Fujino Toshio 藤野智大

Researcher Number	90813981
Other IDs
Affiliation (based on the past Project Information) *help	2021: 近畿大学, 医学部, 助教 2019 – 2020: 近畿大学, 大学病院, 専攻医
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 二次変異 / MET / EGFR / MET exon 14 skipping変異 / ドライバー遺伝子変異 / CBL変異 / 耐性機序 / チロシンキナーゼ阻害剤 / MET exon 14遺伝子変異 / 獲得耐性 … More / 初期耐性 / 耐性二次変異 / MET-TKI / MET exon14 skipping変異 / 獲得耐性変異 / MET遺伝子変異 / 分子標的治療 / 非小細胞肺癌 Less

Analysis of CBL gene mutations as a novel therapeutic target for lung cancerPrincipal Investigator
- Principal Investigator
  
  藤野智大
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
Development of new treatment strategy for lung cancer haboring MET exon14 mutationPrincipal Investigator
- Principal Investigator
  
  Fujino Toshio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University

All 2022 2021 2020 2019

All Journal Article Presentation Book Patent

[Book] 呼吸器ジャーナル2020
- Author(s)
  藤野智大, 須田健一, 光冨徹哉
- Total Pages
  8
- Publisher
  医学書院
- ISBN
  4260029029
- Data Source
  KAKENHI-PROJECT-19K16813
[Journal Article] Intra-tumor and Inter-tumor Heterogeneity in MET Exon 14 Skipping Mutations and Co-mutations in Pulmonary Pleomorphic Carcinomas2021
- Author(s)
  Fujino Toshio、Suda Kenichi、Sakai Kazuko、Murakami Isao、Shimizu Shigeki、Ohara Shuta、Koga Takamasa、Hamada Akira、Soh Junichi、Nishio Kazuto、Mitsudomi Tetsuya
- Journal Title
  
  Clinical Lung Cancer
  
  Volume: - Issue: 3 Pages: e185-e195
- DOI
  10.1016/j.cllc.2021.09.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16813, KAKENHI-PROJECT-21K15580
[Journal Article] Lung Cancer with MET exon 14 Skipping Mutation: Genetic Feature, Current Treatments, and Future Challenges.2021
- Author(s)
  Fujino T, Suda K, Mitsudomi T.
- Journal Title
  
  Lung Cancer: Targets and Therapy
  
  Volume: 12 Pages: 35-50
- DOI
  10.2147/lctt.s269307
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07336, KAKENHI-PROJECT-19K16813, KAKENHI-PROJECT-21K15580
[Journal Article] Acquired Resistance Mechanism for MET Tyrosine Kinase Inhibitor2021
- Author(s)
  Fujino Toshio、Mitsudomi Tetsuya
- Journal Title
  
  JTO Clinical and Research Reports
  
  Volume: 2 Issue: 3 Pages: 100134-100134
- DOI
  10.1016/j.jtocrr.2020.100134
- Open Access
- Data Source
  KAKENHI-PROJECT-19K16813, KAKENHI-PROJECT-21K15580
[Journal Article] Emerging MET tyrosine kinase inhibitors for the treatment of non-small cell lung cancer2020
- Author(s)
  Fujino T, Suda K, Mitsudomi T
- Journal Title
  
