書誌事項
- タイトル別名
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- Development of Multifunctional Envelope Type Artificial Viral like Gene Delivery System
- タキノウセイ エンベロープガタ ジンコウ イデンシ デリバリー システム ノ ソウセイ
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抄録
This review introduces a new concept “Programmed Packaging” to develop a non-viral gene delivery system. Based on this concept, multifunctional envelope type nano devices (MEND) were developed for in vitro, in situ and in vivo conditions. A quantitative study to identify a rate limiting step in intracellular trafficking was also shown between viral and non-viral vectors, which indicated an important role of controlled intranuclear disposition for development a safe and efficient non-viral gene delivery system. This review will provide a future direction of non-viral gene delivery system.<br>
収録刊行物
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- 薬学雑誌
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薬学雑誌 127 (10), 1655-1672, 2007-10-01
公益社団法人 日本薬学会
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キーワード
詳細情報
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- CRID
- 1390001206127080064
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- NII論文ID
- 110006402950
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 8964578
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可