Issue 87, 2013

Coupling reaction of thioamides with sulfonyl azides: an efficient catalyst-free click-type ligation under mild conditions

Abstract

We report a coupling reaction of thioamides and sulfonyl azides to generate sulfonyl amidines in the absence of any activation additives. The reaction progresses in various solvents under mild conditions. Water exhibits the highest performance with respect to efficiency.

Graphical abstract: Coupling reaction of thioamides with sulfonyl azides: an efficient catalyst-free click-type ligation under mild conditions

Supplementary files

Article information

Article type
Communication
Submitted
08 Aug 2013
Accepted
10 Sep 2013
First published
10 Sep 2013

Chem. Commun., 2013,49, 10242-10244

Coupling reaction of thioamides with sulfonyl azides: an efficient catalyst-free click-type ligation under mild conditions

M. Aswad, J. Chiba, T. Tomohiro and Y. Hatanaka, Chem. Commun., 2013, 49, 10242 DOI: 10.1039/C3CC46055J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements