Yamamoto Yoshinari 山本祥也

Researcher Number	90825845
Other IDs
Affiliation (Current)	2025: 広島大学, 統合生命科学研究科(生), 助教
Affiliation (based on the past Project Information) *help	2025: 広島大学, 統合生命科学研究科(生), 助教 2021 – 2023: 広島大学, 統合生命科学研究科(生), 助教 2019: 広島大学, 統合生命科学研究科(生), 助教 2018: 広島大学, 生物圏科学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 42030:Animal life science-related / 0605:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator リポ多糖 / 表層タンパク質 / 乳酸菌 / DNanocap / DNAナノカプセル / 腸管恒常性 / 相互作用 / 抗炎症機構 / 感染症 / 免疫 … More / マウス / 免疫グロブリンA / 経口粘膜アジュバント / Class A CpGオリゴDNA / 自由摂取 / 血小板活性化因子アセチルヒドロラーゼ / オリゴDNA / 敗血症 / 機能性食品 / PAF-AH / Class A CpG ODN Less

Research Projects
(4 results)
Research Products
(15 results)

リポ多糖結合型の乳酸菌表層タンパク質による腸管恒常性制御機構の解明Principal Investigator
- Principal Investigator
  
  山本祥也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hiroshima University
Elucidation of anti-inflammatory mechanism of surface layer protein of lactic acid bacteria focusing on its interaction with lipopolysaccharide.Principal Investigator
- Principal Investigator
  
  山本祥也
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Hiroshima University
Development of oral mucosal adjuvant using Class A CpG ODN-nanocapusulePrincipal Investigator
- Principal Investigator
  
  Yamamoto Yoshinari
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Hiroshima University
Development of functional food for sepsis using oligodeoxynucleotide nano capsulePrincipal Investigator
- Principal Investigator
  
  Yamamoto Yoshinari
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0605:Veterinary medical science, animal science, and related fields
- Research Institution
  Hiroshima University

All 2024 2023 2019 2018

All Journal Article Presentation

[Journal Article] Lentilactobacillus hilgardii H-50 strongly inhibits lipopolysaccharide-induced inflammatory responses in mouse splenocytes via its specific surface layer proteins2023
- Author(s)
  Yamaguchi Tomofumi、Yasui Kenta、Fujii Sotaro、Ichikawa Kennosuke、Suzuki Takuya、Sambongi Yoshihiro、Yamamoto Yoshinari
- Journal Title
  
  Journal of Applied Microbiology
  
  Volume: 134 Issue: 3
- DOI
  10.1093/jambio/lxad021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14997
[Journal Article] Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD112023
- Author(s)
  Ichikawa Kennosuke、Matsuzaki Mei、Ezaki Ryo、Horiuchi Hiroyuki、Yamamoto Yoshinari
- Journal Title
  
  J. Poult. Sci.
  
  Volume: 60 Issue: 1 Pages: n/a
- DOI
  10.2141/jpsa.2023002
- ISSN
  1346-7395, 1349-0486
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K14997
[Journal Article] Exopolysaccharides from Leuconostoc mesenteroides attenuate chronic kidney disease in mice by protecting the intestinal barrier2019
- Author(s)
  Hung Tran Van、Wanatanbe Jun、Yonejima Yasunori、Hisa Keiko、Yamamoto Yoshinari、Suzuki Takuya
- Journal Title
  
  Journal of Functional Foods
  
  Volume: 52 Pages: 276-283
- DOI
  10.1016/j.jff.2018.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21168
[Journal Article] Naringenin promotes recovery from colonic damage through suppression of epithelial tumor necrosis factor-α production and induction of M2-type macrophages in colitic mice2019
- Author(s)
  Chaen Yuta、Yamamoto Yoshinari、Suzuki Takuya
- Journal Title
  
  Nutrition Research
  
  Volume: 64 Pages: 82-92
- DOI
  10.1016/j.nutres.2019.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21168
[Journal Article] Recombinant mouse calcitonin gene-related peptide secreted by Lactococcus lactis inhibits lipopolysaccharide-induced inflammatory response in macrophages2018
- Author(s)
  Namai Fu、Yamamoto Yoshinari、Sato Takashi、Ogita Tasuku、Shimosato Takeshi
- Journal Title
  
  Animal Science Journal
  
  Volume: 89 Issue: 12 Pages: 1707-1711
- DOI
  10.1111/asj.13115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21168
[Journal Article] Immune synergistic oligodeoxynucleotide from Lactobacillus rhamnosus GG enhances the immune response upon co-stimulation by bacterial and fungal cell wall components2018
- Author(s)
  Nigar Shireen、Yamamoto Yoshinari、Okajima Takuma、Sato Takashi、Ogita Tasuku、Shimosato Takeshi
- Journal Title
  
