KURIHARA Sho 栗原渉

… Alternative Names

Kurihara Sho 栗原渉

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Researcher Number	90826926
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京慈恵会医科大学, 医学部, 講師 2018 – 2023: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / 0906:Surgery related to the biological and sensory functions and related fields Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 20010:Mechanics and mechatronics-related / Basic Section 56050:Otorhinolaryngology-related / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields / Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 難聴 / オルガノイド / 核酸医薬 / 認知症 / コモンマーモセット / バイオマーカー / アンチセンスオリゴ / ハイドロゲルマイクロビーズ / アポトーシス / 遺伝子治療 … More / 行動学的解析 / MRI / 霊長類モデル / 音響外傷 / 霊長類 / 認知機能 … More Except Principal Investigator 霊長類研究 / 中耳炎 / 聴力回復 / 再建耳小骨 / 有限要素法 / 耳小骨再建 / 伝音特性 / マーモセット / 嗅上皮 / 嗅球 / トラクトグラフィー / 嗅神経 / 治療方針 / 機械学習 / 中耳音響伝搬 / 人工耳小骨 / 最適化 / 中耳再建 / 形状最適化 / 霊長類モデル / hiPS細胞 / IoTセンシング / 内耳性難聴 / 聴覚医学 / 耳科学 / 内耳再生 / バイオインフォマティクス / 橋渡し研究 / 聴覚障害 / iPS細胞創薬 / Caイメージング / 聴覚 / 脳科学 / コモンマーモセット / in vivoイメージング / 脳機能ネットワーク / 聴覚伝導路 / 嗅覚中枢 / 拡散テンソル画像 / 波動数値解析 / 中耳伝音系 / 振動音響伝搬 / 再建モデル / 鼓室形成術 / 耳小骨 / 有限要素法解析 / 耳小骨連鎖 / 加振実験 / 振動音響連成解析 / 耳小骨連載 / 匂いの地図 / DTI / 嗅覚 / 拡散テンソルイメージング / 高磁場MRI機 / 嗅神経分布 / 嗅神経地図 Less

Advancing Novel Therapeutic Approaches for Hearing Loss: Harnessing Human iPSC-Derived Otic Organoids and Innovative Drug Discovery ModalitiesPrincipal Investigator
- Principal Investigator
  
  栗原渉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Jikei University School of Medicine
Development of a treatment for hearing loss using human iPS cell-derived otic organoids and novel antisense oligosPrincipal Investigator
- Principal Investigator
  
  栗原渉
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Jikei University School of Medicine
Integrated understanding of the brain network: from auditory perception
- Principal Investigator
  
  Fujioka Masato
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kitasato University
再建中耳を対象としたトポロジー最適化法による伝音難聴治療の方針決定システムの構築
- Principal Investigator
  
  朝倉巧
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 20010:Mechanics and mechatronics-related
- Research Institution
  Tokyo University of Science
拡散テンソルイメージングを利用した嗅覚中枢の解明
- Principal Investigator
  
  鄭雅誠
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Jikei University School of Medicine
Integrated understanding of inner ear disorders and next-generation drug discovery by combination of IoT sensing and iPSC-based medicine
- Principal Investigator
  
  Fujioka Masato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kitasato University
Functional and structural changes in the brain caused by hearing loss revealed by non-human-primate models and ultra-high field MRIPrincipal Investigator
- Principal Investigator
  
  Kurihara Sho
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Jikei University School of Medicine
Development of an platform for optimization of reconstructed ossicles and its clinical application to ossicular chain reconstruction
- Principal Investigator
  
  Asakura Takumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
- Research Institution
  Tokyo University of Science
Evaluation of biomarkers connecting the hearing loss and dementia using highly social primate modelPrincipal Investigator
- Principal Investigator
  
  Kurihara Sho
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0906:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Jikei University School of Medicine
Visualizing the olfactory map with diffusion tensor imaging: Development of an objective olfactory test method
- Principal Investigator
  
  Tei Masayoshi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Jikei University School of Medicine

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission2023
- Author(s)
  Asakura Takumi、Ito Ryuya、Hirabayashi Motoki、Kurihara Sho、Kurashina Yuta
- Journal Title
  
  Frontiers in Bioengineering and Biotechnology
  
  Volume: 11
- DOI
  10.3389/fbioe.2023.1204972
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K22706
[Journal Article] ヒトiPS細胞由来内耳オルガノイドを用いたシスプラチン障害モデルの解析2022
- Author(s)
  栗原渉, 平林源希, 藤岡正人, 細谷誠, 小島博己
- Journal Title
  
