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Yamatani Kotoko  山谷 琴子

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YAMATANI KOTOKO  山谷 琴子

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Researcher Number 90909805
Other IDs
Affiliation (Current) 2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2021 – 2023: 順天堂大学, 医学部, 非常勤助教
Review Section/Research Field
Principal Investigator
Basic Section 52010:General internal medicine-related / 0902:General internal medicine and related fields
Keywords
Principal Investigator
ベネトクラックス / デシダビン / 治療抵抗性 / デシタビン / ベネトクラクス / 急性骨髄性白血病 / 治療効果識別マーカー / 高齢者急性骨髄性白血病 / 治療効果予測マーカー / DNAメチル基転移酵素阻害剤 … More / 白血病 / methylation assay / 治療予測マーカー / DNAメチル化阻害剤 / BCL2阻害剤 / メチル化 / RNA-seq Less
  • Research Projects

    (2 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (2 People)
  •  高齢者白血病治療における適切な治療を選別しうる新規診断法の確立Principal Investigator

    • Principal Investigator
      山谷 琴子
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Juntendo University
  •  Exploration of Predictive Biomarkers for Combined BCL2 and Methylation Inhibitor Therapies in Elderly Leukemia PatientsPrincipal Investigator

    • Principal Investigator
      YAMATANI KOTOKO
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0902:General internal medicine and related fields
    • Research Institution
      Juntendo University

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML2022

    • Author(s)
      Yamatani K, Ai T, Saito K, Suzuki K, Hori A, Kinjo S, Ikeo K, Ruvolo V, Zhang W, Mak PY, Kaczkowski B, Harada H, Katayama K, Sugimoto Y, Myslinski J, Hato T, Miida T, Konopleva M, Hayashizaki Y, Carter BZ, Tabe Y, Andreeff M
    • Journal Title

      Translational Oncology

      Volume: 18 Pages: 101354-101354

    • DOI

      10.1016/j.tranon.2022.101354

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-21K06585, KAKENHI-PROJECT-21K07226, KAKENHI-PROJECT-21K20913, KAKENHI-PROJECT-19KK0221, KAKENHI-PROJECT-19H04355, KAKENHI-PROJECT-23K24235
  • [Presentation] PPARG and ASS1: Targets of metabolic alteration in Venetoclax / Decitabine resistant AML2023

    • Author(s)
      Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito1, Abhishek Maiti, Satoshi Yamashita, Abdullah Khasawneh, Faith Jessica Paran, Kala Hayes, Gautam Borthakur, Joe R Harman, Shinya Kimura, Courtney D. DiNardo, Thomas A Milne, Michael Andreeff, Yoko Tabe, Marina Konopleva
    • Organizer
      65th ASH Annual Meeting and Exposition
    • Data Source
      KAKENHI-PROJECT-21K20913
  • [Presentation] PPARG and ASS1: Targets of metabolic alteration in Venetoclax / Decitabine resistant AML2023

    • Author(s)
      Kotoko Yamatani, Tatsuro Watanabe, Kaori Saito1, Abhishek Maiti, Satoshi Yamashita, Abdullah Khasawneh, Faith Jessica Paran, Kala Hayes, Gautam Borthakur, Joe R Harman, Shinya Kimura, Courtney D. DiNardo, Thomas A Milne, Michael Andreeff, Yoko Tabe, Marina Konopleva
    • Organizer
      65th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14719
  • [Presentation] Diverse mechanisms of resistance to Decitabine and Venetoclax therapy in newly diagnosed and relapsed/refractory AML inferred by transcriptome analysis2022

    • Author(s)
      Kotoko Yamatani, Tatsuro Watanabe, Kaori Saitoh, KaZuhiro Nitta, Kanako Kinjo, Kazuho Ikeo, Takashi Miida, Shinya Kimura, Su Xiaoping, Marina Konopleva,Yoko Tabe
    • Organizer
      The 17th Congress of Asian Society of Clinical Pathology and Laboratory Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20913
  • [Presentation] Biomarkers of clinical resistance to Decitabine and Venetoclax therapy inferred by transcriptome and methylation analyses2022

    • Author(s)
      Kotoko Yamatani, Abhishek Maiti, Tatsuro Watanabe, Kaori Saitoh, Kala Hayes, Sonoko Kinjo, Kazuho Ikeo, Takashi Miida, Shinya Kimura, Courtney D. DiNardo, Su Xiaoping, Yoko Tabe, Marina Konopleva
    • Organizer
      64th ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20913
  • [Presentation] BCL2A1: A Novel Target in Refractory/Relapsed AML with FLT3-ITD/D835 Double Mutations2021

    • Author(s)
      2)Kotoko Yamatani, Bing Z. Carter, Marina Konopleva, Yoko Tabe, Michael Andreeff
    • Organizer
      SOHO 2021 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20913
  • [Presentation] Diverse mechanisms of resistance to Decitabine and Venetoclax therapy in newly diagnosed vs relapsed/refractory AML inferred by transcriptome analysis2021

    • Author(s)
      1)Kotoko Yamatani, Yoko Tabe, Abhishek Maiti, Tomohiko Ai, Kaori Saitoh, Kazuhiro Nitta, Kanako Kinjo, Kazuho Ikeo, Takashi Miida, Courtney D. DiNardo, Su Xiaoping, Marina Konopleva
    • Organizer
      63nd ASH Annual Meeting and Exposition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20913
  • 1.  HARADA Yuka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  原田 浩徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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