TEZUKA Masakatsu 手塚雅勝

… Alternative Names

手塚雅勝

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Researcher Number	00046294
Other IDs
Affiliation (based on the past Project Information) *help	1999 – 2008: 日本大学, 薬学部, 教授 1986: 静岡薬科大学, 薬学部(放射薬品学), 講師
Review Section/Research Field	Principal Investigator Environmental pharmacy / Environmental pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator AhR / E2F / Ahレセプター / A549細胞 / Arnt / ダイオキシン / dioxin / A549 cells / 3T3-L1 cells / p44 … More / p42 / PPARγ2 / EBPα / C / clonal expansion / 脂肪細胞分化 / 3T3-L1細胞 / uPA mRNA / TCDD / transcription factor / 遺伝子 / 癌 / 環境 / 薬学 / 転写因子 / promoter region analysis / multi-differentiation / human mesenchymal stem cells / プロモーター解析 / 多分化能 / 間葉系幹細胞 / DP2 / CDC10-like / MM-1 / PCNA / CDK4 / ダイオキシン類 / DNAアレイ / adipocyte differentiation / p107 / Rbタンパク質 / SRC-3 / Ah レセプター / 細胞増殖 … More Except Principal Investigator 二次元定量 / イメージング装置 / シンチレータ / 微弱β線 / 生体切片 / 超高感度テレビカメラシステム Less

Transcriptional regulation mechanisms of arylhydrocarbon receptor(AhR), Arnt and E2F genes on proliferation process in A549 cells as promoter activity in carcinogenesis by dioxinPrincipal Investigator
- Principal Investigator
  
  TEZUKA Masakatsu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
Transcriptional regulation of arylhydrocarbon receptor (AhR), Arnt and E2F genes on proliferation process in A549 cells by dioxin and its mechanism.Principal Investigator
- Principal Investigator
  
  TEZUKA Masakatsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
A disturbed regulation of multi-differentiation in human mesenchymal stem cells by dioxin and its mechanismPrincipal Investigator
- Principal Investigator
  
  TEZUKA Masakatsu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
Study on clarification of unregulated gene expression to genome network by dioxin and related compounds using a human alveolar carcinoma cell linePrincipal Investigator
- Principal Investigator
  
  TEZUKA Masakatsu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
Study of gene expression on toxicity of dioxin in cultured cellsPrincipal Investigator
- Principal Investigator
  
  TEZUKA Masakatsu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
生体切片等の^3H,^<14>Cの超高感度テレビカメラシステムによる短時間二次元定量法の
- Principal Investigator
  
  岡田昌二
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Shizuoka College of Pharmacy

All 2009 2008 2007 2006 2005 2003

All Journal Article Presentation

[Journal Article] Characterization of the Molecular Clock in Mouse Peritoneal Macrophages2007
- Author(s)
  M. Hayashi, S. Shimba, M. Tezuka
- Journal Title
  
  Biol. Pharm. Bull. 30(4)
  
  Pages: 621-626
- NAID
  110006271194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590127
[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2 α (HIF-2 α) gene during adipose differentiation in 3T3-L1 cells.2006
- Author(s)
  T.Wada, S.Shimba, M.Tezuka
- Journal Title
  
  Biological ＆ Pharmaceutical Bulletin 29(1)
  
  Pages: 49-54
- NAID
  110005602081
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2alpha (HIF-2alpha) gene during adipose differentiation in 3T3-L1 cells.2006
- Author(s)
  Wada, T., Shimba, S., Tezuka, M.
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 49-54
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2 α (HIF-2 α) gene during adipose differentiation in 3T3-L1 cells2006
- Author(s)
  T.Wada, S.Shimba, M.Tezuka
- Journal Title
  
  Biol. Pharm. Bull. 29(1)
  
  Pages: 49-54
- NAID
  110005602081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] BMAL1,a component of the molecular clock, regulates adipogenesis.2005
- Author(s)
  Shimba, S., Ishii, N., Ohta, Y., Ohno, T., Watabe, Y., Hayashi, M., Wada, T., Aoyagi, T., Tezuka, M.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102
  
