Nakamura Jun 中村純

Researcher Number	90804518
Other IDs	https://orcid.org/0000-0002-1756-7199
Affiliation (Current)	2024: 大阪公立大学, 大学院獣医学研究科 , 客員研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪公立大学, 大学院獣医学研究科, 客員研究員 2020 – 2021: 大阪府立大学, 生命環境科学研究科, 客員研究員 2017 – 2018: 大阪府立大学, 生命環境科学研究科, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Metabolomics Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator ホルムアルデヒド / 付加体 / M2FA / ADH5 / ALDH2 / マロンジアルデヒド / 質量解析 / 鎖間架橋 / DNA蛋白クロスリンク / グリシドアルデヒド … More / DNA鎖間架橋 / グリシドール / アルデヒド / 循環器・高血圧 / ApoEノックアウトマウス / ApoE欠損マウス / 粥状動脈硬化 / リジン付加体 / 動脈硬化 / 酸化ストレス … More Except Principal Investigator 神経発達障害 / メタボリック症候群 / 子癇前症 / fetal growth restriction / 5/6腎臓摘出母体 Less

5/6腎臓摘出母体から生まれた子の成長に関する研究：新たな子癇前症モデルの開発
- Principal Investigator
  
  岡田利也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osaka Metropolitan University
Diseases caused by the accumulation of endogenous formaldehydePrincipal Investigator
- Principal Investigator
  
  中村純
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Formaldehyde induces superbulky DNA interstrand crosslinksPrincipal Investigator
- Principal Investigator
  
  中村純
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Immune response to lysine adducts in atherogenesisPrincipal Investigator
- Principal Investigator
  
  Nakamura Jun
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Osaka Prefecture University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] An unexpected butadiene diolepoxide-mediated genotoxicity implies alternative mechanism for 1,3-butadiene carcinogenicity2021
- Author(s)
  Nakamura Jun、Carro Sujey、Gold Avram、Zhang Zhenfa
- Journal Title
  
  Chemosphere
  
  Volume: 266 Pages: 129149-129149
- DOI
  10.1016/j.chemosphere.2020.129149
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Journal Article] Potential Doxorubicin-Mediated Dual-Targeting Chemotherapy in FANC/BRCA-Deficient Tumors via Modulation of Cellular Formaldehyde Concentration2020
- Author(s)
  Nakamura Jun
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: 33 Issue: 10 Pages: 2659-2667
- DOI
  10.1021/acs.chemrestox.0c00288
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Journal Article] The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice2020
- Author(s)
  Nakamura Jun、Holley Darcy W.、Kawamoto Toshihiro、Bultman Scott J.
- Journal Title
  
  Genes and Environment
  
  Volume: 42 Issue: 1 Pages: 21-21
- DOI
  10.1186/s41021-020-00160-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Journal Article] DNA-protein crosslink formation by endogenous aldehydes and AP sites2020
- Author(s)
  Nakamura Jun、Nakamura Mai
- Journal Title
  
  DNA Repair
  
  Volume: 88 Pages: 102806-102806
- DOI
  10.1016/j.dnarep.2020.102806
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Journal Article] New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis2020
- Author(s)
  Tian Shaomin、Nakamura Jun、Hiller Sylvia、Simington Stephen、Holley Darcy W.、Mota Roberto、Willis Monte S.、Bultman Scott J.、Luft J. Christopher、DeSimone Joseph M.、Jia Zhenquan、Maeda Nobuyo、Yi Xianwen
- Journal Title
  
