Maeda Ryo 前田亮

Researcher Number	90814575
Other IDs
Affiliation (Current)	2022: 大阪大学, 大学院生命機能研究科, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2021: 大阪大学, 生命機能研究科, 特任助教(常勤) 2019 – 2020: 大阪大学, 生命機能研究科, 特別研究員(PD) 2018: 徳島大学, 先端酵素学研究所(次世代), 特別研究員(PD) 2017 – 2018: 徳島大学, 先端酵素学研究所, 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related Except Principal Investigator Molecular biology
Keywords	Principal Investigator ヘテロクロマチン / HP1 / H3K9メチル化 / レトロトランスポゾン / 転写制御 / H3K9me3 Except Principal Investigator がん抑制遺伝子 / p53 / 転写制御 / TLP … More / transcription factor / MDM2 / HP1 / ヘテロクロマチン / H3K9me3 / H3K9メチル化 / ES細胞 / 体細胞分裂 Less

ほ乳類におけるHP1依存的なヘテロクロマチン形成機構の解明Principal Investigator
- Principal Investigator
  
  前田亮
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Osaka University
Molecular mechanism of heterochromatin patterning involved in gene regulationPrincipal Investigator
- Principal Investigator
  
  Maeda Ryo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Osaka University
  The University of Tokushima
ＥＳ細胞における染色体構造の安定性を担保するヘテロクロマチン形成機構Research Fellow
- Research Fellow
  
  前田亮
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Molecular biology
- Research Institution
  Osaka University
  The University of Tokushima
ｐ５３のがん抑制機構における転写因子ＴＬＰの機能の解明Research Fellow
- Research Fellow
  
  前田亮
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokushima
  Chiba University

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] H3K9 demethylases JMJD1A and JMJD1B control prospermatogonia to spermatogonia transition in mouse germline2020
- Author(s)
  Kuroki Shunsuke、Maeda Ryo、Yano Masashi、Kitano Satsuki、Miyachi Hitoshi、Fukuda Mikiko、Shinkai Yoichi、Tachibana Makoto
- Journal Title
  
  Stem Cell Reports
  
  Volume: 15 Pages: 424438-424438
- DOI
  10.1016/j.stemcr.2020.06.013
- NAID
  120007146093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05364, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-20H03262, KAKENHI-PROJECT-18J00586, KAKENHI-PROJECT-19K22388
[Journal Article] The mouse Sry locus harbors a cryptic exon that is essential for male sex determination2020
- Author(s)
  Miyawaki Shingo、Kuroki Shunsuke、Maeda Ryo、Okashita Naoki、Koopman Peter、Tachibana Makoto
- Journal Title
  
  Science
  
  Volume: 370 Pages: 121124-121124
- DOI
  10.1126/science.abb6430
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05364, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-20H03262, KAKENHI-PROJECT-18J00586, KAKENHI-PROJECT-20J40132, KAKENHI-PROJECT-19K22388, KAKENHI-PROJECT-19K16490
[Journal Article] DNA demethylation of the Sry promoter and enhances its expression2019
- Author(s)
  Okashita N, Kuroki S, Maeda R, *Tachibana M.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Pages: 13462-13462
- DOI
  10.1038/s41598-019-50058-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22388, KAKENHI-PROJECT-18J00586, KAKENHI-PROJECT-18K14675, KAKENHI-PROJECT-18K14676
[Journal Article] Combined loss of Jmjd1a and Jmjd1b reveals critical roles for H3K9 demethylation in the maintenance of embryonic stem cells and early embryogenesis2018
- Author(s)
  Kuroki, S., Nakai, Y., Maeda, R., Okashita, N., Akiyoshi, M., Yamaguchi, Y., Kitano, S., Miyachi, H., Nakato, R., Ichiyanagi, K., Shirahige, K., Kimura, H., Shinkai, Y., and Tachibana, M.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Pages: 1340-1354
- DOI
  10.1016/j.stemcr.2018.02.002
- NAID
  120006463740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07726, KAKENHI-PROJECT-18K14675, KAKENHI-PROJECT-18K14676, KAKENHI-ORGANIZER-17H06423, KAKENHI-PROJECT-16H04817, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-18J00586, KAKENHI-PLANNED-17H06424
[Journal Article] TBP-like protein (TLP) disrupts the p53-MDM2 interaction and induces long-lasting p53 activation.2017
- Author(s)
  Maeda R., Tamashira H., Takano K., Takahashi H., Suzuki H., Saito S., Hojima W., Adachi N., U ra K ., E ndo T . and *Tam ura T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Pages: 3201-3212
- DOI
  10.1074/jbc.m116.763318
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01345, KAKENHI-PROJECT-15H04323, KAKENHI-PROJECT-15H04348, KAKENHI-PROJECT-15J02670, KAKENHI-PROJECT-16J04091, KAKENHI-PROJECT-26440045
[Journal Article] Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA2016
- Author(s)
  Isogai M, Suzuki H, Maeda R, Tamura T.
- Journal Title
  
