Taniguchi Masayuki 谷口将之

… Alternative Names

Masayuki Taniguchi 谷口将之

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Researcher Number	90831751
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 神戸大学, 医学研究科, 助教 2019 – 2022: 神戸大学, 医学研究科, 特命助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 48030:Pharmacology-related
Keywords	Principal Investigator エピゲノム / ストレス / ミクログリア / 内側前頭前皮質 / 精神疾患 / 神経回路 / シングルセル解析 / 前頭前皮質 / 脳内炎症

ミクログリアの性質変化に着目したストレスによる神経回路異常の解明Principal Investigator
- Principal Investigator
  
  谷口将之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kobe University
Elucidation of machinery for brain homeostasis and its disruption associated with emotional abnormalities by microgliaPrincipal Investigator
- Principal Investigator
  
  Taniguchi Masayuki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kobe University
Elucidation of mechanisms for regulating microglial activation underlying brain microenvironmental deteriorationPrincipal Investigator
- Principal Investigator
  
  Masayuki Taniguchi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen2024
- Author(s)
  Horikawa Io、Nagai Hirotaka、Taniguchi Masayuki、Chen Guowei、Shinohara Masakazu、Suzuki Tomohide、Ishii Shinichi、Katayama Yoshio、Kitaoka Shiho、Furuyashiki Tomoyuki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 154 Issue: 4 Pages: 279-293
- DOI
  10.1016/j.jphs.2024.02.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1560, KAKENHI-PROJECT-18KK0055, KAKENHI-PROJECT-23K06358, KAKENHI-PROJECT-23K06359, KAKENHI-PROJECT-23K07577, KAKENHI-PROJECT-21K06576, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812
[Journal Article] Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4 <sup>+</sup> T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans2024
- Author(s)
  Takeda Shintaro、Emoto Takuo、Yamashita Tomoya、Yamamoto Hiroyuki、Takaya Tomofumi、Sawada Takahiro、Yoshida Takeshi、Inoue Masatoshi、Suzuki Yuya、Hamana Tomoyo、Inoue Taishi、Taniguchi Masayuki、Sasaki Naoto、Otake Hiromasa、Ohkawa Takenao、Furuyashiki Tomoyuki、Kawai Hiroya、Hirata Ken-ichi
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: - Issue: 5 Pages: 1135-1143
- DOI
  10.1161/atvbaha.123.320409
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06359, KAKENHI-PROJECT-22K16105, KAKENHI-PUBLICLY-23H04234, KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-23K27596
[Journal Article] ストレスによる炎症応答における末梢・中枢のクロストーク2024
- Author(s)
  谷口将之，古屋敷智之
- Journal Title
  
  臨床精神医学
  
  Volume: 53 Pages: 443-450
- Data Source
  KAKENHI-PROJECT-23K06359
[Journal Article] Microglial subpopulations with distinct transcriptome signatures vary across brain regions in the resting mouse brain2023
- Author(s)
  Mishima Rei、Taniguchi Masayuki、Matsushita Kazutoshi、Tian Bowen、Furuyashiki Tomoyuki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 3 Pages: 142-147
- DOI
  10.1016/j.jphs.2022.12.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-21K15268, KAKENHI-PLANNED-18H05429
[Journal Article] N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling2023
- Author(s)
  Sakai Mai、Yu Zhiqian、Taniguchi Masayuki、Picotin Rosanne、Oyama Nanami、Stellwagen David、Ono Chiaki、Kikuchi Yoshie、Matsui Ko、Nakanishi Miharu、Yoshii Hatsumi、Furuyashiki Tomoyuki、Abe Takaaki、Tomita Hiroaki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3798-3798
- DOI
  10.3390/ijms24043798
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04812, KAKENHI-PROJECT-20K07962, KAKENHI-PROJECT-21K15268, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-22K15742
[Journal Article] Single-Cell RNA Sequencing Reveals a Distinct Immune Landscape of Myeloid Cells in Coronary Culprit Plaques Causing Acute Coronary Syndrome2022
- Author(s)
  Emoto Takuo、Yamamoto Hiroyuki、Yamashita Tomoya、Takaya Tomofumi、Sawada Takahiro、Takeda Shintaro、Taniguchi Masayuki、Sasaki Naoto、Yoshida Naofumi、Saito Yoshihiro、Sivasubramaniyam Tharini、Otake Hiromasa、Furuyashiki Tomoyuki、Robbins Clinton S.、Kawai Hiroya、Hirata Ken-ichi
- Journal Title
  
