Watanabe Kenji 渡辺憲史

Researcher Number	90866766
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任研究員 2025: 慶應義塾大学, 医学部(信濃町), 研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立長寿医療研究センター, 研究所老化ストレス応答研究プロジェクトチーム, 研究員 2020 – 2021: 国立研究開発法人国立長寿医療研究センター, 老化ストレス応答研究プロジェクトチーム, 研究員 2020: 国立研究開発法人国立長寿医療研究センター, 老化ストレス応答研究PT, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 統合的ストレス応答 / 加齢性骨組織変化 / ミトコンドリア / ロコモティブシンドローム / 核構造 / ミトコンドリア機能不全 / 骨代謝 / 核構造異常 / ミトコンドリアストレス応答 / ATF4 … More / 核膜構造 / 骨代謝制御 / 骨粗鬆症 / 加齢性組織変化 … More Except Principal Investigator 骨細胞 / ミトコンドリア / 組織連関 / 骨格筋 / 細胞老化 / ストレス応答 Less

骨細胞老化におけるATF4を介したラミンタンパク質の発現制御機構の解明Principal Investigator
- Principal Investigator
  
  渡辺憲史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Center for Geriatrics and Gerontology
骨細胞由来の骨格筋恒常性阻害因子の探索研究
- Principal Investigator
  
  清水孝彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
Analyze of nuclear deformation caused by mitochondria dysfunciton in osteocytesPrincipal Investigator
- Principal Investigator
  
  Watanabe Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Center for Geriatrics and Gerontology
Molecular mechanism of osteocyte senescence by mitochondrial retrograde signaling
- Principal Investigator
  
  Shimizu Takahiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  National Center for Geriatrics and Gerontology

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] ミトコンドリアダイナミクス2021
- Author(s)
  渡辺憲史, 澁谷修一, 清水孝彦
- Publisher
  エヌ・ティー・エス
- ISBN
  4860437462
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] GDE5 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice.2024
- Author(s)
  Aisyah, R., Ohshima, N., Watanabe, D., Nakagawa, Y., Sakuma, T., Nitschke, F., Nakamura, M., Sato, K., Nakahata, K., Yokoyama, C., Kumrungsee, K., Shimizu, T., Sotomaru, Y., Takeo, T., Nakagata, N., Izumi, T., Minassian, B.A., Miura, S., Yamamoto, T., Wada, M., and Yanaka, N.
- Journal Title
  
  Commun. Biol
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential.2024
- Author(s)
  Tamagawa, S., Sakai, D., Nojiri, H., Nakamura, Y., Warita, T., Matsushita, E., Schol, J., Soma, H., Ogasawara, S., Munesada, D., Koike, M., Shimizu, T., Sato, M., Ishijima, M., Watanabe, M.
- Journal Title
  
  Redox Biol
  
  Volume: 71 Pages: 103091-103091
- DOI
  10.1016/j.redox.2024.103091
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-20H03809
[Journal Article] 骨格筋特異的SOD2欠損はミトコンドリア機能不全に伴う運動不耐を引き起こす2023
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Journal Title
  
  基礎老化研究誌
  
  Volume: 47 Pages: 32-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] Insulin resistance induces earlier initiation of cognitive dysfunction mediated by cholinergic deregulation in a mouse model of Alzheimer’s disease.2023
- Author(s)
  Izuo, N., Watanabe, N., Noda, Y., Saito, T., Saido, T.C., Yokote, K., Hotta, H., Shimizu, T.
- Journal Title
  
  Aging Cell
  
  Volume: 22 Issue: 11 Pages: 1-13
- DOI
  10.1111/acel.13994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-23K07007, KAKENHI-PROJECT-23K20363
[Journal Article] Exploring for compounds that enhance motor function using muscle fatigue-model mice2023
- Author(s)
  澁谷修一，渡辺憲史，桜庭大樹，阿部卓哉，清水孝彦
- Journal Title
  
  Functional Food Research
  
  Volume: 19 Issue: 0 Pages: 45-49
- DOI
  10.32153/ffr.ffr19_p45-49
- ISSN
  2432-3357, 2434-3048
- Year and Date
  2023-10-12
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] 骨格筋特異的SOD2欠損はミトコンドリア機能不全に伴う運動不耐を引き起こす2023
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Journal Title
  
