HAMABE Toshihide 浜辺俊秀

… Alternative Names

浜辺俊秀ハマベトシヒデ

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Researcher Number	90963314
Affiliation (Current)	2025: 浜松医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2023: 静岡県立大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related Except Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator p300 / ヒストン修飾 / 膠芽腫 Except Principal Investigator 治療薬 / 多量体形成 / 心肥大 / 心筋細胞肥大 / ノックインマウス / 心不全 / ホモ多量体化 … More / GATA4 / p300 binding proteins / heart failure / fibrosis / cardiac hypertrophy / アセチル化 / 心筋肥大 / p300 Less

膠芽腫におけるp300-ヒストンアセチル化酵素活性による細胞増殖制御機構の解明Principal Investigator
- Principal Investigator
  
  浜辺俊秀
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  University of Shizuoka
The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failure
- Principal Investigator
  
  砂川陽一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Shizuoka
ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究
- Principal Investigator
  
  森本達也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Shizuoka

All 2024 2023

All Journal Article Presentation

[Journal Article] Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice2024
- Author(s)
  Sunagawa Yoichi、Tsukabe Ryosuke、Irokawa Yudai、Funamoto Masafumi、Suzuki Yuto、Yamada Miho、Shimizu Satoshi、Katanasaka Yasufumi、Hamabe-Horiike Toshihide、Kawase Yuto、Naruta Ryuya、Shimizu Kana、Mori Kiyoshi、Hosomi Ryota、Komiyama Maki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2344-2344
- DOI
  10.3390/ijms25042344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098, KAKENHI-PROJECT-21K08069
[Journal Article] Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice2024
- Author(s)
  Katanasaka Yasufumi、Yabe Harumi、Murata Noriyuki、Sobukawa Minori、Sugiyama Yuga、Sato Hikaru、Honda Hiroki、Sunagawa Yoichi、Funamoto Masafumi、Shimizu Satoshi、Shimizu Kana、Hamabe-Horiike Toshihide、Hawke Philip、Komiyama Maki、Mori Kiyoshi、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2344-2344
- DOI
  10.1038/s41467-024-46711-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098
[Journal Article] 6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure2023
- Author(s)
  Kawase Yuto、Sunagawa Yoichi、Shimizu Kana、Funamoto Masafumi、Hamabe-Horiike Toshihide、Katanasaka Yasufumi、Shimizu Satoshi、Hawke Philip、Mori Kiyoshi、Komiyama Maki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 9 Pages: 2232-2232
- DOI
  10.3390/nu15092232
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098, KAKENHI-PROJECT-21K08069
[Presentation] A Novel p300 Binding Protein 1 is Required for Pressure-overload Induced Cardiac Hypertrophy and Dysfunction in Mice2024
- Author(s)
  Sunagawa Y, Ishima A, Suzuki Y, Hamabe-Horiike H, Katanasaka Y, Hasegawa K, Morimoto T
- Organizer
  第88回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06098
[Presentation] 転写因子GATA4の多量体形成阻害はフェニレフリン誘導性の心筋細胞肥大を抑制した2023
- Author(s)
  須藤優、塚部凌輔、川瀬裕斗、清水聡史、浜辺俊秀、砂川陽一、船本雅文、清水果奈、刀坂泰史、長谷川浩二、森本達也
- Organizer
  第27回日本統合医療学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023
- Author(s)
  Ryosuke Tsukabe, Satoshi Shimizu, Yoishi Sunagawa, Yasufumi Katanasaka, Toshihide Hamabe, Masafumi Funamoto, Kana Shimizu, Maki Komiyama, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第27回日本心不全学会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] Curcumin誘導体Compound BはCurcuminと比べ低濃度で膠芽腫に対して抗腫瘍作用を示した2023
- Author(s)
  稲井恭子、浜辺俊秀、小野雅也、岩清水苑夏、伊藤亮、砂川陽一、刀坂泰史、荒川芳輝、長谷川浩二、森本達也
- Organizer
  第41回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14445
[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023
- Author(s)
  Ryosuke Tsukabe, Satoshi Shimizu, Yoichi Sunagawa, Yasufumi Katanasaka, Toshihide Hamabe-Horiike, Masafumi Funamoto, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 34th Great Wall International Congress of Cardiology (GW-ICC) & Asian Heart Society Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] 転写因子GATA4の多量体形成阻害は心筋細胞肥大を抑制した2023
- Author(s)
  須藤優、塚部凌輔、川瀬裕斗、清水聡史、浜辺俊秀、砂川陽一、船本雅文、清水果奈、刀坂泰史、長谷川浩二、森本達也
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] クルクミン類縁体化合物は膠芽腫に対してクルクミンよりも低濃度で抗腫瘍作用を示した2023
- Author(s)
  伊藤亮、浜辺俊秀、小野雅也、岩清水苑夏、稲井恭子、砂川陽一、刀坂泰史、荒川芳輝、長谷川浩二、森本達也
- Organizer
  第41回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14445

1. 砂川陽一 (30466297)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 森本達也 (50390779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 船本雅文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

HAMABE Toshihide 浜辺 俊秀

浜辺 俊秀 ハマベ トシヒデ

Research Projects

Research Products

Co-Researchers

膠芽腫におけるp300-ヒストンアセチル化酵素活性による細胞増殖制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] A Novel p300 Binding Protein 1 is Required for Pressure-overload Induced Cardiac Hypertrophy and Dysfunction in Mice2024

Author(s)

Organizer

Data Source

[Presentation] 転写因子GATA4の多量体形成阻害はフェニレフリン誘導性の心筋細胞肥大を抑制した2023

Author(s)

Organizer

Data Source

[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023

Author(s)

Organizer

Data Source

[Presentation] Curcumin誘導体Compound BはCurcuminと比べ低濃度で膠芽腫に対して抗腫瘍作用を示した2023

Author(s)

Organizer

Data Source

[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023

Author(s)

Organizer

Data Source

[Presentation] 転写因子GATA4の多量体形成阻害は心筋細胞肥大を抑制した2023

Author(s)

Organizer

Data Source

[Presentation] クルクミン類縁体化合物は膠芽腫に対してクルクミンよりも低濃度で抗腫瘍作用を示した2023

Author(s)

Organizer

Data Source

HAMABE Toshihide 浜辺俊秀

浜辺俊秀ハマベトシヒデ