Critical role of a methyl group on the γ-lactone ring of annonaceous acetogenins in the potent inhibition of mitochondrial complex I
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Acknowledgments
This study was supported in part by a Grant-in-Aid for Young Scientists (B) [Grant 23790130 to N.K.], a Grant-in-Aid for Scientific Research (B) [Grant 22390021 to T.T., Grant 23380064 to H.M.] from the Japan Society for the Promotion of Sciences (JSPS), and the MEXT (the Ministry of Education, Culture, Sports, Science and Technology, Japan)-Supported Program for the Strategic Research Foundation at Private Universities, 2008–2012. We are indebted to Ms. Natsuki Sawada of our laboratory for her
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