AKABOSHI Mitsuhiko 赤星光彦

Researcher Number	00027418
Affiliation *help	1996 – 1999 : 京都大学, 原子炉実験所, 教授 1996 : 京都大学, 原子炉実験所 1992 – 1995 : 京都大学, 原子炉実験所, 助教授 1988 – 1990 : 京都大学, 原子炉実験所, 助教授
Review Section/Research Field	Principal Investigator Radiation science / 広領域 Except Principal Investigator Radiation science / Physical pharmacy / 放射線科学
Keywords	Principal Investigator シスプラチン / ^<195m>Pt / 希土類元素 / 254-S / TDDP / ヒラ細胞 / 標的量 / HPLC / CDDP / CBDCA … More Except Principal Investigator Tirapazamine / 生体還元物質 / 低温度温熱処置 / ニコチンアミド / BNCT / 中性子核反応 / Gd-NCT / Nicotinamide / 休止期細胞 / 急性低酸素細胞分画 / BPA / 中性子捕捉療法 / 99m-Tc Labeled Antitumor Antibody / combination treatment / 原子炉医療 / SCC7腫瘍細胞 / 99m-Tc標識抗腫瘍抗体 / Potentially lethal damage / 癌化学療法 / ボロンー10 / quiescent cell / 中性子捕促化合物 / ^<195m>Pt-標識カルボプラチン / 99mーTc標識抗腫瘍抗体 / ^<195m>Pt-標識シスプラチン / コロニー形成能 / 休止(静止)期細胞 / SCCVII腫瘍 / BpA / SCCVII / ^<195m>Pt標識シスプラチン / GdDTPA / 多核錯体 / 195mPt-標識シスプラチン / 中性子 / nicotinamide / 186-Re標識抗腫瘍抗体 / 再分布現象 / 多核錯断 / 細胞致死作用 / Reoxygenation / Quiescent cell / ホウ素核酸前駆物質 / Acutely hypoxic fraction / がん細胞 / Nuclear Medicine Tumor Therapy / Recruitment / 原子炉 / 99m-Tcジメルカプトコハク酸錯体 / Bioreductive agent / ^<195m>Pt-254-S / 195^mPt-標識シスプラチン / 中性子捕促療法 / Cisplatin / 潜在的致死的障害 / Nuclear Medicine Tumor Diagnosis / Radiolabeled cisplatin / ^<195m>Pt-carboplatin / ^<195m>Pt-標識-254-S / アポトーシス / 熱中性子 / 中性子捕捉反応 / 体内分布 / 99m-Tc-Dimercaptosuccinic Acid Complex / シスプラチン / ^<10>B熱中性子捕捉反応 / Nlcotinamide / Biodistribution / 腫瘍血管作動物質 / 99mーTcジメルカプトコハク酸錯体 / 核医学治療 / chemotherapy / DNA / カドミ比 / chronically hypoxic fraction / Neutron capture reaction / LQーモデル / 静止細胞 / Tlrapazamine / vasoactive agent / 急性低酸素分画 / ^<10>B / がんの核医学治療 / 慢性低酸素細胞分画 / 分裂死 / 休止期腫瘍細胞 / ^<195m>Pt-標識-シスプラチン / GdNCT / micronucleus assay / 相対的生物学的効果比 / 核医学診断 / Mild temparature hyperthermia / がんの核医学診断 / 慢性低酸素分画 / Polynuclear Metal Complex / 再酸素化現象 / Gd-DTPA / Mild hyperthermia / hypoxic call / 186ーRe標識抗腫瘍抗体 / Quiescent cells / RBE / 併用療法 / 放射化学 / 186-Re Labeled Antitumor Antibody / がん放射線治療 Less

Research Projects
(14results)
Co-Researchers
(19People)

An attempt to develop effective fractionated irradiation and chemotherpy by modifying intratumor microenvironment, referring to the effect on quiescent tumor cells.
- Principal Investigator
  
