Horikoshi Susumu 堀越励

Researcher Number	90911587
Other IDs
Affiliation (Current)	2025: 広島大学, 病院(歯), 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 広島大学, 病院(歯), 助教 2021: 広島大学, 病院(歯), 歯科診療医
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / 0907:Oral science and related fields
Keywords	Principal Investigator 軟骨分化 / 骨再生 / 軟骨内骨化 / 間葉系幹細胞 / 軟骨細胞

軟骨誘導を施した間葉系幹細胞集塊による新規歯周組織再生療法の品質検査法の開発Principal Investigator
- Principal Investigator
  
  堀越励
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Development of a novel periodontal tissue regeneration therapy using mesenchymal stem cell clumps induced endochondral ossification ex vivo.Principal Investigator
- Principal Investigator
  
  Horikoshi Susumu
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Hiroshima University
Development of a novel periodontal tissue regeneration therapy using mesenchymal stem cell clumps generated with chondro-inductive mediumPrincipal Investigator
- Principal Investigator
  
  Horikoshi Susumu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0907:Oral science and related fields
- Research Institution
  Hiroshima University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] Distinctive Biological Properties between Mesenchymal Stem Cell Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems2023
- Author(s)
  Yoshino Mai、Kajiya Mikihito、Yoshii Hiroki、Morimoto Shin、Horikoshi Susumu、Tari Misako、Iwata Tomoyuki、Ouhara Kazuhisa、Ando Toshinori、Yoshimoto Tetsuya、Shintani Tomoaki、Mizuno Noriyoshi
- Journal Title
  
  Applied Sciences
  
  Volume: 13 Issue: 23 Pages: 12790-12790
- DOI
  10.3390/app132312790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-23K24533
[Journal Article] A Cartilaginous Construct with Bone Collar Exerts Bone-Regenerative Property Via Rapid Endochondral Ossification2023
- Author(s)
  Morimoto Shin、Kajiya Mikihito、Yoshii Hiroki、Yoshino Mai、Horikoshi Susumu、Motoike Souta、Iwata Tomoyuki、Ouhara Kazuhisa、Ando Toshinori、Yoshimoto Tetsuya、Shintani Tomoaki、Mizuno Noriyoshi
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 19 Issue: 6 Pages: 1812-1827
- DOI
  10.1007/s12015-023-10554-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-23K24533, KAKENHI-PROJECT-21K16993
[Journal Article] Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells2023
- Author(s)
  Yoshii Hiroki、Kajiya Mikihito、Yoshino Mai、Morimoto Shin、Horikoshi Susumu、Tari Misako、Motoike Souta、Iwata Tomoyuki、Ouhara Kazuhisa、Ando Toshinori、Yoshimoto Tetsuya、Shintani Tomoaki、Mizuno Noriyoshi
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 20 Issue: 1 Pages: 347-361
- DOI
  10.1007/s12015-023-10646-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060
[Journal Article] Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration2022
- Author(s)
  Ogawa Tomoya、Kajiya Mikihito、Horikoshi Susumu、Yoshii Hiroki、Yoshino Mai、Motoike Souta、Morimoto Shin、Sone Hisakatsu、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
- Journal Title
  
