Invention of prophylactic medicine for premature birth made from soybean.
Project/Area Number |
22591832
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Obstetrics and gynecology
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Research Institution | Nara Medical University |
Principal Investigator |
SADO Toshiyuki 奈良県立医科大学, 医学部, 講師 (50275335)
|
Co-Investigator(Kenkyū-buntansha) |
KOBAYASHI Hiroshi 奈良県立医科大学, 医学部, 教授 (40178330)
YOSHIDA Shozo 奈良県立医科大学, 医学部, 助教 (40347555)
NARUSE Sado 奈良県立医科大学, 医学部, 助教 (70453165)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 産科学 / 早産 / 炎症 / サイトカイン / 大豆 |
Research Abstract |
Premature birth caused poor prognosis in newborn. The aim of this study were to reveal anti-inflammation effect by soybean Kunitz trypsin inhibitor. Soybean Kunitz trypsin inhibitor suppressed the production of inflammatory cytokine. Therefore, soybean Kunitz trypsin inhibitor have anti-inflammation effect.
|
Report
(4 results)
Research Products
(126 results)
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[Journal Article] New insights into pattern recognition receptors and their ligands in gynecologic pathologies.2011
Author(s)
Yamada Y, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Yoshida S, Furukawa N, Nagai A, Tanase Y, Tsunemi T, Oi H, Kobayashi H.
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Journal Title
Hum Immunol.
Volume: 72
Pages: 213-218
Related Report
Peer Reviewed
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[Journal Article] Risk of carcinoma in women with ovarian endometrioma.2011
Author(s)
Kobayashi H, Kajihara H, Yamada Y, Tanase Y, Kanayama S, Furukawa N, Noguchi T, Haruta S, Yoshida S, Naruse K, Sado T, Oi H.
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Journal Title
Front Biosci
Volume: 3
Pages: 529-539
Related Report
Peer Reviewed
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[Journal Article] Evidence for activation of toll-like receptor and receptor for advanced glycation end products in preterm birth2010
Author(s)
Noguchi T, Sado T, Naruse K, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Nagai A, Tanase Y, Yoshida S, Kitanaka T, Oi H, Kobayashi H
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Journal Title
Mediators Inflamm
Volume: 2010
Pages: 1-10
Related Report
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[Journal Article] Anti-inflammatory actions of serine protease inhibitors containing the Kunitz domain.2010
Author(s)
Shigetomi H, Onogi A, Kajiwara H, Yoshida S, Furukawa N, Haruta S, Tanase Y, Kanayama S, Noguchi T, Yamada Y, Oi H, Kobayashi H.
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Journal Title
Inflamm Res.
Volume: 59
Pages: 679-687
Related Report
Peer Reviewed
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[Journal Article] Evidence for activation of Toll-like receptor and receptor for advanced glycation end products in preterm birth2010
Author(s)
Noguchi T, Sado T, Naruse K, Shigetomi H, Onogi A, Haruta S, Kawaguchi R, Nagai A, Tanase Y, Yoshida S, Kitanaka T, Oi H, Kobayashi H.
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Journal Title
Mediators Inflamm.
Volume: 2010
Pages: 490406-490406
Related Report
Peer Reviewed
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[Journal Article] 胎児治療を行った重症RhE不敵合妊娠による新生児容血性疾患の1例2010
Author(s)
武山雅博, 藤田百合, 内田賀子, 柴田真理, 釜本智之, 新居育世, 井崎和史, 西久保敏也, 佐道俊幸, 赤坂珠理晃, 小林浩, 西田幸世, 松本正則, 藤村吉博, 高橋幸博
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Journal Title
日本産婦人科・新生児血液学会誌
Volume: 19
Pages: 51-55
Related Report
Peer Reviewed
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[Presentation] 登録された羊水塞栓症例における症状別解析より本症の発症原因を探る2012
Author(s)
大井豪一,佐道俊幸, 野口武俊, 金山清二, 成瀬勝彦, 常見泰平, 小山恵美, 小池奈月, 小川憲二,河原直紀,小林 浩,金山尚裕
Organizer
第64回日本産科婦人科学会学術講演会
Related Report
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[Presentation] 致死的因子を含む割合が関連する羊水塞栓症における死亡率2011
Author(s)
大井豪一, 佐道俊幸, 野口武俊, 成瀬勝彦, 大野木 輝, 常見泰平, 西岡和弘、岩井加奈, 山田有紀, 小林 浩, 木村 聡, 金山尚裕
Organizer
第63回日本産科婦人科学会総会学術講演会
Place of Presentation
大阪
Related Report
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[Presentation] HYPOXIA DECREASES MATRIX MEETALLOPROTEINASE(MMP)-2 ACTIVATION WITHOUT INCREASING HYPOXIA INDUCED FACTOR(HIF)-1ALPHA IN HUMAN TROPHOBLAST2011
Author(s)
Tsunemi T, Onogi A, Naruse K, Akasaki M, Sado T, Noguchi T, Yamada Y, Oi H, Kobayashi H
Organizer
international Federation of Placenta Associations Meeting 2011(IFPA)
Place of Presentation
Thon Hotel Highland, Lienvegen 11 Geilo, Norway
Related Report
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[Presentation] 選択的帝王切開の至適分娩時期の検討2011
Author(s)
常見泰平, 佐道俊幸, 新納恵美子, 森岡佐知子, 小山恵美, 西岡和弘, 成瀬勝彦, 野口武俊, 大井豪一, 小林浩
Organizer
近畿産科婦人科学会学術集会
Place of Presentation
和歌山・ホテルアバローム紀の国
Related Report
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[Presentation] Correlation of free fatty acid and adiponectin in hypertensive pregnancy:key molecules for homeostatic inflammatory linkage2010
Author(s)
Naruse K, Onogi A, Sado T, Noguchi T, Komeda S, Koyama E, Nishioka K, Kitanaka T, Oi H, Kobayashi H
Organizer
17th World congress of the International Society for the Study of Hypertension in Pregnancy (ISSHP)
Place of Presentation
Melbourne, Australia
Related Report
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