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Takai Tomoko  高井 智子

ORCIDConnect your ORCID iD *help
Researcher Number 90823047
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学研究科, 医学研究員
Affiliation (based on the past Project Information) *help 2024: 神戸大学, 医学研究科, 医学研究員
2023: 神戸大学, 医学研究科, 特命助教
2022: 神戸大学, 医学研究科, 学術研究員
2020: 神戸大学, 医学研究科, 学術研究員
2020: 神戸大学, 医学部附属病院, 学術研究員
2019: 神戸大学, シグナル統合学, 学術研究員
Review Section/Research Field
Principal Investigator
Basic Section 49010:Pathological biochemistry-related / Basic Section 54040:Metabolism and endocrinology-related
Keywords
Principal Investigator
CD47 / 生細胞貪食 / 樹状細胞 / マクロファージ / SIRPα / CK2 / 小胞体ストレス / 2型糖尿病
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (1 People)
  •  膜型分子CD47によるマクロファージの細胞貪食制御機構とその分子機序の解明Principal Investigator

    • Principal Investigator
      高井 智子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kobe University
  •  Importance of dendritic cells in the elimination of CD47-deficient erythrocytesPrincipal Investigator

    • Principal Investigator
      Takai Tomoko
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Kobe University
  •  Role of CK2 in unfolded protein respose in pancreatic beta cellsPrincipal Investigator

    • Principal Investigator
      Takai Tomoko
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Kobe University

All 2023 2022 2019

All Journal Article Presentation

  • [Journal Article] Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes2019

    • Author(s)
      Kanno A, Asahara SI, Kawamura M, Furubayashi A, Tsuchiya S, Suzuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Okada Y, Ogawa W, Kido Y.
    • Journal Title

      J Diabetes Invest.

      Volume: 10 Issue: 3 Pages: 577-590

    • DOI

      10.1111/jdi.12945

    • NAID

      120006645694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09882, KAKENHI-PROJECT-17H01966, KAKENHI-PROJECT-16K09803, KAKENHI-PROJECT-19K17963
  • [Presentation] CD47欠損細胞の排除における樹状細胞の重要性2023

    • Author(s)
      高井智子
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] 細胞間シグナルCD47-SIRPα系による細胞貪食制御機序とその新規がん治療法への応用2022

    • Author(s)
      小谷 武徳、高井智子、小森里美、齊藤 泰之、村田 陽二、的崎 尚
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] マクロファージ SIRPβ1を標的とした新たながん免疫療法2022

    • Author(s)
      村田陽二、坂本茉莉子、高井智子、齊藤泰之、小谷武徳、的崎尚
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] マクロファージによるがん細胞貪食を制御する分子基盤の解明2022

    • Author(s)
      小谷武徳、高井智子、齊藤泰之、村田陽二、的崎尚
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] SIRPαand CD47 promote cDC2 survival through the regulation of transcriptional factor Nr4a32022

    • Author(s)
      Satomi Komori, Yasuyuki Saito, Taichi Nishimura, Hiroki Yoshida, Risa Sugihara, Tomoko Takai, Takenori Kotani, Yoji Murata, Takashi Matozaki
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] Dendritic cells regulate peripheral T cell survival through the CD47-SIRPαsignaling2022

    • Author(s)
      Yasuyuki Saito, Satomi Komori, Hiroki Yoshida, risa Sugihara, Tomoko Takai, Takenori Kotani, Yoji Murata, Takashi Matozaki
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K15395
  • [Presentation] 膵β細胞のUnfolded protein responseにおけるCK2の役割2019

    • Author(s)
      高井智子 松田友和 木村真希 浅原俊一郎 木戸良明
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K17963
  • [Presentation] 膵β細胞のUnfolded protein responseにおけるCK2の役割2019

    • Author(s)
      高井智子 井上佳歩 松田友和 木村真希 浅原俊一郎 木戸良明
    • Organizer
      第56回日本臨床分子医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K17963
  • 1.  淺原 俊一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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