Issue 16, 2015

Hydration of nitriles to amides by a chitin-supported ruthenium catalyst

Abstract

Chitin-supported ruthenium (Ru/chitin) promotes the hydration of nitriles to carboxamides under aqueous conditions. The nitrile hydration can be performed on a gram-scale and is compatible with the presence of various functional groups including olefins, aldehydes, carboxylic esters and nitro and benzyloxycarbonyl groups. The Ru/chitin catalyst is easily prepared from commercially available chitin, ruthenium(III) chloride and sodium borohydride. Analysis of Ru/chitin by high-resolution transmission electron microscopy indicates the presence of ruthenium nanoparticles on the chitin support.

Graphical abstract: Hydration of nitriles to amides by a chitin-supported ruthenium catalyst

Supplementary files

Article information

Article type
Paper
Submitted
03 Dec 2014
Accepted
05 Jan 2015
First published
08 Jan 2015
This article is Open Access
Creative Commons BY license

RSC Adv., 2015,5, 12152-12160

Hydration of nitriles to amides by a chitin-supported ruthenium catalyst

A. Matsuoka, T. Isogawa, Y. Morioka, B. R. Knappett, A. E. H. Wheatley, S. Saito and H. Naka, RSC Adv., 2015, 5, 12152 DOI: 10.1039/C4RA15682J

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