TAGUCHI Takeo 田口武夫

… Alternative Names

田口武夫タグチタケオ

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Researcher Number	00016180
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2010: 東京薬科大学, 薬学部, 教授 1997 – 2003: 東京薬科大学, 薬学部, 教授 1994 – 1995: 東京薬科大学, 薬学部, 教授 1990: 東京薬科大学, 薬学部, 教授 1986: 東京薬科大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy / Synthetic chemistry Except Principal Investigator Chemical pharmacy
Keywords	Principal Investigator Diels-Alder reaction / フルオロオレフィン / ジフルオロケトン / ラジカル反応 / イミデート転位反応 / Asymmetric synthesis / Glutamic acid / 不斉合成 / グルタミン酸 / ジフルオロシクロプロパン … More / シクロプロパン / 塩化クロム / トリフルオロアセトアルデヒド / トリフルオロメタンスルホニル / ペプチドミメチックス / トリフルオロメチル / ジフルオロメチレン / Atoropisomeric amide / Fluoroacrylate / Trifluoroacetaldehyde / Glutamate receptor / Chromium chloride / Peptidemimetics / Fluorinated olefin / 軸不斉アミド / フルオロビニルエーテル / 軸負不斉ラクタム / ルイス酸 / ジペプチドイソスター / フルオロアリルアルコール / アトロプ異性 / ペプチドミメティックス / アトロプ異性アミド / フルオロアクリル酸エステル / Diels-Alder反応 / グルタミン酸受容体 / Homoally radical / Radical cycloaddition / Cyclopropane derivative / carbocyclization / Dipeptide isostere / Fluorinated olefins / ピロリジン誘導体 / シクロペンタン誘導体 / アミノ酪酸 / シクロプロパン誘導体 / ジルコノセン錯体 / ジペプチド / Atropisomers / lodoaminocyclization / Clasen rearrangement / Methylenecyclopropane / Cyclopropylglycine / Difluorocyclopropane / クライゼン転位反応 / シクロプロピルアニオン / フルオロアクリル酸 / メチレンジフルオロシクロプロパン / 2-フルオロアクリル酸 / ヨードアミノ環化 / ディール・アルダー反応 / クライゼン転位 / メチレンシクロプロパン / シクロプロピルグリシン / Iodine / Zirconium complex / Difluoroketone / Difluorocycloprepane / Cyclopropane / メタノグルタミン酸 / ヨウ素 / ディールス-アルダー反応 / ジルコニウム錯体 / シリルオキシフラン / アミド配座異性 / 向山-マイケル反応 / ブレンステッド酸 / メイケル付加反応 / アルドール反応 / アルキルアルミニウム / 炭素酸 / トリフリル基 / ペプチドイソスター / フルオロアルケン / 有機フッ素化学 / フルオロアルキル / トルフルオロメチル / フッ素化 / フッ素 / ジフルオロリジン / ジフルオログルタミン酸 / ヨ-ドジフルオロ酢酸 / ディ-ルスアルダ-反応 / 2ートリフルオロメチルプロペン酸 / 細胞分化誘導 / ビタミンD_3 … More Except Principal Investigator フェニルスルホン / トリフルオロメチル / カルシウム / フェニルスルホニル / ジフルオロ / トリフルオロ / ビタミン【D_2】 / ビタミン【D_3】 Less

Preparation of functionalized organofluorine compounds toward drug discoveryPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Takeo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of synthetic methodogies for organofluorine compounds in medicinal chemistryPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Takeo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of new synthetic methods for organofluorine compounds of biomedical interestPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Takeo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
フッ素原子による機能の創出Principal Investigator
- Principal Investigator
  
  田口武夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Synthetic chemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of asymmetric synthetic method for organofluorine compounds of biological interestsPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Takeo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Development of New Synthetic Methods for the Preparation of Organic Fluorine Compounds and the Application to Fluorinated Biological SubstancesPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Takeo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo College of Pharmacy
有機フッ素化合物の新合成法の開発と含フッ素生理活性物質合成への応用Principal Investigator
- Principal Investigator
  
  田口武夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
含フッ素活性型ビタミンD⊇の合成研究
- Principal Investigator
  
