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YUBISUI Toshitsugu  指吸 俊次

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指吸 俊次

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Researcher Number 00019564
Other IDs
Affiliation (based on the past Project Information) *help 1997 – 1998: 高知大学, 理学部, 教授
1994 – 1995: 高知大学, 理学部, 教授
1986 – 1993: 大分医科大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
General medical chemistry / Functional biochemistry
Except Principal Investigator
General medical chemistry / 物質生物化学 / Respiratory organ internal medicine / Developmental biology / Pathological medical chemistry
Keywords
Principal Investigator
変異酵素 / 遺伝性メトヘモグロビン血症 / NADH-シトクロムb_5還元酵素 / シトクロムb_5 / cDNAクローニング / 硝酸還元酵素 / NADHーシトクロムb_5還元酵素 / 赤血球型 / 全身型 / 血液細胞型 … More / 遺伝性メトヘモクロビン血症 / 脳における機能 / 脳での局在部位 / cDNAクロ-ニング / CYTOCHROME b_5 / cDNA CLONING / FUNCTIONS IN BRAIN / LOCALIZATION IN BRAIN / ヌクレオチド結合モチーフ / シトクロムb5還元酵素 / 結晶構造 / アミノ酸置換 / シトクロムP450還元酵素 / ヌクレオチド / モチーフ / NADH-シトクロムb5還元酵素 / ミノ酸置換 / Nucleotide-binding motif / Cytochrome b5 reductase / Nitrate reductase / Crystal structure / Mutagenesis / Cytochrome P450 reductase / シトクロムb5遺伝子 / リコンビナントb5 / シトクロムP450 / 薬物代謝 / ホルモン代謝 / 遺伝子 / 発現調節 / 機能解析 / タンパク質発現 / Cytochrome b5 / cDNA cloning / gene expression / tunicate / co-expression / recombinant protein / シトクロムb_5還元酵素 / 遺伝子構造 / 遺伝性疾患 / 点突然変異 / Ser→Pro突然変異 / 遺伝子構造解析 / シトクロムb_5還元酵素欠損 / 大腸菌内発現 / cDNA / エクソン / cDNA発現 / 部位特異的突然変異 / NADH-cytochrome b_5 reductase / Gene structure / Hereditary deficiency / Point mutation / Ser-127->Pro mutant / Mutant enzyme … More
Except Principal Investigator
極長鎖脂肪酸 / 脂肪酸伸長反応 / 脂肪酸伸長 / 脂肪酸縮合 / ANAE-1 / 遺伝性メトヘモグロビン血症 / NADH-チトクロム【b_5】還元酵素 / 全翻訳配列 / アミノ酸配列 / 赤血球型と知能障害型 / リグノセリン酸水酸化反応 / 脂肪酸伸長酵素 / ミエリン形成 / 脂肪酸縮合酵素 / モノエン脂肪酸 / シトクロムb_5還元酵素 / 部位特異的変異 / 2-ケトアシルCoA還元酵素 / 高血圧 / NADHーシトクロムb_5還元酵素 / 2ーケトアシルCoA還元酵素 / 動脈硬化 / モノ不飽和脂肪酸 / CHAPSO / thiolesterase / 副腎白質ジストロフィ- / 白血球 / セレブロシド / 粗面小胞体 / 滑面小胞体 / 脂肪酸水酸化 / ブタ動脈壁細胞 / 牛血清アルブミン / fatty acid elongation / myelination / fatty acid condensation / monoenoic fatty acid / cytochrome b_5 reductase / site directed mutagenesis / 2-ketoacyl-CoA reductase / hypertension / 長鎖脂肪酸 / 細胞骨格 / オリゴデンドログリア / ミクロソ-ム / 脂肪酸伸長活性 / 縮合活性 / カルシュウム / アシルCoA合成酵素 / コルヒチン / サイクリックAMP / 脳ミクロソ-ム / パ-コ-ル法 / 細胞培養 / Long-Chain-Fatty Acid / Cytoskeleton / Oligodendroglia / Microsomes / Fatty Acid Elongation / Condensation / Calcium / Acyl-CoA Synthetase / ANAE-I / マクロファージ遊走阻止 / 類上皮細胞肉芽腫 / マクロフアージ遊走阻止活性 / MIF / epitherioid cell granuloma / ホヤ / 無性生殖 / 多能性細胞 / アミノペプチダーゼ / セリンプロテアーゼ / レチノイン酸 / 細胞増殖 / 脱分化 / 出芽 / kringle / モザイクタンパク質 / リコンビナントタンパク質 / 細胞増殖因子 / 分化誘導 / アミノペプチターゼ / trefoilモチーフ / tunicate / asexual reproduction / multipotency / aminopeptidase / serine protease / retinoic acid / cell proliferation / dedifferentiation / 長鎖脂肪酸伸長反応 / 極長鎖脂肪酸伸長反応 / モノクローナル抗体 / アラキジン酸-CoA / アラキドン酸-CoA / NADH-シトクロムb_5還元酵素 / ラジオ液体クロマトグラフィー / 副腎白質ジストロフィー症 / チトクロム【b_5】 / 体外免疫法 / ミクロソーム / 極長鎖脂肪酸伸長 / 脂肪膜の相分離 / SH基修飾剤 / Fatty acid elogation / Very-long-chain fatty acid elongation / Monoclonal antibody Arachidyl-CoA / Arachidonoyl-CoA / NADH-cytochrome b_5 reductase / Redio-liquid chromatography Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (19 People)
  •  Regulation of gene expression and function of cytochrome b5Principal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Kochi University
  •  Structure and function of dedifferentiation factors with proteolytic and mitogenic activities in budding tunicates