  Gene
  
  Volume: 21 Pages: 1223-1232
- DOI
  10.1111/gtc.12441
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J02670, KAKENHI-PROJECT-16J04091
[Journal Article] TBP-like protein (TLP) represses myogenesis via inhibition of the myogenin promoter.2016
- Author(s)
  Nakazato A, Maeda R, Ishikawa K, Suzuki H, Tamura T
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 479 Pages: 814-819
- DOI
  10.1016/j.bbrc.2016.09.127
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J02670, KAKENHI-PROJECT-16J04091
[Journal Article] TBP-like protein (TLP) interferes with Taspase1-mediated processing of TFIIA and represses TATA box gene expression2015
- Author(s)
  Suzuki H, Isogai M, Maeda R, Ura K, Tamura T.
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 43 Pages: 6285-6298
- DOI
  10.1093/nar/gkv576
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J02670, KAKENHI-PROJECT-13J04583, KAKENHI-PROJECT-24570193, KAKENHI-PLANNED-22131003, KAKENHI-PUBLICLY-15H01345
[Presentation] H3K9メチル化hubとしてはたらくHP1の機能2019
- Author(s)
  前田亮
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K14675
[Presentation] H3K9メチル化hubとしてはたらくHP1の機能2019
- Author(s)
  前田　亮
- Organizer
  分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18J00586
[Presentation] ES細胞におけるレトロトランスポゾンを起点とした転写抑制領域の構築機構2017
- Author(s)
  前田亮
- Organizer
  生命情報若手の会第9回研究会
- Data Source
  KAKENHI-PROJECT-15J02670
[Presentation] p53-TLP相互作用：MDM2の機能抑制によるp53活性化維持機構2016
- Author(s)
  前田亮
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-15J02670
[Presentation] Competitive p53 Binding of TBP-Like Protein (TLP) Against MDM2 Induces Stabilization of p53 and Promotes p53-Mediated Cell Growth Regulation2015
- Author(s)
  Ryo Maeda
- Organizer
  8th International MDM2 Workshop
- Place of Presentation
  ニューオリンズ（アメリカ合衆国）
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J02670
[Presentation] MDM2との結合競合を介した転写因子TLPによるp53安定化機構2015
- Author(s)
  前田亮
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアリーナ（兵庫県・神戸市）
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-15J02670

1. TAKANO Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. NAKAI Yuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. ICHIYANAGI Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. Ichiyanagi Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 田村隆明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 青田聖恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 足立典隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 遠藤剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高野晴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 黒木俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 立花誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 宮脇慎吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maeda Ryo 前田 亮

Research Projects

Research Products

Co-Researchers

ほ乳類におけるHP1依存的なヘテロクロマチン形成機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of heterochromatin patterning involved in gene regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ＥＳ細胞における染色体構造の安定性を担保するヘテロクロマチン形成機構Research Fellow

Research Fellow

Project Period (FY)

Research Category

Research Field

Research Institution

ｐ５３のがん抑制機構における転写因子ＴＬＰの機能の解明Research Fellow

Research Fellow

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] H3K9 demethylases JMJD1A and JMJD1B control prospermatogonia to spermatogonia transition in mouse germline2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The mouse Sry locus harbors a cryptic exon that is essential for male sex determination2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA demethylation of the Sry promoter and enhances its expression2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined loss of Jmjd1a and Jmjd1b reveals critical roles for H3K9 demethylation in the maintenance of embryonic stem cells and early embryogenesis2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] TBP-like protein (TLP) disrupts the p53-MDM2 interaction and induces long-lasting p53 activation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ubiquitin-proteasome-dependent degradation of TBP-like protein is prevented by direct binding of TFIIA2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TBP-like protein (TLP) represses myogenesis via inhibition of the myogenin promoter.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TBP-like protein (TLP) interferes with Taspase1-mediated processing of TFIIA and represses TATA box gene expression2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] H3K9メチル化hubとしてはたらくHP1の機能2019

Author(s)

Organizer

Data Source

[Presentation] H3K9メチル化hubとしてはたらくHP1の機能2019

Author(s)

Organizer

Data Source

[Presentation] ES細胞におけるレトロトランスポゾンを起点とした転写抑制領域の構築機構2017

Author(s)

Maeda Ryo 前田亮