  Pages: 12071-12076
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] Brain muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock regulates adipogenesis2005
- Author(s)
  S.Shimba, M.Tezuka et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 102(34)
  
  Pages: 12071-12076
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] Brain and muscle Arnt-like protein- 1(BMAL1), a component of the molecular clock, regulates adipogenesis.2005
- Author(s)
  S.Shimba, M.Tezuka et al.
- Journal Title
  
  Proceedings of the National Academy of Sciences of U.S.A. 102(34)
  
  Pages: 12071-12076
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590109
[Journal Article] Transcriptional Regulation of the AhR Gene during Adipose Differentiation2003
- Author(s)
  S.Shimba, M.Tezuka et al.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 26(9)
  
  Pages: 1266-1271
- NAID
  110003608585
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590114
[Presentation] Ahレセプター(AhR)によるE2Fの転写活性化能の増加とそのメカニズム2009
- Author(s)
  渡部雄一, 榛葉繁紀, 手塚雅勝
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] Ahレセプター(AhR)によるE2Fの転写活性化能の増加とそのメカニズム2009
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  日本薬学界第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 時計遺伝子Bmal1欠損によるメタボッリクシンドローム発症メカニズムの解析2008
- Author(s)
  小川智弘, 手塚雅勝, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] ダイオキシン受容体(AhR)と細胞周期関連因子(E2F)の相互作用2008
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] AhレセプターとE2Fのクロストーク2008
- Author(s)
  渡部雄一, 榛葉繁紀, 手塚雅勝
- Organizer
  B M B 2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] AhレセプターとE2Fのクロストーク2008
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] Ahレセプター/ArntとE2Fのクロストーク2008
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  日本薬学界第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 脂肪細胞においてアラキドン酸は時計遺伝子BMAL1の発現を誘導する2008
- Author(s)
  村林紀雄, 手塚雅勝, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] エネルギー代謝メディエーターとしての乳酸の新たな役割2008
- Author(s)
  小林宗博, 手塚雅勝, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 筋肉細胞における低酸素誘導因子(HIF-1α)によるペルオキシソーム増殖応答性受容体(PPARδ)の制御およびその意義2008
- Author(s)
  和田政孝, 手塚雅勝, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] ダイオキシン受容体(AhR)と細胞周期関連因子(E2F)の相互作用2008
- Author(s)
  渡部雄一, 榛葉繁紀, 手塚雅勝
- Organizer
  フォーラム2008 衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 肺がん由来細胞におけるAhレセプター/ArntとE2Fのクロストーク2008
- Author(s)
  渡部雄一, 手塚雅勝, 他
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 脂肪細胞における遺伝子発現のサーカディアンへの食事の影響2007
- Author(s)
  小川智弘, 手塚雅勝, 他
- Organizer
  第12回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] エネルギー代謝メディエーターとしての乳酸の新たな役割2007
- Author(s)
  小林宗博, 手塚雅勝, 他
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] ダイオキシン受容体(AhR)/Arntと細胞周期関連因子(E2F)の相互作用2007
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  フォーラム2007:衛生薬学・環境トキシコロジー
- Place of Presentation
  大阪
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] アラキドン酸による脂肪細胞特異的な時計遺伝子BMAL1の発現誘導2007
- Author(s)
  村林紀雄, 手塚雅勝, 他
- Organizer
  第14回日本時間生物学会学術大会
- Place of Presentation
  東京
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 筋肉細胞並びに脂肪細胞における低酸素負荷によるPPARδの発現誘導2007
- Author(s)
  和田政孝, 手塚雅勝, 他
- Organizer
  第12回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] アラキドン酸による脂肪細胞特異的な時計遺伝子BMAL1の発現誘導2007
- Author(s)
  村林紀雄, 手塚雅勝, 他
- Organizer
  第12回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 肺がん由来細胞におけるAhレセプター/ArntとE2Fのクロストーク2007
- Author(s)
  渡部雄一、榛葉繁紀、手塚雅勝
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 筋肉細胞における低酸素負荷によるPPARδの発現誘導2007
- Author(s)
  和田政孝, 手塚雅勝, 他
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] エネルギー代謝メディエーターとしての乳酸の新たな役割2007
- Author(s)
  小林宗博, 手塚雅勝, 他
- Organizer
  フォーラム2007衛生薬学・環境トキシコロジー
- Place of Presentation
  大阪
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] ダイオキシン受容体(AhR)/Arntと細胞周期関連因子(E2F)2007
- Author(s)
  渡部雄一, 手塚雅勝, 他
- Organizer
  フォーラム2007衛生薬学・環境トキシコロジー
- Place of Presentation
  大阪
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] エネルギー代謝メディエーターとしての乳酸の新たな役割2007
- Author(s)
  小林宗博, 手塚雅勝, 他
- Organizer
  第12回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 脂肪細胞におけるサーカディアンリズムへの食事の影響2007
- Author(s)
  小川智弘, 手塚雅勝, 他
- Organizer
  第14回日本時間生物学会学術大会
- Place of Presentation
  東京
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 脂肪細胞における遺伝子発現のサーカディアンリズムへの食事の影響2007
- Author(s)
  小川智弘, 手塚雅勝, 他
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] アラキドン酸による脂肪細胞特異的な時計遺伝子BMAL1の発現誘導2007
- Author(s)
  村林紀雄, 手塚雅勝, 他
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] マクロファージ機能ならびに脂肪細胞とのクロストークにおけるBMAL1の役割2007
- Author(s)
  榛葉繁紀, 手塚雅勝, 他
- Organizer
  第12回アディポサイエンス研究会シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2007-08-18
- Data Source
  KAKENHI-PROJECT-19590127
[Presentation] 糖尿病発症のリスクファクターとしての間食ならびに夜食の影響2007
- Author(s)
  榛葉繁紀, 手塚雅勝, 他
- Organizer
  第5回日本セルフメディケーション学会
- Place of Presentation
  船橋
- Year and Date
  2007-10-14
- Data Source
  KAKENHI-PROJECT-19590127

