Hatano Makoto 波多野誠

Researcher Number	90860669
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 学術研究員(寄附金)
Affiliation (based on the past Project Information) *help	2022 – 2023: 山口大学, 医学部附属病院, 学術研究員(寄附金) 2020 – 2021: 山口大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 網膜変性 / 神経保護 / VEGF / HSF / HSP / HSF1

熱ショックタンパク質と血管内皮増殖因子による網膜神経保護の病態解明Principal Investigator
- Principal Investigator
  
  波多野誠
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamaguchi University
Pathophysiology of heat shock transcription factor 1 in retinal degenerative diseases and development of retinal neuroprotective drugsPrincipal Investigator
- Principal Investigator
  
  Hatano Makoto
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamaguchi University

All 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Use of Ranibizumab for evaluating focal laser combination therapy for refractory diabetic macular edema patients: an exploratory study on the RELAND trials2023
- Author(s)
  Hatano Makoto、Wakuta Makiko、Yamamoto Kazutaka、Arai Eika、Enoki Miho、Fujimoto Kazushi、Yamauchi Kazuhiko、Ishikawa Keijiro、Sonoda Koh-Hei、Kimura Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 22965-22965
- DOI
  10.1038/s41598-023-48665-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16971
[Journal Article] Evaluation of microaneurysms as predictors of therapeutic response to anti-VEGF therapy in patients with DME2022
- Author(s)
  Hatano M，Higashijima F，Yoshimoto T，Ogata T，Ohta M，Kobayashi Y，Wakuta M，Yanai R，Kimura K
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 11 Pages: e0277920-e0277920
- DOI
  10.1371/journal.pone.0277920
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09743, KAKENHI-PROJECT-22K16971, KAKENHI-PROJECT-20K09805
[Journal Article] Inhibition of epithelial-mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist2021
- Author(s)
  Kobayashi Y，Tokuda K，Yamashiro C，Higashijima F，Yoshimoto T，Ohta M，Ogata T，Ashimori A，Hatano M，Kobayashi M，Uchi SH，Wakuta M，Kimura K
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 11842-11842
- DOI
  10.1038/s41598-021-90618-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18344, KAKENHI-PROJECT-20K18383, KAKENHI-PROJECT-20K18384, KAKENHI-PROJECT-20K09790, KAKENHI-PROJECT-20K09805
[Journal Article] Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon’s capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-102021
- Author(s)
  Yamashiro C，Tokuda K，Kobayashi Y，Higashijima F，Yoshimoto T，Ohta M，Ogata T，Ashimori A，Kobayashi M，Hatano M，Uchi SH，Wakuta M，Kimura K
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 16096-16096
- DOI
  10.1038/s41598-021-94852-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18344, KAKENHI-PROJECT-20K18383, KAKENHI-PROJECT-20K18384, KAKENHI-PROJECT-20K09790, KAKENHI-PROJECT-20K09805
[Journal Article] A Trinity regimen with aflibercept for treatment-naive neovascular age-related macular degeneration: 2-year outcomes2020
- Author(s)
  Wakuta M，Nomi N，Ogata T，Ohta M，Yamashiro C，Hatano M，Yanai R，Tokuda K，Kimura K
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol
  
