Tochinai Ryota 栃内亮太

Researcher Number	90833997
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 大学院農学生命科学研究科(農学部), 助教 2020 – 2023: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related Except Principal Investigator Medium-sized Section 64:Environmental conservation measure and related fields / Medium-sized Section 38:Agricultural chemistry and related fields / Basic Section 53020:Cardiology-related / Medium-sized Section 51:Brain sciences and related fields / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields / Basic Section 55060:Emergency medicine-related / Medium-sized Section 42:Veterinary medical science, animal science, and related fields
Keywords	Principal Investigator パルスオキシメーター / ウエアラブルデバイス / ラット / 脈波 / BET family タンパク / 微小管 / combretastatin A4 / JQ1 / microtubule / BRD4 / 心毒性 / 抗がん剤 … More Except Principal Investigator … More 毒性評価技術 / マルチモーダルバイタルサイン / ウェアラブルデバイス / 毒性試験 / iPS / 筋ジストロフィー / 心機能 / 骨格筋 / 心筋 / ケトン食 / 中鎖トリグリセリド / モデル動物 / デュシェンヌ型筋ジストロフィー / 組織幹細胞 / 遅発性心毒性 / 自律神経 / 遅発性 / 不整脈 / 高血圧 / ドキソルビシン / 心毒性 / 抗がん剤 / 抑制性介在性神経細胞 / SIDS / 抑制性介在神経 / 妊娠 / 孤束核 / グリシン / GABA / 副流煙 / 乳幼児突然死 / スマートデバイス / 電子システム / ハイドロゲル / 液体金属 / 神経原性肺水腫 / グリコカリックス / 神経原性肺水 / くも膜下出血 / アルブミン感作 / ヒスタミンH３受容体 / 三叉神経核 / 三叉神経脊髄路核尾側亜核　鼻粘膜　免疫染色 / 鼻アレルギー / くしゃみ / H3受容体 / ヒスタミン / アストロサイト / 免疫染色 / 鼻粘膜 / 三叉神経脊髄路核尾側亜核 Less

動物死を回避する化学物質の新規 in vivo 安全性評価法の開発Principal Investigator
- Principal Investigator
  
  栃内亮太
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
新規ウエアラブルデバイスによる小型実験動物の脈波伝播時間の解析技術開発Principal Investigator
- Principal Investigator
  
  栃内亮太
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
DXによるin vivo毒性評価技術の発展的継承と一般化
- Principal Investigator
  
  大久保佑亮
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  National Institute of Health Sciences
Glycocalyxの機能に着目した神経原性肺水腫の病態解明と重症化回避への挑戦
- Principal Investigator
  
  武藤達士
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Akita Cerebrospinal and Cardiovascular Center
ハイドロゲルと液体金属から構成される超ソフト電子機械システムに関する研究
- Principal Investigator
  
  太田裕貴
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
- Research Institution
  Yokohama National University
Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?
- Principal Investigator
  
  関澤信一
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  The University of Tokyo
Development of innovative muscular dystrophy treatment with a novel ketogenic diet
- Principal Investigator
  
  大石勝隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Research on novel therapeutic targets for nasal allergy
- Principal Investigator
  
  関澤信一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
Development of BRD4 inhibitor combination therapy for suppressing cardiotoxicity of anticancer drugsPrincipal Investigator
- Principal Investigator
  
  Tochinai Ryota
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  The University of Tokyo
athogenesis of delayed cardiotoxicity of anticancer drugs focusing on the autonomic nervous system and its stem cells
- Principal Investigator
  
  Masayoshi Kuwahara
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Cardiopulmonary Events of the Elderly during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan2024
- Author(s)
  Tatsushi Mutoh, Hiroaki Aono, Wataru Seto, Takehiro Kimoto, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa
- Journal Title
  
  Medicina
  
  Volume: 60 Issue: 1 Pages: 185-185
- DOI
  10.3390/medicina60010185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09110
[Journal Article] Factors Influencing Discontinuation of Clazosentan Therapy in Elderly Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study from a Japanese Single Center2024
- Author(s)
  Tatsushi Mutoh, Hiroaki Aono, Wataru Seto, Takehiro Kimoto, Ryota Tochinai, Junta Moroi, Tatsuya Ishikawa
- Journal Title
  
  Med Sci Monit
  
  Volume: 30
- DOI
  10.12659/msm.943303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09110
[Journal Article] Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat2024
- Author(s)
  Tochinai Ryota、Kimura Koichi、Saika Takeru、Fujii Wataru、Morita Hiroyuki、Nakanishi Koki、Tsuru Yoshiharu、Sekizawa Shin-ichi、Yamanouchi Keitaro、Kuwahara Masayoshi
- Journal Title
  
  Exp. Anim.
  
