Danoy Mathieu DANOY MATHIEU

Researcher Number	90882621
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京大学, 大学院工学系研究科(工学部), 助教
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related / 0403:Biomedical engineering and related fields Except Principal Investigator Basic Section 90110:Biomedical engineering-related / Basic Section 27040:Biofunction and bioprocess engineering-related
Keywords	Principal Investigator Liver / hiPSCs / Pathophysiology / Metastasis / PDAC / Cancer / Macrophages / Fibroblasts / Stroma / Pancreas … More / Tumor / Coculture / Immune / Inflammation / Hepatocytes / LSECs / Disease / HSCs … More Except Principal Investigator iPSCs / Liver / MicroPhysiologicalSystem / multi cellular cultures / disease model / pluripotent stem cells / liver on chip / liver / organ on chip / liver disease model / hepatic disorders / hiPSCS / fatty acids / fibrosis / stem cells / liver organ on chip / 肝細胞分化 / 幹細胞 / 透析 / 肝分化 / 未分化増幅 / 透析操作 / 高密度培養 / 大量培養 / ヒトiPS細胞 Less

Pathophysiological model to recapitulate the progression of pancreatic ductal adenocarcinoma metastasized to the liver.Principal Investigator
- Principal Investigator
  
  DANOY MATHIEU
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Limitations of ultra-high density and low cost in amplification and differentiation of human iPS cells
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  The University of Tokyo
Liver fibrosis investigation using iPSCs hepatic derived organ on chip
- Principal Investigator
  
  LECLERC Eric
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Establishment of a physiologically-relevant liver model for disease screeningPrincipal Investigator
- Principal Investigator
  
  Danoy Mathieu
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0403:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro2024
- Author(s)
  Scheidecker Benedikt、Poulain Stephane、Sugimoto Masahiro、Kido Taketomo、Kawanishi Takumi、Miyajima Atsushi、Kim Soo Hyeon、Arakawa Hiroshi、Kato Yukio、Nishikawa Masaki、Danoy Mathieu、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  Biofabrication
  
  Volume: 16 Issue: 2 Pages: 025037-025037
- DOI
  10.1088/1758-5090/ad30c5
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K25188
[Journal Article] Transcriptomic and proteomic studies suggest the establishment of advanced zonation‐like profiles in humaninduced pluripotent stem cell‐derived liver sinusoidal endothelial cells and carboxypeptidase M‐positive liver progenitor cells cocultured in a fluidic microenvironment2023
- Author(s)
  Danoy M, Poulain S, Scheidecker B, Kim SH, Kido T, Miyajima A, Sakai Y, Leclerc E
- Journal Title
  
  Hepatology research
  
  Volume: 1 Issue: 7 Pages: 1-14
- DOI
  10.1111/hepr.13893
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25188, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips2022
- Author(s)
  Mathieu Danoy、Stephane Poulain、Benedikt Scheidecker、Rachid Jellali、Yannick Tauran、Marjorie Leduc、Johanna Bruce、Francoise Gilard、Bertrand Gakiere、Hiroshi Arakawa、Yukio Kato、Soo Hyeon Kim、Taketomo Kido、Atsushi Miyajima、Yasuyuki Sakai、Eric Leclerc
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 181 Pages: 108408-108408
- DOI
  10.1016/j.bej.2022.108408
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491, KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-21H02710
[Journal Article] Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment2021
- Author(s)
  Danoy Mathieu、Tauran Yannick、Poulain Stephane、Jellali Rachid、Bruce Johanna、Leduc Marjorie、Le Gall Morgane、Koui Yuta、Arakawa Hiroshi、Gilard Francoise、Gakiere Bertrand、Kato Yukio、Plessy Charles、Kido Taketomo、Miyajima Atsushi、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  APL Bioengineering
  
  Volume: 5 Issue: 2 Pages: 026104-026104
- DOI
  10.1063/5.0041227
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491, KAKENHI-PROJECT-21H02710
[Journal Article] Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells2021
- Author(s)
  Danoy Mathieu、Jellali Rachid、Tauran Yannick、Bruce Johanna、Leduc Marjorie、Gilard Fran?oise、Gaki?re Bertrand、Scheidecker Benedikt、Kido Taketomo、Miyajima Atsushi、Soncin Fabrice、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  Differentiation
  
  Volume: 120 Pages: 28-35
- DOI
  10.1016/j.diff.2021.06.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491
[Presentation] A transcriptomic study on the influence of the stimulation by a microfluidic environment for the induction of zonation-like patterns in carboxypeptidase M-positive human pluripotent stem cells-derived liver progenitor cells2022
- Author(s)
  Danoy M, Poulain S, Scheidecker B, Kim S.H, Kido T, Miyajima A, Sakai Y, Leclerc E
- Organizer
  WCB, World congress of biomechanics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25188
[Presentation] Optimization of In vitro Culture Condition to Maintain Hepatic Stellate Cell in Quiescence2021
- Author(s)
  Ya Gong , Mathieu Danoy , Taketomo Kido , Masaki Nishikawa , Atsushi Miyajima , Yasuyuki Sakai
- Organizer
  細胞アッセイ研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K22491

1. 酒井康行 (00235128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 西川昌輝 (40843149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. LECLERC Eric (30759436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 木戸丈友

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Danoy Mathieu DANOY MATHIEU

Research Projects

Research Products

Co-Researchers

Pathophysiological model to recapitulate the progression of pancreatic ductal adenocarcinoma metastasized to the liver.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Limitations of ultra-high density and low cost in amplification and differentiation of human iPS cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Liver fibrosis investigation using iPSCs hepatic derived organ on chip

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a physiologically-relevant liver model for disease screeningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro2024

Author(s)

Journal Title

DOI

Data Source

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of the proteome and metabolome of human liver sinusoidal endothelial-like cells derived from induced pluripotent stem cells2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] A transcriptomic study on the influence of the stimulation by a microfluidic environment for the induction of zonation-like patterns in carboxypeptidase M-positive human pluripotent stem cells-derived liver progenitor cells2022

Author(s)

Organizer

Data Source

[Presentation] Optimization of In vitro Culture Condition to Maintain Hepatic Stellate Cell in Quiescence2021

Author(s)

Organizer

Data Source