HAMASAKI Naotaka 濱崎直孝

… Alternative Names

Researcher Number	00091265
Other IDs
Affiliation *help	2014 – 2016 : 長崎国際大学, 薬学部, 客員教授 2013 – 2015 : 長崎国際大学, 薬学部, 名誉教授 2009 – 2014 : Nagasaki International University, 薬学部, 教授 2011 : 長崎国際大学 2009 : 長崎国際大, 薬学部, 教授 … More
Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry Except Principal Investigator Pathological medical chemistry / Laboratory medicine / Applied pharmacology / Biophysics / General medical chemistry / Pathological medical chemistry / Digestive surgery / General medical chemistry … More
Keywords	Principal Investigator バンド3蛋白質 / ポリトピック型膜蛋白質 / 膜蛋白質 / Hydrophilic Connector Loop / 陰イオン透過活性中心 / 膜内架橋 / マルチスパン / スチルベン化合物 / peptide interaction / 赤血球膜 … More Except Principal Investigator 赤血球膜 / プロテインS / 陰イオン透過系 / 深部静脈血栓症 / 血栓性素因 / バンド3蛋白質 / 血栓症 / 透過活性中心 / 免疫検査 / 日本人の血栓性素因 / Band 3 Protein / ホモジニアスアッセイ / Band3 / 膜タンパク質 / D-loop / Red Cell Membrane / 磁気マーカー / AE1 / プロテインC / Band 3 / ホスホエノールピルビン酸 / 赤血球 / ヒスチジン残基 / バンド3 / ピリドキサルリン酸 / 1次構造決定 / neovasculalization / factor V Leiden / ESTROGEN / NaBH_4 / 阻害剤結合部位 / 膜蛋白質の高次構造 / 磁気的免疫検査システム / Transmembrane protein / エネルギーチャージ / 細胞増殖 / 膜貫通領域 / Primary Structure / R-ループ / Protein S / ホモジニアス / Thrombophilia / X線結晶構造解析 / protein C / MPP+ / phospholipids / 医療・福祉 / re-epithelialization / 陰イオン透過 / protein S / 電子顕微鏡 / Transmembrane spanning region / 疎水性膜貫通領域 / warm ischemia of the liver / 韓国 / 赤血球膜蛋白質 / 肝虚血再環流 / Hydrophilic connector loop / ホスホエノールピルビン酸の細胞膜透過 / 疏水性膜貫通領域 / nucleoid / プロテインS分子異常 / ミトコンドリア / Active center / Peptide-lipid interaction / 血栓症の病因解析 / 細胞増殖因子 / 陰イオン透過活性中心 / バンド3蛋白質の構造変化 / 英国 / ミトコンドリアDNAヌクレオイド構造 / 膜蛋白質の構造 / 蛋白質 / D-ループ / Holliday構造 / ポリトピック型膜蛋白質 / 解糖系 / 膜蛋白質の一次構造決定 / Mediated transport / ペプチド構造 / 生体分子 / mitochondrial DNA / 抗原抗体反応 / 日本人の血栓症素因 / バンド３ / 肝虚血・再環流障害 / 内科 / Transport Active Center / ハンガリー / 膜蛋白質構造解析 / Inhibitor Binding Site / Anion Transport / Prolein S / Structure of transmembrane protein / 二次元結晶 / Anion transport system / 中国 / 表皮形成 / 遺伝的背景 / mtSSB / Phosphoenolpyruvate Transport / ミトコンドリアDNA / 赤血球膜タンパク質 / 膜蛋白質の構造解析 / ホスホエノーピルビン酸 / 膜貫通ペプチドの一次構造 / Protein C / gene analysis / ラット / 肉芽形成 / protein C gene mutation / Structure of Membrane Domain / 溶血性貧血 / ミトコンドリア転写因子A / mtTFA / ProteinS / 膜タンパク質の一次構造 / hepatic energy / Holliday structure / 栄養学 / ProteinC / 肝虚血再還流 / 結晶化 / ホスホエノールピルビン / PEP / 肝虚血再還流障害 / 構造機能相関 / プロテインS比活性 / ホリデー構造 / diabetic skin ulcer / Band3タンパク質 / プロテインS徳島 / Protease Sensitivity / 血管新生 / 透過媒介蛋白質 / Structure-Function Relationship / cell proliferation / 血栓症治療薬 / THROMBOSIS / 立体構造予測 / 結晶構造解析 / 生体分子医学 / DIDS / ホスホエノールピルビン酸透過 / Protein S凝固制御系因子 / 遺伝子多系 / 電子線構造解析 / Protein S分子の高次構造変化 / シンガポール / Transmembrane / 国際情報交換 / 陰イオン透過機構 / 抗体 / 一次構造解析 / 膜リン脂質 / プロテアーゼ感受性 / 膜貫通ペプチド / ホルモン補充療法 / 分子異常性 / 二次元結晶化 / Anion Transport Mechanism / protein S gene mutation / 無キリン酸透過系 / Erythrocyte membrane / tertiary structure of protein S / アジア人の血栓性素因 / コンフォーメーション変化 / 電子線結晶構造解析 / Conformational Change / growth factors / プロテインC分子異常 / アミノ酸配列 / DNA replication / 陰イオン透過の分子機構 / Deep vein thrombosis / プロテインＳ / 膜貫通ドメインのカテゴリー分類 / Histidine residue / R-loop / phosphoe nolpyruvic acid (PEP) / thrombophilia / 国際学術調査 / 磁気検出 / 予防治療戦略 / ピリドキサルリン酸アフィニティラベル / granulation tissue formation / 膜貫通タンパク質 / バンド3タンパク質 / SQUID / PROTEINS / protein S_<Tokushima> / 比活性 / 電子線結晶学 / HORMONE REPLACEMENT THERAPY / Hemolytic Anemia / 細胞膜の物質透過 / Diethylpyro carbonate / 静脈血栓塞栓症 / TFAM / 膜内ペプチドの一次構造決定 / 発症要因 / エストロゲン / Amino acid sequence / Javanese thrombophilia / phosphoenolpyruvate / Phosphate transport system / 膜輸送体 / cell activating agents / ライデン型第5因子 / ミトコンドリアDNA複製 / polymorphism / X線構造解析 / 細胞賦活剤 / mitochondria / 糖尿病性皮膚潰瘍 / Polytopic membrane Protein / 遺伝子解析 / risk factor for Japanese Thrombophilia / アニオントランスポーター / 遺伝学 / Phosphoenolpyruvate transport across the cell membrane Less

