ONO YUSUKE 小野佑輔

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Ono Yusuke 小野佑輔

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Researcher Number	90812355
Affiliation (Current)	2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2019 – 2023: 札幌医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator CYP26A1 / 膵癌 / ビタミンA / レチノイン酸 / 膵がん / トランスクリプトーム / 舌癌 / がん悪性化 / 口腔がん / タイト結合 … More / 代謝酵素 / 線維化 / 星細胞 / レチノイン酸代謝酵素 Less

レチノイン酸特異的代謝酵素CYP26のレチノイン酸非依存性がん悪性化機構の解明Principal Investigator
- Principal Investigator
  
  小野佑輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University
Pancreatic stellate cells are activated by vitamin A deficiency, causing fibrosis and malignant transformation in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Ono Yusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Sapporo Medical University

All 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series2023
- Author(s)
  Daisuke Kyuno 1 , Masatoshi Tateno 2 , Yusuke Ono 1 , Kazufumi Magara 1 , Kumi Takasawa 1 , Akira Takasawa 1 , Makoto Osanai 1
- Journal Title
  
  Heliyon .
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983
[Journal Article] Vitamin D metabolism in cancer: potential feasibility of vitamin D metabolism blocking therapy2023
- Author(s)
  Kamiya Sakura、Nakamori Yuna、Takasawa Akira、Takasawa Kumi、Kyuno Daisuke、Ono Yusuke、Magara Kazufumi、Osanai Makoto
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 7 Issue: 2 Pages: 85-93
- DOI
  10.1007/s00795-023-00348-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K06445
[Journal Article] Retinoic acid metabolism in cancer: potential feasibility of retinoic acid metabolism blocking therapy2023
- Author(s)
  Osanai Makoto、Takasawa Akira、Takasawa Kumi、Kyuno Daisuke、Ono Yusuke、Magara Kazufumi
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 56 Issue: 1 Pages: 1-10
- DOI
  10.1007/s00795-022-00345-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K06445
[Journal Article] A novel approach to diagnosing crystal-storing histiocytosis: utility of scanning electron microscopy for formalin-fixed paraffin-embedded tissue specimens2023
- Author(s)
  Kazufumi Magara 1 , Akira Takasawa 2 , Keisuke Kikuchi 3 , Taro Sugawara 4 , Taro Murakami 1 , Daisuke Kyuno 1 , Yusuke Ono 1 , Kumi Takasawa 1 , Yasunao Numata 5 , Shigeru Sasaki 5 , Hiroshi Nakase 5 , Tadashi Hasegawa 4 , Makoto Osanai 1
- Journal Title
  
  Med Mol Morphol .
  
  Volume: 56 Issue: 4 Pages: 297-302
- DOI
  10.1007/s00795-023-00363-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] Elevated expression of endocan in the development of cervical squamous neoplasia of the uterus2023
- Author(s)
  Sato M, Inoue A, Takasawa A, Takasawa K, Kyuno D, Ono Y, Magara K, Osanai M.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 56 Issue: 3 Pages: 187-193
- DOI
  10.1007/s00795-023-00353-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] Invasive pulmonary aspergillosis with candidiasis: usefulness of molecular and ultrastructural morphological analysis on FFPE tissue for invasive fungal infections2023
- Author(s)
  Kubota Yusaku、Takasawa Akira、Ono Yusuke、Aoyama Tomoyuki、Takasawa Kumi、Tada Akinori、Magara Kazufumi、Murakami Taro、Daimon Fuminori、Yamamoto Soh、Sato Shota、Hiratsuka Yutaro、Kyuno Daisuke、Osanai Makoto
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 56 Issue: 2 Pages: 144-151
- DOI
  10.1007/s00795-023-00349-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-22K06944, KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-23K06445
[Journal Article] COVID-19-associated disseminated mucormycosis: An autopsy case report2022
- Author(s)
  Kyuno Daisuke、Kubo Terufumi、Tsujiwaki Mitsuhiro、Sugita Shintaro、Hosaka Michiko、Ito Hazuki、Harada Keisuke、Takasawa Akira、Kubota Yusaku、Takasawa Kumi、Ono Yusuke、Magara Kazufumi、Narimatsu Eichi、Hasegawa Tadashi、Osanai Makoto
- Journal Title
  
