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Tsumura Ryo  津村 遼

ORCIDConnect your ORCID iD *help
Researcher Number 90785586
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員
Affiliation (based on the past Project Information) *help 2024 – 2025: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員
2021: 国立研究開発法人国立がん研究センター, 先端医療開発センター・新薬開発分野, 研究員
2018 – 2020: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 47040:Pharmacology-related
Except Principal Investigator
Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords
Principal Investigator
抗体抗がん剤複合体 / 組織因子 / 抗体 / 性状解析 / 結合速度定数 / 性状評価 / 結合カイネティクス / 抗体改変技術 / 膵臓がん / マウス膵がん細胞株 … More / 遺伝子改変マウス / Linker / 組織因子(TF) / 抗体抗がん剤複合体(ADC) / DDS / ドラッグデリバリー / 腫瘍間質 … More
Except Principal Investigator
二重特異性抗体 / 骨転移 / 前立腺癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (5 People)
  •  腫瘍微小環境が起因するT細胞依存性二重特異性抗体への治療抵抗性機序の解明Principal Investigator

    • Principal Investigator
      津村 遼
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      National Cancer Center Japan
  •  Establishing a foundation for T-cell immunotherapy using bispecific antibodies for bone metastatic prostate cancer.

    • Principal Investigator
      稲田 全規
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Relationship between association rate constant and characteristics of antibody-drug conjugatePrincipal Investigator

    • Principal Investigator
      Tsumura Ryo
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      National Cancer Center Japan
  •  Feasibility study of antibody-drug conjugates against tissue factorPrincipal Investigator

    • Principal Investigator
      Tsumura Ryo
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      National Cancer Center Japan

All 2020 2019 2018

All Journal Article Presentation Book

  • [Book] Cancer Drug Delivery Systems Based on the Tumor Microenvironment.2019

    • Author(s)
      Matsumura Yasuhiro, Tarin David, et al.
    • Total Pages
      325
    • Publisher
      Springer Japan
    • ISBN
      9784431568803
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Journal Article] Antitumor effect of humanized anti-tissue factor antibody-drug conjugate in a model of peritoneal disseminated pancreatic cancer2020

    • Author(s)
      Tsumura Ryo、Anzai Takahiro、Manabe Shino、Takashima Hiroki、Koga Yoshikatsu、Yasunaga Masahiro、Matsumura Yasuhiro
    • Journal Title

      Oncology Reports

      Volume: 45 Issue: 1 Pages: 329-336

    • DOI

      10.3892/or.2020.7850

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16021
  • [Journal Article] Evaluation of the antitumor mechanism of antibody‐drug conjugates against tissue factor in stroma‐rich allograft models2019

    • Author(s)
      Tsumura Ryo、Manabe Shino、Takashima Hiroki、Koga Yoshikatsu、Yasunaga Masahiro、Matsumura Yasuhiro
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 10 Pages: 3296-3305

    • DOI

      10.1111/cas.14146

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15297, KAKENHI-PROJECT-18K14931
  • [Presentation] 抗組織因子(Tissue factor)抗体を用いたADCの研究開発2020

    • Author(s)
      津村遼
    • Organizer
      理研シンポジウム. エンジニアリングネットワーク・ワークショップ. 第二回精密武装抗体の合成と機能評価
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Presentation] Development of humanized anti-tissue factor antibody-drug conjugates for pancreatic cancer treatment2019

    • Author(s)
      Ryo Tsumura, Takahiro Anzai, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Presentation] ヒト化抗tissue factor抗体を用いた抗体抗がん剤複合体の有用性評価2019

    • Author(s)
      津村遼, 安西高廣, 眞鍋史乃, 髙島大輝, 古賀宣勝, 安永正浩, 松村保広
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Presentation] Dual targeting of antibody-drug conjugates against mouse tissue factor in vivo2018

    • Author(s)
      Ryo Tsumura, Shino Manabe, Hiroki Takashima, Yoshikatsu Koga, Masahiro Yasunaga, Yasuhiro Matsumura
    • Organizer
      9th World ADC San Diego
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Presentation] The in vivo study of antibody-drug conjugates against mouse tissue factor2018

    • Author(s)
      津村遼、眞鍋史乃、髙島大輝、古賀宣勝、安永正浩、松村保広
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K14931
  • [Presentation] 組織因子を標的とした抗体抗がん剤複合体の膵がん同所移植モデルにおける治療評価2018

    • Author(s)
      津村遼、眞鍋史乃、髙島大輝、古賀宣勝、安永正浩、松村保広
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K14931
  • 1.  稲田 全規 (80401454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  平田 美智子 (40544060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  浅野 竜太郎 (80323103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  三浦 大明 (80982644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  高島 大輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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