
- Organizer
  第60回日本小児神経学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] オートファジーの生理機能とヒト遺伝性疾患との関連2018
- Author(s)
  森下英晃
- Organizer
  第12回生態影響試験実習セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 脊椎動物におけるオートファジー関連因子群の新たな生理機能2018
- Author(s)
  森下英晃、田村律人、神田侑季、千野遥、江口智也、西村多喜、酒巻有里子、貝塚剛志、岡崎三代、山本林、水島昇
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K14694
[Presentation] 水晶体オルガネラ分解のライブイメージングと分子機構の解明2017
- Author(s)
  森下英晃
- Organizer
  第11回炎症・脂質代謝・メタボリサーチフォーラム
- Place of Presentation
  東京大学山上会館
- Year and Date
  2017-03-04
- Data Source
  KAKENHI-PROJECT-16H06730
[Presentation] オートファジーの活性を簡便かつ定量的に測定可能な新規プローブの開発2017
- Author(s)
  森下英晃
- Organizer
  CBI学会2017年大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] Dissection of the mechanisms by which autophagy suppresses neurodegeneration using zebrafish as a model2017
- Author(s)
  森下英晃、水島昇
- Organizer
  2nd Internatinal Symposium of “Brain Protein Aging and Dementia Control”
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] ゼブラフィッシュを用いたオートファジー関連遺伝子群のin vivo機能解析2017
- Author(s)
  森下英晃
- Organizer
  日本学術振興会日中韓フォーサイト事業A3日本オートファジー合同セミナー
- Place of Presentation
  ザ・セレクトン福島
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-16H06730
[Presentation] ゼブラフィッシュを用いたオートファジー関連因子群のin vivo機能解析2017
- Author(s)
  森下英晃、水島昇
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] オートファジーによる脳神経変性疾患抑制メカニズムの解明2017
- Author(s)
  森下英晃、水島昇
- Organizer
  新学術領域研究脳タンパク質老化と認知症制御第6回班員会議
- Data Source
  KAKENHI-PUBLICLY-17H05690
[Presentation] 水晶体における新規オルガネラ分解システムのライブイメージングと分子機構の解明2016
- Author(s)
  森下英晃
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16H06730

1. 水島昇 (10353434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 小嶋良輔 (10808059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 塚本智史 (80510693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 小松雅明 (90356254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 野田展生 (40396297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 和栗聡 (30244908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三浦芳樹 (90279240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 山野晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 江口智也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morishita Hideaki 森下 英晃

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選択的オートファジーによるユビキチン化タンパク質の寿命決定機構の解明Principal Investigator

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A study on stress responses by co-creation of liquid-liquid phase separation and autophagy

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液滴を標的とする選択的オートファジーの生理機能の解明Principal Investigator

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Research on intracellular degradation focusing on membranous structures

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Molecular Basis and Physiological Functions of Diverse Selective AutophagyPrincipal Investigator

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Elucidation of novel physiological functions of autophagy-related factors using zebrafishPrincipal Investigator

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オートファジーによる脳神経変性疾患の抑制メカニズムの解明Principal Investigator

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マウスとゼブラフィッシュを用いた水晶体オルガネラ分解機構の解明Principal Investigator

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[Book] 肝胆膵2021

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[Book] 決定版 阻害剤・活性化剤ハンドブック2019

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[Journal Article] p62 bodies: cytosolic zoning by phase separation2023

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[Journal Article] Integrated proteomics identifies p62-dependent selective autophagy of the supramolecular vault complex2023

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[Journal Article] Phosphorylation of phase‐separated p62 bodies by ULK1 activates a redox‐independent stress response2023

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[Journal Article] Vault-phagy: a phase-separation-mediated selective autophagy of vault, a non-membranous organelle2023

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Morishita Hideaki 森下英晃

[Book] 決定版阻害剤・活性化剤ハンドブック2019