  基礎老化研究誌
  
  Volume: 47 Pages: 32-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] 酸化ストレスと骨格筋老化2022
- Author(s)
  清水孝彦, 渡辺憲史, 澁谷修一
- Journal Title
  
  実験医学
  
  Volume: 40 Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] Natural compounds that enhance the motor function in a mouse model of muscle fatigue.2022
- Author(s)
  Shuichi, S., Watanabe, K., Sakuraba, D., Abe, T., and Shimizu, T.
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 12 Pages: 3073-3073
- DOI
  10.3390/biomedicines10123073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-20H03583
[Journal Article] 加齢脳とストレス応答異常2022
- Author(s)
  清水孝彦, 渡辺憲史, 澁谷修一
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 33 Pages: 947-955
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] Acai pulp upregulates erythropoietin by inducing renal hypoxic condition in mice2022
- Author(s)
  澁谷修一，渡辺憲史，Mario Jose Villegas Yata，清水孝彦.
- Journal Title
  
  Functional Food Research
  
  Volume: 18 Issue: 0 Pages: 65-69
- DOI
  10.32153/ffr.ffr18_p65-69
- ISSN
  2432-3357, 2434-3048
- Year and Date
  2022-09-12
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-20H03583
[Journal Article] 酸化ストレスと運動器老化　特集：老化はなぜ進むのか?2022
- Author(s)
  清水孝彦, 澁谷修一, 渡辺憲史
- Journal Title
  
  BIO Clinica
  
  Volume: 37 Pages: 1287-1292
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] 酸化ストレスと骨格筋老化2022
- Author(s)
  清水孝彦, 渡辺憲史, 澁谷修一
- Journal Title
  
  実験医学
  
  Volume: 40 Pages: 78-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] 加齢脳とストレス応答異常2022
- Author(s)
  清水孝彦, 渡辺憲史, 澁谷修一
- Journal Title
  
  老年精神医学雑誌
  
  Volume: 33 Pages: 947-955
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] 酸化ストレスと運動器老化　特集：老化はなぜ進むのか?2022
- Author(s)
  清水孝彦, 澁谷修一, 渡辺憲史
- Journal Title
  
  BIO Clinica
  
  Volume: 37 Pages: 1287-1292
- Data Source
  KAKENHI-PROJECT-22K19607
[Journal Article] Xanthine oxidoreductase-mediated superoxide production is not involved in the age-related pathologies of Sod1-deficient mice2021
- Author(s)
  Shibuya, S., Watanabe, K., Ozawa, Y., Shimizu, T.
- Journal Title
  
  Int J. Mol. Sci.
  
  Volume: 22 Issue: 7 Pages: 3542-3542
- DOI
  10.3390/ijms22073542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] Pathological relationship between intracellular superoxide metabolism and p53 signaling in mice2020
- Author(s)
  Watanabe, K., Shibuya, S., Ozawa, Y., Toda, T., Shimizu, T.
- Journal Title
  
  Int J. Mol. Sci.
  
