Kobayashi Sohei 小林崇平

Researcher Number	90846940
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, 成田保健医療学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 国際医療福祉大学, 成田保健医療学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 抗体医薬品 / 臨床検査 / 悪性腫瘍 / 分子標的マーカー / 抗がん剤開発 / 新規動態解析 / mTORシグナリング経路 Except Principal Investigator FIR/PUF60 / リボソーム / rRNA … More / mRNA / 癌化機構 / 転写 / ribosomal RNA / RNA polymerase II / 核小体 / ドミナントネガティブ / スプライシング変異 / c-Myc / 転写後調節 / がん治療 / がん診断 / スプライシング / ヒストンアセチル化 / TFIIH p62 subunit / リボソーマルRNA / TFIIH / RNA-Seq / FIR / 疾患バイオマーカー候補 / 網羅的ゲノム解析 / 希少疾患 / 癌 / NGS / 質量分析 / バイオマーカー / 発現亢進 / がん Less

mTORシグナリング経路の新規動態解析と関連する抗がん剤開発Principal Investigator
- Principal Investigator
  
  小林崇平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  International University of Health and Welfare
核小体内におけるRNA polymerase IIによるribosomal RNAの転写と癌化機構の解明
- Principal Investigator
  
  松下一之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Expression analysis of ribosome constituent proteins in cancer cells and their involvement in post-transcriptional regulation
- Principal Investigator
  
  Matsushita Kazuyuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Chiba University
The significance of the novel molecular target FIRdeltaexon2 as a companion marker and the mechanism of its expression.Principal Investigator
- Principal Investigator
  
  Kobayashi Sohei
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  International University of Health and Welfare

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer2023
- Author(s)
  Kitamura Kouichi、Hoshino Tyuji、Okabe Atsushi、Fukuyo Masaki、Rahmutulla Bahityar、Tanaka Nobuko、Kobayashi Sohei、Tanaka Tomoaki、Shida Takashi、Ueda Mashiro、Minamoto Toshinari、Matsubara Hisahiro、Kaneda Atsushi、Ishii Hideshi、Matsushita Kazuyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 24 Pages: 17341-17341
- DOI
  10.3390/ijms242417341
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17429, KAKENHI-PROJECT-21K15599, KAKENHI-PROJECT-19KK0415, KAKENHI-PROJECT-22K07164, KAKENHI-PROJECT-23K06618, KAKENHI-PROJECT-23K06712, KAKENHI-PROJECT-20K07336, KAKENHI-PROJECT-21K19526, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00541, KAKENHI-PROJECT-23K23859
[Journal Article] Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels2023
- Author(s)
  Arasawa Takahiro、Hiwasa Takaki、Kagaya Akiko、Maruyama Tetsuro、Uesato Masaya、Kano Masayuki、Kobayashi Sohei、Takizawa Hirotaka、Iwase Katsuro、Nomura Fumio、Matsushita Kazuyuki、Matsubara Hisahiro
- Journal Title
  
  BMC Cancer
  
  Volume: 23 Issue: 1 Pages: 356-356
- DOI
  10.1186/s12885-023-10845-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-22K08747, KAKENHI-PROJECT-23K06618
[Journal Article] Combinational antibody detection approach increases the clinical validity of colorectal cancer screening2023
- Author(s)
  Kobayashi Sohei、Hiwasa Takaki、Kitamura Kouichi、Kano Masayuki、Hoshino Tyuji、Hirano Sho、Hashimoto Mayuko、Seimiya Masanori、Shimada Hideaki、Nomura Fumio、Matsubara Hisahiro、Matsushita Kazuyuki
- Journal Title
  
  Journal of Clinical Laboratory Analysis
  
  Volume: 37 Issue: 21-22 Pages: 1-11
- DOI
  10.1002/jcla.24978
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07858, KAKENHI-PROJECT-21K08695, KAKENHI-PROJECT-22K08747, KAKENHI-PROJECT-23K06618, KAKENHI-PROJECT-23K06712, KAKENHI-PROJECT-20K07336
[Journal Article] Metformin-Induced Heat Shock Protein Family A Member 6 Is a Promising Biomarker of Esophageal Squamous Cell Carcinoma2022
- Author(s)
  Nobufumi Sekino、Sohei Kobayashi、Hisahiro Matsubara
- Journal Title
  
