Rchr
J-GLOBAL ID:201301028145220311
Update date: Apr. 13, 2023
Yoshikuni Goto
ゴトウ ヨシクニ | Yoshikuni Goto
Contact this researcher
You can send email directly to the researcher.
Affiliation and department:
Teikyo Heisei University Faculty of Pharmaceutical Sciences
About Teikyo Heisei University Faculty of Pharmaceutical Sciences
Search "Teikyo Heisei University Faculty of Pharmaceutical Sciences"
Detailed information
Homepage URL (1):
http://kaken.nii.ac.jp/d/r/90455345.ja.html
Research field (3):
Pathobiochemistry
, Pharmaceuticals - health and biochemistry
, Applied biochemistry
Research keywords (14):
エキソソーム
, セロトニン
, 不安障害
, アミノペプチダーゼ
, 血圧調節
, インターフェロン
, LPS
, 分泌
, 貪食
, マクロファージ
, リポ多糖
, 一酸化窒素
, 一塩基多型
, 基質特異性
Research theme for competitive and other funds (12):
2022 - 2025 MHCクラスI抗原提示の機能不全が惹起する脳内セロトニン過剰疾患「不安障害」
2019 - 2022 Dysfunction of ERAP1 induces anxiety disorder via excess serotonin synthesis
2016 - 2019 Mechanism of mucosal immunity activation by exosome
2016 - 2019 Roles of ER aminopeptidase 1 in inflammation of Behcet's disease
2015 - 2017 Role of ERAP1 in the pathogenesis of mental disorders
2013 - 2016 Molecular mechanism and regulation of immune activation cascade by aminopeptidase contained exosome.
2013 - 2016 Pathophysiological roles of M1 aminopeptidases
2012 - 2015 Contribution of ER-aminopeptidase secretion to classical activation of macrophages
2012 - 2014 Role of aminopeptidases in atherosclerosis
2009 - 2011 Regulation of blood pressure by secreted adipocyte-derived leucine aminopeptidase
2006 - 2008 Mechanisms of Enzymatic Action of the Oxytocinase Subfamily of Aminopeptidases
2008 - 脂肪細胞由来ロイシンアミノペプチダーゼの分泌を介した新規血圧調節作用の機構解明と高血圧療法への応用
Show all
Papers (28):
Rena Shiraishi, Satomi Morita, Yoshikuni Goto, Yasushi Mizoguchi, Wataru Nakamura, Takahiro J. Nakamura. Diurnal variations of triglyceride accumulation in mouse and bovine adipocyte-derived cell lines. Animal Science Journal. 2022. 93. 1. e13802
Yuko Ogawa, Yoshihiro Akimoto, Mamoru Ikemoto, Yoshikuni Goto, Anna Ishikawa, Sakura Ohta, Yumi Takase, Hayato Kawakami, Masafumi Tsujimoto, Ryohei Yanoshita. Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions. Biochemistry and biophysics reports. 2021. 27. 101034-101034
Masafumi Tsujimoto, Kazuma Aoki, Yoshikuni Goto, Atsushi Ohnishi. Molecular and functional diversity of the oxytocinase subfamily of M1 aminopeptidases. Journal of biochemistry. 2021. 169. 4. 409-420
Yoshikuni Goto, Takahiro J Nakamura, Kenji Ogawa, Akira Hattori, Masafumi Tsujimoto. Reciprocal Expression Patterns of Placental Leucine Aminopeptidase/Insulin-Regulated Aminopeptidase and Vasopressin in the Murine Brain. Frontiers in molecular biosciences. 2020. 7. 168-168
Masafumi Tsujimoto, Kazuma Aoki, Atsushi Ohnishi, Yoshikuni Goto. Endoplasmic Reticulum Aminopeptidase 1 beyond Antigenic Peptide-Processing Enzyme in the Endoplasmic Reticulum. Biological & pharmaceutical bulletin. 2020. 43. 2. 207-214
more...
MISC (41):
後藤芳邦, 津元裕樹, 三浦ゆり, 遠藤玉夫, 野元裕, 辻本雅文, 中西雅之. Activation of macrophages by variant surface glycoprotein from Trypanosoma brucei in vitro. 日本寄生虫学会大会プログラム・抄録集. 2020. 89th
辻本雅文, 青木一真, 大西敦, 後藤芳邦. 多機能性酵素としての小胞体アミノペプチダーゼ-ERAP研究の20年-. 生化学. 2019. 91. 5. 666-680
小林春奈, 後藤芳邦, 中村孝博, 小川健司, 服部明, 辻本雅文. 小胞体アミノペプチダーゼ1遺伝子欠損はセロトニン合成亢進を介して不安障害を惹起する. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
小島雄太郎, 後藤芳邦, 中村孝博, 辻本雅文. バソプレシン分解酵素P-LAPの脳内局在と概日リズム. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
斎藤朱里, 後藤芳邦, 中村孝博, 小川健司, 服部明, 辻本雅文. 小胞体アミノペプチダーゼ1遺伝子欠損は,セロトニン合成を亢進することで不安を誘発する. 日本生化学会大会(Web). 2019. 92nd
more...
Education (1):
2004 - 2007 Tokyo University of Agriculture and Technology United Graduate School of Agricultural Science Department of Biochemistry and Biotechnology
Professional career (1):
博士(農学) (東京農工大学大学院)
Work history (4):
2016/04 - 現在 Teikyo Heisei University Faculty of Pharmaceutical Sciences
2014/04 - 2016/03 Teikyo Heisei University Faculty of Pharmaceutical Sciences
2010/04 - 2014/03 Teikyo Heisei University Faculty of Pharmaceutical Sciences
2007/04 - 2010/03 理化学研究所 細胞生化学研究室 基礎科学特別研究員
Awards (1):
2010/08 - 病態プロテアーゼ学会 第14回日本病態プロテアーゼ学会学術集会 学会奨励賞 マクロファージにおける脂肪細胞由来ロイシンアミノペプチダーゼの分泌機構
Association Membership(s) (3):
THE JAPANESE BIOCHEMICAL SOCIETY
, 日本寄生虫学会
, 日本薬学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in
researchmap
.
For details, see here
.
Return to Previous Page
TOP
BOTTOM