Preparation of the guideline for biomarkers-based personlized treatment for patients with advanced lung cancer
Project/Area Number |
25462179
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Respiratory surgery
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Research Institution | Kagawa University |
Principal Investigator |
Liu Dage 香川大学, 医学部, 助教 (30314941)
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Co-Investigator(Kenkyū-buntansha) |
Nakano Jun 香川大学, 医学部, 助教 (80437673)
Tokunaga Masayosi 香川大学, 医学部付属病院, 助教 (20635825)
Yokomise Hiroyasu 香川大学, 医学部, 教授 (80231728)
Ueno Masaki 香川大学, 医学部, 教授 (30322267)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | バイオマーカー / 進行期肺癌 / 個別化治療 / 化学療法 / 抗癌剤耐性 / ガイドライン作成 |
Outline of Final Research Achievements |
Tailor-made medicine is important for improving the result of cancer treatment. Cancer related biomarkers were comprehensively analysied and biomarkers-based chemotherapy were used into the clinical management in our institude. We tried to establish a simple and standardized [biomarkers-bassed ailor-made medicine selectting system] for widespreading the benefit of biomarkers. The in vitro 3D drug sensitivity test (CD-DST method) and prespective study were performed to verification of the value of biomarkers. These results of our study have been adopted by domestic and international conferences, and the usefness of biomarkers-bassed ailor-made medicine for patients with advanced-stage lung cancer was appealled abroad.
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Report
(3 results)
Research Products
(13 results)
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[Presentation] Verification of biomarkers in predicting drug sensitivity with in vitro 3D drug sensitivity test in non- small cell lung cancer2016
Author(s)
Dage Liu, Nariyasu Nakashima, Yoshuke Kita, Yoshimasa Tokunaga, Kazuhito Nii, Natsumi Matsuura, Jun Nakano, Shintaro Tarumi, Masaya Okuda, Tetsuhiko Go, Xia Zhang, Yoshiyuki Kakehi, Hiroyasu Yokomise
Organizer
第52回米国癌治療学会議 ASCO 2016 Annual Meeting
Place of Presentation
Chicago, USA
Year and Date
2016-06-02
Related Report
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[Presentation] Correlation among the biomarkers for Oral anti-cancer agents in lung adenocarcinoma2016
Author(s)
Nariyasu Nakashima, Dage Liu, Yoshuke Kita, Yoshimasa Tokunaga, Kazuhito Nii, Natsumi Matsuura, Jun Nakano, Shintaro Tarumi, Masaya Okuda, Tetsuhiko Go, Xia Zhang, Yoshiyuki Kakehi, Hiroyasu Yokomise
Organizer
第52回米国癌治療学会議 ASCO 2016 Annual Meeting
Place of Presentation
Chicago, USA
Year and Date
2016-06-02
Related Report
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[Presentation] 肺腺癌における経口型治療薬のバイオマーカー測定は新しい肺癌治療の指標となりうる?2016
Author(s)
中島成泰, 劉 大革, 池田敏裕, 横田 直哉, , 喜田 裕介, 藤原 敦史, 徳永 義昌,新居 和人, 松浦 奈都美, 垂水晋太郎, 奥田 昌也, 中野 淳, 呉 哲彦, 横見瀬 裕保
Organizer
第116回日本外科学会
Place of Presentation
大阪国際会議場
Year and Date
2016-04-14
Related Report
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[Presentation] RRM1抑制アデノウイルスベクターを用いた癌遺伝子治療の基礎的研究2015
Author(s)
徳永 義昌, 劉 大革, 新居 和人, 中野 淳, 池田 敏裕, 喜田 裕介, 横田 直哉, 藤原 敦史, 松浦 奈都美, 笠井 由隆, 奥田 昌也, 後藤 正司, 呉 哲彦, 横見瀬 裕保
Organizer
第56回日本肺癌学会学術集会
Place of Presentation
パシフィコ横浜
Year and Date
2015-11-26
Related Report
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[Presentation] 蛋白バイオマーカーステータスに基づく3期術後補助化学療法の検討2013
Author(s)
奥田 昌也, 伊藤 公一,加藤 歩, 徳永 義昌, 笠井 由隆, 松浦 奈都美, 中野 淳, 後藤 正司, 劉 大革, 呉 哲彦, 横見瀬 裕保
Organizer
第66回日本胸部外科学会定期学術集会
Place of Presentation
仙台(国際センター)
Related Report
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