  小林義郎
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] フッ素化学入門2010基礎と応用の最前線2010
- Author(s)
  田口武夫, 他(分担執筆)
- Total Pages
  537
- Publisher
  三共出版
- Data Source
  KAKENHI-PROJECT-20590013
[Book] Fluorine in Medicinal Chemistry and Chemical Biology2009
- Author(s)
  田口武夫
- Total Pages
  624
- Publisher
  WILEY-BLACKWELL
- Data Source
  KAKENHI-PROJECT-20590013
[Book] Acid Catalysis in Modern Organic Synthesis2008
- Author(s)
  田口武夫
- Total Pages
  1112
- Publisher
  WILEY-VCH
- Data Source
  KAKENHI-PROJECT-17590015
[Book] フッ素系材料の応用技術2006
- Author(s)
  田口武夫(共著)
- Total Pages
  350
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Copper mediated defluorinative allylic alkylation of difluorohomoallyl alcohol derivatives directed to an efficient synthetic method for (Z)-fluoroalkene dipeptide isosteres.2011
- Author(s)
  D.Watanabe, M.Koura, A.Saito, H.Yanai, Y.Nakamura, M.Okada, A.Sato, T.Taguchi
- Journal Title
  
  J.Fluorine Chem. 132
  
  Pages: 327-338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Copper-free defluorinative alkylation of allylic difluorides through Lewis acid-mediated C-F bond activation.2011
- Author(s)
  H.Yanai, H.Okada, A.Sato, M.Okada, T.Taguchi
- Journal Title
  
  Tetrahedron Lett. 52
  
  Pages: 2997-3000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] 1,4-Addition of Silicon Dienoates to α, β-Unsaturated Aldehydes Catalyzed by In situ-generated Silicon Lewis Acid2010
- Author(s)
  H.Yanai, A.Takahashi, T.Taguchi
- Journal Title
  
  Chem.Commun.
  
  Volume: 46 Pages: 8728-8730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Carbon Acid Induced Mukaiyama Aldol Reaction of Sterically Hindered Ketones.2010
- Author(s)
  H.Yanai, Y.Yoshino, A.Takahashi, T.Taguchi
- Journal Title
  
  J.Org.Chem. 75
  
  Pages: 5375-5378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Highly Effective Vinylogous Mukaiyama-Michael Reaction Catalyzed by Silyl Methide Species Generated from 1,1,3,3-Tetrakis(trifluoro-methanesulfonyl)propane.2010
- Author(s)
  A.Takahashi, H.Yanai, M.Zhang, T.Sonoda, M.Mishima, T.Taguchi
- Journal Title
  
  J.Org.Chem. 75
  
  Pages: 1259-1265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] A Rapid and Convergent Synthesis of α, α-Difluoro-β-hydroxyketones through Regiospecific Defluorinative Alkylation Reaction2010
- Author(s)
  H.Yanai, T.Ichikawa, T.Taguchi
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 51 Pages: 2625-2628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Trihaloacetaldehyde N,O-acetals : useful building blocks for dihalomethylene compounds.2010
- Author(s)
  H.Yanai, T.Taguchi
- Journal Title
  
  Tetrahedron 66
  
  Pages: 4530-4541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Carbon Acid Induced Mukaiyama Aldol Reaction of Sterically Hindered Ketones2010
- Author(s)
  H.Yanai, Y.Yoshino, A.Takahashi, T.Taguchi
- Journal Title
  
  J.Org.Chem.
  
  Volume: 75 Pages: 5375-5378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] 1,4-Addition of Silicon Dienoates to α,β-Unsaturated Aldehydes Catalyzed by In situ-generated Silicon Lewis Acid.2010
- Author(s)
  H.Yanai, A.Takahashi, T.Taguchi
- Journal Title
  
  Chem.Commun. 46
  
  Pages: 8728-8730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Trihaloacetaldehyde N, O-Acetals : Useful Building Blocks for Dihalomethylene Compounds2010
- Author(s)
  H.Yanai, T Taguchi
- Journal Title
  
  Tetrahedron
  
  Volume: 66 Pages: 4530-4541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Novel defluorinative alkylation of trifluoroacetaldehyde N,O-acetal derivatives and its application to multi-component reaction.2009
- Author(s)
  H.Yanai, T.Taguchi
- Journal Title
  
  Chem.Commun.
  
