SHIMIZU Akira 清水章

Researcher Number	00028581
Other IDs
Affiliation (based on the past Project Information) *help	2006: Osaka Medical College, Faculty of Medicine, Emeritus Professor, 医学部, 名誉教授 1992 – 2005: Osaka Medical College, Clinical Pathol., Prof., 医学部, 教授 1998: 大阪医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine Except Principal Investigator Laboratory medicine / Laboratory medicine / Circulatory organs internal medicine
Keywords	Principal Investigator 質量分析 / HCV / クリオグロブリン / トランスサイレチン / C型肝炎 / 補体寒冷活性化 / リウマチ因子 / コールドアクチベーション / 補体 / rheumatoid factor … More Except Principal Investigator DAF / PNH / 神経変性疾患 / トランスサイレチン / 質量分析 / 翻訳後修飾 / MACIF(CD59) / GPIアンカー / C9 / DTT / CD59 / mRNA / Transfection / PEDF / Autoantibody / Cancer / Proteomics / Adenocarcinoma / Biomarker / Diagnosis / 自己抗体 / エレクトロスプレーイオン化質量分析法 / ナノスプレー手法 / 異常Hb症 / アダクト分子 / 固定化酵素 / エレクトロスプレーイオン化質量分析 / 免疫沈降物 / 銅 / 亜鉛-SOD / 変異型 / 正常型比 / 新規変異種 / 超高感度分析 / 自家製ミクロキャピラリーカラム / ナノLC / アミノ酸配列 / 完全分子 / 家族性アミロイドポリニューロパチー / 老年性全身性アミロイドーシス / 亜硫酸塩 / アミロイドポリニューロパチー / 免疫沈降法 / アミロイド原性 / 亜硫酸化 / モリブデン補因子欠損症候群 / 修飾構造 / アミロイドーシス / 家族性 / 老年性 / 補体 / 補体制御蛋白 / C5bー8 / モノクロ-ナル抗体 / 合成ペプチド / ジスルフィド結合 / Complement / Monoclonal antibodies / GPI-anchor / 補体制御因子 / GPI-アンカー型蛋白質 / 癌化 / ヒト白血病培養細胞株 / シグナル伝達 / チロシンキナーゼ / 架橋 / カベオリン / PIアンカー / transfection / Complement ragulatory-proteins / PI-anchored proteins / Marignancy / Human leukemia cell lines / ナノESIMS法 / アポ型 / ホロ型比 / 細胞内酸化的ストレス / 銅結合金属蛋白 / 活性酸素種 / 銅イオン毒性 / ホロ型 / 遊離銅イオン毒性 / NanoESIMS method / Ration of Apo / Holo / Oxidative stress in the body / Cooper-binding protein / Active oxide species / Free cooper ion / Neurodegenerative disease / 拡張型心筋症 / 心筋炎 / エンテロウイルス / コクサッキーウイルス / C型肝炎ウイルス / アデノウイルス / ウイルス複製 / 左心室部分切除術 / dilated cardiomyopathy / myocarditis / enterovirus / coxsackievirus / hepatitis C virus / adenovirus / viral replication / partial left ventriculectomy / 発現プロテオミクス / 糖尿病性網膜症 / 血管新生制御因子 / 硝子体 / イオントラップ型質量分析計 / ソフトイオン化質量分析 / Expression Proteomics / Diabetic Retinopathy / Angiogenesis-modulated factor / Vitreous humor / Ion-trap MS / 癌プロテオミクス / 肺アデノカルシノーマ / 肺癌バイオマーカー / 2D-PAGE / α-エノラーゼ / ペルオキシレドキシン-6 / ベーチェット病 / プロテオーム / 電気泳動 / 免疫沈降 / 免疫プロッティング / 二次元電気泳動 / Behcet病 / Behecet's disease / autoantibody / proteome / mass spectrometry / electrophoresis / immunoprecipitation / immunoblotting Less

Identifications of diagnostic biomarkers specific binding to soluble proteins of adenocarcinoma A 549 cell lines by an autoantibodiomics
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Proteomics-based approach identifying autoantibodies in Behcet's disease
- Principal Investigator
  
  TAKEUCHI Toru
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Analysis of modified structures of transthyretin, elucidation of disease etiology of amyloidosis and application to clinical laboratory testsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Elucidation of the fine structure and the generation process of modified proteins (sulfonate, nitroso, et al.) application to clinical laboratory testPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Expression proteomics of angiogenesis-modulated factors in human vitreous humors derived from diabetic retinopathy
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
トランスサイレチン関連アミロイドーシスにおける繊維化分子機構の解明
- Principal Investigator
  
