Maki Koichiro 牧功一郎

Researcher Number	90849233
Other IDs
Affiliation (Current)	2025: 京都大学, 医生物学研究所, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都大学, 医生物学研究所, 助教 2020: 京都大学, ウイルス・再生医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator クロマチン / バイオメカニクス / 超解像度顕微鏡 / ゲノムDNA / 分子構造変化 / 転写 / トルク / 細胞老化 / DNA損傷-修復 / １本鎖DNA … More / 遺伝子転写 / 生体医工学 / 原子間力顕微鏡 / 力学計測 / 一本鎖ＤＮＡ / 力学的構造変化 / ＤＮＡ Less

Research Projects
(2 results)
Research Products
(14 results)

骨細胞のクロマチン動態を介した力感知メカニズムの解明Principal Investigator
- Principal Investigator
  
  牧功一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto University
Elucidating mechano-sensing mechanisms by transcriptional machineriesPrincipal Investigator
- Principal Investigator
  
  Maki Koichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] The nucleolar shell provides anchoring sites for DNA untwisting2024
- Author(s)
  Fukute Jumpei、Maki Koichiro、Adachi Taiji
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1 Pages: 83-83
- DOI
  10.1038/s42003-023-05750-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17196, KAKENHI-PROJECT-23KJ1255
[Journal Article] Vasculature atrophy causes a stiffened microenvironment that augments epidermal stem cell differentiation in aged skin2022
- Author(s)
  Ryo Ichijo、Koichiro Maki、Mio Kabata、Teruasa Murata、Arata Nagasaka、Seiichiro Ishihara、Hisashi Haga、Tetsuya Honda、Taiji Adachi、Takuya Yamamoto、Fumiko Toyoshima
- Journal Title
  
  Nature Aging
  
  Volume: 2 Issue: 7 Pages: 592-600
- DOI
  10.1038/s43587-022-00244-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21K16209, KAKENHI-PROJECT-20K20180
[Journal Article] Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling2020
- Author(s)
  Maki Koichiro、Nava Michele M.、Villeneuve Clementine、Chang Minki、Furukawa Katsuko S.、Ushida Takashi、Wickstrom Sara A.
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Issue: 2 Pages: 247643-247643
- DOI
  10.1242/jcs.247643
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20180, KAKENHI-PROJECT-19H01173
[Presentation] Mechanical behaviors of nuclear chromatin in chondrocytes under hydrostatic pressure2023
- Author(s)
  牧功一郎
- Organizer
  日本生物物理学会　第61回年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17196
[Presentation] 核内クロマチンを介した力感知機構の理解に向けて2023
- Author(s)
  牧功一郎
- Organizer
  第75回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17196
[Presentation] AFM を用いた生体組織・単一分子の力学計測2023
- Author(s)
  牧功一郎
- Organizer
  日本顕微鏡学会 SPM研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K17196
[Presentation] Hydrostatic pressure induces heterochromatin remodeling in chondrocytes2023
- Author(s)
  Koichiro Maki, Katsuko Furukawa, Takashi Ushida
- Organizer
  6th Japan-Switzerland Workshop on Biomechanics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17196
[Presentation] In situ imaging of single-stranded DNA in a cell nucleus2023
- Author(s)
  Koichiro Maki, Jumpei Fukute, Taiji Adachi
- Organizer
  6th Japan-Switzerland Workshop on Biomechanics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K17196
[Presentation] 細胞核内における一本鎖 DNA 凝集体のイメージング2022
- Author(s)
  牧功一郎
- Organizer
  第34回バイオエンジニアリング講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K20180
[Presentation] Single-stranded DNA forms condensates surrounding nucleoli2022
- Author(s)
  牧功一郎, 福手淳平, 安達泰治
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K20180
[Presentation] Fluorescence imaging of underwound DNA in the cell nucleus2022
- Author(s)
  福手淳平，牧功一郎，安達泰治
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20K20180
[Presentation] A novel fluorescent technique for single-stranded DNA in cell nucleus: toward understanding biomechanical behaviors of genomic DNA2022
- Author(s)
  Koichiro Maki, Jumpei Fukute, Takashi Suetake, Taiji Adachi
- Organizer
  9th World Congress of Biomechanics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20180
[Presentation] ATP枯渇条件における細胞核内DNAライブイメージング2021
- Author(s)
  福手淳平、牧功一郎、安達泰治
- Organizer
  日本バイオレオロジー学会
- Data Source
  KAKENHI-PROJECT-20K20180
[Presentation] DNA 超らせん形成が核内クロマチンのアクセシビリティに与える効果2021
- Author(s)
  福手淳平、牧功一郎、安達泰治
- Organizer
  日本機械学会第 31 回バイオフロンティア講演会
- Data Source
  KAKENHI-PROJECT-20K20180

Maki Koichiro 牧 功一郎

Research Projects

Research Products

骨細胞のクロマチン動態を介した力感知メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating mechano-sensing mechanisms by transcriptional machineriesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The nucleolar shell provides anchoring sites for DNA untwisting2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vasculature atrophy causes a stiffened microenvironment that augments epidermal stem cell differentiation in aged skin2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mechanical behaviors of nuclear chromatin in chondrocytes under hydrostatic pressure2023

Author(s)

Organizer

Data Source

[Presentation] 核内クロマチンを介した力感知機構の理解に向けて2023

Author(s)

Organizer

Data Source

[Presentation] AFM を用いた生体組織・単一分子の力学計測2023

Author(s)

Organizer

Data Source

[Presentation] Hydrostatic pressure induces heterochromatin remodeling in chondrocytes2023

Author(s)

Organizer

Data Source

[Presentation] In situ imaging of single-stranded DNA in a cell nucleus2023

Author(s)

Organizer

Data Source

[Presentation] 細胞核内における一本鎖 DNA 凝集体のイメージング2022

Author(s)

Organizer

Data Source

[Presentation] Single-stranded DNA forms condensates surrounding nucleoli2022

Author(s)

Organizer

Data Source

[Presentation] Fluorescence imaging of underwound DNA in the cell nucleus2022

Author(s)

Organizer

Data Source

[Presentation] A novel fluorescent technique for single-stranded DNA in cell nucleus: toward understanding biomechanical behaviors of genomic DNA2022

Author(s)

Organizer

Data Source

[Presentation] ATP枯渇条件における細胞核内DNAライブイメージング2021

Author(s)

Organizer

Data Source

[Presentation] DNA 超らせん形成が核内クロマチンのアクセシビリティに与える効果2021

Author(s)

Organizer

Data Source

Maki Koichiro 牧功一郎