  Pages: 1034-1036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Catalytic enantioselective synthesis of key intermediates for NET inhibitors using atropisomeric lactam chemistry2008
- Author(s)
  Kitagawa, O., Kurihara, D., Tanabe, H., Shibuya, T., Taguchi, T
- Journal Title
  
  Tetrahedron Lett 49
  
  Pages: 471-474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Catalytic enantioselective synthesis of key intermediates for NET inhibitors using atropisomeric lactam chemistry2008
- Author(s)
  北川理、田口武夫, ら
- Journal Title
  
  Tetrahedron Lett. 49
  
  Pages: 471-474
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2-(9H-xanthen- 9-y1)-ethyl]-1-fluorocyclopropane carboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist2008
- Author(s)
  Sakagami, K., Yasuhara, A., Chaki, S., Yoshikawa, R., Kawasaki, Y., Saito, A., Taguchi, T., Nakazato, A
- Journal Title
  
  Bioorg. Med. Chem 16
  
  Pages: 4359-4366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Synthesis, in vitro pharmacology, and pharmacokinetic profiles of 2-[1-amino-1-carboxy-2(9H-Xanthen-9-yl)-ethyl]-1-fluorocyclopropane-carboxylic acid and its 6-heptyl ester, a potent mGluR2 antagonist2008
- Author(s)
  坂上一成、田口武夫, ら
- Journal Title
  
  Bioorg.Med.Chem. 16
  
  Pages: 4359-4366
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Catalytic enantioselective synthesis of key intermediates for NET Inhibitors using atropisomeric lactam chemistry2008
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 63
  
  Pages: 471-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Tetrakis(trifluoromethanesulfonyl)propane : Highly effective Bronsted Acid Catalyst for Vinylogous Mukaiyama-Michael Reaction of α,β-Enones with Silyloxyfurans.2008
- Author(s)
  A.Takahashi, H.Yanai, T.Taguchi
- Journal Title
  
  Chem.Commun.
  
  Pages: 2385-2387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590013
[Journal Article] Scalable Synthesis of (+)-2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6- dicarboxylic Acid as a Potent and Selective Group II Metabotropic Glutamate Receptor Agonist2007
- Author(s)
  Sakagami, K., Kumagai, T., Taguchi, T., Nakazato, A
- Journal Title
  
  Chem. Pharm. Bull 55
  
  Pages: 37-43
- NAID
  110006151431
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Generation and reaction of heteroaromatic zirconocene: synthetic application to polycyclic heterocycles2007
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 2477-2480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Scalable Synthesis of(+)-2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxyhc Acid as a Potent and Selective Group II Metabotropic Gllutamate Receptor Agollist2007
- Author(s)
  坂上一成、田口武夫, ら
- Journal Title
  
  Chem.Pharm.Bull. 55
  
  Pages: 37-43
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] γ,γ-ジアルコキシアリルジルコニウム種を用いた炭素-炭素結合形成反応の開発2007
- Author(s)
  田口武夫
- Journal Title
  
  有機合成科学協会誌 68
  
  Pages: 54-64
- NAID
  10018461932
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Convenient Synthesis of Fluorinated Quinoline, 1,2-Dihydroquinoline and 1,2,3,4-Tetrahydroquinoline Derivatives2007
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron 50
  
  Pages: 2011-2020
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Dimethylaluminium methide complex TfCHAlMe2: An efficient catalyst for Diels-Alder reaction of α, β-unsaturated lactones with cyclopentadiene2007
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron 63
  
  Pages: 12149-12159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Convenient synthesis of fluorhlated quinohine,1,2-dihydroquinohne and 1,2,3,4-tetrahydroquinoline derivatives2007
- Author(s)
  矢内光、田口武夫, ら
- Journal Title
  
  Tetrahedron 63
  
  Pages: 2153-2160
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Development of effective Lewis acids for the catalytic Diels-Alder reaction of α,β-unsaturated lactones with cyclopentadiene2007
- Author(s)
  Yanai, H., Takahashi, A., Taguchi, T
- Journal Title
  
  Tetrahedron Lett 48
  
  Pages: 2993-2997
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Development of effective Lewis acids for the catalytic Diels-Alder reaction of α, β-unsaturated lactones with cyclopentadiene2007
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 2993-2997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Development of effective Lewis acids for the catalytic Diek-Alderreaction of α,β-unsaturated lactones with cyclopentadiene2007
- Author(s)
  矢内光、田口武夫, ら
- Journal Title
  