  Circulation
  
  Volume: 145 Issue: 18 Pages: 1434-1436
- DOI
  10.1161/circulationaha.121.058414
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17152, KAKENHI-PROJECT-21K15268, KAKENHI-PROJECT-21H04812, KAKENHI-PLANNED-18H05429
[Journal Article] Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice2021
- Author(s)
  Uchida Mizuki、Noda Yukihiro、Hasegawa Sho、Hida Hirotake、Taniguchi Masayuki、Mouri Akihiro、Yoshimi Akira、Nabeshima Toshitaka、Yamada Kiyofumi、Aida Tomomi、Tanaka Kohichi、Ozaki Norio
- Journal Title
  
  Neurochemistry International
  
  Volume: 150 Pages: 105177-105177
- DOI
  10.1016/j.neuint.2021.105177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04252, KAKENHI-PROJECT-20K07931, KAKENHI-PROJECT-21K06719, KAKENHI-PROJECT-21K15268, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21H04815
[Journal Article] ocial defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex2019
- Author(s)
  Numa Chisato, Nagai Hirotaka, Taniguchi Masayuki, Nagai Midori, Shinohara Ryota, Furuyashiki Tomoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 16670-16670
- DOI
  10.1038/s41598-019-52997-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15028, KAKENHI-PROJECT-19K16372, KAKENHI-PLANNED-18H05429, KAKENHI-PROJECT-16H06276
[Presentation] マウスの慢性ストレスによる骨髄・脾臓での遺伝子発現・細胞組成・脂質メディエーターの変化2024
- Author(s)
  堀川伊和, 永井裕崇, 谷口将之, 陳国威, 篠原正和, 鈴木知秀, 石井慎一, 片山義雄, 北岡志保, 古屋敷智之
- Organizer
  第144回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K06359
[Presentation] ミクログリアはストレスによる複数の分子経路を統合し認知情動変容を誘導する2024
- Author(s)
  谷口将之，古屋敷智之
- Organizer
  第8回日本骨免疫学会ウインタースクール
- Data Source
  KAKENHI-PROJECT-23K06359
[Presentation] ストレスによるミクログリアの転写・エピゲノム応答とその役割2023
- Author(s)
  谷口将之
- Organizer
  第147回日本薬理学会関東部会次世代薬理学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] ミクログリアはToll様受容体2/4とグルココルチコイド受容体を介してストレス期間とストレス感受性を統合し情動変容を誘導する2023
- Author(s)
  谷口将之, 松下和敏, 三島零, 北岡志保, 工樂樹洋, 門田満隆, 古屋敷智之
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K06359
[Presentation] マウスの慢性社会挫折ストレスによる情動行動変化とミクログリア活性化におけるP2X7受容体の役割2023
- Author(s)
  田博文, 谷口将之, 松下和敏, 三島零, 谷津健太, 古屋敷智之
- Organizer
  第143回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-23K06359
[Presentation] ストレスによるミクログリアの転写・エピゲノム応答とその役割2023
- Author(s)
  谷口将之, 古屋敷智之
- Organizer
  第44回日本炎症再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06359
[Presentation] Transcriptional and epigenetic regulations of microglia for stress responses2022
- Author(s)
  Taniguchi M, Matsushita K, Mishima R, Kitaoka S, Kuraku S, Kadota M, Furuyashiki T
- Organizer
  NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] Chronic social stress-induced transition of microglial transcriptome states in mice2022
- Author(s)
  Mishima R, Taniguchi M, Matsushita K, Furuyashiki T
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] Stress-induced transcriptional and epigenetic landscape of microglia2022
- Author(s)
  谷口将之、古屋敷智之
- Organizer
  BPCNPNPPP4学会合同年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 脳と末梢のストレス応答を統合するミクログリアの転写プログラム2022
- Author(s)
  谷口将之，古屋敷智之
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 慢性ストレスへのミクログリア応答の半球非対称性2022
- Author(s)
  松下和敏, 谷口将之, 古屋敷智之
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] Transcriptional machinery of microglial stress response2022
- Author(s)
  Taniguchi M, Furuyashiki T
- Organizer
  第96回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] Hemispheric asymmetry in chronic stress-induced microglial responses2022
- Author(s)
  Matsushita K, Taniguchi M, Furuyashiki T
- Organizer
  NEURO 2022
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 社会ストレスによるミクログリアのエピゲノム制御における多様な時空間的パターン2021
- Author(s)
  谷口将之、松下和敏、三島零、北岡志保、工樂樹洋、門田満隆、古屋敷智之
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16372
[Presentation] ミクログリアのストレス応答を担う転写・エピゲノム制御2021
- Author(s)
  谷口将之, 松下和敏, 三島零, 北岡志保, 工樂樹洋, 門田満隆, 古屋敷智之
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 一細胞解析による内側前頭前皮質のミクログリアのサブタイプとストレス応答性の多様性2021
- Author(s)
  三島零，谷口将之，松下和敏，古屋敷智之
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 慢性ストレスへのミクログリア応答の左右非対称性2021
- Author(s)
  松下和敏, 谷口将之, 古屋敷智之
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] ミクログリアの局所的および全般的なストレス応答を担う転写・エピゲノム制御2021
- Author(s)
  谷口将之, 松下和敏, 三島零, 北岡志保, 工樂樹洋, 門田満隆, 古屋敷智之
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K15268
[Presentation] 社会挫折ストレスにより誘導される内側前頭前皮質ミクログリアのエピゲノム変化の解析2020
- Author(s)
  谷口　将之
- Organizer
  シグナル伝達医学研究展開センター(CSMI)主催若手研究者リトリート「若手道場」
- Data Source
  KAKENHI-PROJECT-19K16372
[Presentation] Chronic Stress-Induced Epigenetic Changes of Microglia2020
- Author(s)
  Masayuki Taniguchi, Kazutoshi Matsushita, Mitsutaka Kadota, Shigehiro Kuraku, Tomoyuki Furuyashiki
- Organizer
  ACNP 2020 米国精神神経医学会議 American College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16372
[Presentation] 反復社会挫折ストレスによる内側前頭前皮質ミクログリアのエピゲノム制御2020
- Author(s)
  谷口将之、北岡志保、工樂樹洋、門田満隆、古屋敷智之
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16372
[Presentation] Analysis of epigenetic changes in prefrontal microglia induced by repeated social defeat stress2019
- Author(s)
  Masayuki Taniguchi, Shiho Kitaoka, Shigehiro Kuraku, Mitsutaka Kadota, Tomoyuki Furuyashiki
- Organizer
  University of Washington Department of Pharmacology 2019 Symposium on Molecular Pharmacology
- Data Source
  KAKENHI-PROJECT-19K16372

