KAKEMI Masawo 掛見正郎

Researcher Number	00019134
Other IDs
Affiliation (based on the past Project Information) *help	2003 – 2008: 大阪薬科大学, 薬学部, 教授 1993 – 1994: 大阪薬科大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Medical pharmacy / Physical pharmacy
Keywords	Principal Investigator 日内変動 / 生体恒常系 / 時間薬理学 / PK-PD / トルブタミド / 糖尿病治療薬 / sulfonylureas / PK-PD Correlation / pharmacodynamics / pharmacokinetics … More / hypoglycemic effect / insulin / circadian rhythm / tolbutamide / PK-PD解析 / スルホニルウレア / グルコーストランスポーター / トランスポーター / GLUT4 / Optimisation of Dosage Regimen / Pharmacodynamics / Pharmacokinetics / Arginine-vasopressin / Salmon-calcitonin / Captopril / Plasma Calcium Regulation / Blood Pressure Regulation / モデル解析 / 日内変動モデル / フォーマコダイナミックス / フォーマコキネティクス / サケカルシトニン / 投与計画 / バイオアベイラビリティー / 抗利尿ホルモン / アルギニン・バソプレッシン / 最適投与計画 / ファーマコダイナミックス / ファーマコキネティクス / アルギニンバソプレッシン / サケ・カルシトニン / カプトプリル / カルシウム調節系 / 血圧調節系 / GKラット / ZDFラット / 糖尿病 / 糖尿病自然発症モデル / 概日リズム / NIDDM / 薬効解析学 Less

Optimization of Dosage Regimens Using a Mechanism-based PK-PD ModelPrincipal Investigator
- Principal Investigator
  
  KAKEMI Masawo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Optimization of dosage regimen using a mechanism-based pharmacokinetic-pharmacodynamic modelingPrincipal Investigator
- Principal Investigator
  
  KAKEMI Masawo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
Development of a new method for bioavailability assessment using a pharmacokineic/pharmacodynamic modelPrincipal Investigator
- Principal Investigator
  
  KAKEMI Masawo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2009 2008 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] 広義薬物動態学、第8章、時間薬理学と時間治療2009
- Author(s)
  掛見正郎(編)
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-18590159
[Book] 広義薬物動態学2009
- Author(s)
  掛見正郎
- Total Pages
  435
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-18590159
[Journal Article] エトポシドの消化管吸収における薬物相互作用の解析2006
- Author(s)
  西村知佐子, 南田望至, 宮崎誠, 岩永一範, 掛見正郎
- Journal Title
  
  TDM研究 23(4)
  
  Pages: 272-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590159
[Journal Article] Controlled release of plasmid DNA from hydrogels prepared from gelatin cationized by different amine compounds2006
- Author(s)
  T. Kushibiki, R. Tomoshige, K. Iwanaga, M. Kakemi, and Y. Tabata
- Journal Title
  
  J. Control. Release 112
  
  Pages: 249-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590159
[Journal Article] Disposition of Lipid-Based Formulation in the Intestinal Tract Affects the Absorption of Poorly Water-Soluble Drugs2006
- Author(s)
  Kazunori Iwanaga, Toshihiro Kushibiki, Makoto Miyazaki and Masawo Kakemi
- Journal Title
  
  Biol. Pharm. Bull. 29(3)
  
  Pages: 508-512
- NAID
  110005602132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590159
[Journal Article] In vitro transfection of plasmid DNA by cationized gelatin prepared from different amine compounds2006
- Author(s)
  T. Kushibiki, R. Tomoshige, K. Iwanaga, M. Kakemi, and Y. Tabata
- Journal Title
  
  J. Biomater. Sci. Polym. Ed. 17
  
  Pages: 645-658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590159
[Journal Article] Effect of Circadian Rhythm on Pharmacokinetics-Pharmacodynamics of Salmon Calcitonin in Rats2005
- Author(s)
  Makoto MIYAZAKI, Naoya HOSHINO, Nobuhiro TAKEDA, Kazunori IWANAGA, Masawo KAKEMI
- Journal Title
  
  The Journal of Therapeutic Drug Monitoring 22
  
  Pages: 40-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590144
[Journal Article] Effect of Circadian Rhythm on Pharmacokinetics-Pharmacodynamics of Tolbutamide in Rats2004
- Author(s)
  Makoto MIYAZAKI, Toshiki FUJII, Kumiko MIYAKE, Kazunori IWANAGA, Masawo KAKEMI
- Journal Title
  
  The Journal of Therapeutic Drug Monitoring 21
  
  Pages: 26-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590144
[Journal Article] Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (II) : Effect of Protease Inhibitor on the Pharmacokinetic-Pharmacodynamic Relationship after Intranasal Administration.2003
- Author(s)
  Makoto Miyazaki, Susumu Nakade, Kazunori Iwanaga, Kazuhiro Morimoto, Masawo Kakemi
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 18
  