  Tetrahedron Lett. 48
  
  Pages: 2993-2997
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Dimethylaluminum methide complex Tf_2CHAlMe_2 : an effective catalyst for Diels-Alder reaction of α,β-unsaturated lactone derivatives with cyclopantadiene2007
- Author(s)
  Yanai, H., Takahashi, A., Taguchi, T
- Journal Title
  
  Tetrahedron 63
  
  Pages: 12149-12159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Dimethylaluminum nlethide complex-Tf_2CHAlMe_2:an effective catalyst for Diels-Alder reaction of α,β-unsaturated lactone derivatives with cyclopantadiene2007
- Author(s)
  矢内光、田口武夫, ら
- Journal Title
  
  Tetrahedron 63
  
  Pages: 12149-12159
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Convenient synthesis of fluorinated quinoline, 1,2-dihydroquinoline and 1,2,3,4-tetrahydroquinoline Derivatives2007
- Author(s)
  Yanai, H., Mimura, H., Kawada, K., Taguchi, T
- Journal Title
  
  Tetrahedron 63
  
  Pages: 2153-2160
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Scalable Synthesis of (+)-2-Amino-3-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid as a Potent and Selective Group II Metabotropic Glutamate Receptor Agonist2007
- Author(s)
  田口武夫
- Journal Title
  
  Chem. Pharm. Bull. 55
  
  Pages: 37-43
- NAID
  110006151431
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Highly Enantioselective Synthesis of Atropisomeric Anilide Derivatives through Catalytic Asymmetric N-Arylation : Conformational Analysis and Application to Asymmetric Enolate Chemistry2006
- Author(s)
  田口武夫
- Journal Title
  
  J. Am. Chem. Soc. 128
  
  Pages: 12923-12931
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Highly Enantioselective Synthesis of Atropisomeric Anilide Derivatives through Catalytic Asymmetric N-Arylation:Conformational Analysis and Application to Asymmetric Enolate Chemistry2006
- Author(s)
  北川理、田口武夫, ら
- Journal Title
  
  J.Am.Chem.Soc. 128
  
  Pages: 12923-12931
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular [3+2]cycloaddition Reaction of α,β-Enoate Derivatives Having Allylsilane Parts : 1,1'-Biphenyl-2,2'-di(triflyl)amide (BIPAM) + 2Me_2AlCl as a Novel Lewis Acid2006
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 4181-4185
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Rh(I)-catalyzed Mild Intramolecular [4+2] cycloaddition Reactions of Ester-tethered Diene-yne Compounds2006
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 891-895
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular [3+2] cycloaddition reaction of α,β-enoate derivatives having allylsilane parts : 1,1'-biphenyl-2,2'-di(triflypamide (BIPAM) + 2Me2A1C1 as a Novel Lewis acid2006
- Author(s)
  Saito, A., Sakamoto, W., Yanai, H., Taguchi, T
- Journal Title
  
  Tetrahedron Lett 47
  
  Pages: 4181-4185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Catalytic Asymmetric Desymmetrization of meso-Diamide Derivatives through Enantioselective N-Allylation with a Chiral π-Allyl Pd Catalyst : Improvement and Reversal of the Enantioslectivity2006
- Author(s)
  田口武夫
- Journal Title
  
  J.Org.Chem. 71
  
  Pages: 2011-2013
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular [3+2] cycloaddition reaction of α,β-enoate derivatives having allylsiane parts:1,1'-biphenyl-2,2'-di(triflyl)amide (BIPAM)+2Me_2AlCl as a Novel Lewis acid2006
- Author(s)
  斉藤亜紀夫、田口武夫, ら
- Journal Title
  
  Tetrahedron Lett. 47
  
  Pages: 4181-4185
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] An Efficient Synthetic Method for Z-Fluoroalkene Dipeptide Isosteres : Application to the Synthesis of the Dipeptide Isostere of Sta-Ala2006
- Author(s)
  田口武夫
- Journal Title
  