  Oncology
  
  Volume: 100 Issue: 5 Pages: 267-277
- DOI
  10.1159/000522446
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-22K08747, KAKENHI-PROJECT-20H03749
[Journal Article] Anti-FIRΔexon2 autoantibody as a novel indicator for better overall survival in gastric cancer2021
- Author(s)
  Kobayashi S, Hiwasa T, Ishige T, Kano M, Hoshino T, Rahmutulla B, Seimiya M, Shimada H, Nomura F, Matsubara H, Matsushita K.
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 847-858
- DOI
  10.1111/cas.14767
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07336, KAKENHI-PROJECT-20K07858, KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-20K16513
[Journal Article] Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke.2021
- Author(s)
  Hiwasa T, Wang H, Iwadate Y. et al
- Journal Title
  
  BMC Med
  
  Volume: 19 Issue: 1 Pages: 131-131
- DOI
  10.1186/s12916-021-02001-9
- NAID
  120007132378
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-19H03664, KAKENHI-PROJECT-20H03449, KAKENHI-PROJECT-19K08596, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K16436
[Journal Article] Serum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis2021
- Author(s)
  Li Shu-Yang、Sohei Kobayashi、Takaki Hiwasa
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 13450-13450
- DOI
  10.1038/s41598-021-92786-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-20K17953
[Journal Article] Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer2020
- Author(s)
  Ailiken Guzhanuer、Kitamura Kouichi、Hoshino Tyuji、Satoh Mamoru、Tanaka Nobuko、Minamoto Toshinari、Rahmutulla Bahityar、Kobayashi Sohei、Kano Masayuki、Tanaka Tomoaki、Kaneda Atsushi、Nomura Fumio、Matsubara Hisahiro、Matsushita Kazuyuki
- Journal Title
  
