Relation between paracrine factors promoting adult neurogenesis and neurological diseases
Project/Area Number |
22700385
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Nerve anatomy/Neuropathology
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Research Institution | National Institute of Advanced Industrial Science and Technology |
Principal Investigator |
KUWABARA Tomoko 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 研究員 (90358391)
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Project Period (FY) |
2010 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
Keywords | 幹細胞 / 神経新生 / 神経 / うつ病 / 神経幹細胞 / 海馬 / 神経疾患 / ストレス |
Research Abstract |
We discovered a factor that causes the impairment of neurogenesis in the aged brain and in the brain under the neurological diseases. A mechanism has been identified by which stimuli including exercise re-activate the ability to generate newborn neurons.
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Report
(3 results)
Research Products
(21 results)
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[Journal Article] Insulin biosynthesis in neuronal progenitors derived from adult hippocampus and the olfactory bulb2011
Author(s)
Kuwabara T., Kagalwala M.N., Onuma Y., Ito Y., Warashina M., Terashima K., Sanosaka T., Nakashima K., Gage F.H., Asashima, M
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Journal Title
EMBO Mol.Med.
Volume: 3
Issue: 12
Pages: 742-754
DOI
Related Report
Peer Reviewed
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