  Volume: 22 Issue: 7 Pages: 3548-3548
- DOI
  10.3390/ijms22073548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03583
[Journal Article] Cerebral artery dilation during transient ischemia is impaired by mechanical barrier of amyloid β deposition around cerebral artery in Alzheimer’s disease model mice2020
- Author(s)
  Watanabe, N., Noda, Y., Iimura, K., Shimizu, T., Hotta, H.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 70 Issue: 1 Pages: 57-57
- DOI
  10.1186/s12576-020-00785-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-23K20363
[Presentation] Superoxide Dismutase 2 Deficiency Accelerates Age-related Spontaneous Intervertebral Disc Degeneration In Mice2024
- Author(s)
  Shota Tamagawa, Daisuke Sakai, Hidetoshi Nojiri, Takayuki Warita, Jordy Schol, Takahiko Shimizu, Masato Sato, Muneaki Ishijima, Masahiko Watanabe
- Organizer
  Orthopaedic Research Society (ORS) 2024 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] SOD1欠損マウスを用いた健康食品の抗老化作用の評価2024
- Author(s)
  桜庭大樹、澁谷修一、渡辺憲史、阿部卓哉、大平はる香、山本貴司、永田岳史、山口芳正、清水孝彦
- Organizer
  第20回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Mitochondrial stress response in osteocytes regulates nuclear structure and bone metabolism via ATF4-lamins-sclerostin axis in aged bone2024
- Author(s)
  Takahiko Shimizu, Kenji Watanabe, Shuichi Shibuya
- Organizer
  SAGL First Anniversary International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 細胞外マトリックス制御による老化様皮膚病態の改善作用2024
- Author(s)
  澁谷修一、上條真弘、渡辺憲史、清水孝彦
- Organizer
  第20回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 澁谷修一、上條真弘、渡辺憲史、清水孝彦2024
- Author(s)
  澁谷修一、上條真弘、渡辺憲史、清水孝彦
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Influence of amyloid β deposition around the pial artery on cerebral artery response during transient ischemia in Alzheimer’s disease model mice2023
- Author(s)
  Nobuhiro Watanabe, Yoshihiro Noda, Taeko Nemoto, Kaori Iimura, Takahiko Shimizu, Harumi Hotta
- Organizer
  Neurovascular Unit Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 速筋ミトコンドリアROSは可逆的にグリコーゲン代謝及び運動機能を調節する2023
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Organizer
  第9回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Integrated stress response caused by mitochondrial dysfunction induce age-related bone loss through nuclear deformation in osteocytes2023
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] アサイー果実抽出物は腎低酸素化を介して造血因子erythropoietin を増加する2023
- Author(s)
  澁谷修一、上條真弘、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  日本農芸化学会2023年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 筋疲労モデルマウスの運動機能を改善する機能性食品素材2023
- Author(s)
  澁谷修一、渡辺憲史、桜庭大樹、阿部卓哉、清水孝彦
- Organizer
  第19回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 新規ウェルナー早老症モデルマウスの老化病態解析2023
- Author(s)
  澁谷修一、渡辺憲史、清水孝彦
- Organizer
  第31回日本医学会総会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] インスリン抵抗性はアルツハイマー病モデルマウスにおいてアセチルコリン神経系異常を伴って早期の認知機能障害を引き起こす2023
- Author(s)
  "泉尾直孝、渡辺信博、野田義博、斉藤貴志、西道隆臣、横手幸太郎、堀田晴美、清水孝彦 "
- Organizer
  第76回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Regulation of MMP2 restores aging-related skin atrophy induced by SOD1 deficiency2023
- Author(s)
  澁谷修一、上條真弘、渡辺憲史、清水孝彦
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 骨細胞老化と核ラミナ構造変化2023
- Author(s)
  清水孝彦、渡辺憲史、澁谷修一
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 運動器疾患のジェロサイエンス研究2023
- Author(s)
  清水孝彦、渡辺憲史、澁谷修一
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Influence of amyloid β deposition around the pial artery on cerebral artery response during transient ischemia in Alzheimer’s disease model mice2023
- Author(s)
  Nobuhiro Watanabe, Yoshihiro Noda, Taeko Nemoto, Kaori Iimura, Takahiko Shimizu, Harumi Hotta
- Organizer
  Neurovascular Unit Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Mitochondria stress response induced ATF4 activation associated with nuclear deformation resulted in age-related bone loss2023
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K15753
[Presentation] Acai berry, the Brazilian Amazon palm plant, transiently upregulates erythropoietin by inducing a renal hypoxic condition in mice2023
- Author(s)
  Takahiko Shimizu, Shuichi Shibuya, Kenji Watanabe, Mario Jose Villegas Yata
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Integrated stress response caused by mitochondrial dysfunction induce age-related bone loss through nuclear deformation in osteocytes2023
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15753
[Presentation] 骨細胞老化における統合的ストレス応答の寄与2023
- Author(s)
  清水孝彦、渡辺憲史
- Organizer
  第23回日本抗加齢医学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Wrn and Recql5 deletions promote adipose senescence and dyslipidemia2023
- Author(s)
  Shuichi Shibuya, Kenji Watanabe, Takahiko Shimizu
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Mitochondria stress response induced ATF4 activation associated with nuclear deformation resulted in age-related bone loss2023
- Author(s)
  渡辺憲史、澁谷修一、野尻英俊、清水孝彦
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] アサイー果実抽出物は腎低酸素化を介して造血因子erythropoietin を増加する2023
- Author(s)
  澁谷修一、上條真弘、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  日本農芸化学会2023年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 速筋ミトコンドリアROSは可逆的にグリコーゲン代謝及び運動機能を調節する2023