  MASUNAGA Shin-ichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
腫瘍内休止期細胞への効果を加味した中性子捕促化合物の効果投与様式の探究
- Principal Investigator
  
  MASUNAGA Shinichiro
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
An attempt to enhance the sensitivity of intratumor quiescent cells to radiation and/or chemotherapeutic agent using the characteristics of tumor vessels
- Principal Investigator
  
  MASUNAGA Shin-ichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Trial manufacture of the automatic and remote-controlled apparatus for the mass production of ^<195>mpt radiolabeled compoundsPrincipal Investigator
- Principal Investigator
  
  AKABOSHI Mitsuhiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  KYOTO UNIVERSITY
Study on the mechanism of antitumor adion of platinumcompounds by the utilization of 19.5mpf as the tracerPrincipal Investigator
- Principal Investigator
  
  AKABOSHI Mitsuhina
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
希土類元素とその化合物の細胞内分布と蓄積および生物学的作用に関する総合的研究Principal Investigator
- Principal Investigator
  
  赤星光彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
希土類元素とその化合物の細胞内分布と蓄積および生物学的作用に関する総合的研究Principal Investigator
- Principal Investigator
  
  赤星光彦
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Enhancement of chemosensitivity of the quiescent call populations in murine solid tumor by combination treatment with antitumor drugs and vasoactive agent
- Principal Investigator
  
  KAWAI Kenichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
Basic research for Gd-NCT
- Principal Investigator
  
  ONO Koji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  放射線科学
- Research Institution
  KYOTO UNIVERSITY
Study on the mechanism of synergistic effect of heat and anticanc agentPrincipal Investigator
- Principal Investigator
  
  AKABOSHI Mitsuhiko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  KYOTO UNIVERSITY
^<10>Bー熱中性子捕捉反応によるがん細胞DNA障害、細胞致死作用の放射化学的研究
- Principal Investigator
  
  上野陽里
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
原子炉中性子核反応によるがん細胞DNA障害、細胞致死作用機構の放射化学的研究
- Principal Investigator
  
  上野陽里
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Tumor Diagnosis and Therapy in Nuclear Medicine Using Radioactive Technetium and Rhenium Labeled Antitumor Antibody.
- Principal Investigator
  
  YOKOYAMA Akira
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
原子炉中性子核反応によるがん細胞DNA障害、細胞致死作用機構の放射化学的研究
- Principal Investigator
  
  上野陽里
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University

1. ONO Koji (90122407)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
2. MASUNAGA Shinichiro (80238914)

# of Collaborated Projects : 8results

# of Collaborated Products : 0results
3. KAWAI Kenichi (30110761)

# of Collaborated Projects : 6results

# of Collaborated Products : 0results
4. 上野陽里 (60025541)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. 小林慎江 (80027408)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. 北岡祥伯 (00027426)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
7. TAKADA Jitsuya (10115868)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
8. TANAKA Yoshiko (70027449)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
9. 芥田啓三 (70144285)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
10. 高橋正治 (00026931)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
11. 川本圭造 (70089134)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. 櫻井良憲 (20273534)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. YOKOYAMA Akira (90025685)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. FUJIBAYASHI Yasuhisa (50165411)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. ENDO Keigo (10115800)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. ARANO Yasushi (90151167)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. HORIUCHI KAZUKO (50144382)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. KINASHI Yuko (80252534)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 田野恵三 (00183468)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

AKABOSHI Mitsuhiko 赤星 光彦

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Trial manufacture of the automatic and remote-controlled apparatus for the mass production of ^<195>mpt radiolabeled compoundsPrincipal Investigator

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Study on the mechanism of antitumor adion of platinumcompounds by the utilization of 19.5mpf as the tracerPrincipal Investigator

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希土類元素とその化合物の細胞内分布と蓄積および生物学的作用に関する総合的研究Principal Investigator

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Study on the mechanism of synergistic effect of heat and anticanc agentPrincipal Investigator

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AKABOSHI Mitsuhiko 赤星光彦