  Vascular Pharmacology
  
  Volume: 133-134 Pages: 106777-106777
- DOI
  10.1016/j.vph.2020.106777
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] アルコールデヒドロゲナーゼとGlycidolから生成される反応代謝物のDNA架橋形成能評価2022
- Author(s)
  藤田優也, 中村純, Zhang Zhenfa, 松田知成, 川西優喜
- Organizer
  日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] アルコールデヒドロゲナーゼ(ADH)と Glycidol の反応代謝物による新規 DNA 鎖間架橋形成経路に関する研究2022
- Author(s)
  藤田優也、中村純、Zhenfa Zhang、松田智成、高田穣、川西優喜
- Organizer
  変異機構研究会・第33回夏の学校
- Data Source
  KAKENHI-PROJECT-21H03603
[Presentation] 電子タバコのべーパーなどに含まれるグリシドールが代謝活性化され DNA 鎖間架橋を誘導する2022
- Author(s)
  中村純、藤田優也、松田知成、川西優喜
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] Alcohol dehydrogenase-mediated activation of glycidol leads to the generation of DNA-crosslinking metabolites2022
- Author(s)
  Yuya Fujia, Jun Nakamura, Zhenfa Zhang, Tomonari Matuda, Masanobu Kawanisi
- Organizer
  13th International Conference on Environmental Mutagens, Ottawa, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] Alcohol dehydrogenase-mediated activation of glycidol leads to the generation of DNA-crosslinking metabolites2022
- Author(s)
  Yuya Fujia, Jun Nakamura, Zhenfa Zhang, Tomonari Matuda, Masanobu Kawanisi
- Organizer
  13th International Conference on Environmental Mutagens, Ottawa, Canada
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03603
[Presentation] アルコールデヒドロゲナーゼ(ADH)と Glycidol の反応代謝物による新規 DNA 鎖間架橋形成経路に関する研究2022
- Author(s)
  藤田優也、中村純、Zhenfa Zhang、松田智成、高田穣、川西優喜
- Organizer
  変異機構研究会・第33回夏の学校
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] アルコールデヒドロゲナーゼ(ADH)を介した新規 DNA 鎖間架橋形成経路に関する研究2022
- Author(s)
  藤田優也, 中村純, Zhang Zhenfa, 松田知成, 高田穣, 川西優喜
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-21H03603
[Presentation] アルコールデヒドロゲナーゼ(ADH)を介した新規 DNA 鎖間架橋形成経路に関する研究2022
- Author(s)
  藤田優也, 中村純, Zhang Zhenfa, 松田知成, 高田穣, 川西優喜
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] アルコールデヒドロゲナーゼとGlycidolから生成される反応代謝物のDNA架橋形成能評価2022
- Author(s)
  藤田優也, 中村純, Zhang Zhenfa, 松田知成, 川西優喜
- Organizer
  日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-21H03603
[Presentation] 電子タバコのべーパーなどに含まれるグリシドールが代謝活性化され DNA 鎖間架橋を誘導する2022
- Author(s)
  中村純、藤田優也、松田知成、川西優喜
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H03603
[Presentation] ホルムアルデヒドによるストレスがもたらす生体への影響2021
- Author(s)
  中村純
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] Unexpected 3-Butene-1,2-Diol-Mediated Genotoxicity Implies Alternative Mechanism of 1,3-Butadiene Carcinogenesis2020
- Author(s)
  Jun Nakamura, Sujey Carro, Avram Gold, Zhenfa Zhang
- Organizer
  Environmental Mutagenesis & Genomics Society Virtual Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] ホルムアルデヒド/アセトアルデヒドにより産生される蛍光性付加体と免疫反応2020
- Author(s)
  中村純
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] Antigenic, Inflammatory DHP-Lysine Adducts Are Induced by Aldehydes in the Vapor of Both Flavored and Unflavored E-cigarettes and Heated Tobacco Products2020
- Author(s)
  Jun Nakamura, Masanobu Kawanishi, Takashi Yagi, Toshiya Okada, Naoki Kunugita
- Organizer
  Society of Toxicology Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] エポキシブタンジオールの遺伝毒性の解析により明らかになったブタジエンの新たな発癌メカニズム2020
- Author(s)
  中村純, Sujey Carro, Avram Gold, Zhenfa Zhang
- Organizer
  日本環境変異原学会
- Data Source
  KAKENHI-PROJECT-20K21850
[Presentation] Blood Titers Of Antibody Against Complex Malondialdehyde-Acetaldehyde-Lysine Adducts As A Biomarker For The Very Early Stage Of Metabolic Syndromes Such As Atherosclerosis2019
- Author(s)
  Jun Nakamura
- Organizer
  58th Annual Meeting of the Society of Toxicology (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07027
[Presentation] PIG遺伝子をターゲットにした新たな遺伝子突然変異検出系の開発2018
- Author(s)
  中村純
- Organizer
  日本環境変異学会ー哺乳動物試験研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H07027

1. 川西優喜 (70332963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 岡田利也 (00169111)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 中島崇行 (30333644)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 松田知成 (50273488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 井澤武史 (20580369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 片平じゅん (30263312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 佐々木光穂 (20432536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 近藤友宏 (40585238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Nakamura Jun 中村 純

Research Projects

Research Products

Co-Researchers

5/6腎臓摘出母体から生まれた子の成長に関する研究：新たな子癇前症モデルの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diseases caused by the accumulation of endogenous formaldehydePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Formaldehyde induces superbulky DNA interstrand crosslinksPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Immune response to lysine adducts in atherogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An unexpected butadiene diolepoxide-mediated genotoxicity implies alternative mechanism for 1,3-butadiene carcinogenicity2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Doxorubicin-Mediated Dual-Targeting Chemotherapy in FANC/BRCA-Deficient Tumors via Modulation of Cellular Formaldehyde Concentration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA-protein crosslink formation by endogenous aldehydes and AP sites2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] アルコールデヒドロゲナーゼとGlycidolから生成される反応代謝物のDNA架橋形成能評価2022

Author(s)

Organizer

Data Source

[Presentation] アルコールデヒドロゲナーゼ(ADH)と Glycidol の反応代謝物による新規 DNA 鎖間架橋形成経路に関する研究2022

Author(s)

Organizer

Data Source

[Presentation] 電子タバコのべーパーなどに含まれるグリシドールが代謝活性化され DNA 鎖間架橋を誘導する2022

Author(s)

Organizer

Data Source

[Presentation] Alcohol dehydrogenase-mediated activation of glycidol leads to the generation of DNA-crosslinking metabolites2022

Author(s)

Organizer

Data Source

[Presentation] Alcohol dehydrogenase-mediated activation of glycidol leads to the generation of DNA-crosslinking metabolites2022

Author(s)

Organizer

Data Source

[Presentation] アルコールデヒドロゲナーゼ(ADH)と Glycidol の反応代謝物による新規 DNA 鎖間架橋形成経路に関する研究2022

Author(s)

Organizer

Data Source

[Presentation] アルコールデヒドロゲナーゼ(ADH)を介した新規 DNA 鎖間架橋形成経路に関する研究2022

Author(s)

Organizer

Nakamura Jun 中村純

[Presentation] エポキシブタンジオールの遺伝毒性の解析により明らかになったブタジエンの新たな発癌メカニズム2020