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Organizer
  第9回骨格筋生物学研究会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 筋疲労モデルマウスの運動機能を改善する機能性食品素材2023
- Author(s)
  澁谷修一、渡辺憲史、桜庭大樹、阿部卓哉、清水孝彦
- Organizer
  第19回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] アサイー果実パルプ水溶液は腎低酸素誘導を介して造血因子erythropoietinを増加する2022
- Author(s)
  澁谷修一、戸田年彦、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  第18回ファンクショナルフード学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Mitochondrial ROS in fast muscle reversibly regulates glycogen metabolism and physical activity in mice2022
- Author(s)
  Shuichi Shibuya, Ikko Sakamoto, Kenji Watanabe, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  第45回(2022年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] 速筋ミトコンドリアROSはグリコーゲン代謝および運動機能を可逆的に調節する2022
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Mitochondrial ROS in fast muscle reversibly regulates glycogen metabolism and physical activity in mice2022
- Author(s)
  Shuichi Shibuya, Ikko Sakamoto, Kenji Watanabe, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  第45回(2022年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Mitochondrial dysfunction in osteocytes caused age-related bone loss due to the nuclear lamina abnormalities2022
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Keiji Kobayashi, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  第45回(2022年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Mitochondrial dysfunction in osteocytes caused age-related bone loss due to the nuclear lamina abnormalities2022
- Author(s)
  渡辺憲史、澁谷修一、清水孝彦
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20K18081
[Presentation] Mitochondrial dysfunction in osteocytes caused age-related bone loss due to the nuclear lamina abnormalities2022
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Keiji Kobayashi, Hidetoshi Nojiri, Takahiko Shimizu
- Organizer
  第45回(2022年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] ミトコンドリア機能不全を起因とする核ラミナ構造破綻が骨量減少の原因となる2022
- Author(s)
  渡辺憲史、澁谷修一、清水孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K18081
[Presentation] SOD/カタラーゼ模倣薬は接触皮膚炎を緩和する2022
- Author(s)
  岩田拓磨、澁谷修一、渡辺憲史、清水孝彦
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] アサイー果実は腎蔵の低酸素化を介して造血ホルモンを増加する2022
- Author(s)
  澁谷修一、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  第22回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 速筋ミトコンドリアROSはグリコーゲン代謝および運動機能を可逆的に調節する2022
- Author(s)
  澁谷修一、坂本一晃、渡辺憲史、野尻英俊、清水孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] アサイー果実は腎蔵の低酸素化を介して造血ホルモンを増加する2022
- Author(s)
  澁谷修一、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  第22回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] ミトコンドリア機能不全を起因とする核ラミナ構造破綻が骨量減少の原因となる2022
- Author(s)
  渡辺憲史、澁谷修一、清水孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Mitochondrial dysfunction in osteocytes caused age-related bone loss due to the nuclear lamina abnormalities2022
- Author(s)
  Kenji WATANABE, Shuichi SHIBUYA, Keiji KOBAYASHI, Hidetoshi NOJIRI, Takahiko SHIMIZU
- Organizer
  第45回日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20K18081
[Presentation] ミトコンドリア機能不全を起因とする核ラミナ構造破綻が骨量減少の原因となる2022
- Author(s)
  渡辺憲史、澁谷修一、清水孝彦
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K19607
[Presentation] Superoxide dismutase 2 is involved in the senescence of dentin-pulp complex.2021
- Author(s)
  Tomohiro Itoyama, Kenji Watanabe, Masataka Kadowaki, Hiroshi Kaneko, Shinichiro Yoshida, Takahiko Shimizu, Hidefumi Maeda
- Organizer
  The 19th Joint Scientific Meeting between Japan Endodontic Association and Korean Association of Endodontic 2021 (JEA-KAE 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 酸化ストレスを起因とした加齢性組織変化とp53シグナルの関連性2021
- Author(s)
  渡辺憲史、澁谷修一、清水孝彦
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Influence of amyloid β deposition around the cerebral artery on cerebrovascular response during transient ischemia2021
- Author(s)
  Nobuhiro Watanabe, Yoshihiro Noda, Taeko Nemoto, Kaori Iimura, Takahiko Shimizu, Harumi Hotta
- Organizer
  第44回(2021年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] アサイー果実抽出物は腎低酸素化を介して造血因子erythropoietinを増加する2021
- Author(s)
  澁谷修一、戸田年彦、渡辺憲史、Mario Jose Villegas Yata、清水孝彦
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] Pathological cross-talk between intracellular superoxide metabolism and p53 signaling in murine models2021
- Author(s)
  Kenji Watanabe, Shuichi Shibuya, Takahiko Shimizu
- Organizer
  第44回(2021年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 体性感覚刺激による脳血流増加反応に対するアミロイドβの影響2020
- Author(s)
  渡辺信博、野田義博、飯村佳織、清水孝彦、堀田晴美
- Organizer
  第43回(2020年)日本基礎老化学会大会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 白金/パラジウム黒色溶液はSOD/カタラーゼ活性を持つナノ医療素材である2020
- Author(s)
  澁谷修一、渡辺憲史、清水孝彦
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] 一過性脳虚血時の軟膜動脈拡張反応に対する血管周囲のアミロイドβ蓄積の影響2020
- Author(s)
  渡辺信博、野田義博、根本妙子、飯村佳織、清水孝彦、堀田晴美
- Organizer
  第73回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-20H03583
[Presentation] ADモデルマウスにおける大脳皮質動脈周囲のアミロイドβ蓄積が一過性虚血中の動脈径変化に対する影響2020
- Author(s)
  渡辺信博、野田義博、根本妙子、飯村佳織、清水孝彦、堀田晴美
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20H03583

