KAZUSAKA Akio 数坂昭夫

Researcher Number	00002113
Other IDs
Affiliation (based on the past Project Information) *help	1995 – 2003: 北海道大学, 大学院・獣医学研究科, 助教授 1999: 北海道, 大学院・獣医学研究科, 助教授 1997 – 1998: Hokkaido Univ., Grad.Sch.of Vet.Med., Ass.Pro., 大学院獣医学研究科, 助教授 1995: Hokkaido Univ., Graduate School of Veterinary Medicine, Assoc. Pro., 大学院獣医学研究科, 助教授 1992 – 1994: 北海道大学, 獣医学部, 助教授 1989: HOKKAIDO UNIVERSITY, FACULTY OF VETERINARY MEDICINE, ASSOCIATE PROFESSOR, 獣医学部, 助教授 1988: 北海道大学, 触媒研究所, 助教授
Review Section/Research Field	Principal Investigator Applied veterinary science / Biomedical engineering/Biological material science / Public health/Health science / 環境保全 / 工業物理化学 Except Principal Investigator Applied veterinary science / Science and Engineering / Laboratory animal science / 環境影響評価(含放射線生物学) / Measurement engineering / Risk sciences of radiation/Chemicals / Measurement engineering
Keywords	Principal Investigator レゾルフィン / 光ファイバ形センサ装置 / 蛍光測定 / 化学発癌 / チトクロムP-450の誘導 / マウス / Wistarラット / エトキシレゾルフィン / ユリ / P450-1A1分子種 … More / 狂牛病 / プリオン・タンパク / 光ファイバーセンシング・システム / 抗体固定化光ファイバの作成 / 金微粒子 / Surface enhanced ramanスペクトル / 銀微粒子 / プリオン / モデルペプチド / Cu(II)イオン / 蛍光分光法 / ESR / 活性酸素生成能 / 紫外光による環境毒性 / オゾン層 / 葉緑体 / クロロフィル / 一重項酸素 / クロロフィルの蛍光スペクトル / チラコイド膜の過酸化反応 / プロテアーゼの誘導 / 植物葉緑体 / クロロフィル類 / イソフラボングルコサイドの蓄積 / 穀物種子 / エリシター活性の誘導 / Echotoxicology / Stratospheric ozone / Chloroplast / Chlorophyll / Singlet oxygen / Luminescence spectrum of chlorophyll / Peroxidation of thyrakoid membrane / Induction of protease / 毒性試験 / 動物代替毒性試験法 / チトクロムP450 / 酵素機能解析 / 分子生物学的手法 / 分光学的手法 / 非侵襲 / 遺伝子組み替え / CYPIID / イヌCYPII D15 / 海棲哺乳動物CYP1A / Sf9細胞 / チトクロムP450IID / イヌP450IID15 / バキュロウイルス / P450酵素反応 / P450-2D / 組み替えP450の発現 / 光ファイバー検出系 / P450-1A / エトキシゾルフィン / TOXICOLOGICAL ASSESSMENT / ANIMAL SUBSTITUTION / CYTOCHROME P450 / ENZYMATIC ANALYSIS / MOLECULAR BIOLOGICAL METHOD / SPECTROSCOPIC METHOD / NONINVASIVE ASSESSMENT / ゴマフアザラシ / クラカケアザラシ / 有機塩素化合物 / 肝P450 / 甲状腺機能 / サイロキシン / サイロニン / 内分泌攪乱物質 / トリブチルスズ / ビスフェノール A / ラット / 中枢神経系 / 精巣上体の発育不良 / 血中チロキシン濃度の低下 / 海棲哺乳動物 / チトクロームP450 / 環境汚染 / ゴマアザラシ / 水棲哺乳動物 / 異物代謝酵素 / 複合汚染 / largha seals / ribbon seals / chlorinated hydrocarbon / cytochrome P450 in