1. 岡田昌二 (40046256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 三輪匡男 (10046287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 松本亮 (70046241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 五島廉輔 (70046275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大須賀慎二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TEZUKA Masakatsu 手塚 雅勝

手塚 雅勝

Research Projects

Research Products

Co-Researchers

Transcriptional regulation mechanisms of arylhydrocarbon receptor(AhR), Arnt and E2F genes on proliferation process in A549 cells as promoter activity in carcinogenesis by dioxinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transcriptional regulation of arylhydrocarbon receptor (AhR), Arnt and E2F genes on proliferation process in A549 cells by dioxin and its mechanism.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A disturbed regulation of multi-differentiation in human mesenchymal stem cells by dioxin and its mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on clarification of unregulated gene expression to genome network by dioxin and related compounds using a human alveolar carcinoma cell linePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of gene expression on toxicity of dioxin in cultured cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生体切片等の^3H,^<14>Cの超高感度テレビカメラシステムによる短時間二次元定量法の

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Characterization of the Molecular Clock in Mouse Peritoneal Macrophages2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2 α (HIF-2 α) gene during adipose differentiation in 3T3-L1 cells.2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2alpha (HIF-2alpha) gene during adipose differentiation in 3T3-L1 cells.2006

Author(s)

Journal Title

Data Source

[Journal Article] Transcriptional regulation of the hypoxia inducible factor-2 α (HIF-2 α) gene during adipose differentiation in 3T3-L1 cells2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] BMAL1,a component of the molecular clock, regulates adipogenesis.2005

Author(s)

Journal Title

Data Source

[Journal Article] Brain muscle Arnt-like protein-1 (BMAL1), a component of the molecular clock regulates adipogenesis2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Brain and muscle Arnt-like protein- 1(BMAL1), a component of the molecular clock, regulates adipogenesis.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transcriptional Regulation of the AhR Gene during Adipose Differentiation2003

Author(s)

Journal Title

NAID

TEZUKA Masakatsu 手塚雅勝

手塚雅勝