  日本耳鼻咽喉科頭頸部外科学会会報
  
  Volume: 125 Pages: 730-730
- Data Source
  KAKENHI-PROJECT-22K18399
[Journal Article] 小型霊長類コモンマーモセットを用いた聴覚研究2022
- Author(s)
  栗原渉、岡野ジェイムス洋尚、藤岡正人
- Journal Title
  
  BIO Clinica
  
  Volume: 37-2 Pages: 91-93
- Data Source
  KAKENHI-PROJECT-21H04839
[Journal Article] Combined analysis of finite element model and audiometry provides insights into the pathogenesis of conductive hearing loss2022
- Author(s)
  Hirabayashi, M., Kurihara, S., Ito, R., Kurashina, Y., Motegi, M., Okano, H. J., Yamamoto, Y., Kojima, H., & Asakura
- Journal Title
  
  Frontiers in Bioengineering and Biotechnology
  
  Volume: 10 Pages: 1-15
- DOI
  10.3389/fbioe.2022.967475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K22706
[Journal Article] ヒトiPS細胞由来内耳オルガノイドを用いたシスプラチン障害モデルの解析2022
- Author(s)
  栗原渉, 平林源希, 藤岡正人, 細谷誠, 小島博己
- Journal Title
  
  日本耳鼻咽喉科頭頸部外科学会会報
  
  Volume: 125 Pages: 730-730
- Data Source
  KAKENHI-PROJECT-21H04839
[Journal Article] Otic Organoids Containing Spiral Ganglion Neuron-like Cells Derived from Human-induced Pluripotent Stem Cells as a Model of Drug-induced Neuropathy2022
- Author(s)
  Kurihara Sho、Fujioka Masato、Hirabayashi Motoki、Yoshida Tomohiko、Hosoya Makoto、Nagase Masashi、Kato Fusao、Ogawa Kaoru、Okano Hideyuki、Kojima Hiromi、Okano Hirotaka James
- Journal Title
  
  Stem Cells Translational Medicine
  
  Volume: 11 Issue: 3 Pages: 282-296
- DOI
  10.1093/stcltm/szab023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04065, KAKENHI-PROJECT-20K20409, KAKENHI-PROJECT-22K18399, KAKENHI-PROJECT-21H04839
[Journal Article] MRI tractography reveals the human olfactory nerve map connecting the olfactory epithelium and olfactory bulb2022
- Author(s)
  Sho Kurihara, Masayoshi Tei, Junichi Hata, Eri Mori, Masato Fujioka, Yoshinori Matsuwaki, Nobuyoshi Otori, Hiromi Kojima, Hirotaka James Okano
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 843-843
- DOI
  10.1038/s42003-022-03794-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09568, KAKENHI-PROJECT-21H04839, KAKENHI-PROJECT-20H03630, KAKENHI-PROJECT-17K19735
[Journal Article] Author Correction: MRI tractography reveals the human olfactory nerve map connecting the olfactory epithelium and olfactory bulb2022
- Author(s)
  Kurihara Sho、Tei Masayoshi、Hata Junichi、Mori Eri、Fujioka Masato、Matsuwaki Yoshinori、Otori Nobuyoshi、Kojima Hiromi、Okano Hirotaka James
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1219-1219
- DOI
  10.1038/s42003-022-04220-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04839
[Journal Article] Anatomical and Surgical Evaluation of the Common Marmoset as an Animal Model in Hearing Research.2019
- Author(s)
  Kurihara S, Fujioka M, Hata J, Yoshida T, Hirabayashi M, Yamamoto Y, Ogawa K, Kojima H, Okano HJ.
- Journal Title
  