  Pages: 358-364
- NAID
  10011952849
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590144
[Journal Article] Contribution of sympathetic nervous system activity during administration of carvedirol in rats with dilated cardiomyopathy2003
- Author(s)
  Kenichi Watanabe, Yuichi Abe, Shinji Sato, Mir Wahed, Juan Wen, Gurusamy Narashiman, Meilei Ma, Fadia Ali, Yuki Saito, Palaniyandi Suresh, Ken Sakurai, Mayako Soga, Yusuke Nagai, Toshihiro Takahashi, Go Hasegawa, Makoto Naito, Hitoshi Tachikawa, Naohito Tanabe, Makoto Komada, Yoshifusa Aizawa, Kenichi Yamaguchi, Makoto Miyazaki, Masawo Kakemi
- Journal Title
  
  J.Cardiovascular Pharmacology 42 (suppl.1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590144
[Journal Article] Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (I) : Pharmacokinetic-Pharmacodynamic Modeling Based on the Endogenous Ca Regulation System2003
- Author(s)
  Makoto Miyazaki, Susumu Nakade, Kazunori Iwanaga, Kazuhiro Morimoto, Masawo Kakemi
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 18
  
  Pages: 350-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590144
[Presentation] 糖尿病ラットにおけるトルブタミドの体内動態と血糖低下効果における日周変動2009
- Author(s)
  麝嶋美希, 宮崎誠, 岩永一範, 掛見正郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-18590159
[Presentation] ビタミンB12の体内動態における日周リズムと体温リズムへの影響2008
- Author(s)
  宮崎誠, 松岡恵美子, 岩永一範, 掛見正郎
- Organizer
  第15回日本時間生物学会学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-18590159
[Presentation] PK-PD Assessment of Antihypertensive Dugs in Spontaneously Hypertensive Rats - A Correlation between Hypotensive Effect and Beta-Blocking Activity -2008
- Author(s)
  後北桃子, 宮崎誠, 岩永一範, 掛見正郎
- Organizer
  第23回日本薬物動態学会年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-18590159
[Presentation] 高血圧治療薬セリプロロールによるインスリンの血糖低下効果への影響2008
- Author(s)
  山瀬大雄, 近藤弘美, 宮崎誠, 岩永一範, 掛見正郎
- Organizer
  第18回日本医療薬学会年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18590159
[Presentation] Interaction of prazosin and metoprolol in spontaneously hypertensive rats - pk-pd assessment based on blood pressure regulatory system -2006
- Author(s)
  成橋真也, 宮崎誠, 岩永一範, 掛見正郎
- Organizer
  第21回日本薬物動態学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590159
[Presentation] Is glucose transporter associated with circadian variation in hypoglycemic effect of tolbutamide?2006
- Author(s)
  宮崎誠, 武田伸弘, 藤井俊樹, 岩永一範, 掛見正郎
- Organizer
  第21回日本薬物動態学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590159

1. IWANAGA Kazunori (20257900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. MIYAZAKI Makoto (10319593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

KAKEMI Masawo 掛見 正郎

Research Projects

Research Products

Co-Researchers

Optimization of Dosage Regimens Using a Mechanism-based PK-PD ModelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Optimization of dosage regimen using a mechanism-based pharmacokinetic-pharmacodynamic modelingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new method for bioavailability assessment using a pharmacokineic/pharmacodynamic modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 広義薬物動態学、第8章、時間薬理学と時間治療2009

Author(s)

Publisher

Data Source

[Book] 広義薬物動態学2009

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] エトポシドの消化管吸収における薬物相互作用の解析2006

Author(s)

Journal Title

Data Source

[Journal Article] Controlled release of plasmid DNA from hydrogels prepared from gelatin cationized by different amine compounds2006

Author(s)

Journal Title

Data Source

[Journal Article] Disposition of Lipid-Based Formulation in the Intestinal Tract Affects the Absorption of Poorly Water-Soluble Drugs2006

Author(s)

Journal Title

NAID

Data Source

[Journal Article] In vitro transfection of plasmid DNA by cationized gelatin prepared from different amine compounds2006

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Circadian Rhythm on Pharmacokinetics-Pharmacodynamics of Salmon Calcitonin in Rats2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of Circadian Rhythm on Pharmacokinetics-Pharmacodynamics of Tolbutamide in Rats2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (II) : Effect of Protease Inhibitor on the Pharmacokinetic-Pharmacodynamic Relationship after Intranasal Administration.2003

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Contribution of sympathetic nervous system activity during administration of carvedirol in rats with dilated cardiomyopathy2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Estimation of Bioavailability of Salmon Calcitonin from the Hypocalcemic Effect in Rats (I) : Pharmacokinetic-Pharmacodynamic Modeling Based on the Endogenous Ca Regulation System2003

Author(s)

Journal Title

Description

Data Source

[Presentation] 糖尿病ラットにおけるトルブタミドの体内動態と血糖低下効果における日周変動2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KAKEMI Masawo 掛見正郎