磁気検出法によるホモジニアスアッセイの深化と微量血液検査システムの開発Ongoing
- Principal Investigator
  
  隈博幸
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki International University
アジア人固有の血栓症発症要因の病態解明と新たな予防治療戦略の確立Ongoing
- Principal Investigator
  
  津田博子
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nakamura Gakuen College
Studies on thrombophilia -deficiency and mutation of protein S-Principal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagasaki International University
Development of homogenous and quantitative immunoassay system with magnetic detection
- Principal Investigator
  
  KUMA Hiroyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki International University
Crystal structure of human Band3 (anion exchanger)
- Principal Investigator
  
  KOBAYASHI TAKUY
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Structural analysis of band 3 in the membrane
- Principal Investigator
  
  HIRAI Teruhisa
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
  The Institute of Physical and Chemical Research
Structural Study on Human Red Cell Band 3 Protein, AE1.Principal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagasaki International University
Japanese Thrombophilia : Diagnoses and PreventionPrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nagasaki International University
A novel therapeutic strategy for treatment of diabetic skin ulcer using phosphoenolpyruvic acid
- Principal Investigator
  
  IRIE Tetsumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kumamoto University
Development of a new assay system for protein S/protein C and treatment of thrombophilia.Principal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  KYUSHU UNIVERSITY
Investigation of a novel pathogenesis of thrombosis-regulation of protein S by sex hormones and its abnormality-
- Principal Investigator
  
  OHNAKA Keizo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kyushu University
Risk Factors for Asian ThrombophiliaPrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyushu University
A role of Holliday structure in mitochondrial genome maintenance
- Principal Investigator
  
  KANG Dongchon
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Structure and Functional Relationship of Band 3 ProteinPrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  KYUSHU UNIVERSITY
アニオントランスポーターの分子機序:バンド3蛋白質の構造解析と分子機序の解明Principal Investigator
- Principal Investigator
  
  濱崎直孝
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Structural Study of Transmembrane Domain of Band 3 ProteinPrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
Phshoenol/pyruvate prevents the decline in hepatic ATP and energy charge afte ischemia and reperfusion injyury in rats
- Principal Investigator
  