  岸川匡彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Evaluation of viral infection and trace elements in the myocardium of patients with idioipathic dilated cardiomyopathy
- Principal Investigator
  
  FUJIOKA Shigekazu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka Medical College
B cell clone proliferated in HCV infection and V regeon structure of RF correlated to complement clod activationPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
The quantification of ratios between apo to holo types of metal binding protein : a new indicator of the oxidative stress in cells
- Principal Investigator
  
  NAKANISHI Toyofumi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
神経疾患の原因となる変異蛋白質の質量分析による検出と構造決定および新診断法の確立
- Principal Investigator
  
  KISHIKAWA Masahiko
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Establishment and practical use of reference method for glyco-haemoglobin by mass spectrometryPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
金被覆ミクロキャピラリーLC装着質量分析による癌特異ペプチドの超高感度構造決定
- Principal Investigator
  
  NAKANISHI Toyohumi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Elucidation of complement cold activation and cryoglobulin formation associated with HCV infection.Principal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Study of the mechanism of in-vitro activation of complement and formation of cryoglobulin in the sera from patients with C type hepatitisPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akira
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Mechanisms involved in loss of PI-anchored proteins (DAF and CD59) in human leukemia cell lines.
- Principal Investigator
  
  HATANAKA Michiyo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College
Studies on the mechanisms of C9 activation and of C9 inactivation by the regulatory protein(MACIF)
- Principal Investigator
  
  HATANAKA Michiyo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Osaka Medical College

All 2006 2005 2004 Other

All Journal Article

[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci 838(1)
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N.
- Journal Title
  
  Clin.Cancer Res. 12(21)
  
  Pages: 6415-6420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci 838・1
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis.2006
- Author(s)
  Nakanishi T, Takeuchi T, Ueda K, Murao H, Shimizu A.
- Journal Title
  
  J Chromatogr B 838
  
  Pages: 15-20
- NAID
  10025784546
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.2006
- Author(s)
  Shimizu A, Nakanishi T, Miyazaki A.
- Journal Title
  
  Mass Spectrom Rev. 25
  
  Pages: 686-712
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin IV as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N.
- Journal Title
  
  Clin.Cancer Res. 12・21
  
  Pages: 6415-6420
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Proteomic-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma.2006
- Author(s)
  Fujita Y, Nakanishi T, Hiramatsu M, Mabuchi H, Miyamoto Y, Miyamoto A, Shimizu A, Tanigawa N
- Journal Title
  
  Clin. Cancer Res. 12・21
  
  Pages: 6415-6420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.2006
- Author(s)
  Shimizu A, Nakanishi T, et al.
- Journal Title
  
  Mass Spectrom Rev 25
  
  Pages: 686-686
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G); 144-146(HC1-3)Lys-Tyr-His→O (g.1413 A→T)] : A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyazaki, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G);144-146(HC1-3)Lys-Tyr-His→0(g.1413 A→T)]:A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  Ayako Miyazaki, Toyofumi Nakanishi, Akira Shimizu, Miki Mizobuchi, Yasuhiro Yamada, Kiyohiro Imai:
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Rapid disease progression correlates with instability of mutant SOD1 in familial ALS.2005
- Author(s)
  T Sato, T Nakanishi, Y Yamamoto, PM Andersen, Y Ogawa, K Fukada, Z Zhou, F Aoike, F Sugai, S Nagano, S Hirata, M Ogawa, R Nakano, T Ohi, T Kato, M Nakagawa, T Hamasaki, A Shimizu, S Sakoda
- Journal Title
  
  Neurology 65(12)
  
  Pages: 1954-1957
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Rapid disease progression correlates with instability of mutant SOD1 in familial ALS.2005
- Author(s)
  T Sato, T Nakanishi, Y Yamamoto, PM Andersen, Y Ogawa, K Fukada, Z Zhou, F Aoike, F Sugai, S Nagano, S Hirata, M Ogawa, R Nakano, T Ohi, T Kato, M Nakagawa, T Hamasaki, A Shimizu, S Sakoda
- Journal Title
  
  Neurology 65・12
  
  Pages: 1954-1957
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI[β141(H19)Leu→Val (g.1404 C→G) ; 144-146(HC1-3)Lys-Tyr-His→0(g.1413 A→T)] :A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyzai, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29・1
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Hb KOCHI [β141(H19)Leu→Val (g.1404 C→G) ; 144-146(HC1-3)Lys-Tyr-His→0 (g.1413 A→T)] : A NEW VARIANT WITH INCREASED OXYGEN AFFINITY.2005
- Author(s)
  A Miyazaki, T Nakanishi, A Shimizu, M Mizobuchi, Y Yamada, K Imai
- Journal Title
  
