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YUBISUI Toshitsugu
指吸 俊次
Connect your ORCID iD
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Alternative Names
指吸 俊次
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Researcher Number
00019564
Other IDs
Affiliation (based on the past Project Information)
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1997 – 1998: 高知大学, 理学部, 教授
1994 – 1995: 高知大学, 理学部, 教授
1986 – 1993: 大分医科大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General medical chemistry
/
Functional biochemistry
Except Principal Investigator
General medical chemistry
/
物質生物化学
/
Respiratory organ internal medicine
/
Developmental biology
/
Pathological medical chemistry
Keywords
Principal Investigator
変異酵素 / 遺伝性メトヘモグロビン血症 / NADH-シトクロムb_5還元酵素 / シトクロムb_5 / cDNAクローニング / 硝酸還元酵素 / NADHーシトクロムb_5還元酵素 / 赤血球型 / 全身型 / 血液細胞型
…
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/ 遺伝性メトヘモクロビン血症 / 脳における機能 / 脳での局在部位 / cDNAクロ-ニング / CYTOCHROME b_5 / cDNA CLONING / FUNCTIONS IN BRAIN / LOCALIZATION IN BRAIN / ヌクレオチド結合モチーフ / シトクロムb5還元酵素 / 結晶構造 / アミノ酸置換 / シトクロムP450還元酵素 / ヌクレオチド / モチーフ / NADH-シトクロムb5還元酵素 / ミノ酸置換 / Nucleotide-binding motif / Cytochrome b5 reductase / Nitrate reductase / Crystal structure / Mutagenesis / Cytochrome P450 reductase / シトクロムb5遺伝子 / リコンビナントb5 / シトクロムP450 / 薬物代謝 / ホルモン代謝 / 遺伝子 / 発現調節 / 機能解析 / タンパク質発現 / Cytochrome b5 / cDNA cloning / gene expression / tunicate / co-expression / recombinant protein / シトクロムb_5還元酵素 / 遺伝子構造 / 遺伝性疾患 / 点突然変異 / Ser→Pro突然変異 / 遺伝子構造解析 / シトクロムb_5還元酵素欠損 / 大腸菌内発現 / cDNA / エクソン / cDNA発現 / 部位特異的突然変異 / NADH-cytochrome b_5 reductase / Gene structure / Hereditary deficiency / Point mutation / Ser-127->Pro mutant / Mutant enzyme
…
More
Except Principal Investigator
極長鎖脂肪酸 / 脂肪酸伸長反応 / 脂肪酸伸長 / 脂肪酸縮合 / ANAE-1 / 遺伝性メトヘモグロビン血症 / NADH-チトクロム【b_5】還元酵素 / 全翻訳配列 / アミノ酸配列 / 赤血球型と知能障害型 / リグノセリン酸水酸化反応 / 脂肪酸伸長酵素 / ミエリン形成 / 脂肪酸縮合酵素 / モノエン脂肪酸 / シトクロムb_5還元酵素 / 部位特異的変異 / 2-ケトアシルCoA還元酵素 / 高血圧 / NADHーシトクロムb_5還元酵素 / 2ーケトアシルCoA還元酵素 / 動脈硬化 / モノ不飽和脂肪酸 / CHAPSO / thiolesterase / 副腎白質ジストロフィ- / 白血球 / セレブロシド / 粗面小胞体 / 滑面小胞体 / 脂肪酸水酸化 / ブタ動脈壁細胞 / 牛血清アルブミン / fatty acid elongation / myelination / fatty acid condensation / monoenoic fatty acid / cytochrome b_5 reductase / site directed mutagenesis / 2-ketoacyl-CoA reductase / hypertension / 長鎖脂肪酸 / 細胞骨格 / オリゴデンドログリア / ミクロソ-ム / 脂肪酸伸長活性 / 縮合活性 / カルシュウム / アシルCoA合成酵素 / コルヒチン / サイクリックAMP / 脳ミクロソ-ム / パ-コ-ル法 / 細胞培養 / Long-Chain-Fatty Acid / Cytoskeleton / Oligodendroglia / Microsomes / Fatty Acid Elongation / Condensation / Calcium / Acyl-CoA Synthetase / ANAE-I / マクロファージ遊走阻止 / 類上皮細胞肉芽腫 / マクロフアージ遊走阻止活性 / MIF / epitherioid cell granuloma / ホヤ / 無性生殖 / 多能性細胞 / アミノペプチダーゼ / セリンプロテアーゼ / レチノイン酸 / 細胞増殖 / 脱分化 / 出芽 / kringle / モザイクタンパク質 / リコンビナントタンパク質 / 細胞増殖因子 / 分化誘導 / アミノペプチターゼ / trefoilモチーフ / tunicate / asexual reproduction / multipotency / aminopeptidase / serine protease / retinoic acid / cell proliferation / dedifferentiation / 長鎖脂肪酸伸長反応 / 極長鎖脂肪酸伸長反応 / モノクローナル抗体 / アラキジン酸-CoA / アラキドン酸-CoA / NADH-シトクロムb_5還元酵素 / ラジオ液体クロマトグラフィー / 副腎白質ジストロフィー症 / チトクロム【b_5】 / 体外免疫法 / ミクロソーム / 極長鎖脂肪酸伸長 / 脂肪膜の相分離 / SH基修飾剤 / Fatty acid elogation / Very-long-chain fatty acid elongation / Monoclonal antibody Arachidyl-CoA / Arachidonoyl-CoA / NADH-cytochrome b_5 reductase / Redio-liquid chromatography
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Research Projects
(
13
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Regulation of gene expression and function of cytochrome b5
Principal Investigator
Principal Investigator
YUBISUI Toshitsugu
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for international Scientific Research
Research Field
Functional biochemistry
Research Institution
Kochi University
Structure and function of dedifferentiation factors with proteolytic and mitogenic activities in budding tunicates
Principal Investigator
KAWAMURA Kazuo