  J. Fluorine Chem. 127
  
  Pages: 627-636
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Highly Enantioselective Synthesis of Atropisomeric Anilide Derivatives through Catalytic Asymmetric N-Arylation : Conformational Analysis and Application to Asymmetric Enolate Chemistry2006
- Author(s)
  Kitagawa, O., Yoshikawa, M., Tanabe, H., Morita, T., Takahashi, M., Dobashi, Y., Taguchi, T
- Journal Title
  
  J. Am. Chem. Soc 128
  
  Pages: 12923-12931
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] An efficient synthetic method for Z-fluoroalkene dipeptide isosteres:Apphcation to the synthesis of the dipeptide isostere of Sta-Ala2006
- Author(s)
  中村裕子、田口武夫, ら
- Journal Title
  
  J.Fluorine Chem. 127
  
  Pages: 627-636
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Efficient Synthesis of Optically Active Atropisomeric Anilides through Catalytic Asymmetric N-Arylation Reaction2005
- Author(s)
  田口武夫
- Journal Title
  
  J.Am.Chem.Soc. 127
  
  Pages: 3676-3677
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder reaction of 1,7,9-decatrienoates catalyzed by indium(III) trifluoromethanesulfonate in aqueous media2005
- Author(s)
  Yanai, H., Saito, A., Taguchi, T
- Journal Title
  
  Tetrahedron 61
  
  Pages: 7087-7093
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium mediated fluoroalkenylation reactions of 1,1-dibromo-1-fluoro alkene derivatives2005
- Author(s)
  斉藤亜紀夫、田口武夫, ら
- Journal Title
  
  J.Fluorine Chem. 126
  
  Pages: 1166-1173
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder Reaction of 1,7,9-Decatrienoates Catalyzed by Indium(III) Trifluoromethanesulfonate in Aqueous Media2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron 61
  
  Pages: 7087-7093
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium Mediated Stereoselective Synthesis of (Z)-1-Fluoro-2-alkenyl Alkyl and Trialkylsilyl Ethers from Dibromofluoromethylcarbinyl Ethers2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 5257-5261
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder reaction α-fluoroacrylate derivatives promoted by novel bidentate aluminum Lewis acid2005
- Author(s)
  斉藤亜紀夫、田口武夫, ら
- Journal Title
  
  J.Fluorine Chem. 126
  
  Pages: 709-714
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder Reaction of α-Fluoroacrylate Derivatives Promoted by Novel Bidentate Aluminum Lewis Acid2005
- Author(s)
  田口武夫
- Journal Title
  
  J.Fluorine Chem. 126
  
  Pages: 709-714
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Stereoselective Synthesis of (Z)-Fluoroalkenes Directed to Peptide Isosteres : Copper Mediated Reaction of Trialkylaluminium with 4,4-Difluoro-5-hydroxyallylic Alcohol Derivatives2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron 61
  
  Pages: 5741-5753
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder reaction α-fluoroacrylate derivatives promoted by novel bidentate aluminum Lewis acid2005
- Author(s)
  Saito, A., Yanai, H., Sakamoto, W., Takahashi, K., Taguchi, T
- Journal Title
  
  J. Fluorine Chem 126
  
  Pages: 709-714
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium mediated stereoselective synthesis of(Z)-1-fluoro-2-alkyl and trialkylsilyl ethers from dibromofluoromethlcarbinyl ethers2005
- Author(s)
  中川無我、田口武夫, ら
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 5257-5261
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Indium(III) Triflate Catalyzed Tandem Azidation/1,3-Dipolar Cycloaddition Reaction of ω,ω-Dialkoxyalkyne Derivatives with Trimethylsilyl Azide2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8639-8643
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Copper-catalyzed Addition Reaction of γ,γ-dialkoxyallylic Zirconium Species with Imines2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron Lett. 46
  
  Pages: 8381-8383
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Intramolecular Diels-Alder reaction of 1,7,9-decatrienoates catalyzed by indium(III) trifluoromethanes ulfonate in aqueous media2005
- Author(s)
  矢内光、田口武夫, ら
- Journal Title
  
  Tetrahedron 61
  
  Pages: 7087-7093
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Lewis Acid Promoted Reactions of γ,γ-Dialkoxyallylic Zirconium Species with Various Carbonyl Compounds2005
- Author(s)
  田口武夫
- Journal Title
  
  Tetrahedron 61
  
  Pages: 10868-10879
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium mediated fluoroalkenylation reactions of 1,1-dibromo- 1-fluoroalkene derivatives2005
- Author(s)
  Saito, A., Nakagawa, M., Taguchi, T
- Journal Title
  