liver / thyroid function / thyroxine / thyronine / シリカ担持銅触媒 / 酢酸銅 / 固定化銅錯体 / 銅-酸素錯体 / モリブデン触媒 / モリブドケイ酸 / 固定化錯体電極 / 炭酸ガスの還元 / シリカ担持コバルト触媒 / 炭酸ガスのメタン化反応 / 固定化コバルト・ポルフィリン錯体電極 / 炭酸ガスの電解還元 / 高温焼成セリウム複合酸化物 / イットリビウムの添加効果 / メタン酸化カップリング反応 / 固定化銅ビリジン錯体 / 銅酸素錯体 / フエノールの酸化重合反応 / シリカ担持モリブデン触媒の光還元 / シリカ担持モリブデン触媒上のゼロ価モリブデン種 / シリカ担持モリブデン触媒の固体酸性の発現 / Silica-supported catalyst / Cupric acetate / Fixed copper complex / Copper-oxygen adducts / Molybdenum catalyst / Molybdosilic acid / Fixed complex electrode / Reduction of carbon dioxide … More Except Principal Investigator 環境汚染 / P450 / CYP1A1 / シトクロムP450 / ビスフェノールA / ステロイドホルモン / 環境ホルモン / CYP2D / cytochrome P450 / 異物代謝酵素CYP / ゴマフアザラシ / クラカケアザラシ / フタル酸エステル / PPAR / CYP1A / ダイオキシン受容体 / Cytochrome P450 / 海棲哺乳動物 / 生物濃縮 / 環境汚染モニター / 内分泌撹乱物質 / アロマターゼ活性 / ドブネズミ / 海棲哺乳類 / ダイオキシン類 / 野生動物 / バイオマーカー / 甲状腺ホルモン / エストロゲン / ベンゾピレン / オオワシ / オジロワシ / コイ / 二次卵母細胞 / CYP2B / wild life / endocrine disrupting chemicals / 環境汚染物質 / steroid hormone / environmental pollution / チトクロムP450 / 光ファイバセンサ / 肝臓 / トリブチルスズ化合物 / GFAP / イルカ / クジラ / アザラシ / 複合汚染 / 有機塩素化合物 / 有機スズ化合物 / ダイオキシン / 免疫 / Ahレセプター / TCDD / レチノイン酸 / ラット / エステロゲンレセプター / P450 19 / フタル酸ジブチル / アンドロステンジオン / 陸生哺乳類 / 精巣 / 哺乳類 / PCB / 異物代謝 / イヌ / クマ / キツネ / ミンク / 植物葉緑体 / シングレットオキシジェン / モクズガニ / P-450 / 環境評価 / P-4502Dサブファミリー / 動物種差 / 解毒酵素 / 老化 / 発癌 / 発生動物 / Environment / Metabolism / Wild animals / Mink / Dogs / Bears / 薬物代謝多形 / エゾヤチネズミ / モデル動物 / シトロクロムP450 / CYP2D1 / CYP2D2 / 薬物副作用 / DAラット / CYP3A / 薬物代謝 / 多形 / 環境要因 / polymorphic drug metabolism / Clethrionomys rufocanus / model animals / 魚食性 / バイオマーカ / Chlorinated hydrocarbon / tri-butyltin / fish-eating / Steroid hormone / organochlorine / 環境汚染評価 / バイオリメディエーション / Ah受容体 / biomarker / dioxin / 代謝酵素 / 発癌物質 / 癌発症機構 / プラスチック光ファイバ / 発ガン酵素 / 蛍光分折法 / 発ガン機構 / Metabolism enzyme / Optical fiber sensor / Carcinogen / cancer mechanism / Plastic optical fiber / マイクロアレイ / 核内受容体 / DNAマイクロアレイ / arylhydrocarbon receptor / 臭素化難燃剤 / microarray / wildlife / nuclear receptor / aryl hydrocarbon receptor / 光ファイバ・バイオセンサ / 癌診断 / 発癌促進酵素 / EROD / ethoxyresorufin / optical fiber sensor / optical-bio-sensor / cancer diagnositcs / cancer initiation enzyme Less