  YAMAGUCHI Koji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyushu University
アニオントランスポーターの分子機序:アニオンで誘発される構造変化と透過機構Principal Investigator
- Principal Investigator
  
  濱崎直孝, 浜崎直孝
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
バンド3蛋白質で媒介される陰イオン透過の分子機構に関する蛋白質化学的研究Principal Investigator
- Principal Investigator
  
  濱崎直孝, 浜崎直孝
- Project Period (FY)
  1993 – 1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
バンド3蛋白質の陰イオン透過活性中心について、その構造解析と病態解析Principal Investigator
- Principal Investigator
  
  浜崎直孝
- Project Period (FY)
  1993 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
陰イオンチャンネルの分子機構に関する蛋白質化学的研究Principal Investigator
- Principal Investigator
  
  濱崎直孝, 浜崎直孝
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka University
Molecular Mechanisms of Anion Transport System across the Biological MembranePrincipal Investigator
- Principal Investigator
  
  OKUBO Kenshi, 浜崎直孝, 濱崎直孝
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Fukuoka University
Molecular Mechanisms of Anion Transport System across the Biological MembranesPrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotake, 浜崎直孝
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukuoka University
赤血球膜陰イオン透過活性中心ペプチドの同定・分離・精製及びその構造解析Principal Investigator
- Principal Investigator
  
  濱崎直孝, 浜崎直孝
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukuoka University
Transport of Phosphoenolpyruvate across the Biological MembranePrincipal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka, 浜崎直孝, 濱崎直考
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Fukuoka University
PROTEIN CHEMISTRY AND BIOCHEMICAL STUDY ON THE ANION TRANSPORT SYSTEM IN HUMAN ERYTHROCYTE MEMBRANES.Principal Investigator
- Principal Investigator
  
  HAMASAKI Naotaka
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Fukuoka University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation Book

[Book] 医療の羅針盤　臨床検査を語る2014
- Author(s)
  濱崎直孝、上平憲
- Total Pages
  125
- Publisher
  長崎文献社
- Data Source
  KAKENHI-PROJECT-25460398
[Book] Quality of Diagnostic Samples (3rd Edition)2009
- Author(s)
  Hamasaki N, et al.
- Total Pages
  124
- Publisher
  German United Society for Clinical Chemistry and Laboratory Medicine
- Data Source
  KAKENHI-PROJECT-21590322
[Book] Recent Advances in Thrombosis and Hemostasis(Tanaka, K., Davie, EW., eds)2008
- Author(s)
  Hamasaki, N, et. al.
- Total Pages
  650
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-18390173
[Book] Recent Advanes in Thrombosis and Hemostasis (Tanaka, K., Davie, EW., eds)2008
- Author(s)
  Hamasaki, N., et. al.
- Publisher
  Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390173
[Journal Article] Multianalyte Conventional Reference Material (MacRM): A Useful Tool for Nationwide Standardization of Laboratory Measurements for Medical Care-A Model Study in Japan2016
- Author(s)
  Shinohara K, Hamasaki N, Takagi Y, Yatomi Y, Kikuchi H, Hosogaya S, Kawai Y, Miyachi H, Kaneko K, Miyajima Y, Matsumoto H, Yamamoto Y, Iwagami M, Osawa S, Umeda M, Koide H, Yoshimura D, Kato H
- Journal Title
  
  Clinical Chemistry
  
  Volume : 62 Pages : 392-406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08632, KAKENHI-PROJECT-25460398, KAKENHI-PROJECT-26305027
[Journal Article] Multianalyte Conventional Reference Material (MacRM): A Useful Tool for Nationwide Standardization of Laboratory Measurements for Medical Care-A Model Study in Japan2016
- Author(s)
  Shinohara K, Hamasaki N, Takagi Y, Yatomi Y, Kikuchi H, Hosogaya S, Kawai Y, Miyachi H, Kaneko K, Miyajima Y, Matsumoto H, Yamamoto Y, Iwagami M, Osawa S, Umeda M, Koide H, Yoshimura D, Kato H
- Journal Title
  
  Clinical Chemistry
  
  Volume : 62 Pages : 392-406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08632, KAKENHI-PROJECT-25460398, KAKENHI-PROJECT-26305027
[Journal Article] Crystal structure of the anion exchanger domain of human erythrocyte band 32015
- Author(s)
  Arakawa T, Kobayashi-Yurugi T, Alguel Y, Iwanari H, Hatae H, Iwata M, Abe Y, Hino T, Ikeda-Suno C, Kuma H, Kang D, Murata T, Hamakubo T, Cameron AD, Kobayashi T, Hamasaki N, Iwata S
- Journal Title
  
