Fukuda Ryosuke 福田亮介

Researcher Number	90825308
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 関西学院大学, 生命環境学部, 助教 2019 – 2020: 関西学院大学, 理工学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 49070:Immunology-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator 呼吸器炎症 / 気道上皮細胞 / 炎症 / タンパク質間相互作用 / 気道上皮炎症応答 / CFTR / 嚢胞性線維症 / 上皮細胞炎症応答 / 膜タンパク質 / 細菌・ウィルス感染 … More / 細胞間接着 / 上皮細胞炎症 / ADAM9 / Ephrinリガンド / EPH受容体 / 細胞間シグナル … More Except Principal Investigator ユビキチン / ユビキチンリガーゼ / タンパク質品質管理 / 膜タンパク質 / 小胞体品質管理 / retrotranslocation / 逆輸送 / ERAD / 形質膜 / CFTR / 嚢胞性線維症 / DUB / ユビキチン化 Less

哺乳類 ERAD における逆輸送機構の包括的理解
- Principal Investigator
  
  沖米田司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kwansei Gakuin University
細胞間接着介在性EPH-EFN結合の選択的解離を利用した新規病原体認識機構の解明Principal Investigator
- Principal Investigator
  
  福田亮介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kwansei Gakuin University
Elucidation and therapeutic application of ubiquitination mechanisms in the PMQC
- Principal Investigator
  
  Okiyoneda Tsukasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Kwansei Gakuin University
Physiological role of CFTR interaction receptor under sterile inflammatory response in cystic fibrosisPrincipal Investigator
- Principal Investigator
  
  Fukuda Ryosuke
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kwansei Gakuin University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains2024
- Author(s)
  Yuka Kamada, Yuko Ohnishi, Chikako Nakashima, Aika Fujii, Mana Terakawa, Ikuto Hamano, Uta Nakayamada, Saori Katoh, Noriaki Hirata, Hazuki Tateishi, Ryosuke Fukuda, Hirotaka Takahashi, Gergely L. Lukacs, Tsukasa Okiyoneda
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 223(7) Issue: 7
- DOI
  10.1083/jcb.202308003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23840
[Journal Article] The multiple ubiquitination mechanisms in CFTR peripheral quality control2023
- Author(s)
  Taniguchi Shogo、Fukuda Ryosuke、Okiyoneda Tsukasa
- Journal Title
  
  Biochemical Society Transactions
  
  Volume: 51 Issue: 3 Pages: 1297-1306
- DOI
  10.1042/bst20221468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23840, KAKENHI-PUBLICLY-21H00294
[Journal Article] Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis2023
- Author(s)
  Taniguchi Sachiho、Ono Yuji、Doi Yukako、Taniguchi Shogo、Matsuura Yuta、Iwasaki Ayuka、Hirata Noriaki、Fukuda Ryosuke、Inoue Keitaro、Yamaguchi Miho、Tashiro Anju、Egami Daichi、Aoki Shunsuke、Kondoh Yasumitsu、Honda Kaori、Osada Hiroyuki、Kumeta Hiroyuki、Saio Tomohide、Okiyoneda Tsukasa
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 215 Pages: 115730-115730
- DOI
  10.1016/j.bcp.2023.115730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23840
[Journal Article] UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR2023
- Author(s)
  Kamada Yuka、Tateishi Hazuki、Nakayamada Uta、Hinata Daichi、Iwasaki Ayuka、Zhu Jingxin、Fukuda Ryosuke、Okiyoneda Tsukasa
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 23 Pages: 2741-2741
- DOI
  10.3390/cells12232741
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23840
[Journal Article] The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)2022
- Author(s)
  Taniguchi Shogo、Ito Yukiko、Kiritani Hibiki、Maruo Asuka、Sakai Ryohei、Ono Yuji、Fukuda Ryosuke、Okiyoneda Tsukasa
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 9
- DOI
  10.3389/fmolb.2022.840649
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03185, KAKENHI-PUBLICLY-21H00294
[Journal Article] CFTR protein quality control mechanism and its modulation for therapeutic approaches2020
- Author(s)
  福田亮介、沖米田司
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 2 Pages: 179-188
- DOI
  10.14952/SEIKAGAKU.2020.920179
- NAID
  40022245229
- ISSN
  0037-1017
- Year and Date
  2020-04-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19H03185, KAKENHI-PUBLICLY-19H05300
[Journal Article] Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis2020
- Author(s)
  Fukuda Ryosuke、Okiyoneda Tsukasa
- Journal Title
  
  Pharmaceuticals
  
  Volume: 13 Issue: 4 Pages: 75-75
- DOI
  10.3390/ph13040075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03185, KAKENHI-PUBLICLY-19H05300
[Journal Article] 嚢胞性線維症における上皮細胞の水の輸送障害を理解する2019
- Author(s)
  福田亮介, 沖米田司
- Journal Title
  
