IGUCHI TOMOKI 井口巴樹

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Iguchi Tomoki 井口巴樹

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Researcher Number	90847120
Other IDs	https://orcid.org/0000-0003-0337-9776
Affiliation (Current)	2024: 東京薬科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京薬科大学, 薬学部, 助教 2019 – 2020: 東京薬科大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / 0801:Pharmaceutical sciences and related fields Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords	Principal Investigator 天然物 / アポトーシス / ステロイド配糖体 / がん / サポニン / 非内因性経路 / 小細胞肺がん / トリテルペン配糖体 / 腫瘍細胞 / ミトコンドリア / ミトコンドリア非依存的 … More Except Principal Investigator … More 併用効果 / 特定外来植物 / 天然物 / 抗がん剤 / PARP阻害薬シーズ Less

Search for new seeds of anti-cancer agents targeting PARP from natural products
- Principal Investigator
  
  三巻祥浩
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
非内因性経路に着目した植物由来サポニンのアポトーシス誘導メカニズムの解明Principal Investigator
- Principal Investigator
  
  井口巴樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucidation of induction of apoptosis by steroidal glycosides via a mitochondria-independent pathwayPrincipal Investigator
- Principal Investigator
  
  Iguchi Tomoki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Structure elucidation of 16 undescribed steroidal glycosides from the underground parts of Agapanthus africanus and apoptosis-inducing activity in small-cell lung cancer cell2023
- Author(s)
  Takahashi N., Iguchi T., Nagamine A., Shirai R., Nagata A., Yamauchi J., Mimaki Y.
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 2 Pages: 2808-2830
- DOI
  10.1021/acsomega.2c07766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15306
[Journal Article] Novel Oleanane-Type Triterpene Glycosides from the Saponaria officinalis L. Seeds and Apoptosis-Inducing Activity via Mitochondria2022
- Author(s)
  Takahashi N., Iguchi T., Kuroda M., Mishima M., Mimaki Y.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 23 Issue: 4 Pages: 2047-2047
- DOI
  10.3390/ijms23042047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15306
[Journal Article] Phenolic compounds from the underground parts of Eremurus robustus and their cytotoxicity2022
- Author(s)
  Iguchi T., Kuroda M., Morita H., Mimaki Y.
- Journal Title
  
  Jpn. J. Pharmacog.
  
  Volume: 76 Pages: 45-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15306
[Journal Article] Three novel furospirostanol glycosides and a steroidal alkaloid glycoside from the bulbs of Fritillaria camtschatcensis (L.) Ker Gawl., and their cytotoxicity2021
- Author(s)
  Iguchi Tomoki、Kuroda Minpei、Takayama Hiroshi、Mimaki Yoshihiro
- Journal Title
  
  Natural Product Research
  
  Volume: - Issue: 15 Pages: 1-7
- DOI
  10.1080/14786419.2021.1897590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23809
[Journal Article] A Total of Eight Novel Steroidal Glycosides Based on Spirostan, Furostan, Pseudofurostan, and Cholestane from the Leaves of Cestrum newellii2020
- Author(s)
  Iguchi Tomoki、Takahashi Naoki、Mimaki Yoshihiro
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 19 Pages: 4462-4475
- DOI
  10.3390/molecules25194462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23809
[Presentation] ユリ科 Agapanthus africanus 地下部から単離された新規ステロイド配糖体の構造と SBC-3 ヒト小細胞肺がん細胞に対するアポトーシス誘導活性2022
- Author(s)
  高橋直熙，井口巴樹，永峯杏樹，横須賀章人，三巻祥浩
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-22K15306

1. 三巻祥浩 (90229790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 松尾侑希子 (70434016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IGUCHI TOMOKI 井口 巴樹

Iguchi Tomoki 井口 巴樹

Research Projects

Research Products

Co-Researchers

Search for new seeds of anti-cancer agents targeting PARP from natural products

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非内因性経路に着目した植物由来サポニンのアポトーシス誘導メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of induction of apoptosis by steroidal glycosides via a mitochondria-independent pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Structure elucidation of 16 undescribed steroidal glycosides from the underground parts of Agapanthus africanus and apoptosis-inducing activity in small-cell lung cancer cell2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Oleanane-Type Triterpene Glycosides from the Saponaria officinalis L. Seeds and Apoptosis-Inducing Activity via Mitochondria2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phenolic compounds from the underground parts of Eremurus robustus and their cytotoxicity2022

Author(s)

Journal Title

Data Source

[Journal Article] Three novel furospirostanol glycosides and a steroidal alkaloid glycoside from the bulbs of Fritillaria camtschatcensis (L.) Ker Gawl., and their cytotoxicity2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Total of Eight Novel Steroidal Glycosides Based on Spirostan, Furostan, Pseudofurostan, and Cholestane from the Leaves of Cestrum newellii2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] ユリ科 Agapanthus africanus 地 下 部 か ら 単 離 さ れ た 新 規 ステロイド配糖体 の構造と SBC-3 ヒ ト 小 細 胞 肺 が ん 細 胞 に対する ア ポ ト ー シ ス 誘 導 活 性2022

Author(s)

Organizer

Data Source

IGUCHI TOMOKI 井口巴樹

Iguchi Tomoki 井口巴樹

[Presentation] ユリ科 Agapanthus africanus 地下部から単離された新規ステロイド配糖体の構造と SBC-3 ヒト小細胞肺がん細胞に対するアポトーシス誘導活性2022