  J. Fluorine Chem 126
  
  Pages: 1166-1173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium mediated stereoselective synthesis of (Z)-1-fluoro-2-alkyl and trialkylsilyl ethers from dibromofluoromethlcarbinyl ethers2005
- Author(s)
  Nakagawa, M., Saito, A., Soga, A., Yamamoto, N., Taguchi, T
- Journal Title
  
  Tetrahedron Lett 46
  
  Pages: 5257-5261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Stereoselective synthesis of (Z)-fluoroalkenes directed to peptide isosteres : copper mediated reaction of trialkylaluminum with 4,4-difluoro-5-hydroxyallylic alcohol derivatives2005
- Author(s)
  Nakamura, Y., Okada, M., Sato, A., Horikawa, H., Koura, M., Saito, A., Taguchi, T
- Journal Title
  
  Tetrahedron 61
  
  Pages: 5741-5753
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Stereoselective synthesis of(Z)-fluoroalkenes directed to peptide isosteres:copper mediated reaction of triarkylaluminum with 4,4-difluoro-5-hydroxyallylic alcohol derivatives2005
- Author(s)
  中村裕子、田口武夫, ら
- Journal Title
  
  Tetrahedron 61
  
  Pages: 5741-5753
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Diastereoselective Intramolecular Ester Transfer Reaction of N-Alkenylcarbamate Derivatives Mediated by Zirconocene-butene Complex : Preparation of α,γ-Disubstituted γ-Aminobutyric Acid(GABA) Derivatives and 2,4-Disubstituted Pyrrolidine Derivatives2005
- Author(s)
  田口武夫
- Journal Title
  
  Synthesis
  
  Pages: 2046-2054
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Chromium-mediated Fluoroalkenylation Reactions of 1,1-Dibromo-1-fluoroalkane and 1-Bromo-1-Fluoroalkene Derivatives2005
- Author(s)
  田口武夫
- Journal Title
  
  J.Fluorine Chem. 126
  
  Pages: 1166-1173
- Data Source
  KAKENHI-PROJECT-17590015
[Journal Article] Zirconocene-Mediated and/or Catalyzed Unprecedented Coupling Reactions of Alkoxymethyl-Substituted Styrene Derivatives2005
- Author(s)
  田口武夫
- Journal Title
  