Development of Environmental Risk Assessment System
- Principal Investigator
  
  FUJITA Shoichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hokkaido University
Development of a quick in -vivo sensing system based on fiber-optics for cancer diagnostics at very early stage
- Principal Investigator
  
  SASAKI Issei
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Measurement engineering
- Research Institution
  Hokkaido Institute of Technology
狂牛病原因物質プリオン・モデルペプチドの変成機序に関する分光学的研究Principal Investigator
- Principal Investigator
  
  数坂昭夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  Hokkaido University
哺乳類の生殖および行動異常の現状と汚染の関係
- Principal Investigator
  
  藤田正一
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
フタル酸エステルによる内分泌撹乱機構の解明
- Principal Investigator
  
  藤田正一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
The effects of endocrine disrupting chemicals on wildlife
- Principal Investigator
  
  FUJITA Shoichi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
The risk assessment and clarification of endocrine disrupting chemicals in environment. Use of P450 for the biomonitoring and bioremediation of environmental pollution-
- Principal Investigator
  
  FUJITA Shoichi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Hokkaido University
Optical fiber sensor system development and its application to research of cancer development
- Principal Investigator
  
  SASAKI Issei
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Measurement engineering
- Research Institution
  Hokkaido Institute of Technology
水棲哺乳動物における複合汚染状況を考慮した生体毒性学的研究 -環境汚染物質の生体内相互作用-Principal Investigator
- Principal Investigator
  
  数坂昭夫, IWATA Hisato
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
環境中ダイオキシンによる免疫抑制機構の解明
- Principal Investigator
  
  藤田正一
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
癌予防を目指す関連チトクロムP450の検出フォトダイナミック診断法の基礎研究Principal Investigator
- Principal Investigator
  
  数坂昭夫
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Hokkaido University
Development of assessment method for complex aquatic pollution using xenobiotic metabolic enzyme in liver of aquatic mammalsPrincipal Investigator
- Principal Investigator
  
  KAZUSAKA Akio, 岩田久人
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Applied veterinary science
- Research Institution
  HOKKAIDO UNIVERSITY
DEVELOPMENT OF CYTOCHROME P-450 PROCESS FOR THE STUDY OF TOXICOLOGY WITHOUT USING ANIMALSPrincipal Investigator
- Principal Investigator
  
  KAZUSAKA Akio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  HOKKAIDO UNIVERSITY
Establishment of model animals for polymorphic drug metabolism associated with CYP2D
- Principal Investigator
  
  FUJITA Shoichi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  HOKKAIDO UNIVERSITY
ECHOTOXICOLOGY OF ULTRA VIOLET RADIATION ON EARTH ENHANCED BY DEPLETION OF STRATOSPHERIC OZONEPrincipal Investigator
- Principal Investigator
  
  KAZUSAKA Akio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  環境保全
- Research Institution
  HOKKAIDO UNIVERSITY
Toxicological Studies on Species Difference in Metabolic Toxication of Environmental Chamicals-with a Special Focus on Cytochrome P-450
- Principal Investigator
  
  FUJITA Shoichi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Applied veterinary science
- Research Institution
  Faculty of Veterinary Medicine, Hokkaido University
STRUCTURAL AND ELECTRONICAL CONTROL OF METAL IONS SUPPORTED ON OXIDESPrincipal Investigator
- Principal Investigator
  
  KAZUSAKA Akio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  工業物理化学
- Research Institution
  FACULTY OF VETERINARY MEDICINE, HOKKAIDO UNIVERSITY

All 2007 2006 2005 2004 2003

All Journal Article

[Journal Article] Di-(2-ethylhexyl) phthalate suppresses tamoxifen-induced apoptosis in GH3 pituitary cells.2007
- Author(s)
  Kim HS, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Arch Toxicol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications.2006
- Author(s)
  Muzandu K, Ishizuka M, Sakamoto KQ, Shaban Z, El Bohi K, Kazusaka A, Fujita S.
- Journal Title
  
  Toxicol Appl Pharmacol. 215
  
  Pages: 330-340
- NAID
  120000953610
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Induction of cytochrome P450 1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand.2006
- Author(s)
  Jinno, A., Maruyama, Y., Ishizuka, M., Kazusaka, A., Nakamura, A., Fujita, S.
- Journal Title
  
  J.Steroid Biochem.Mol.Biol. 98
  
  Pages: 48-55
- NAID
  120000957462
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] CYP2D-related metabolism in animals of the Canoidea superfamily-species differences.2006
- Author(s)
  Ishizuka M, Lee JJ, Masuda M, Akahori F, Kazusaka A, Fujita S
- Journal Title
  
  Vet Res Commun. 30
  
  Pages: 505-512
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Effect of lycopene and beta-carotene on peroxynitrite-mediated cellular modifications.2006
- Author(s)
  Muzandu K, Ishizuka M, Sakamoto KQ, Shaban Z, El Bohi K, Kazusaka A, Fujita S.
- Journal Title
  
  Toxicol Appl Pharmacol. 215(3)
  
  Pages: 330-40
- NAID
  120000953610
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] CYP2D related metabolism in animals of the Canoidea super family - The species difference.2006
- Author(s)
  Ishizuka, M., Lee, J.J., Masuda, M., Akahori F., Kazusaka A., Fujita, S.
- Journal Title
  
  Vet Res Comm. (in press)
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand.2006
- Author(s)
  Jinno A, Maruyama Y, Ishizuka M, Kazusaka A, Nakamura A, Fujita S.
- Journal Title
  
  J Steroid Biochem Mol Biol. 98(1)
  
