Noura Mina 能浦三奈

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能浦三奈ノウラミナ

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Researcher Number	90828401
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科(保健), 助教
Affiliation (based on the past Project Information) *help	2023: 名古屋大学, 医学系研究科(保健), 助教 2021: 修文大学, 医療科学部, 助手 2019 – 2020: 天理医療大学, 医療学部, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator KLF4 / 転写因子 / 急性リンパ性白血病 / 腫瘍抑制 / 急性骨髄性白血病 / オートファジー / TXNIP / AML

T細胞性急性リンパ性白血病におけるKLF4の機能解明および新規治療法の開発Principal Investigator
- Principal Investigator
  
  能浦三奈
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Nagoya University
Deciphering the regulatory mechanism of autophagy by TXNIP in acute myeloid leukemia (AML)Principal Investigator
- Principal Investigator
  
  Noura Mina
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shubun University
  Tenri Health Care University

All 2024 2023 2021 2020 2019

All Journal Article Presentation

[Journal Article] Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes2024
- Author(s)
  Matsuo Hidemasa、Inagami Aina、Ito Yuri、Ito Nana、Iyoda Shinju、Harata Yutarou、Higashitani Moe、Shoji Kota、Tanaka Miu、Noura Mina、Mikami Takashi、Kato Itaru、Takita Junko、Nakahata Tatsutoshi、Adachi Souichi
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1 Pages: 123-123
- DOI
  10.1038/s42003-024-05811-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18264, KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-23K07264
[Journal Article] Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia2023
- Author(s)
  Noura Mina、Matsuo Hidemasa、Yasuda Takahiko、Tsuzuki Shinobu、Kiyoi Hitoshi、Hayakawa Fumihiko
- Journal Title
  
  Oncogene
  
  Volume: 43 Issue: 6 Pages: 447-456
- DOI
  10.1038/s41388-023-02913-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08475, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity.2023
- Author(s)
  Kojima Y, Kawashima F, Yasuda T, et al.
- Journal Title
  
  Int J Hematol.
  
  Volume: in press Issue: 1 Pages: 65-74
- DOI
  10.1007/s12185-023-03585-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24362, KAKENHI-PROJECT-23K15298, KAKENHI-PROJECT-22K08490, KAKENHI-PROJECT-21K08384, KAKENHI-PROJECT-21K19505, KAKENHI-PROJECT-23K27624
[Journal Article] Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition2021
- Author(s)
  Tomoo Daifu, Masamitsu Mikami, Hidefumi Hiramatsu, Atsushi Iwai, Katsutsugu Umeda, Mina Noura, Hirohito Kubota, ..., Junko Takita, Hiroshi Sugiyama, Souichi Adachi, Yasuhiko Kamikubo
- Journal Title
  
  Pediatric Blood & Cancer
  
  Volume: 68 Issue: 2
- DOI
  10.1002/pbc.28789
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17875, KAKENHI-PROJECT-20H00528, KAKENHI-PROJECT-21K19405
[Journal Article] Efficacy of a combination therapy targeting CDK4/6 and autophagy in a mouse xenograft model of t(8;21) acute myeloid leukemia2021
- Author(s)
  Matsuo Hidemasa、Nakatani Kana、Harata Yutarou、Higashitani Moe、Ito Yuri、Inagami Aina、Noura Mina、Nakahata Tatsutoshi、Adachi Souichi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 27 Pages: 101099-101099
- DOI
  10.1016/j.bbrep.2021.101099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875
[Journal Article] Albendazole induces the terminal differentiation of acute myeloid leukaemia cells to monocytes by stimulating the Kruppel‐like factor 4‐dihydropyrimidinase‐like 2A (KLF4‐DPYSL2A) axis2021
- Author(s)
  Noura Mina、Morita Ken、Kiyose Hiroki、Okuno Yukiko、Matsuo Hidemasa、Koyama Asami、Nishinaka‐Arai Yoko、Kamikubo Yasuhiko、Adachi Souichi
- Journal Title
  
  British Journal of Haematology
  
  Volume: 194 Issue: 3 Pages: 598-603
- DOI
  10.1111/bjh.17557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875
[Journal Article] TXNIP induces growth arrest and enhances ABT263-induced apoptosis in mixed-lineage leukemia-rearranged acute myeloid leukemia cells.2020
- Author(s)
  Mina Noura, Hidemasa Matsuo, Asami Koyama, Souichi Adachi, Hiroshi Masutani.
- Journal Title
  