  World Journal of Clinical Cases
  
  Volume: 10 Issue: 28 Pages: 10358-10365
- DOI
  10.12998/wjcc.v10.i28.10358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06983, KAKENHI-PROJECT-20K07409
[Journal Article] Claudin-18.2 as a therapeutic target in cancers: cumulative findings from basic research and clinical trials2021
- Author(s)
  Kyuno Daisuke、Takasawa Akira、Takasawa Kumi、Ono Yusuke、Aoyama Tomoyuki、Magara Kazufumi、Nakamori Yuna、Takemasa Ichiro、Osanai Makoto
- Journal Title
  
  Tissue Barriers
  
  Volume: 10 Issue: 1 Pages: 1967080-1967080
- DOI
  10.1080/21688370.2021.1967080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-21K08715, KAKENHI-PROJECT-20K16196, KAKENHI-PROJECT-22K06983
[Journal Article] Identification of Coiled-Coil Domain-Containing Protein 180 and Leucine-Rich Repeat-Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue.2019
- Author(s)
  Aoyama T, Takasawa A, Takasawa K, Ono Y, Emori M, Murata M, Hayasaka T, Fujitani N, Osanai M, Yamashita T, Hasegawa T, Sawada N.
- Journal Title
  
  Am J Pathol.
  
  Volume: in press Issue: 5 Pages: 1015-1028
- DOI
  10.1016/j.ajpath.2019.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08698, KAKENHI-PROJECT-18K15084, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-18K09112, KAKENHI-PROJECT-19K16561, KAKENHI-PROJECT-19K16588, KAKENHI-PROJECT-17K08697, KAKENHI-PROJECT-17K10974
[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、舌癌の悪性化に関与する。2023
- Author(s)
  桑原未羽黒田睦喜小野佑輔髙澤啓及能大輔真柄和史青山智志髙澤久美小山内誠
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06983
[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、膵癌細胞の悪性形質の促進に関与する2022
- Author(s)
  井上彩乃、小野佑輔
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K16588
[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、膵癌細胞の悪性形質の促進に関与する。2022
- Author(s)
  井上彩乃小野佑輔高澤啓及能大輔真柄和史青山智志高澤久美小山内誠
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06983
[Presentation] タイト結合関連分子claudin-18は、レチノイン酸欠乏を原因とする乳がん悪性化に関与する2019
- Author(s)
  小野佑輔、小山内誠、青山智志、高澤久美、高澤啓、村田雅樹
- Organizer
  108回日本病理学会
- Data Source
  KAKENHI-PROJECT-19K16588

1. 高澤啓 (00593021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 小山内誠 (60381266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. MURATA Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 青山智志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ONO YUSUKE 小野 佑輔

Ono Yusuke 小野 佑輔

Research Projects

Research Products

Co-Researchers

レチノイン酸特異的代謝酵素CYP26のレチノイン酸非依存性がん悪性化機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pancreatic stellate cells are activated by vitamin A deficiency, causing fibrosis and malignant transformation in pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Common pathological findings in the heart in COVID-19-related sudden death cases: An autopsy case series2023

Author(s)

Journal Title

Data Source

[Journal Article] Vitamin D metabolism in cancer: potential feasibility of vitamin D metabolism blocking therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinoic acid metabolism in cancer: potential feasibility of retinoic acid metabolism blocking therapy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel approach to diagnosing crystal-storing histiocytosis: utility of scanning electron microscopy for formalin-fixed paraffin-embedded tissue specimens2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated expression of endocan in the development of cervical squamous neoplasia of the uterus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Invasive pulmonary aspergillosis with candidiasis: usefulness of molecular and ultrastructural morphological analysis on FFPE tissue for invasive fungal infections2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] COVID-19-associated disseminated mucormycosis: An autopsy case report2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Claudin-18.2 as a therapeutic target in cancers: cumulative findings from basic research and clinical trials2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Coiled-Coil Domain-Containing Protein 180 and Leucine-Rich Repeat-Containing Protein 4 as Potential Immunohistochemical Markers for Liposarcoma Based on Proteomic Analysis Using Formalin-Fixed, Paraffin-Embedded Tissue.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、舌癌の悪性化に関与する。2023

Author(s)

Organizer

Data Source

[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、膵癌細胞の悪性形質の促進に関与する2022

Author(s)

Organizer

Data Source

[Presentation] レチノイン酸代謝酵素CYP26A1の異常発現は、膵癌細胞の悪性形質の促進に関与する。2022

Author(s)

Organizer

Data Source

[Presentation] タイト結合関連分子claudin-18は、レチノイン酸欠乏を原因とする乳がん悪性化に関与する2019

Author(s)

Organizer

Data Source

ONO YUSUKE 小野佑輔

Ono Yusuke 小野佑輔