  Pages: 48-55
- NAID
  120000957462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Induction of cytochrome P450-1A by the equine estrogen equilenin, a new endogenous aryl hydrocarbon receptor ligand.2006
- Author(s)
  Jinno A, Matuyama Y, Ishizuka M, Kazusaka A, Nakamura A, Fujita S.
- Journal Title
  
  J Steroid Biochem Mol Biol. 98
  
  Pages: 48-55
- NAID
  120000957462
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] CYP2D-related metabolism in animals of the Canoidea superfamily-species differences.2006
- Author(s)
  Ishizuka M, Lee JJ, Masuda M, Akahori F, Kazusaka A, Fujita S.
- Journal Title
  
  Vet Res Commun. 30
  
  Pages: 505-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Nitric oxide enhances catechol estrogen-induced oxidative stress in LNCaP cells.2005
- Author(s)
  Muzandu K, Shaban Z, Ishizuka M, Kazusaka A, Fujito S.
- Journal Title
  
  Free Radio Res. 39
  
  Pages: 389-398
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Effect of components of green tea extracts, caffeine and catechins on hepatic drug metabolizing enzyme activities and mutagenic transformation of carcinogens.2005
- Author(s)
  Nikaidou S, Ishizuka M, Maeda Y, Hara T, Kazusaka A, Fujita S.
- Journal Title
  
  J Vet Med Sci. 67(1)
  
  Pages: 137-138
- NAID
  110004665689
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Antigenotoxic effect of Pleurotus cornucopiae extracts on the mutagenesis of Salmonella typhimurium TA98 elicited by benzo[a]pyrene and oxidative DNA lesions in V79 hamster lung cells.2005
- Author(s)
  El Bohi KM, Sabik L, Muzandu K, Shaban Z, Soliman M, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Jpn J Vet Res. 52(4)
  
  Pages: 163-72
- NAID
  110004665687
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Lycopene and beta-carotene ameliorate catechol estrogen-mediated DNA damage.2005
- Author(s)
  Muzandu K, El Bohi K, Shaban Z, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Jpn J Vet Res. 52(4)
  
  Pages: 173-84
- NAID
  110004665688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Effect of components of green tea extracts, caffeine and catechins on hepatic drug metabolizing enzyme activities and mutagenic transformation of carcinogens.2005
- Author(s)
  Nikaidou S, Ishizuka M, Maeda Y, Hara Y, Kazusaka A, Fujita S.
- Journal Title
  
  Jpn J Vet Res. 52(4)
  
  Pages: 185-92
- NAID
  110004665689
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] AhR and PPARalpha : antagonistic effects on CYP2B and CYP3A, and additive inhibitory effects on CYP2C11.2005
- Author(s)
  Shaban Z, Soliman M, El-Shazly S, El-Bohi K, Abdelazeez A, Kehelo K, Kim HS, Muzandu K, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Xenobiotica. 35
  
  Pages: 51-68
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Importance of CYP2D3 in polymorphism of diazepam p-hydroxylation in rats.2005
- Author(s)
  Sakai N, Saito K, Kim HS, Kazusaka A, Ishizuka M, Funae Y, Fujita S.
- Journal Title
  
  Drug Metab Dispos. 33
  
  Pages: 1657-1660
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Possible involvement of peroxynitrite in estrogen-induced oxidative stress.2005
- Author(s)
  Muzandu K, Shaban Z, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Free Radical Research. 39(4)
  
  Pages: 389-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] AhR and PPARa Antagonistic effects on CYP2B and CYP3A and additive inhibitory effects on CYP2C11.2005
- Author(s)
  Shaban Z, Soliman M, El-shazly S, El-bohi K, Abdelazeez A, Kehelo K, Kim H, Muzandu K, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Xenobiotica. 52(4)
  
  Pages: 163-172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Importance of CYP2D3 in polymorphism of diazepam p-hydroxylation in rats.2005
- Author(s)
  Sakai N, Saito K, Kim HS, Kazusaka A, Ishizuka M, Funae Y, Fujita S.
- Journal Title
  
  Drug Metab Dispos. 2005 33(11)
  
  Pages: 1657-60
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Iodine intake as a possible cause of discontinuous decline in sperm counts : a re-evaluation of historical and geographic variation in semen quality.2004
- Author(s)
  Sakamoto KQ., Ishizuka M., Kazusaka, A., Fujita, S.
- Journal Title
  
  Jpn J Vet Res. 52(2)
  