  Volume: 73 Issue: 2 Pages: 145-153
- DOI
  10.1538/expanim.23-0087
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18345, KAKENHI-PROJECT-23K06905
[Journal Article] Simple procedure for assessing diffuse subarachnoid hemorrhage successfully created using filament perforation method in mice2023
- Author(s)
  Mutoh Tatsushi、Tochinai Ryota、Aono Hiroaki、Kuwahara Masayoshi、Taki Yasuyuki、Ishikawa Tatsuya
- Journal Title
  
  Animal Models and Experimental Medicine
  
  Volume: 7 Issue: 1 Pages: 77-81
- DOI
  10.1002/ame2.12372
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09110
[Journal Article] Direct Wiring of Liquid Metal on an Ultrasoft Substrate Using a Polyvinyl Alcohol Lift-off Method2022
- Author(s)
  Murakami Koki、Tochinai Ryota、Tachibana Daiki、Isano Yuji、Matsuda Ryosuke、Nakamura Fumika、Kurotaki Yuta、Isoda Yutaka、Yamane Monami、Sugita Yuya、Fukuda Junji、Ueno Kazuhide、Miki Norihisa、Fuchiwaki Ohmi、Ota Hiroki
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 14 Issue: 5 Pages: 7241-7251
- DOI
  10.1021/acsami.1c20628
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20H05744, KAKENHI-PROJECT-22K18288
[Presentation] Development of a wearable device used to monitor multimodal vital signs in conscious, unrestrained rats2024
- Author(s)
  Okubo Y., Kojima S., Ohara I., Min M., Taquahashi Y., Tochinai R. Ota H.
- Organizer
  Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17469
[Presentation] EARLY LOW-DOSE NOREPINEPHRINE PROTECTS AGAINST POST-CPR NEUROGENIC INJURY AFTER EXPERIMENTAL SAH2024
- Author(s)
  Mutoh T; Tochinai R; Sasaki K; Aono H; Junta M; Kuwahara M; Ishikawa T
- Organizer
  2024 Critical Care Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09110
[Presentation] H3 Receptor Expression in the Spinal Trigeminal Nucleus Caudalis in a Rat Model of Allergic Rhinitis2024
- Author(s)
  Airi Tanaka, Hu Cong, Shin-ichi Sekizawa, Ryota Tochinai, Masayosi Kuwahara
- Organizer
  American Physiological Society Summit 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19182
[Presentation] 覚醒化非拘束ラット用マルチバイタル・活動量測定ウェアブルデバイスの開発2023
- Author(s)
  小島　竣平、小原　息吹、高野　珠実、磯田　豊，馬　敏、栃内　亮太、大久保　佑亮、高橋　祐次、太田　裕貴
- Organizer
  第50回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K17469
[Presentation] Ivabradine treatment for cardiomyopathy with autonomic nervous system disorder in a CRISPR/Cas9 gene-edited Duchenne muscular dystrophy model rat.2023
- Author(s)
  Tochinai R, Kimura K, Saika T, Miyamoto M, Shiga T, Fujii W, Tsuru Y, Sekizawa SI, Yamanouchi K, Kuwahara M
- Organizer
  Bilateral Symposium between Taiwan and Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18345
[Presentation] CRISPR/Cas9筋ジストロフィーモデルラットにウエアラブルデバイス技術を応用した心筋症の病態と新治療研究2022
- Author(s)
  栃内亮太、雑賀彪、小島竣平、木村公一、宮本真緒、水流功春、関澤信一、大久保佑亮、太田裕貴、山内啓太郎、桑原正貴
- Organizer
  第69回　日本実験動物学会
- Data Source
  KAKENHI-PROJECT-22K18345
[Presentation] 微小管重合阻害薬とBRD4阻害薬の併用による新規がん化学療法の開発2022
- Author(s)
  折原遥香、加藤大貴、関澤信一、武藤達士、瀧靖之、品田真央、青木督、藤田直己、中川貴之、西村亮平、桑原正貴、○栃内亮太
- Organizer
  第25回日本獣医がん学会
- Data Source
  KAKENHI-PROJECT-20K15676

1. 関澤信一 (80760420)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. Masayoshi Kuwahara (30205273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 太田裕貴 (30528435)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 大久保佑亮 (80596247)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 武藤達士 (80462472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. 竹村泰司 (30251763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大石勝隆 (50338688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 木村公一 (50596236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 山内啓太郎 (70272440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 藤倉祐里 (50849974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 福田淳二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tochinai Ryota 栃内 亮太

Research Projects

Research Products

Co-Researchers

動物死を回避する化学物質の新規 in vivo 安全性評価法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規ウエアラブルデバイスによる小型実験動物の脈波伝播時間の解析技術開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DXによるin vivo毒性評価技術の発展的継承と一般化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Glycocalyxの機能に着目した神経原性肺水腫の病態解明と重症化回避への挑戦

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ハイドロゲルと液体金属から構成される超ソフト電子機械システムに関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Are changes in the properties of nucleus tractus solitarius inhibitory interneurons during postnatal development a risk factor for sudden infant death syndrome?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative muscular dystrophy treatment with a novel ketogenic diet

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on novel therapeutic targets for nasal allergy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of BRD4 inhibitor combination therapy for suppressing cardiotoxicity of anticancer drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

athogenesis of delayed cardiotoxicity of anticancer drugs focusing on the autonomic nervous system and its stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Cardiopulmonary Events of the Elderly during Clazosentan Therapy after Subarachnoid Hemorrhage: A Retrospective Study from a Tertiary Stroke Center in Japan2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Factors Influencing Discontinuation of Clazosentan Therapy in Elderly Patients with Aneurysmal Subarachnoid Hemorrhage: A Retrospective Study from a Japanese Single Center2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ivabradine ameliorates cardiomyopathy progression in a Duchenne muscular dystrophy model rat2024

Author(s)

Journal Title

DOI

ISSN

Language

Tochinai Ryota 栃内亮太