  Science
  
  Volume : 350 Pages : 680-684
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08632, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25253041, KAKENHI-PROJECT-25460398, KAKENHI-PROJECT-26305027, KAKENHI-PROJECT-25711004
[Journal Article] プロテインS比活性測定：易血栓症状態予知マーカー2015
- Author(s)
  濱崎直孝
- Journal Title
  
  臨床病理
  
  Volume : 63 Pages : 1412-1418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460398
[Journal Article] プロテインS比活性測定：易血栓症状態予知マーカー2015
- Author(s)
  濱崎直孝
- Journal Title
  
  臨床病理
  
  Volume : 63 Pages : 1412-1418
- Open Access
- Data Source
  KAKENHI-PROJECT-26305027
[Journal Article] Crystal structure of the anion exchanger domain of human erythrocyte band 32015
- Author(s)
  Arakawa T, Kobayashi-Yurugi T, Alguel Y, Iwanari H, Hatae H, Iwata M, Abe Y, Hino T, Ikeda-Suno C, Kuma H, Kang D, Murata T, Hamakubo T, Cameron AD, Kobayashi T, Hamasaki N, Iwata S
- Journal Title
  
  Science
  
  Volume : 350 Pages : 680-684
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08632, KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25253041, KAKENHI-PROJECT-25460398, KAKENHI-PROJECT-26305027, KAKENHI-PROJECT-25711004
[Journal Article] 国際的な標準化活動とJSCC2014
- Author(s)
  濱崎　直孝
- Journal Title
  
  臨床検査
  
  Volume : 58 Pages : 150-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590716
[Journal Article] 国際的な標準化活動とJSCC2014
- Author(s)
  濱崎　直孝
- Journal Title
  
  臨床検査
  
  Volume : 58 Pages : 150-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460398
[Journal Article] 国際的な標準化活動とJSCC2014
- Author(s)
  濱崎直孝
- Journal Title
  
  臨床検査
  
  Volume : 58 Pages : 150-155
- Data Source
  KAKENHI-PROJECT-26305027
[Journal Article] Activated protein C anticoagulant system dysfunction and thrombophilia in Asia2013
- Author(s)
  Hamasaki N, Kuma H, Tsuda H.
- Journal Title
  
  Ann. Lab. Med.
  
  Volume : 33 Pages : 8-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590905, KAKENHI-PROJECT-24590716, KAKENHI-PROJECT-25460398
[Journal Article] Beneficial effect of EPA (20:5 n-3 PUFA) on preventing venous thromboembolism: a rat tail thrombosis model experiment.2013
- Author(s)
  Kuma H, Nagashima R, Hatae H, Tsuda T, Hamasaki N
- Journal Title
  
  Thromb Res
  
  Volume : 131(1) Pages : 107-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590716, KAKENHI-PROJECT-25460398
[Journal Article] Phosphoenolpyruvate (PEP), a glycolytic intermediates with antioxidant activity; the potential for cellular and organ protective application2013
- Author(s)
  Kondo Y, Ishitsuka Y , Kadowaki D, Fukumoto Y, Miyamoto Y, Irikura M, Hirata S, Sato K, Maruyama T, Hamasaki N, and Irie T
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume : 65 Pages : 390-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590642, KAKENHI-PROJECT-23790603, KAKENHI-PROJECT-25460398
[Journal Article] Molecular basis of protein S deficiency in China.2013
- Author(s)
  Tang L, Jian XR, Hamasaki N, Guo T, Wang HF, Lu X, Wang QY, Hu Y
- Journal Title
  
  Am J Hematol
  
  Volume : 88(10) Pages : 899-905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460398
[Journal Article] Comparative effects of phosphoenolpyruvate (PEP), a glycolytic intermediate, as an organ preservation agent with glucose and N-acetylcysteine against organ damage during cold storage of mouse liver and kidney2013
- Author(s)
  Ishitsuka Y, Fukumoto Y, Kondo Y, Irikura M, Kadowaki D, Narita Y, Hirata S, Moriuchi H, Maruyama T, Hamasak N, Irie T
- Journal Title
  
  ISRN Pharmacology
  
  Volume : 2013 Pages : 375825-375825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590642, KAKENHI-PROJECT-23790603, KAKENHI-PROJECT-25460398
[Journal Article] Characterization of magnetic markers for liquid-phase immunoassays using Brownian relaxation2012
- Author(s)
  K.Enpuku, et al
- Journal Title
  
  Jpn.J.Appl.Phys.
  