  Pages: 85-94
- NAID
  110004101389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Down regulation of hepatic PPARalpha function by AhR ligand.2004
- Author(s)
  Shaban, Z., El-Shazly, S., Abdelhady, S., Fattouh, I., Muzandu, K., Ishizuka M., Kimura, K., Kazusaka, A., Fujita, S.
- Journal Title
  
  J Vet Med Sci. 66(11)
  
  Pages: 1377-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] PPARalpha-dependent modulation of hepatic CYP1A by clofibric acid in rats2004
- Author(s)
  Z.Shaban, A.Kazusaka, et al.
- Journal Title
  
  Arch.Toxicol. 78(9)
  
  Pages: 496-507
- Data Source
  KAKENHI-PROJECT-15560362
[Journal Article] Related PPARalpha-dependent modulation of hepatic CYP1A by clofibric acid in rats.2004
- Author(s)
  Shaban Z, El-Shazly S, Ishizuka M, Kimura K, Kazusaka A, Fujita, S.
- Journal Title
  
  Arch Toxicol. 78(9)
  
  Pages: 496-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Polymorphism in diazepam metabolism in Wistar rats.2004
- Author(s)
  Saito K, Kim HS, Sakai N, Ishizuka M, Kazusaka A, Fujita, S.
- Journal Title
  
  J Pharm Sci. 93(5)
  
  Pages: 1271-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Alterations of activities of cytosolic phospholipase A2 and arachidonic acid-metabolizing enzymes in di-(2-ethylhexyl)phthalate-induced testicular atrophy.2004
- Author(s)
  Kim HS, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  J Vet Med Sci. 66(9)
  
  Pages: 1119-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Strain differences in diazepam metabolism at its three metabolic sites in sprague-dawley, brown norway, dark agouti, and wistar strain rats.2004
- Author(s)
  Saito K, Sakai N, Kim HS, Ishizuka M, Kazusaka A, Fujita, S.
- Journal Title
  
  Drug Metab Dispos. 32(9)
  
  Pages: 959-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Short period exposure to di-(2-ethylhexyl)phthalate regulates testosterone metabolism in testis of prepubertal rats2003
- Author(s)
  K.Q.akamoto, A.Kazusaka, et al.
- Journal Title
  
  Arch.Toxicol. 77(8)
  
  Pages: 446-451
- Data Source
  KAKENHI-PROJECT-15560362
[Journal Article] Short period exposure to di-(2-ethylhexyl) phthalate regulates testosterone metabolism in testis of prepubertal rats.2003
- Author(s)
  Kim, HS, Saito K, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Arch Toxicol. 77(8)
  
  Pages: 446-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009
[Journal Article] Cytochrome p450 induction and gonadal status alteration in common carp (Cyprinus carpio) associated with the discharge of dioxin contaminated effluent to the Hikiji River, Kanagawa Prefecture, Japan.2003
- Author(s)
  Sakamoto KQ, Nakai K, Aoto T, Yokoyama A, Ushikoshi R, Hirose H, Ishizuka M, Kazusaka A, Fujita S.
- Journal Title
  
  Chemosphere. 51(6)
  
  Pages: 491-500
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15201009

1. FUJITA Shoichi (10143314)

# of Collaborated Projects: 14 results

# of Collaborated Products: 26 results
2. IWATA Hisato (10271652)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. ISHIZUKA Mayumi (50332474)

# of Collaborated Projects: 5 results

# of Collaborated Products: 27 results
4. SASAKI Issei (00002006)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MASUDA Makihiko (00001719)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HIDENOBU Hoshi (30301188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANABE Shinsuke (60116952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAMOTO Kentaro (80374627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 昆泰寛 (10178402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAZUSAKA Akio 数坂 昭夫

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狂牛病原因物質プリオン・モデルペプチドの変成機序に関する分光学的研究Principal Investigator

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水棲哺乳動物における複合汚染状況を考慮した生体毒性学的研究 -環境汚染物質の生体内相互作用-Principal Investigator

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癌予防を目指す関連チトクロムP450の検出フォトダイナミック診断法の基礎研究Principal Investigator

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Development of assessment method for complex aquatic pollution using xenobiotic metabolic enzyme in liver of aquatic mammalsPrincipal Investigator

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DEVELOPMENT OF CYTOCHROME P-450 PROCESS FOR THE STUDY OF TOXICOLOGY WITHOUT USING ANIMALSPrincipal Investigator

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ECHOTOXICOLOGY OF ULTRA VIOLET RADIATION ON EARTH ENHANCED BY DEPLETION OF STRATOSPHERIC OZONEPrincipal Investigator

KAZUSAKA Akio 数坂昭夫