  Frontiers in Neuroanatomy
  
  Volume: 13 Pages: 60-60
- DOI
  10.3389/fnana.2019.00060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-17K10421, KAKENHI-PROJECT-19K21357, KAKENHI-PROJECT-18H04065
[Patent] 再建耳小骨の設計装置、再建耳小骨の設計方法、及び再建耳小骨の設計プログラム2023
- Inventor(s)
  朝倉　巧、伊藤　瑠哉、栗原　渉、平林　源希、倉科　佑太
- Industrial Property Rights Holder
  朝倉　巧、伊藤　瑠哉、栗原　渉、平林　源希、倉科　佑太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-030378
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K22706
[Presentation] ヒトiPS細胞由来内耳オルガノイドを用いた薬剤性難聴モデルの解析2024
- Author(s)
  栗原　渉
- Organizer
  第128回　日本眼科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15896
[Presentation] NUMERICAL SIMULATION OF VIBROACOUSTIC TRANSMISSION CHARACTERISTICS VIA HUMAN MIDDLE EAR2023
- Author(s)
  T. Asakura, T. Ichino, T. Sakurai, R. Ito, Y. Kurashina, M. Hirabayashi, S. Kurihara
- Organizer
  29th International Congress on Sound and Vibration, ICSV 2023 - Prague, Czech Republic
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K22706
[Presentation] Sound transmission through reconstructed middle ear using a full-scale model experiment2023
- Author(s)
  Takuma Ichino, Tomoki Sakurai, Ryuya Ito, Yuta Kurashina, Motoki Hirabayashi, Sho Kurihara and Takumi Asakura
- Organizer
  inter-noise2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K22706
[Presentation] Analysis of interregional connectivity using MRI images of a common marmoset model of hearing loss2022
- Author(s)
  Motoki Hirabayashi,Sho Kurihara, Junichi Hata,Daisuke Yoshimaru,Masato Fujioka,Yutaka Yamamoto, Hiromi Kojimi,Hirotaka James Okano
- Organizer
  Neuro2022-日本神経科学会
- Data Source
  KAKENHI-PROJECT-22K18399
[Presentation] 小型霊長類を用いた音響外傷性難聴モデルの作製とその行動科学的解析2022
- Author(s)
  栗原渉, 平林源希, 新村一, 藤岡正人, 細谷誠, 山本裕, 小島博己
- Organizer
  第32回日本耳科学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] 小型霊長類難聴モデルと超高磁場MRIで明らかにする難聴が及ぼす脳の変化 common marmosetのVBM・VBA解析2022
- Author(s)
  平林源希, 栗原渉, 新村一, 吉村豪兼, 細谷誠, 藤岡正人
- Organizer
  第32回日本耳科学会総会・学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] Analysis of interregional connectivity using MRI images of a common marmoset model of hearing loss2022
- Author(s)
  Motoki Hirabayashi,Sho Kurihara, Junichi Hata,Daisuke Yoshimaru,Masato Fujioka,Yutaka Yamamoto, Hiromi Kojimi,Hirotaka James
- Organizer
  Neuro2022-日本神経科学会
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] 小型霊長類難聴モデルと超高磁場MRIで明らかにする難聴が及ぼす脳の変化 common marmosetのVBM・VBA解析2022
- Author(s)
  平林源希, 栗原渉, 新村一, 吉村豪兼, 細谷誠, 藤岡正人
- Organizer
  第32回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K18399
[Presentation] 小型霊長類を用いた音響外傷性難聴モデルの作製とその行動科学的解析2022
- Author(s)
  栗原渉, 平林源希, 新村一, 藤岡正人, 細谷誠, 山本裕, 小島博己
- Organizer
  第32回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-22K18399
[Presentation] 数値解析を用いた耳小骨再建モデルの伝音特性に関する検討2022
- Author(s)
  一野琢真（東京理科大），平林源希，栗原渉（東京慈恵医大），倉科佑太（東京農工大），朝倉巧（東京理科大）
- Organizer
  騒音制御工学会2022年度秋季研究発表会
- Data Source
  KAKENHI-PROJECT-23K22706
[Presentation] 小型霊長類を用いた音響外傷性難聴モデルの作製とその行動科学的解析2022
- Author(s)
  栗原渉，平林源希，新村一，藤岡正人，細谷誠，山本裕，小島博己
- Organizer
  第32回　日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K18265
[Presentation] 小型霊長類難聴モデルと超高磁場 MRI で明らかにする難聴が及ぼす脳の変化 ― common marmoset の VBM・VBA 解析 ―2022
- Author(s)
  平林源希，栗原渉，新村一，吉村豪兼，細谷誠，藤岡正人
- Organizer
  第32回　日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K18265
[Presentation] Numerical simulation of vibroacoustic transmission characteristics via reconstructed bones of the human middle ear2021
- Author(s)
  T. Asakura, R. Ito, Y. Kurashina, G. Hirabayashi, S. Kurihara
- Organizer
  ICSV 27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 一過性にFT3高値を呈したPendred症候群の一例2021
- Author(s)
  高橋利奈, 栗原勲, 小林佐紀子, 宮下和季, 横田健一, 杉田絵里那, 日鼻瑛, 藤岡正人, 伊藤裕
- Organizer
  第64回日本甲状腺学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] コモンマーモセットの難聴モデルにおける脳Voxel Based Analysisおよび行動解析2021
- Author(s)
  平林源希, 栗原渉, 野武幸子, 力武聖月, 藤岡正人, 山本裕, 小島博己
- Organizer
  日本聴覚医学会
- Data Source
  KAKENHI-PROJECT-20K18265
[Presentation] 数値解析を用いた耳小骨再建モデルの伝音特性に関する検討2021
- Author(s)
  朝倉巧，伊藤瑠哉，倉科佑太，平林源希，栗原渉
- Organizer
  日本音響学会2021年度春季研究発表会
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] コモンマーモセットの難聴モデルにおける脳Voxel Based Analysisおよび行動解析2021
- Author(s)
  平林源希, 栗原渉, 野武幸子, 力武聖月, 藤岡正人, 山本裕, 小島博己
- Organizer
  第66回日本聴覚医学会
- Data Source
  KAKENHI-PROJECT-21H04839
[Presentation] NUMERICAL SIMULATION OF VIBROACOUSTIC TRANSMISSION CHARACTERISTICS VIA RECONSTRUCTED BONES OF HUMAN MIDDLE EAR2021
- Author(s)
  Asakura Takumi*, Ito Ryuya, Aizu Yoshiki, Kurashina Yuta, Hirabayashi Motoki, Kurihara Sho
- Organizer
  ICSV 27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 耳小骨再建モデルの伝音特性に関する検討2020
- Author(s)
  伊藤瑠哉，朝倉巧，倉科佑太，平林源希，栗原渉
- Organizer
  日本音響学会2020年度春季研究発表会
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 耳小骨再建モデルの伝音特性に関する検討2020
- Author(s)
  伊藤瑠哉, 朝倉巧, 倉科佑太, 平林源希, 栗原渉
- Organizer
  Dynamics & Design Conference　2020
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 耳小骨再建モデルの伝音特性に関する有限要素法解析による検討2020
- Author(s)
  平林源希，栗原渉，伊藤瑠哉，山本裕，小島博己，倉科佑太，朝倉巧
- Organizer
  第30回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 耳小骨再建モデルの伝音特性に関する検討2020
- Author(s)
  伊藤瑠哉，朝倉巧，倉科佑太，栗原渉，平林源希
- Organizer
  2020年日本音響学会春季研究発表会
- Data Source
  KAKENHI-PROJECT-19K21949
[Presentation] 小型霊長類コモンマーモセット側頭骨の解剖学的解析による内耳薬剤投与経路の検討2019
- Author(s)
  栗原　渉、藤岡　正人、平林源希、小川　郁、山本　裕、小島　博己
- Organizer
  日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K21357
[Presentation] Visualizing the Olfactory Nerve with Ultra-high Field MRI Tractography2018
- Author(s)
  Masayoshi Tei, Sho Kurihara, Eri Mori, Junichi Hata, Hirotaka James Okano, Nobuyoshi Otori, Hiromi Kojima
- Organizer
  27th Congress of the European Rhinologic Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19735

