Relationship between heart failure and systemic inflammatory disease chronic obstructive pulmonary disease and clarification of vicious cycle factor
Project/Area Number |
15K09090
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Cardiovascular medicine
|
Research Institution | Fukushima Medical University |
Principal Investigator |
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
Keywords | 心不全 / 慢性閉塞性肺疾患 / 全身性炎症疾患 / 肺高血圧症 / 悪液質 |
Outline of Final Research Achievements |
Chronic obstructive pulmonary disease (COPD) has a great influence on cardiovascular diseases. It has been reported that the prognosis of heart failure patients is markedly reduced by the COPD, but there are many uncertainties about the details of the vicious circle. We examined the effects of COPD on cardiac function using samples obtained from patients with heart failure combined with COPD using echocardiography and biomarkers. We clarified that pulmonary hypertension is complicated irrespective of degree of respiratory dysfunction. In addition, since heart failure and COPD are frequent in elderly people and are often in cachectic state, we also examined the relationship with nutritional indicators and clarified the relevance.
|
Report
(4 results)
Research Products
(28 results)
-
[Journal Article] Novel parameter to predict left ventricular filling pressure: product of log B-Type Natriuretic peptide and ratio of mitral inflow early and late diastolic filling velocities.2018
Author(s)
Oikawa M, Kobayashi A, Wada K, Sato T, Suzuki S, Yoshihisa A, Nakazato K, Suzuki H, Saitoh S, Ishida T, Takeishi Y
-
Journal Title
J Card Fail
Volume: 24
Issue: 1
Pages: 29-32
DOI
Related Report
Peer Reviewed / Open Access
-
[Journal Article] Subclinical hypothyroidism is associated with adverse prognosis in heart failure patients.2018
Author(s)
Sato Y, Yoshihisa A, Kimishima Y, Kiko T, Watanabe S, Kanno Y, Abe S, Miyata M, Sato T, Suzuki S, Oikawa M, Kobayashi A, Yamaki T, Kunii H, Nakazato K, Ishida T, Takeishi Y
-
Journal Title
Can J Cardiol
Volume: 34
Issue: 1
Pages: 80-87
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
[Journal Article] Clinical features in extremely elderly patients with heart failure.2017
Author(s)
Yokokawa T, Yoshihisa A, Kanno Y, Sato T, Suzuki S, Misaka T, Oikawa M, Kobayashi A, Yamaki T, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
-
Journal Title
Geriatrics & Gerontology International
Volume: 17
Issue: 11
Pages: 2194-2199
DOI
Related Report
Peer Reviewed
-
-
[Journal Article] Familial hypertrophic obstructive cardiomyopathy with the GLA E66Q mutation and Zebra body2016
Author(s)
Oikawa M, Sakamoto N, Kobayashi A, Suzuki A, Yoshihisa A. Yamaki T, Nakazato K, Suzuki H, Saitoh S, Kiko Y, Nakano H, Hayashi T, Kimura A, Takeishi Y
-
Journal Title
BMC Cardiovasc Disord.
Volume: 16
Issue: 1
Pages: 83-83
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
[Journal Article] Impact of Peripheral Artery Disease on Prognosis in Hospitalized Heart Failure Patients2015
Author(s)
Nakamura Y, Kunii H, Yoshihisa A, Takiguchi M, Shimizu T, Yamauchi H, Iwaya S, Owada T, Abe S, Sato T, Suzuki S, Oikawa M, Kobayashi A, Yamaki T, Sugimoto K, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
-
Journal Title
Circulation Journal
Volume: 79
Issue: 4
Pages: 785-793
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
[Journal Article] Beneficial effects of positive airway pressure therapy for sleep-disordered breathing in heart failure patients with preserved left ventricular ejection fraction2015
Author(s)
Yoshihisa A, Suzuki S, Yamauchi H, Sato T, Oikawa M, Kobayashi A, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
-
Journal Title
Clinical Cardiology
Volume: 38
Issue: 7
Pages: 413-421
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
[Presentation] Association between sleep disordered breathing and arterial stiffness in heart failure patients with reduced or preserved ejection fraction.2016
Author(s)
Satoshi Suzuki, Akiomi Yoshihisa, Yu Sato, Tetsuro Yokokawa, Shunsuke Miura, Takamasa Sato, Shunsuke Watanabe, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Shu-ichi Saitoh, Yasuchika Takeishi.
Organizer
Scientific Sessions of American Heart Association 2016
Place of Presentation
New Orleans
Year and Date
2016-11-12
Related Report
-
[Presentation] Associations between acylcarnitine to total carnitine ratio and adverse prognosis in heart failure patients with reduced or preserved ejection fraction.2016
Author(s)
Shunsuke Watanabe, Akiomi Yoshihisa, Yu Sato, Tetsuro Yokokawa, Shunsuke Miura, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Shu-ichi Saitoh, Yasuchika Takeishi.
Organizer
Scientific Sessions of American Heart Association 2016
Place of Presentation
New Orleans
Year and Date
2016-11-12
Related Report
-
-
-
-
[Presentation] The product value of E/E´ and E/A is a novel prognostic index in patients with non-ischemic cardiomyopathy2016
Author(s)
Oikawa M, Kobayashi A, Yoshihisa A, Suzuki S, Satoh T, Sakamoto N, Yamaki T, Kunii H, Nakazato K, Saitoh S, Takeishi Y
Organizer
第80回 日本循環器学会学術集会
Place of Presentation
仙台
Year and Date
2016-03-18
Related Report
-
-
-
-
-
-
-
[Presentation] Impact of hypocalcemia on mortality of patients with heart failure and chronic kidney disease2015
Author(s)
Miura S, Yoshihisa A, Takiguchi M, Shimizu T, Nakamura Y, Yamauchi H, Owada T, Abe S, Suzuki S, Oikawa M, Kobayashi A, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
Organizer
第79回 日本循環器学会学術集会
Place of Presentation
大阪
Year and Date
2015-04-24
Related Report
-
[Presentation] Impact of body mass index on mortality in heart failure patients2015
Author(s)
Takiguchi M, Yoshihisa A, Miura S, Shimizu T, Nakamura Y, Yamauchi H, Owada T, Abe S, Suzuki S, Oikawa M, Kobayashi A, Sugimoto K, Yamaki T, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
Organizer
第79回 日本循環器学会学術集会
Place of Presentation
大阪
Year and Date
2015-04-24
Related Report
-
[Presentation] Impact of insomnia on prognosis in hospitalized heart failure patients2015
Author(s)
Takiguchi M, Yoshihisa A, Miura S, Shimizu T, Nakamura Y, Yamauchi H, Owada T, Abe S, Suzuki S, Oikawa M, Kobayashi A, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y
Organizer
第79回 日本循環器学会学術集会
Place of Presentation
大阪
Year and Date
2015-04-24
Related Report