Identification and functional analysis of novel hypothalamic neuropeptides involved in energy homeostasis.
Project/Area Number |
21770079
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Animal physiology/Animal behavior
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Research Institution | Hiroshima University |
Principal Investigator |
IWAKOSHI Eiko 広島大学, 大学院・総合科学研究科, 研究員 (50311296)
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Project Period (FY) |
2009 – 2011
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Project Status |
Completed (Fiscal Year 2011)
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Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | 神経ペプチド / 鳥類 / 視床下部 / 摂食行動 / 新規遺伝子 / 組換えタンパク質 / 形態解析 / 生理作用 / 受容体 / 摂食中枢 / 質量分析 |
Research Abstract |
Recently, many neuropeptides involved in food intake have been identified in mammals and extensive studies have been performed to reveal their physiological functions. However, there are little studies on these neuropeptides in non-mammals. In this study, firstly we sought the novel RFamide peptide, 26RFa, in the avian species, as the aspect of energy homeostasis. In addition, we further investigated a novel precursor gene encoding neuropeptide which we have originally identified in the avian brain.
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Report
(4 results)
Research Products
(16 results)
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[Journal Article] Identification, localization, and function of anovel avian hypothalamic neuropeptide, 26RFa, and its cognate receptor, Gprotein-coupled receptor-1032010
Author(s)
Ukena K, Tachibana T, Iwakoshi-Ukena E, Saito Y, Minakata H, Kawaguchi R, Osugi T, Tobari Y, Leprince J, Vaudry H, Tsutsui K.
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Journal Title
Endocrinology
Volume: 151
Pages: 2255-2264
Related Report
Peer Reviewed
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