1. 岡野ジェイムス洋尚 (90338020)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. Tei Masayoshi (50792272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Asakura Takumi (60778207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
4. Fujioka Masato (70398626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. 倉科佑太 (40801535)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. 畑純一 (00568868)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. 岡野栄之 (60160694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. 近藤崇弘 (70759886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 水足邦雄 (40338140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 小島博己 (60234762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. 細谷誠 (30645445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. OGAWA Kaoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KURIHARA Sho 栗原 渉

Kurihara Sho 栗原 渉

Research Projects

Research Products

Co-Researchers

Advancing Novel Therapeutic Approaches for Hearing Loss: Harnessing Human iPSC-Derived Otic Organoids and Innovative Drug Discovery ModalitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a treatment for hearing loss using human iPS cell-derived otic organoids and novel antisense oligosPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrated understanding of the brain network: from auditory perception

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再建中耳を対象としたトポロジー最適化法による伝音難聴治療の方針決定システムの構築

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拡散テンソルイメージングを利用した嗅覚中枢の解明

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Integrated understanding of inner ear disorders and next-generation drug discovery by combination of IoT sensing and iPSC-based medicine

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Functional and structural changes in the brain caused by hearing loss revealed by non-human-primate models and ultra-high field MRIPrincipal Investigator

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Development of an platform for optimization of reconstructed ossicles and its clinical application to ossicular chain reconstruction

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Evaluation of biomarkers connecting the hearing loss and dementia using highly social primate modelPrincipal Investigator

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Visualizing the olfactory map with diffusion tensor imaging: Development of an objective olfactory test method

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[Journal Article] Mechanical effect of reconstructed shapes of autologous ossicles on middle ear acoustic transmission2023

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[Journal Article] ヒトiPS細胞由来内耳オルガノイドを用いたシスプラチン障害モデルの解析2022

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[Journal Article] 小型霊長類コモンマーモセットを用いた聴覚研究2022

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[Journal Article] Combined analysis of finite element model and audiometry provides insights into the pathogenesis of conductive hearing loss2022

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KURIHARA Sho 栗原渉

Kurihara Sho 栗原渉