  消化器病学サイエンス
  
  Volume: 3 Pages: 82-86
- Data Source
  KAKENHI-PROJECT-19H03185
[Journal Article] ELISA Based Protein Ubiquitylation Measurement2019
- Author(s)
  Kamada Yuka、Fukuda Ryosuke、Okiyoneda Tsukasa
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 9 Issue: 22
- DOI
  10.21769/bioprotoc.3430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05300, KAKENHI-PROJECT-19H03185
[Presentation] sgRNAゲノムワイドスクリーニングによる新規CFTR品質管理分子の同定2023
- Author(s)
  谷口正伍, 三村文菜, 福田亮介, 木塚康彦, 沖米田司
- Organizer
  第46回日本分子生物学会年会シンポジウム2PS-17 遅延制御による脳機能障害および神経変性疾患の理解
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] EPH 受容体-EFN リガンド細胞間相互作用を介した気道上皮細胞の炎症制御機構の解明2023
- Author(s)
  福田亮介, 日向大智, 別府史織, 沖米田司
- Organizer
  第143回薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15475
[Presentation] EPH 受容体-EFNリガンドの細胞間 trans 結合を介した気道上皮細胞の炎症増幅機構の解明2023
- Author(s)
  福田亮介, 日向大智, 別府史織, 沖米田司
- Organizer
  2023年度　生理研研究会
- Data Source
  KAKENHI-PROJECT-21K15475
[Presentation] 小胞体関連ユビキチン E3 リガーゼ Gp78 と Hrd1 の阻害剤探索2023
- Author(s)
  平田規晃，川谷誠、本田香織、長田裕之、福田亮介、沖米田司
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] 小胞体関連分解を標的とした嚢胞性線維症の治療法開発2023
- Author(s)
  鎌田優香, 松浦佑大, 谷口幸穂, 西井一真, 中山田詠, 立石葉月, 日向大智, 福田亮介, 川谷誠, 本田香織, 長田裕之, 沖米田司
- Organizer
  第46回日本分子生物学会年会シンポジウム 2PS-06 アカデミア創薬
- Invited
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] HECT 型 E3 リガーゼは UBQLN を動員して異常膜タンパク質の小胞体関連分解を促進する2022
- Author(s)
  鎌田優香、藤井愛日、中島千雅子、大西裕子、寺川真奈、濱野伊玖斗、福田亮介、沖米田司
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] CFTR 関連ユビキチンリガーゼの阻害剤探索と治療的応用2022
- Author(s)
  松浦佑大、谷口幸穂、小野裕司、土井由佳子、近藤恭光、本田香織、長田裕之、井上敬太郎、山口美穂、田代杏樹、青木俊介、福田亮介、沖米田司
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H03185
[Presentation] CFTR 変異体の小胞体関連分解におけるバイパス機構の解明2022
- Author(s)
  藤井愛日, 鎌田優香, 福田亮介, 沖米田司
- Organizer
  第95回日本生化学学会大会
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] A HECT type E3 ligase facilitates the ERAD of aberrant membrane proteins by recruiting UBQLN2022
- Author(s)
  Yuka Kamada, Aika Fujii, Ikuto Hamano, Ryosuke Fukuda, Tsukasa Okiyoneda
- Organizer
  The International Symposium in Tokyo 2022. Ubiquitin New Frontier“ from Neo-Biology to Targeted Protein Degradation”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23840
[Presentation] CFTR 形質膜品質管理における RING 型 E3 Ligase CARP1 の機能解析2021
- Author(s)
  谷口正伍、酒井了平、丸尾明日香、桐谷響暉、福田亮介、沖米田司
- Organizer
  2021年度生理研研究会『上皮膜輸送の多様性・調和機構を基盤とする異分野融合研究の創出』
- Data Source
  KAKENHI-PROJECT-19H03185
[Presentation] 塩素イオンチャネル CFTR 変異体の小胞体関連分解における HECT 型ユビキチンリガーゼの機能解析2020
- Author(s)
  鎌田優香、中島千雅子、福田亮介、沖米田司
- Organizer
  2020年度生理研研究会『上皮膜輸送の多様性・調和機構を基盤とする異分野融合研究の創出』
- Data Source
  KAKENHI-PROJECT-19H03185
[Presentation] 嚢胞性線維症治療薬開発を目指した RFFL ユビキチンリガーゼ PPI 阻害剤の探索2019
- Author(s)
  沖米田司、酒井了平、宗岡聡、永平亜佐子、冨森嘉晃、東桃子、宇仁田伸、小野裕司、福田亮介
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03185
[Presentation] CFTR相互作用分子解析に基づく気道上皮非感染性炎症応答機構の解明2019
- Author(s)
  福田亮介
- Organizer
  2019年度生理研研究会
- Data Source
  KAKENHI-PROJECT-19K16508

1. Okiyoneda Tsukasa (90398248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. 高橋宏隆 (70432804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 中村照也 (40433015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石黒洋 (90303651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Fukuda Ryosuke 福田 亮介

Research Projects

Research Products

Co-Researchers

哺乳類 ERAD における逆輸送機構の包括的理解

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞間接着介在性EPH-EFN結合の選択的解離を利用した新規病原体認識機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation and therapeutic application of ubiquitination mechanisms in the PMQC

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological role of CFTR interaction receptor under sterile inflammatory response in cystic fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The multiple ubiquitination mechanisms in CFTR peripheral quality control2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of α-Tocopherol succinate as an RFFL-substrate interaction inhibitor inducing peripheral CFTR stabilization and apoptosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] UBE3C Facilitates the ER-Associated and Peripheral Degradation of Misfolded CFTR2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Ubiquitin Ligase RNF34 Participates in the Peripheral Quality Control of CFTR (RNF34 Role in CFTR PeriQC)2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CFTR protein quality control mechanism and its modulation for therapeutic approaches2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 嚢胞性線維症における上皮細胞の水の輸送障害を理解する2019

Author(s)

Journal Title

Data Source

[Journal Article] ELISA Based Protein Ubiquitylation Measurement2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] sgRNAゲノムワイドスクリーニングによる新規CFTR品質管理分子の同定2023

Author(s)

Organizer

Data Source

Fukuda Ryosuke 福田亮介

[Presentation] CFTR相互作用分子解析に基づく気道上皮非感染性炎症応答機構の解明2019