  Volume: 258 Issue: 8 Pages: 1663-1670
- DOI
  10.1007/s00417-020-04745-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09790, KAKENHI-PROJECT-20K18344, KAKENHI-PROJECT-18K09449
[Journal Article] Role of the Neurokinin-1 Receptor in the Promotion of Corneal Epithelial Wound Healing by the Peptides FGLM-NH2 and SSSR in Neurotrophic Keratopathy2020
- Author(s)
  Yanai R，Nishida T，Hatano M，Uchi SH，Yamada N, Kimura K
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 61 Issue: 8 Pages: 29-29
- DOI
  10.1167/iovs.61.8.29
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18344, KAKENHI-PROJECT-18K09449
[Presentation] 光誘因性の網膜変性モデルにおけるHSF1を介した神経保護への関連遺伝子の検討2022
- Author(s)
  東島　史明，佐久間　彩乃，長谷川　実茄，濱田　和花，吉本　拓矢，緒方　惟彦，芦森　温茂，波多野　誠，木村　和博
- Organizer
  第126回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22K16971
[Presentation] 免疫チェックポイント阻害剤2剤により重篤なVogt-小柳-原田病様症候群を発症した一例2022
- Author(s)
  湧田　真紀子，竹中　優嘉，太田　真実，緒方　惟彦，小林　由佳，波多野　誠，山内　一彦，木村　和博
- Organizer
  第126回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-22K16971
[Presentation] Severe Vogt-Koyanagi-Harada disease-like uveitis by combination therapy of two immune check point inhibitors for malignant melanoma2022
- Author(s)
  Hamada W，Wakuta M，Ohta M，Ogata T，Kobayashi Y，Hatano M，Yamauchi K，Kimura K
- Organizer
  The 15th Joint Meeting of Chinese-Japanese-Korean Ophthalmologists
- Data Source
  KAKENHI-PROJECT-22K16971
[Presentation] Evaluation of microaneurysms in anti-VEGF-resistant diabetic macula edema2022
- Author(s)
  Ogata T，Hatano M，Ohta M，Kobayashi Y，Wakuta M，Yanai R，Kimura K
- Organizer
  FUJIRETINA
- Data Source
  KAKENHI-PROJECT-22K16971
[Presentation] パクリタキセルの関与が疑われた難治性糖尿病黄斑浮腫の1例2022
- Author(s)
  佐久間　彩乃，波多野　誠，東島　史明，太田　真実，緒方　惟彦，小林　由佳，湧田　真紀子，木村　和博
- Organizer
  第28回日本糖尿病眼学会
- Data Source
  KAKENHI-PROJECT-22K16971
[Presentation] 眼科スタッフのための糖尿病診療に必要なKeyword＆Trivia2021
- Author(s)
  波多野　誠
- Organizer
  第15回やまぐち眼科スタッフ講習会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 加齢黄斑変性に対するレスキューPDTの有効性に関与する因子の検討2021
- Author(s)
  太田　真実，湧田　真紀子，能美　なな実，緒方　惟彦，波多野　誠，柳井　亮二，木村　和博
- Organizer
  第137回山口県眼科医会春季総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] A new method of evaluation system of anterior chamber pressure for phacoemulsification2021
- Author(s)
  宮嵜　智景，長谷川　実茄，緒方　惟彦，波多野　誠，柳井　亮二，木村　和博
- Organizer
  第75回日本臨床眼科学会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 滲出型加齢黄斑変性の抗新生血管療法における導入期治療後の再発性に関与する因子2021
- Author(s)
  湧田　真紀子，能美　なな実，太田　真実，小林　由佳，竹中　優嘉，東島　史明，緒方　惟彦，波多野　誠，柳井　亮二，木村　和博
- Organizer
  第60回日本網膜硝子体学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 当院における 3Dビジュアルシステム使用の実際2021
- Author(s)
  波多野　誠，宮嵜　智景，長谷川　実茄，緒方　惟彦，柳井　亮二，木村　和博
- Organizer
  第71回山口眼科手術懇話会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] RAR-α agonistによるRPE細胞におけるEMT抑制作用2021
- Author(s)
  小林　由佳，山城　知恵美，東島　史明，吉本　拓矢，緒方　惟彦，芦森　温茂，小林　正明，波多野　誠，湧田　真紀子，柳井　亮二，徳田　和央，木村　和博
- Organizer
  第125回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 糖尿病黄斑浮腫患者へのラニビズマブ非反応群への局所レーザー併用療法の評価に関する探索的研究2021
- Author(s)
  波多野　誠，湧田　真紀子，山本　和隆，新井　栄華，榎　美穂，冨士本　一志，山内　一彦，石川　桂二郎，園田　康平，木村　和博
- Organizer
  第60回日本網膜硝子体学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] Evaluation of microaneurysms in α-VEGF-resistant DME2021
- Author(s)
  波多野　誠，太田　真実，小林　由佳，湧田　真紀子，柳井　亮二，木村　和博
- Organizer
  第27回日本糖尿病眼学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 免疫関連副作用による乳頭炎型Vogt-小柳-原田病様症候群と考えられた一例2021
- Author(s)
  竹中　優嘉，湧田　真紀子，太田　真実，緒方　惟彦，小林　由佳，波多野　誠，山内　一彦，木村　和博
- Organizer
  第138回山口県眼科医会秋季総会並びに集談会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] BACによるテノン嚢線維芽細胞の形態変化に対する抗炎症性サイトカインの抑制効果2021
- Author(s)
  山城　知恵美，徳田　和央，小林　由佳，小林　正明，波多野　誠，永井　智彦，寺西　慎一郎，徳田　信子，木村　和博
- Organizer
  第125回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] ぶどう膜炎続発緑内障に対するROCK阻害薬による早期の眼圧下降効果2021
- Author(s)
  柳井　亮二，内　翔平，緒方　惟彦，波多野　誠，小林　正明，永井智彦，寺西　慎一郎，木村　和博
- Organizer
  第54回日本眼炎症学会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 無硝子体眼の治療抵抗性糖尿病黄斑浮腫に対してt-PA硝子体注射が有用であった一例2020
- Author(s)
  青木　連，波多野　誠，緒方　惟彦，湧田　真紀子，柳井　亮二，木村　和博
- Organizer
  第74回日本臨床眼科学会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 光誘因性の網膜変性モデルにおけるHSF1の神経保護性についての検討2020
- Author(s)
  波多野　誠，徳田　和央，小林　由佳，山城　知恵美，内　翔平，小林　正明，柳井　亮二，木村　和博
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] RAR-α agonistによるsubretinal fibrosisの抑制作用2020
- Author(s)
  小林　由佳，山城　知恵美，小林　正明，波多野　誠，徳田　和央，柳井　亮二，木村　和博
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 点眼防腐剤によるテノン嚢線維芽細胞の形態変化に対する角膜上皮細胞の抑制作用と機序2020
- Author(s)
  山城　知恵美，徳田　和央，小林　由佳，小林　正明，波多野　誠，永井　智彦，寺西　慎一郎，徳田　信子，木村　和博
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-20K18344
[Presentation] 網膜色素上皮細胞におけるネクローシスによる血管内皮増殖因子の分泌に関する研究2020
- Author(s)
  波多野　誠
- Organizer
  第136回山口県眼科医会秋季総会並びに集談会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18344