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Developmental biology
Research Institution
Kochi University
Structure of the New Motifs for Nucleotide-binding
Principal Investigator
Principal Investigator
YUBISUI Toshitsugu
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for international Scientific Research
Research Institution
Kochi University
遺伝性メトヘモグロビン血症の発症機構の解明
Principal Investigator
Principal Investigator
指吸 俊次
Project Period (FY)
1993
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
大分医科大学
Biological activity of the ANAE-1 derived from the granuloma macrophage
Principal Investigator
TSUDA Tomiyasu
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Respiratory organ internal medicine
Research Institution
Oita Medical University
遺伝性メトヘモグロビン血症の発症機構の解明
Principal Investigator
Principal Investigator
指吸 俊次
Project Period (FY)
1992
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
大分医科大学
遺伝性メトヘモグロビン血症の発症機構の解明
Principal Investigator
Principal Investigator
指吸 俊次
Project Period (FY)
1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
大分医科大学
IDENTIFICATION OF NEW SPECIES OF BRAIN-SPECIFIC CYTOCHROME b_5
Principal Investigator
Principal Investigator
YUBISUI Toshitsugu
Project Period (FY)
1991 – 1992
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
OITA MEDICAL UNIVERSITY
Metabolic Regulation in Fatty Acid Elongation System
Principal Investigator
TAKESHITA Masazumi
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
General medical chemistry
Research Institution
OITA MEDICAL UNIVERSITY
Interaction between brain microsomal long-chain fatty acid synthesis systems and cytoskeletons.
Principal Investigator
SAKAI KUMIKO
,
吉田 敏
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Oita Medical University
Gene structure of NADH-cytochrome b_5 reductase and regulation of expression
Principal Investigator
Principal Investigator
YUBISUI Toshitsugu
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
General medical chemistry
Research Institution
Medical College of Oita
遺伝性メトヘモグロビン血症の赤血球型と知能障害型の病態に関する研究
Principal Investigator
竹下 正純
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
大分医科大学
Analysis of Brain Fatty Acid Metabolism and its Abnormality by Application of Monoclonal Antibody
Principal Investigator
TAKESHITA Masazumi
Project Period (FY)
1985 – 1987
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Pathological medical chemistry
Research Institution
Nedical College of Oita
# of Projects (Dsc)
# of Projects (Asc)
1.
TAKESHITA Masazumi
(50019551)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
2.
SHIRABE Komei
(50179058)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
YOSHIDA Satoshi
(50158440)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
4.
TAMURA Minoru
(00128349)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
5.
キャンベル ウイルバーH
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
SAKAI KUMIKO
(60225753)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
TSUDA Tomiyasu
(80040567)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
MIYAZAKI Eishi
(00264333)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
KAWAMURA Kazuo
(30136361)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
ポーター トッド D.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
キャンベル ウイルバー
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
CAMPBELL Wilbur h
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
PORTER Todd d
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
ポーター トッドD.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
ステッグルス アランW.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
PORTER Todd D.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
CAMPBELL Wilbur H.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
STEGGLES Alen W.
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
キャンベル ウイルパーH
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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