  Volume : 51 Pages : 23002-23002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360199, KAKENHI-PROJECT-24590716
[Journal Article] Arg901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding2012
- Author(s)
  Takazaki, S, Abe, Y, Yamaguchi T, Yagi M, Ueda T, Kagn D, Hamasaki N
- Journal Title
  
  Biochem.Biophy.Acta
  
  Volume : 1819 Pages : 658-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590322, KAKENHI-PROJECT-22249018, KAKENHI-PROJECT-23570140, KAKENHI-PROJECT-24659281
[Journal Article] Arg901 in the AE1 C-terminal tail is involved in conformational change but not in substrate binding2012
- Author(s)
  Takazaki, S, Abe, Y, Yamaguchi T, Yagi M, Ueda T, Kagn D, and Hamasaki N.
- Journal Title
  
  Biochem. Biophy. Acta
  
  Volume : 1818 Pages : 658-665
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Topology models of anion exchanger 1 that incorporate the antiparallel V-shaped motifs found in the EM structure2011
- Author(s)
  Hirai T, Hamasaki N., Yamaguchi T, Ikeda Y.
- Journal Title
  
  Bioche.Cell Biol.
  
  Volume : 89 Pages : 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Topology models of anion exchanger 1 that incorporate the anti-parallel V-shaped motifs found in the EM structure2011
- Author(s)
  Hirai T, Hamasaki N., Yamaguchi T, and Ikeda Y.
- Journal Title
  
  Bioche. Cell Biol
  
  Volume : 89 Pages : 1-9
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Structure of the Membrane Domain of Human Erythrocyte Anion Exchanger 1 Revealed by Electron Crystallography2010
- Author(s)
  Yamaguchi T., Ikeda Y., Abe Y., Kuma H., Kang D., Hamasaki N., and Hirai T.
- Journal Title
  
  J. Mol. Biol
  
  Volume : 397 Pages : 179-189
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Helical image reconstruction of outward-open human erythrocyte band 3 membrane domain in tubular crystals2010
- Author(s)
  Yamaguchi T., Fujii T., Abe Y., Hirai T., Kang D., Namba K., Hamasaki N., and Mitsuoka K.
- Journal Title
  
  J. Struct. Biol
  
  Volume : 169(3) Pages : 406-412
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Mutation of His 834 in human anion exchange 1 affects substrate binding2010
- Author(s)
  Takazaki, S, Abe, Y, Yamaguchi T, Yagi M, Ueda T, Kagn D, and Hamasaki N.
- Journal Title
  
  Biochem. Biophy. Acta
  
  Volume : 1798 Pages : 903-908
- Data Source
  KAKENHI-PROJECT-21590322
[Journal Article] Clinical Role of Protein S Deficiency in Asian Population.2008
- Author(s)
  Hamasaki, N., et. al.
- Journal Title
  
  Recent Advances in Thrombosis and Hemostasis(Tanaka, K., Davie, EW., eds)(Total 650 pages)
  
  Pages : 597-613
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390173
[Journal Article] Recent Advances2008
- Author(s)
  Hamasaki, N., et. al.
- Journal Title
  
  Thrombosis and Hemostasis(Tanaka, K., Davie, EW., eds), Springer
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390173
[Journal Article] Characterization of two novel mutations of the antithrombin gene observed in Japanese thrombophilic patients.2005
- Author(s)
  Kurihara M, Watanabe, K, Inoue S, Wada Y, Ono M, Wakiyama M, Iida H, Kinoshita S, Hamasaki N.
- Journal Title
  
  Thrombosis Research 115・5
  
  Pages : 351-358
- Data Source
  KAKENHI-PROJECT-16390165
[Journal Article] Analytical goals for coagulation tests based on biological variation.2004
- Author(s)
  Wada Y, Kurihara M, Toyofuku M, Kawamura M, Iida H, Kayamori Y, Kinoshita S, Hamasaki N.
- Journal Title
  