  Oncogenesis
  
  Volume: 9 Issue: 2 Pages: 26-26
- DOI
  10.1038/s41389-020-0205-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-17KT0124, KAKENHI-PROJECT-18K07462, KAKENHI-PROJECT-20K07336, KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-19H03708, KAKENHI-PROJECT-17K09004, KAKENHI-PROJECT-18K19577
[Journal Article] Serum anti-LRPAP 1 is a common biomarker for digestive organ cancers and atherosclerotic diseases2020
- Author(s)
  Sumazaki M, Shimada H, Ito M, Shiratori F, Iwadate Y, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 12 Pages: 4453-4464
- DOI
  10.1111/cas.14652
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K08445, KAKENHI-PROJECT-20K21523, KAKENHI-PROJECT-17K16626, KAKENHI-PROJECT-20K16436, KAKENHI-PROJECT-20K17953, KAKENHI-PROJECT-20H03449
[Presentation] 光がビリルビン測定値に与える影響2023
- Author(s)
  清宮正徳 , 安達愛香 , 金子葵 , 北野萌子 , 平井佑芽 , 米根鉄矢 , 小林崇平 , 松下一之
- Organizer
  生物試料分析科学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 乳びや蛋白質濃度が電解質測定値に与える影響2023
- Author(s)
  清宮正徳 , 鈴木友乃 , 伝福友加 , 米根鉄矢 , 小林崇平 , 松下一之
- Organizer
  生物試料分析科学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 肝臓癌の発症・進展機序の解明2023
- Author(s)
  堀井雪乃, 小林崇平, 志田隆史, 佐藤智明, 松下一之, 清宮正徳
- Organizer
  医療検査と自動化(Web) 48(4) 2023年
- Data Source
  KAKENHI-PROJECT-23K06618
[Presentation] 膵臓癌における抗FIRΔexon2自己抗体のバイオマーカーとしての検討2023
- Author(s)
  高橋龍治, 平野翔, 小林崇平, 清宮正徳, 佐藤智明, 松下一之
- Organizer
  日本遺伝子診療学会大会プログラム・抄録集 30th 2023年
- Data Source
  KAKENHI-PROJECT-23K06618
[Presentation] 膵臓癌における抗FIRΔexon2自己抗体のバイオマーカーとしての検討2023
- Author(s)
  高橋龍治, 平野翔, 小林崇平, 清宮正徳, 佐藤智明, 松下一之, 高橋龍治, 平野翔, 小林崇平, 松下一之
- Organizer
  第30回日本遺伝子診療学会大会
- Data Source
  KAKENHI-PROJECT-20K07336
[Presentation] 肝疾患メカニズムによる腫瘍免疫監視機構因子MICBの有用性2022
- Author(s)
  菅谷陸、小林崇平、大星航、川崎健治、松下一之、長沢光章、清宮正徳
- Organizer
  第31・32回生物試料分析科学会合同学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 肝細胞癌診断のための血清中抗CHC抗体測定法の検討2022
- Author(s)
  清宮正徳 , 岡村澪 , 松永結夏 , 小林崇平 , 松下一之
- Organizer
  生物試料分析科学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 国内患者集団におけるミスマッチ修復欠損胆道癌の免疫組織学的特徴と予測因子についての検討2022
- Author(s)
  須田竜一郎 , 須田竜一郎 , 酒井望 , 松下一之 , 石毛崇之 , 小林崇平 , 川崎洋平 , 仕子優樹 , 古川勝規 , 三島敬 , 中台英里 , 海保隆 , 大塚将之
- Organizer
  日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 癌抑制因子FIRのスプライシング変異体FIRΔexon2に対する自己抗体は胃癌の生存率を改善するための新しい指標2021
- Author(s)
  小林崇平、志田隆史、竹内啓晃、長沢光章、三宅克也、清宮正徳
- Organizer
  第11回国際医療福祉大学学会学術大会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 肝臓癌細胞株における癌抑制因子FIRとFIRスプライシング変異体FIRΔexon2の機能解析2021
- Author(s)
  平野翔、小林崇平、松下一之、清宮正徳
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K16436
[Presentation] 癌抑制因子FIRは肝臓癌細胞株の細胞増殖に関与する2021
- Author(s)
  橋本真由子、小林崇平、亀田朋希、後藤陽登、平野翔、宮嶋亮弥、志田隆史、大星航、松下一之、清宮正徳
- Organizer
  第15回日本臨床検査学教育学会
- Data Source
  KAKENHI-PROJECT-20K16436

1. Matsushita Kazuyuki (90344994)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. 星野忠次 (90257220)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 石毛崇之 (30757315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 西村基 (80400969)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 北村浩一 (90842881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 澤井摂 (10400962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 木村明佐子 (40727939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SEIMIYA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. IWADATE Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Sohei 小林 崇平

Research Projects

Research Products

Co-Researchers

mTORシグナリング経路の新規動態解析と関連する抗がん剤開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

核小体内におけるRNA polymerase IIによるribosomal RNAの転写と癌化機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression analysis of ribosome constituent proteins in cancer cells and their involvement in post-transcriptional regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The significance of the novel molecular target FIRdeltaexon2 as a companion marker and the mechanism of its expression.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Link of mRNA and rRNA Transcription by PUF60/FIR through TFIIH/P62 as a Novel Therapeutic Target for Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combinational antibody detection approach increases the clinical validity of colorectal cancer screening2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metformin-Induced Heat Shock Protein Family A Member 6 Is a Promising Biomarker of Esophageal Squamous Cell Carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-FIRΔexon2 autoantibody as a novel indicator for better overall survival in gastric cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum anti-DIDO1, anti-CPSF2, and anti-FOXJ2 antibodies as predictive risk markers for acute ischemic stroke.2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Serum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum anti-LRPAP 1 is a common biomarker for digestive organ cancers and atherosclerotic diseases2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 光がビリルビン測定値に与える影響2023

Author(s)

Organizer

Data Source

[Presentation] 乳びや蛋白質濃度が電解質測定値に与える影響2023

Author(s)

Kobayashi Sohei 小林崇平