    • Principal Investigator
      KAWAMURA Kazuo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Kochi University
  •  Structure of the New Motifs for Nucleotide-bindingPrincipal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kochi University
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  Biological activity of the ANAE-1 derived from the granuloma macrophage

    • Principal Investigator
      TSUDA Tomiyasu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Oita Medical University
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  遺伝性メトヘモグロビン血症の発症機構の解明Principal Investigator

    • Principal Investigator
      指吸 俊次
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      大分医科大学
  •  IDENTIFICATION OF NEW SPECIES OF BRAIN-SPECIFIC CYTOCHROME b_5Principal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Metabolic Regulation in Fatty Acid Elongation System

    • Principal Investigator
      TAKESHITA Masazumi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  Interaction between brain microsomal long-chain fatty acid synthesis systems and cytoskeletons.

    • Principal Investigator
      SAKAI KUMIKO, 吉田 敏
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Oita Medical University
  •  Gene structure of NADH-cytochrome b_5 reductase and regulation of expressionPrincipal Investigator

    • Principal Investigator
      YUBISUI Toshitsugu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Medical College of Oita
  •  遺伝性メトヘモグロビン血症の赤血球型と知能障害型の病態に関する研究

    • Principal Investigator
      竹下 正純
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      大分医科大学
  •  Analysis of Brain Fatty Acid Metabolism and its Abnormality by Application of Monoclonal Antibody

    • Principal Investigator
      TAKESHITA Masazumi
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nedical College of Oita
  • 1.  TAKESHITA Masazumi (50019551)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  SHIRABE Komei (50179058)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIDA Satoshi (50158440)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  TAMURA Minoru (00128349)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  キャンベル ウイルバーH
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SAKAI KUMIKO (60225753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TSUDA Tomiyasu (80040567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MIYAZAKI Eishi (00264333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAWAMURA Kazuo (30136361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ポーター トッド D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  キャンベル ウイルバー
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  CAMPBELL Wilbur h
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  PORTER Todd d
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ポーター トッドD.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ステッグルス アランW.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  PORTER Todd D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  CAMPBELL Wilbur H.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  STEGGLES Alen W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  キャンベル ウイルパーH
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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