  Clin.Chem.Lab.Med. 42・1
  
  Pages : 79-83
- Data Source
  KAKENHI-PROJECT-16390165
[Journal Article] Development of a new colorimetric method for protein S activity measurement.2004
- Author(s)
  Tsuda, T., H.Yoshimura, N.Hamasaki
- Journal Title
  
  Clin Chem Lab Med 42(3)
  
  Pages : 350-352
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390165
[Presentation] 凝固亢進状態(易血栓症状態)の新しい判定法：プロテインS 比活性測定2016
- Author(s)
  濱崎直孝
- Organizer
  第38回日本血栓止血学会
- Place of Presentation
  奈良春日野国際フォーラム
- Year and Date
  2016-06-18
- Invited
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] プロテインS 比活性測定：―検査データから診断する易血栓症状態―2016
- Author(s)
  濱崎直孝
- Organizer
  第38回日本血栓止血学会
- Place of Presentation
  奈良春日野国際フォーラム
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] 静脈血栓塞栓症発症危険要因の定量分析2015
- Author(s)
  濱崎直孝
- Organizer
  第28 回バイオメディカル分析科学シンポジウム
- Place of Presentation
  長崎大学文教キャンパス
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] APC凝固制御異常と血栓性素因2014
- Author(s)
  濱崎　直孝
- Organizer
  第36回日本血栓止血学会プロテインS研究会シンポジウム
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-24590716
[Presentation] APC凝固制御異常と血栓性素因2014
- Author(s)
  濱崎　直孝
- Organizer
  第36回日本血栓止血学会プロテインS研究会シンポジウム
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] APC凝固制御異常と血栓性素因2014
- Author(s)
  濱崎直孝
- Organizer
  第36回日本血栓止血学会学術集会、プロテインS研究会シンポジウム
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-30
- Invited
- Data Source
  KAKENHI-PROJECT-26305027
[Presentation] Homogenous quantitative analysis of human parathyroid hormone by use of magnetic markers and SQUID magnetometer2013
- Author(s)
  Maeda C, Hisamatsu K, Mitsuse, K, Egashira, S, Hamasaki, N, Enpuku, K, Kuma, H
- Organizer
  International Federation of Clinical Chemistry
- Place of Presentation
  イタリア・ミラノ
- Data Source
  KAKENHI-PROJECT-24590716
[Presentation] 血栓モデルラットを用いた不飽和脂肪酸の血栓症予防効果の検討2013
- Author(s)
  波多江日成子、隈　博幸、濱崎直孝
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形国際ホテル
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] Benefical effect of phospahtidylethanolamine on preventing venous thromboembolism: A rat tail thrombosis model experiment2013
- Author(s)
  Ayaka Higashijima, Sakiko Mizunoe, Kozue Nakahara, Hiroyuki Kuma, Hinako Hatae and Naotaka Hamasaki
- Organizer
  IFCC EuroMedlab
- Place of Presentation
  イタリア・ミラノ
- Data Source
  KAKENHI-PROJECT-25460398
[Presentation] 2者タンパク質間を認識するライト抗体を利用したバンド3-グリコフォリンA複合体の精製2012
- Author(s)
  池田洋平、波多江日成子、隈博幸、濱崎直孝、平井照久
- Organizer
  日本生物物理学会
- Place of Presentation
  名古屋大学東山キャンパス
- Data Source
  KAKENHI-PROJECT-23570201
[Presentation] 我が国における臨床検査標準化の現状2010
- Author(s)
  濱崎直孝
- Organizer
  第50回日本臨床化学会学術集会
- Place of Presentation
  山梨県民文化ホール
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21590322
[Presentation] Standardization of clinical laboratory measurement in Japan2007
- Author(s)
  濱崎直孝
- Organizer
  11th Asian-Pacific Congress of Clinical Biochemistry(Plenary Lecturer IV)
- Place of Presentation
  Beijing,China
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-18390173
[Presentation] Standardization of clinical laboratory measurement in Japan2007
- Author(s)
  Naotaka HAMASAKI
- Organizer
  11th Asian-Pacific Congress of Clinical Biochemistry(Plenary Lecture IV)
- Year and Date
  2007-10-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390173
[Presentation] Standardization of clinical laboratory measurement in Japan2007
- Author(s)
  濱崎直孝
- Organizer
  11th Asian-Pacific Congress of Clinical Biochemistry(Plenary Lecture IV)
- Place of Presentation
  Beijing,China
- Year and Date
  2007-10-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390173
[Presentation] Topology models of anion exchanger 1 that incorporate the anti-parallel V-shaped motifs found in the EM structure
- Author(s)
  Hirai T, Hamasaki N., Yamaguchi T, and Ikeda Y.
- Organizer
  CSBMCB 53^<rd> Annual Meeting on Membrane Protein in Health and Disease
- Data Source
  KAKENHI-PROJECT-21590322
[Presentation] 静脈血栓塞栓症の予防対策としての新しい検査法
- Author(s)
  濱崎直孝
- Organizer
  第27回日本臨床検査自動化学会春季セミナー
- Place of Presentation
  くまもと森都心プラザ
- Invited
- Data Source
  KAKENHI-PROJECT-25460398

