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Hanai Hiroto  花井 洋人

ORCIDConnect your ORCID iD *help
Researcher Number 90964437
Other IDs
Affiliation (based on the past Project Information) *help 2022 – 2023: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / 0905:Surgery of the organs maintaining homeostasis and related fields
Keywords
Principal Investigator
肩腱板断裂 / 間葉系間質細胞 / エクソソーム / 細胞外小胞 / 間葉系幹細胞
  • Research Projects

    (2 results)
  • Research Products

    (7 results)
  •  IFNγ刺激したMSC由来細胞外小胞の肩腱板断裂に対する骨腱部修復促進効果の解明Principal Investigator

    • Principal Investigator
      花井 洋人
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  Effects of cytokine-stimulated MSC-derived extracellular vesicles on bone-tendon healing of shoulder rotator cuff tears.Principal Investigator

    • Principal Investigator
      Hanai Hiroto
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0905:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Osaka University

All 2023 2022

All Journal Article Presentation

  • [Journal Article] Small extracellular vesicles derived from human adipose‐derived mesenchymal stromal cells cultured in a new chemically‐defined contaminate‐free media exhibit enhanced biological and therapeutic effects on human chondrocytes in vitro and in a mouse osteoarthritis model2023

    • Author(s)
      Hanai Hiroto、Hart David A.、Jacob George、Shimomura Kazunori、Ando Wataru、Yoshioka Yusuke、Ochiya Takahiro、Nakagawa Shinicihi、Nakamura Masato、Okada Seiji、Nakamura Norimasa
    • Journal Title

      Journal of Extracellular Vesicles

      Volume: 12 Issue: 7

    • DOI

      10.1002/jev2.12337

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K15688, KAKENHI-PROJECT-23K08676, KAKENHI-PROJECT-22K20937, KAKENHI-PROJECT-23K24460
  • [Journal Article] Clinical Safety and Effectiveness of Adipose-Derived Stromal Cell vs Stromal Vascular Fraction Injection for Treatment of Knee Osteoarthritis: 2-Year Results of Parallel Single-Arm Trials2022

    • Author(s)
      Yokota Naomasa、Lyman Stephen、Hanai Hiroto、Shimomura Kazunori、Ando Wataru、Nakamura Norimasa
    • Journal Title

      The American Journal of Sports Medicine

      Volume: 50 Issue: 10 Pages: 2659-2668

    • DOI

      10.1177/03635465221107364

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20937, KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-23K24460
  • [Presentation] Extracellular vesicles with high purity derived from ASC cultured in a new medium suppresses progression of osteoarthritis in a mouse model2023

    • Author(s)
      花井洋人
    • Organizer
      17th ICRS World Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20937
  • [Presentation] 間葉系幹細胞由来細胞外小胞(エクソソーム)を用いた変形性膝関節症治への臨床応用2023

    • Author(s)
      花井洋人
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-22K20937
  • [Presentation] Extracellular vesicles with high purity derived from ASC cultured in a new medium suppresses progression of osteoarthritis in a mouse model2023

    • Author(s)
      花井洋人
    • Organizer
      17th ICRS World Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K15688
  • [Presentation] 変形性関節症に対する治療効果を有する高純度脂肪由来間葉系間質細胞由来 細胞外小胞の回収法の確立2023

    • Author(s)
      花井洋人
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-23K15688
  • [Presentation] 変形性関節症に対する治療効果を有する高純度脂肪由来間葉系間質細胞由来 細胞外小胞の回収法の確立2023

    • Author(s)
      花井洋人
    • Organizer
      第38回日本整形外科学会基礎学術集会
    • Data Source
      KAKENHI-PROJECT-22K20937

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