  Hemoglobin 29(1)
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] New approaches towards laboratory diagnosis of isolated sulfite oxidase deficiency2004
- Author(s)
  J.O.Sass, T Nakanishi, T Sato, A Shimizu
- Journal Title
  
  Annals of Clinical Biochemistry 41
  
  Pages: 157-159
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Effect of mutated transporters associated with antigen-processing 2 on characteristic major histocompatibility complex binding peptides : analysis using electrospray ionization tandem mass spectrometry.2004
- Author(s)
  G.Kageyama, S.Kawano, S.Kanagawa, S.Kondo, M.Sugita, T.Nakanishi, A.Shimizu, S.Kumagai
- Journal Title
  
  Rapid Communications in Mass Spectrometry 18
  
  Pages: 995-1000
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Development of an isotope-dilution mass spectrometric assay for HbA1c based on enzyme-cleaved peptide analysis.2004
- Author(s)
  K Iguchi, T Nakanishi, A Miyazaki, A Shimizu, A Ota
- Journal Title
  
  Journal of Chromatography B 806
  
  Pages: 25-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Modification of cysteine residue in transthyretin and a synthetic peptide, analyses by electrospray ionization mass spectrometry.2004
- Author(s)
  T Nakanishi, T Sato, S Sakoda, M Yoshioka, A Shimizu
- Journal Title
  
  Biochimica et Biophysica Acta 1698
  
  Pages: 45-53
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familianl amyotrophic lateral sclerosis : mass spectrometric and genomic analyses.2004
- Author(s)
  Sato T, Yamamoto Y, Nakanishi T, Fukada K, Sugai F, Zhou Z, Okuno T, Nagano S, Hirata S, Shimizu A, Sakoda S
- Journal Title
  
  J Neurol Sei 218(1-2)
  
  Pages: 79-83
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Identification of two novel mutations in the Cu/Zn superoxide dismutase gene with familial amyotrophic lateral sclerosis : mass spectrometric and genomic analyses.2004
- Author(s)
  Sato T, Yamamoto Y, Nakanishi T, Fukada K, Sugai F, Zhou Z, Okuno T, Nagano S, Hirata S, Shimizu A, Sakoda S
- Journal Title
  
  J Neurol Sci 218(1-2)
  
  Pages: 79-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Review (in press)
- Data Source
  KAKENHI-PROJECT-17590501
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Serum Protein Profile of Rheumatoid Arthritis Treated with Anti-TNF therapy (Infliximab).
- Author(s)
  Takeuchi T, Nakanishi N, Tabushi Y, Hata A, Shoda T, Kotani T, Shimizu A, Takubo T, Makino S, Hanafusa T.
- Journal Title
  
  J Chromatogr B (in press)
- NAID
  10025806140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590502
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590466
[Journal Article] Detection and characterization of variant and modified structures of proteins in blood and tissues by mass spectrometry.
- Author(s)
  Akira Shimizu, Toyofumi Nakanishi, Ayako Miyazaki
- Journal Title
  
  Mass Spectrometry Reviews (in press)
- Data Source
  KAKENHI-PROJECT-16590466

1. NAKANISHI Toyohumi (10247843)

# of Collaborated Projects: 13 results

# of Collaborated Products: 25 results
2. KISHIKAWA Masahiko (40268199)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. NAKAGAWA Toshimasa (30237226)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. HATANAKA Michiyo (50218484)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. MIYAZAKI Ayako (20298772)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. TAKEUCHI Toru (10330078)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. FUJIOKA Shigekazu (20319528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. DEGUCHI Hirofumi (90131341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KITAURA Yasushi (50084950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. UKIMURA Akira (50257862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IKEDA Tsunehiko (70222891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAO Hitoshi (00278540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. GOTO Isao (90330084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 稲井真弥 (90131317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SEYA Tsukasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAGI Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMIZU Akira 清水 章

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

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Principal Investigator

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Analysis of modified structures of transthyretin, elucidation of disease etiology of amyloidosis and application to clinical laboratory testsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the fine structure and the generation process of modified proteins (sulfonate, nitroso, et al.) application to clinical laboratory testPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Principal Investigator

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Principal Investigator

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B cell clone proliferated in HCV infection and V regeon structure of RF correlated to complement clod activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Principal Investigator

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Establishment and practical use of reference method for glyco-haemoglobin by mass spectrometryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of complement cold activation and cryoglobulin formation associated with HCV infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of the mechanism of in-vitro activation of complement and formation of cryoglobulin in the sera from patients with C type hepatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SHIMIZU Akira 清水章