1. MOURI Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. FURUYASHIKI Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 鍋島俊隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 江本拓央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 永井裕崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taniguchi Masayuki 谷口 将之

Masayuki Taniguchi 谷口 将之

Research Projects

Research Products

Co-Researchers

ミクログリアの性質変化に着目したストレスによる神経回路異常の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of machinery for brain homeostasis and its disruption associated with emotional abnormalities by microgliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of mechanisms for regulating microglial activation underlying brain microenvironmental deteriorationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Chronic stress alters lipid mediator profiles associated with immune-related gene expressions and cell compositions in mouse bone marrow and spleen2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-Cell RNA Sequencing Reveals an Immune Landscape of CD4 <sup>+</sup> T Cells in Coronary Culprit Plaques With Acute Coronary Syndrome in Humans2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ストレスによる炎症応答における末梢・中枢のクロストーク2024

Author(s)

Journal Title

Data Source

[Journal Article] Microglial subpopulations with distinct transcriptome signatures vary across brain regions in the resting mouse brain2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-Acetylcysteine Suppresses Microglial Inflammation and Induces Mortality Dose-Dependently via Tumor Necrosis Factor-α Signaling2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-Cell RNA Sequencing Reveals a Distinct Immune Landscape of Myeloid Cells in Coronary Culprit Plaques Causing Acute Coronary Syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ocial defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] マウスの慢性ストレスによる骨髄・脾臓での遺伝子発現・細胞組成・脂質メディエーターの変化2024

Author(s)

Organizer

Data Source

[Presentation] ミクログリアはストレスによる複数の分子経路を統合し認知情動変容を誘導する2024

Author(s)

Organizer

Data Source

[Presentation] ストレスによるミクログリアの転写・ エピゲノム応答とその役割2023

Author(s)

Organizer

Data Source

[Presentation] ミクログリアはToll様受容体2/4とグルココルチコイド受容体を介してストレス期間とストレス感受性を統合し情動変容を誘導する2023

Author(s)

Organizer

Data Source

[Presentation] マウスの慢性社会挫折ストレスによる情動行動変化とミクログリア活性化におけるP2X7受容体の役割2023

Author(s)

Taniguchi Masayuki 谷口将之

Masayuki Taniguchi 谷口将之

[Presentation] ストレスによるミクログリアの転写・エピゲノム応答とその役割2023