  FEBS openbio
  
  Volume: 10 Issue: 8 Pages: 1532-1541
- DOI
  10.1002/2211-5463.12908
- NAID
  120006879474
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07347, KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875
[Journal Article] Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells2020
- Author(s)
  Nakatani Kana、Matsuo Hidemasa、Harata Yutarou、Higashitani Moe、Koyama Asami、Noura Mina、Nishinaka-Arai Yoko、Kamikubo Yasuhiko、Adachi Souichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 113 Issue: 2 Pages: 243-253
- DOI
  10.1007/s12185-020-03015-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875
[Journal Article] Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells2020
- Author(s)
  Noura Mina、Morita Ken、Kiyose Hiroki、Matsuo Hidemasa、Nishinaka-Arai Yoko、Kurokawa Mineo、 Kamikubo Yasuhiko、Adachi Souichi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41598-020-76951-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21538, KAKENHI-PROJECT-19K16832, KAKENHI-PROJECT-19K17875, KAKENHI-PROJECT-18H04052
[Presentation] Suppression of Super-Enhancer-Driven TAL1 Expression By KLF4 in T-Cell Acute Lymphoblastic Leukemia2023
- Author(s)
  能浦三奈、安田貴彦、都築忍、松尾英将、清井仁、早川文彦
- Organizer
  第65回米国血液学会
- Data Source
  KAKENHI-PROJECT-23K15298
[Presentation] T細胞性急性リンパ性白血病においてKLF4はスーパーエンハンサーを介したTAL発現を抑制する2023
- Author(s)
  能浦三奈、早川文彦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K15298
[Presentation] ZNF384融合蛋白転写標的の探索2023
- Author(s)
  山田千晴、岡田健太郎、大平晃也、村木愛実、能浦三奈、岡本修一、安田貴彦、都築忍、早川文彦
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K15298
[Presentation] アルベンダゾールはKLF4-DPYSL2A軸を介して急性骨髄性白血病細胞の単球への分化誘導を促進する2021
- Author(s)
  能浦三奈、森田剣、清瀬大樹、奥野友紀子、松尾英将、小山朝美、西中瑶子、上久保靖彦、足立壯一
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K17875
[Presentation] MLL遺伝子再構成陽性急性骨髄性白血病におけるTXNIPの機能解析2020
- Author(s)
  能浦三奈、松尾英将、小山朝美、足立壯一、増谷弘
- Organizer
  第79回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17875
[Presentation] Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells2019
- Author(s)
  能浦三奈
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17875

1. 松尾英将

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 増谷弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 滝田順子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 黒川峰夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 安田貴彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Noura Mina 能浦 三奈

能浦 三奈 ノウラ ミナ

Research Projects

Research Products

Co-Researchers

T細胞性急性リンパ性白血病におけるKLF4の機能解明および新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering the regulatory mechanism of autophagy by TXNIP in acute myeloid leukemia (AML)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Suppression of malignant rhabdoid tumors through Chb-M'-mediated RUNX1 inhibition2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of a combination therapy targeting CDK4/6 and autophagy in a mouse xenograft model of t(8;21) acute myeloid leukemia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Albendazole induces the terminal differentiation of acute myeloid leukaemia cells to monocytes by stimulating the Kruppel‐like factor 4‐dihydropyrimidinase‐like 2A (KLF4‐DPYSL2A) axis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TXNIP induces growth arrest and enhances ABT263-induced apoptosis in mixed-lineage leukemia-rearranged acute myeloid leukemia cells.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Inhibition of CDK4/6 and autophagy synergistically induces apoptosis in t(8;21) acute myeloid leukemia cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Suppression of Super-Enhancer-Driven TAL1 Expression By KLF4 in T-Cell Acute Lymphoblastic Leukemia2023

Author(s)

Organizer

Data Source

[Presentation] T細胞性急性リンパ性白血病においてKLF4はスーパーエンハンサーを介したTAL発現を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] ZNF384融合蛋白転写標的の探索2023

Author(s)

Organizer

Data Source

[Presentation] アルベンダゾールはKLF4-DPYSL2A軸を介して急性骨髄性白血病細胞の単球への分化誘導を促進する2021

Author(s)

Organizer

Data Source

[Presentation] MLL遺伝子再構成陽性急性骨髄性白血病におけるTXNIPの機能解析2020

Noura Mina 能浦三奈

能浦三奈ノウラミナ