  Animal Science Journal
  
  Volume: 89 Issue: 10 Pages: 1504-1511
- DOI
  10.1111/asj.13082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] リポ多糖との相互作用に着目した乳酸菌表層タンパク質の生理学的役割の解明2024
- Author(s)
  山本祥也, 安井健太, 鈴木卓弥
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K13905
[Presentation] Lentilactobacillus hilgardii strain H-50の炎症応答抑制作用機構の解明2023
- Author(s)
  安井健太, 鈴木卓弥, 山本祥也
- Organizer
  2023年酪農シンポジウム
- Data Source
  KAKENHI-PROJECT-23K13905
[Presentation] A型オリゴDNAの自由摂取による生体防御機能への影響2019
- Author(s)
  石丸　絢也香、鈴木　卓弥、山本　祥也
- Organizer
  第52回日本栄養・食糧学会中国・四国支部大会
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] Flavonifractor plautiiの経口投与によるTh2免疫応答の抑制効果2019
- Author(s)
  荻田佑、山本祥也、深澤知夏、三上彩音、下里剛士
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] 微生物由来オリゴDNAを用いた生体防御機能を増強する機能性食品・飼料素材の開発2019
- Author(s)
  山本　祥也、石丸　絢也香、鈴木　卓弥
- Organizer
  超異分野学会益田フォーラム2019
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] 乳業用乳酸菌由来オリゴDNAによるCXCL5誘導作用2019
- Author(s)
  ZAYADORJ TSEND-AYUSH、安倍暢大、山本祥也、荻田佑、下里剛士
- Organizer
  日本畜産学会第125回大会
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] 乾癬モデルマウスは腸管のバリア損傷と炎症を引き起こす2018
- Author(s)
  中野智裕、山本祥也、鈴木卓弥
- Organizer
  第51回日本栄養・食糧学会中国・四国支部大会
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] 慢性腎臓病における腸管バリア損傷の分子機序の探索2018
- Author(s)
  赤谷俊亮、山本祥也、鈴木卓弥
- Organizer
  第51回日本栄養・食糧学会中国・四国支部大会
- Data Source
  KAKENHI-PROJECT-19K21168
[Presentation] グァーガム摂取による腸管上皮SOCS1上昇は抗生物質投与により消失する2018
- Author(s)
  御手洗綾、山本祥也、鈴木卓弥
- Organizer
  第51回日本栄養・食糧学会中国・四国支部大会
- Data Source
  KAKENHI-PROJECT-19K21168

Yamamoto Yoshinari 山本 祥也

Research Projects

Research Products

リポ多糖結合型の乳酸菌表層タンパク質による腸管恒常性制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of anti-inflammatory mechanism of surface layer protein of lactic acid bacteria focusing on its interaction with lipopolysaccharide.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of oral mucosal adjuvant using Class A CpG ODN-nanocapusulePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of functional food for sepsis using oligodeoxynucleotide nano capsulePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Lentilactobacillus hilgardii H-50 strongly inhibits lipopolysaccharide-induced inflammatory responses in mouse splenocytes via its specific surface layer proteins2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Screening of Optimal CpG-Oligodeoxynucleotide for Anti-Inflammatory Responses in the Avian Macrophage Cell Line HD112023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Exopolysaccharides from Leuconostoc mesenteroides attenuate chronic kidney disease in mice by protecting the intestinal barrier2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Naringenin promotes recovery from colonic damage through suppression of epithelial tumor necrosis factor-α production and induction of M2-type macrophages in colitic mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recombinant mouse calcitonin gene-related peptide secreted by Lactococcus lactis inhibits lipopolysaccharide-induced inflammatory response in macrophages2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune synergistic oligodeoxynucleotide from Lactobacillus rhamnosus GG enhances the immune response upon co-stimulation by bacterial and fungal cell wall components2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] リポ多糖との相互作用に着目した乳酸菌表層タンパク質の生理学的役割の解明2024

Author(s)

Organizer

Data Source

[Presentation] Lentilactobacillus hilgardii strain H-50の炎症応答抑制作用機構の解明2023

Author(s)

Organizer

Data Source

[Presentation] A型オリゴDNAの自由摂取による生体防御機能への影響2019

Author(s)

Organizer

Data Source

[Presentation] Flavonifractor plautiiの経口投与によるTh2免疫応答の抑制効果2019

Author(s)

Organizer

Data Source

[Presentation] 微生物由来オリゴDNAを用いた生体防御機能を増強する機能性食品・飼料素材の開発2019

Author(s)

Organizer

Data Source

[Presentation] 乳業用乳酸菌由来オリゴDNAによるCXCL5誘導作用2019

Yamamoto Yoshinari 山本祥也