1. YANAI Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 木村和博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 徳田信子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 徳田和央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 湧田真紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatano Makoto 波多野 誠

Research Projects

Research Products

Co-Researchers

熱ショックタンパク質と血管内皮増殖因子による網膜神経保護の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiology of heat shock transcription factor 1 in retinal degenerative diseases and development of retinal neuroprotective drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Use of Ranibizumab for evaluating focal laser combination therapy for refractory diabetic macular edema patients: an exploratory study on the RELAND trials2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of microaneurysms as predictors of therapeutic response to anti-VEGF therapy in patients with DME2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of epithelial-mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon’s capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-102021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Trinity regimen with aflibercept for treatment-naive neovascular age-related macular degeneration: 2-year outcomes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the Neurokinin-1 Receptor in the Promotion of Corneal Epithelial Wound Healing by the Peptides FGLM-NH2 and SSSR in Neurotrophic Keratopathy2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 光誘因性の網膜変性モデルにおけるHSF1を介した神経保護への関連遺伝子の検討2022

Author(s)

Organizer

Data Source

[Presentation] 免疫チェックポイント阻害剤2剤により重篤なVogt-小柳-原田病様症候群を発症した一例2022

Author(s)

Organizer

Data Source

[Presentation] Severe Vogt-Koyanagi-Harada disease-like uveitis by combination therapy of two immune check point inhibitors for malignant melanoma2022

Author(s)

Organizer

Data Source

[Presentation] Evaluation of microaneurysms in anti-VEGF-resistant diabetic macula edema2022

Author(s)

Organizer

Data Source

[Presentation] パクリタキセルの関与が疑われた難治性糖尿病黄斑浮腫の1例2022

Author(s)

Organizer

Data Source

[Presentation] 眼科スタッフのための糖尿病診療に必要なKeyword＆Trivia2021

Author(s)

Organizer

Data Source

[Presentation] 加齢黄斑変性に対するレスキューPDTの有効性に関与する因子の検討2021

Author(s)

Organizer

Data Source

[Presentation] A new method of evaluation system of anterior chamber pressure for phacoemulsification2021

Author(s)

Organizer

Data Source

[Presentation] 滲出型加齢黄斑変性の抗新生血管療法における導入期治療後の再発性に関与する因子2021

Author(s)

Hatano Makoto 波多野誠