  Expert Opinion on Emerging Drugs
  
  Volume: 25 Issue: 3 Pages: 229-249
- DOI
  10.1080/14728214.2020.1791821
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07336, KAKENHI-PROJECT-19K16813
[Patent] タイプＩ型抗がん剤に耐性を獲得した肺癌用治療薬2021
- Inventor(s)
  藤野智大、光冨徹哉
- Industrial Property Rights Holder
  藤野智大、光冨徹哉
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21K15580
[Patent] タイプI型抗がん剤に耐性を獲得した肺癌用治療薬2021
- Inventor(s)
  藤野智大、光冨徹哉
- Industrial Property Rights Holder
  藤野智大、光冨徹哉
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K16813
[Patent] タイプＩ型抗がん剤に耐性を獲得した肺癌用治療薬2021
- Inventor(s)
  藤野智大、光冨徹哉
- Industrial Property Rights Holder
  藤野智大、光冨徹哉
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] Treatment strategy of lung cancer with MET, NTRK and BRAF gene aberrations: Insights from in vitro and clinical data2022
- Author(s)
  Toshio Fujino, Kenichi Suda and Tetsuya Mitsudomi
- Organizer
  2022 the Japanese Society of Medical Oncology Annual Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-21K15580
[Presentation] Treatment strategy of lung cancer with MET, NTRK and BRAF gene aberrations: Insights from in vitro and clinical data2022
- Author(s)
  Toshio Fujino, Kenichi Suda and Tetsuya Mitsudomi
- Organizer
  2022 the Japanese Society of Medical Oncology Annual Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] MET exon 14 skipping変異肺癌におけるType I MET-TKI耐性二次的変異とその克服2021
- Author(s)
  藤野智大、須田健一、小原秀太、濱田顕、千葉眞人、下治正樹、武本智樹、宗淳一、光冨徹哉
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15580
[Presentation] MET exon14 skipping変異陽性肺多形癌における intra-およびinter-tumor heterogeneityの検討2021
- Author(s)
  藤野智大、須田健一、坂井和子、清水重喜、村上功、小原秀太、古賀教将、西野将矢、濱田顕、千葉眞人、武本智樹、宗淳一、西尾和人、光冨徹哉
- Organizer
  第121回　日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] Dysregulation of MET: its significance in carcinogenesis and treatment of lung cancer2021
- Author(s)
  Toshio Fujino, Kenichi Suda and Tetsuya Mitsudomi
- Organizer
  The 62nd Annual Meeting of the Japan Lung Cancer Society
- Invited
- Data Source
  KAKENHI-PROJECT-21K15580
[Presentation] Dysregulation of MET: its significance in carcinogenesis and treatment of lung cancer2021
- Author(s)
  Toshio Fujino, Kenichi Suda and Tetsuya Mitsudomi
- Organizer
  The 62nd Annual Meeting of the Japan Lung Cancer Society
- Invited
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] MET exon 14 skipping変異肺癌におけるType I MET-TKI耐性二次的変異とその克服2021
- Author(s)
  藤野智大、須田健一、小原秀太、濱田顕、千葉眞人、下治正樹、武本智樹、宗淳一、光冨徹哉
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] MET遺伝子変異陽性肺癌の病態と MET-TKIに対する感受性と耐性機序2020
- Author(s)
  藤野智大
- Organizer
  第61回日本肺癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] MET exon14 skipping変異陽性多形癌におけるInter-tumor Heterogeneityの検討2019
- Author(s)
  藤野　智大
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16813
[Presentation] Comprehensive analysis of secondary mutation as resistance mechanism to seven MET-TKIs for MET exon 14 skipping in vitro2019
- Author(s)
  Toshio Fujino
- Organizer
  20th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16813

1. 須田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Fujino Toshio 藤野 智大

Research Projects

Research Products

Co-Researchers

Analysis of CBL gene mutations as a novel therapeutic target for lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new treatment strategy for lung cancer haboring MET exon14 mutationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 呼吸器ジャーナル2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Intra-tumor and Inter-tumor Heterogeneity in MET Exon 14 Skipping Mutations and Co-mutations in Pulmonary Pleomorphic Carcinomas2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lung Cancer with MET exon 14 Skipping Mutation: Genetic Feature, Current Treatments, and Future Challenges.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acquired Resistance Mechanism for MET Tyrosine Kinase Inhibitor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Emerging MET tyrosine kinase inhibitors for the treatment of non-small cell lung cancer2020

Author(s)

Journal Title

DOI

Data Source

[Patent] タイプＩ型抗がん剤に耐性を獲得した肺癌用治療薬2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] タイプI型抗がん剤に耐性を獲得した肺癌用治療薬2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] タイプＩ型抗がん剤に耐性を獲得した肺癌用治療薬2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Treatment strategy of lung cancer with MET, NTRK and BRAF gene aberrations: Insights from in vitro and clinical data2022

Author(s)

Organizer

Data Source

[Presentation] Treatment strategy of lung cancer with MET, NTRK and BRAF gene aberrations: Insights from in vitro and clinical data2022

Author(s)

Organizer

Data Source

[Presentation] MET exon 14 skipping変異肺癌におけるType I MET-TKI耐性二次的変異とその克服2021

Author(s)

Organizer

Data Source

[Presentation] MET exon14 skipping変異陽性肺多形癌における intra-およびinter-tumor heterogeneityの検討2021

Author(s)

Organizer

Data Source

[Presentation] Dysregulation of MET: its significance in carcinogenesis and treatment of lung cancer2021

Author(s)

Organizer

Data Source

Fujino Toshio 藤野智大