  J.Org.Chem. 70
  
  Pages: 4354-4359
- Data Source
  KAKENHI-PROJECT-17590015
[Patent] ビス(トリフルオロメタンスルホニル)エチル基を有する化合物及び酸触媒、並びにその製造方法2010
- Inventor(s)
  田口武夫、矢内光
- Industrial Property Rights Holder
  セントラル硝子株式会社、東京薬科大学
- Industrial Property Number
  2010-281174
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] ジフルオロホモアリルアルコールのC-F結合活性化を基軸とするフルオロオレフィン,クロロオレフィンの選択的合成2011
- Author(s)
  矢内光,岡田はる奈,佐藤梓,岡田みどり,田口武夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] アレーン骨格を利用した多価炭素酸の合成と酸触媒としての利用2011
- Author(s)
  小倉弘,藤田聖也,矢内光,田口武夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] 立体的に込み合ったケトンに対する効率的なMukaiyamaアルドール反応の開発2010
- Author(s)
  吉野泰裕,高橋新,矢内光,田口武夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] フッ素の特異性に着目した反応開発と機能創出2010
- Author(s)
  田口武夫
- Organizer
  日本化学会第4回関東支部大会
- Place of Presentation
  つくば
- Year and Date
  2010-08-31
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] シリルビス(トリフルオロメタンスルホニル)メチドを触媒とするα,β-不飽和アルデヒドへの1,4-付加反応2010
- Author(s)
  矢内光,高橋新,田口武夫
- Organizer
  第34回フッ素化学討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] ジフルオロホモアリルアルコール類に対する多彩な脱フッ素アリル置換反応2010
- Author(s)
  矢内光,岡田はる奈,佐藤梓,岡田みどり,田口武夫
- Organizer
  第34回フッ素化学討論会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] 3,3-ジフルオロ-1-アルケンを用いるフルオロアルケニルアジドの位置および立体選択的合成2010
- Author(s)
  佐藤謙介,矢内光,佐藤梓,中村裕子,岡田みどり,田口武夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] Tetrakis(trifluoromethanesulfonyl)propane : Highly effective Bronsted acid catalyst for C-C bond forming reactions of 2-silyloxyfurans with carbonyl compounds2010
- Author(s)
  A.Takahashi, H.Yanai, Y.Yoshino, T.Taguchi
- Organizer
  16th European Symposium on Fluorine Chemistry
- Place of Presentation
  ユブリアナスロベニア
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] ポリハロケトン類の有用な保護基:N-ベンジル-N,O-アセタール2009
- Author(s)
  矢内光,市川辰徳,田口武夫
- Organizer
  第33回フッ素化学討論会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] テトラキス(トリフルオロメタンスルホニル)プロパンを炭素酸触媒として用いた2-シリルオキシフランのα,β-不飽和アルデヒドに対する共役付加反応2009
- Author(s)
  高橋新,矢内光,加藤麻衣子,田口武夫
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] 炭素酸触媒を用いるジアステレオ選択的ビニロガスMukaiyama-Michael反応2009
- Author(s)
  高橋新,矢内光,田口武夫
- Organizer
  第33回フッ素化学討論会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] 脱フッ素アリル置換反応による官能基化されたフルオロアルケンの合成2008
- Author(s)
  佐藤謙介,矢内光,福田寛人,中村裕子,岡田みどり,田口武夫
- Organizer
  第32回フッ素化学討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] テトラキス(トリフルオロメタンスルホニル)プロパンをBronsted酸触媒とするビニロガスMukaiyama-aldol反応の開発2008
- Author(s)
  矢内光,吉野泰裕,高橋新,田口武夫
- Organizer
  第32回フッ素化学討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] 炭素酸触媒を用いるビニロガスMukaiyama-Michael反応の開発2008
- Author(s)
  高橋新,矢内光,田口武夫
- Organizer
  第32回フッ素化学討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590013
[Presentation] トリフルオロアセトアルデヒドN,O-アセタール:C-F結合切断に基づくジフルオロメチルアニオン前駆体としての利用2008
- Author(s)
  矢内光,三村英之,河田恒佐,田口武夫
- Organizer
  第32回フッ素化学討論会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590013

1. KATAGAWA Osamu (30214787)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
2. MORIKAWA Tsutomu (40166393)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HANZAWA Yuji (10096688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YANAI Hikaru (10408685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
5. ITO Hisanaka (70287457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 淵上寿雄 (10016701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 檜山爲次郎 (90026295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宇根山健治 (00033150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丸岡啓二 (20135304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 米田徳彦 (50001219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小林義郎 (90057282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 池川信夫 (50016119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAGUCHI Takeo 田口 武夫

田口 武夫 タグチ タケオ

Research Projects

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Preparation of functionalized organofluorine compounds toward drug discoveryPrincipal Investigator

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Development of synthetic methodogies for organofluorine compounds in medicinal chemistryPrincipal Investigator

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Development of new synthetic methods for organofluorine compounds of biomedical interestPrincipal Investigator

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フッ素原子による機能の創出Principal Investigator

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Development of asymmetric synthetic method for organofluorine compounds of biological interestsPrincipal Investigator

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Development of New Synthetic Methods for the Preparation of Organic Fluorine Compounds and the Application to Fluorinated Biological SubstancesPrincipal Investigator

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有機フッ素化合物の新合成法の開発と含フッ素生理活性物質合成への応用Principal Investigator

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含フッ素活性型ビタミンD⊇の合成研究

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[Book] フッ素化学入門2010基礎と応用の最前線2010

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[Book] Fluorine in Medicinal Chemistry and Chemical Biology2009

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[Book] Acid Catalysis in Modern Organic Synthesis2008

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[Book] フッ素系材料の応用技術2006

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[Journal Article] Copper mediated defluorinative allylic alkylation of difluorohomoallyl alcohol derivatives directed to an efficient synthetic method for (Z)-fluoroalkene dipeptide isosteres.2011

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[Journal Article] Copper-free defluorinative alkylation of allylic difluorides through Lewis acid-mediated C-F bond activation.2011

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TAGUCHI Takeo 田口武夫

田口武夫タグチタケオ