1. Shimizu Takahiko (40301791)

# of Collaborated Projects: 2 results

# of Collaborated Products: 60 results
2. 澁谷修一 (70866342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 45 results

Watanabe Kenji 渡辺 憲史

Research Projects

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Co-Researchers

骨細胞老化におけるATF4を介したラミンタンパク質の発現制御機構の解明Principal Investigator

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骨細胞由来の骨格筋恒常性阻害因子の探索研究

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Analyze of nuclear deformation caused by mitochondria dysfunciton in osteocytesPrincipal Investigator

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Molecular mechanism of osteocyte senescence by mitochondrial retrograde signaling

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[Book] ミトコンドリアダイナミクス2021

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[Journal Article] GDE5 activity determines phosphatidylcholine composition in skeletal muscle and regulates contractile force in mice.2024

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[Journal Article] SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential.2024

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[Journal Article] 骨格筋特異的SOD2欠損はミトコンドリア機能不全に伴う運動不耐を引き起こす2023

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[Journal Article] Insulin resistance induces earlier initiation of cognitive dysfunction mediated by cholinergic deregulation in a mouse model of Alzheimer’s disease.2023

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[Journal Article] Exploring for compounds that enhance motor function using muscle fatigue-model mice2023

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[Journal Article] 骨格筋特異的SOD2欠損はミトコンドリア機能不全に伴う運動不耐を引き起こす2023

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[Journal Article] 酸化ストレスと骨格筋老化2022

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[Journal Article] Natural compounds that enhance the motor function in a mouse model of muscle fatigue.2022

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[Journal Article] 加齢脳とストレス応答異常2022

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[Journal Article] Acai pulp upregulates erythropoietin by inducing renal hypoxic condition in mice2022

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Watanabe Kenji 渡辺憲史

[Journal Article] 酸化ストレスと運動器老化　特集：老化はなぜ進むのか?2022

[Journal Article] 酸化ストレスと運動器老化　特集：老化はなぜ進むのか?2022