Application of calcium phosphate cement containing bioactive glasses for endodontic therapy
Project/Area Number |
20592248
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Conservative dentistry
|
Research Institution | Fukuoka Dental College |
Principal Investigator |
IZUMI Toshio Fukuoka Dental College, 歯学部, 准教授 (40248547)
|
Co-Investigator(Kenkyū-buntansha) |
ANAN Hisashi 福岡歯科大学, 歯学部, 教授 (80158732)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2010: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2008: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | リン酸カルシウムセメント / bioactive glass / 覆髄材 / 骨補填材 / Bioactive glass / apoptosis / 大食球 |
Research Abstract |
The dentin bridge formation was observed when a new calcium phosphate cement (CPC) that contained bioactive glasses was used as a pulp capping agent. And there was no significant difference in the ability of dentin bridge formation between the new CPC and a calcium hydroxide. Some apoptic cells were observed in the pulp during dentin bridge formation. It was suggested that about 60% of apoptic cells should be monocytes/macrophages, which contained TUNEL+ nucleus, and the rest should be pulp cells. The new CPC did not make a significant difference in the new bone formation compared with hydroxyapatite as a bone grafting material.
|
Report
(4 results)
Research Products
(3 results)