1. KANG Donchon (80214716)

# of Collaborated Projects : 5results

# of Collaborated Products : 3results
2. KUMA Hiroyuki (40435136)

# of Collaborated Projects : 5results

# of Collaborated Products : 9results
3. OKUBO Kenshi (40194097)

# of Collaborated Projects : 5results

# of Collaborated Products : 0results
4. KOBAYASHI Takuya (20311730)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. HIRAI Teruhisa (10450412)

# of Collaborated Projects : 2results

# of Collaborated Products : 6results
6. ABE Yoshito (60315091)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
7. IWATA So (60452330)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. HATAE Hinako (00551582)

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
9. YAMAGUCHI Koji (50191226)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. CHIJIIWA Kazuo (90179945)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. IZUHARA Kinji (00270463)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. MUTA Koichiro (50229928)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
13. ISHIBASHI Tatsuro (30150428)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
14. OHNAKA Keizo (30325518)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
15. TAKAYANAGI Ryoichi (30154917)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. IRIE Tetsumi (60150546)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
17. MORIUCHI Hiroshi (90244144)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. INOUE Yuji (30264310)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 津田博子 (30180003)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
20. 古森公浩 (40225587)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
21. 河野洋一 (50152989)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
22. TSUDA Tomohide

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
23. NAITO Tokio

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
24. IGIMI Hirotsune

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
25. HARASAKI Hiroaki

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
26. BRUCE Lesley

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
27. TANNER Michael

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
28. OMACHI Akira

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
29. 森朗

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
30. JENNINGS Mic

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
31. JENNINGS Michael l.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
32. MICHAEL L.Je

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
33. 亀岡宣久

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
34. TONNER Micka

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
35. BLOOMBERG Gr

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
36. 濱崎直考

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
37. RICHARD J.La

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
38. LABOTKA Lichard J.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
39. RICHARD J La

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
40. ENPUKU Keiji

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
41. TAKAZAKI Shinya

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
42. Hino Tomoya

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
43. ISHITSUKA Yoichi

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
44. 浜窪隆雄

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
45. 岩成宏子

# of Collaborated Projects : 0results

# of Collaborated Products : 2results

HAMASAKI Naotaka 濱崎 直孝

浜崎 直孝 ハマサキ ナオタカ

Research Projects

Research Products

Co-Researchers

磁気検出法によるホモジニアスアッセイの深化と微量血液検査システムの開発Ongoing

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アジア人固有の血栓症発症要因の病態解明と新たな予防治療戦略の確立Ongoing

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Studies on thrombophilia -deficiency and mutation of protein S-Principal Investigator

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Development of homogenous and quantitative immunoassay system with magnetic detection

Principal Investigator

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Crystal structure of human Band3 (anion exchanger)

Principal Investigator

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Structural analysis of band 3 in the membrane

Principal Investigator

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Structural Study on Human Red Cell Band 3 Protein, AE1.Principal Investigator

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Japanese Thrombophilia : Diagnoses and PreventionPrincipal Investigator

Principal Investigator

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A novel therapeutic strategy for treatment of diabetic skin ulcer using phosphoenolpyruvic acid

Principal Investigator

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Development of a new assay system for protein S/protein C and treatment of thrombophilia.Principal Investigator

Principal Investigator

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Investigation of a novel pathogenesis of thrombosis-regulation of protein S by sex hormones and its abnormality-

Principal Investigator

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Risk Factors for Asian ThrombophiliaPrincipal Investigator

Principal Investigator

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A role of Holliday structure in mitochondrial genome maintenance

Principal Investigator

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HAMASAKI Naotaka 濱崎直孝

浜崎直孝ハマサキナオタカ