  Regenerative Therapy
  
  Volume: 20 Pages: 117-125
- DOI
  10.1016/j.reth.2022.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066
[Journal Article] Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model2022
- Author(s)
  Sone Hisakatsu、Kajiya Mikihito、Takeda Katsuhiro、Sasaki Shinya、Horikoshi Susumu、Motoike Souta、Morimoto Shin、Yoshii Hiroki、Yoshino Mai、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 16 Issue: 10 Pages: 945-955
- DOI
  10.1002/term.3343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09983, KAKENHI-PROJECT-22K17060, KAKENHI-PROJECT-20K09975, KAKENHI-PROJECT-21K21066, KAKENHI-PROJECT-23K24533
[Journal Article] Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification2021
- Author(s)
  Horikoshi Susumu、Kajiya Mikihito、Motoike Souta、Yoshino Mai、Morimoto Shin、Yoshii Hiroki、Ogawa Tomoya、Sone Hisakatsu、Iwata Tomoyuki、Ouhara Kazuhisa、Matsuda Shinji、Mizuno Noriyoshi、Kurihara Hidemi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 10 Pages: 1408-1408
- DOI
  10.3390/biomedicines9101408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10129, KAKENHI-PROJECT-21K21066
[Presentation] YAP/TAZメカノシグナルは間葉系幹細胞の細胞保護因子産生能を制御する2023
- Author(s)
  吉井寛毅, 加治屋幹人, 森本慎, 吉野舞, 堀越励, 田利美沙子, 谷口友梨, 松田真司, 佐々木慎也, 濱本結太, 岩田倫幸, 應原一久, 吉本哲也, 水野智仁
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K17060
[Presentation] 3次元培養間葉系幹細胞集塊を用いた骨髄脂肪組織様in vitroモデルの開発2023
- Author(s)
  吉野舞, 加治屋幹人, 森本慎, 吉井寛毅, 吉本哲也, 堀越励, 田利美沙子, 曽根久勝, 岩田倫幸, 應原一久, 松田真司, 佐々木慎也, 濱本結太, 谷口友梨, 水野智仁
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K17060
[Presentation] ボーンカラーを持った軟骨原基様構造物は早期に軟骨内骨化を介した骨再生を引き起こす2023
- Author(s)
  森本慎，加治屋幹人，堀越励，吉井寛毅，吉野舞，應原一久，松田真司，岩田倫幸，佐々木慎也，濱本結太，田利美沙子，谷口友梨，吉本哲也，水野智仁
- Organizer
  第66回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-22K17060
[Presentation] 間葉系幹細胞集塊Clumps of MSCs/ECM complexesによる歯周組織再生のメカニズム解析2021
- Author(s)
  曽根久勝、加治屋幹人、佐々木慎也、堀越励、小川智也、吉井寛毅、森本慎、吉野舞、松田真司、岩田倫幸、應原一久、水野智仁
- Organizer
  第60回広島県歯科医学会
- Data Source
  KAKENHI-PROJECT-21K21066
[Presentation] INF-γ前処理された間葉系幹細胞集塊Clumps of MSCs/ECM complexesは凍結保存後も免疫制御能・骨再生能を維持する2021
- Author(s)
  小川智也、加治屋幹人、堀越励、曽根久勝、吉井寛毅、森本慎、吉野舞、佐々木慎也、松田真司、岩田倫幸、應原一久、水野智仁
- Organizer
  第60回広島県歯科医学会
- Data Source
  KAKENHI-PROJECT-21K21066

1. MIKIHITO Kajiya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 應原一久

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Horikoshi Susumu 堀越 励

Research Projects

Research Products

Co-Researchers

軟骨誘導を施した間葉系幹細胞集塊による新規歯周組織再生療法の品質検査法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel periodontal tissue regeneration therapy using mesenchymal stem cell clumps induced endochondral ossification ex vivo.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel periodontal tissue regeneration therapy using mesenchymal stem cell clumps generated with chondro-inductive mediumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Distinctive Biological Properties between Mesenchymal Stem Cell Spheroids and Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes in 3D Culture Systems2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Cartilaginous Construct with Bone Collar Exerts Bone-Regenerative Property Via Rapid Endochondral Ossification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanosignaling YAP/TAZ-TEAD Axis Regulates the Immunomodulatory Properties of Mesenchymal Stem Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Xenotransplantation of cryopreserved human clumps of mesenchymal stem cells/extracellular matrix complexes pretreated with IFN-γ induces rat calvarial bone regeneration2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clumps of Mesenchymal Stem Cells/Extracellular Matrix Complexes Generated with Xeno-Free Chondro-Inductive Medium Induce Bone Regeneration via Endochondral Ossification2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] YAP/TAZメカノシグナルは間葉系幹細胞の細胞保護因子産生能を制御する2023

Author(s)

Organizer

Data Source

[Presentation] 3次元培養間葉系幹細胞集塊を用いた骨髄脂肪組織様in vitroモデルの開発2023

Author(s)

Organizer

Data Source

[Presentation] ボーンカラーを持った軟骨原基様構造物は早期に軟骨内骨化を介した骨再生を引き起こす2023

Author(s)

Organizer

Data Source

[Presentation] 間葉系幹細胞集塊Clumps of MSCs/ECM complexesによる歯周組織再生のメカニズム解析2021

Author(s)

Organizer

Data Source

[Presentation] INF-γ前処理された間葉系幹細胞集塊Clumps of MSCs/ECM complexesは凍結保存後も免疫制御能・骨再生能を維持する2021

Author(s)

Organizer

Data Source

Horikoshi Susumu 堀越励