NUKAYA Haruo 糠谷東雄

… Alternative Names

Researcher Number	00094342
Other IDs
Affiliation (Current)	2018 : 静岡県立大学, 食品栄養科学部, 研究員
Affiliation (based on the past Project Information) *help	2014 : 静岡県立大学, 食品栄養科学部, 研究員 2010 – 2014 : 静岡県立大学, 食品栄養科学部, 客員教授 2009 : 静岡県立大学, 食品栄養科学部, 客員共同研究員
Review Section/Research Field	Except Principal Investigator Eating habits, studies on eating habits
Keywords	Except Principal Investigator 生活習慣病 / コレステロール / 分析科学 / 脂質 / 炎症 / オゾン酸化 / 好中球 / ミエロペルオキシダーゼ / 栄養学 / アルデヒド / 健康と食生活 / オゾン酸化コレステロール

Ozone-oxidized cholesterols as biomarkers for metabolic syndrome and life-style related diseases
- Principal Investigator
  
  OHSHIMA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Shizuoka
Elucidations of the mechanisms for the formation of cholesterol-ozonolysis products in inflamed tissues, their biological activities and involvement in disease development
- Principal Investigator
  
  OHSHIMA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  University of Shizuoka

All 2015 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] Comprehensive analysis of the lipophilic reactive carbonyls present in biological specimens by LC/ESI-MS/MS2015
- Author(s)
  Tomono S, Miyoshi N, Ohshima H
- Journal Title
  
  J Chromatogrphy B
  
  Volume : 988 Pages : 149-156
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300257
[Journal Article] Implications of cholesterol autoxidation products in the pathogenesis of inflammatory diseases.2014
- Author(s)
  Miyoshi N, Iuliano L, Tomono S, Ohshima H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume : 446 Pages : 702-708
- DOI
  10.1016/j.bbrc.2013.12.107
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-24700838
[Journal Article] Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein.2013
- Author(s)
  Miyoshi N, Iwasaki N, Tomono S, Higashi T, Ohshima H.
- Journal Title
  
  Free Radic. Biol. Med.
  
  Volume : 60 Pages : 73-79
- DOI
  10.1016/j.freeradbiomed.2013.01.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-24700838
[Journal Article] Cytotoxic effects of secosterols and its derivatives on several cultured cells.2013
- Author(s)
  Tomono S
- Journal Title
  
  Biosci. Biotechnol.Biochem.
  
  Volume : 77 Pages : 651-653
- DOI
  10.1271/bbb.120758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650486, KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-24700838
[Journal Article] Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein.2013
- Author(s)
  Miyoshi N
- Journal Title
  
  Free Radic Biol Med
  
  Volume : In press Pages : 143-149
- DOI
  10.3164/jcbn.11-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650486, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-23790747, KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24700838
[Journal Article] Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde : Implications for vascular and neurodegenerative diseases.2012
- Author(s)
  Lai YL, Tomono S, Miyoshi N, Ohshima H
- Journal Title
  
  J.Clin.Biochem.Nutr.
  
  Volume : 50 Pages : 84-9
- DOI
  10.3164/jcbn.11-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300280, KAKENHI-PROJECT-24300257
[Journal Article] Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.2012
- Author(s)
  Miyoshi, N., Yonemochi, T., Tomono, S., Fukutomi, R., Nakamura, Y., Ohshima, H.
- Journal Title
  
  Anal Biochem
  
  Volume : 429(2) Pages : 124-131
- DOI
  10.1016/j.ab.2012.07.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580129, KAKENHI-PROJECT-23650486, KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-24700838
[Journal Article] Analysis of Nε-ethyllysine in human plasma proteins by gas chromatography-negative ion chemical ionization/mass spectrometry as a biomarker for exposure to acetaldehyde and alcohol.2012
- Author(s)
  Mabuchi R., et al.
- Journal Title
  
  Alcohol. Clin. Exp. Res.
  
  Volume : (印刷中) Pages : 1013-1020
- DOI
  10.1111/j.1530-0277.2011.01705.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680052, KAKENHI-PROJECT-23650486, KAKENHI-PROJECT-24300257, KAKENHI-PROJECT-24680075, KAKENHI-PROJECT-22350070
[Journal Article] Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway.2011
- Author(s)
  Tomono S, Miyoshi N, Shiokawa H, Iwabuchi T, Aratani Y, Higashi T, Nukaya H, Ohshima H.
- Journal Title
  
  J.Lipid Res.
  
  Volume : 52 Pages : 87-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300280
[Journal Article] Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway2011
- Author(s)
  Tomono S, Miyoshi N, Shiokawa H, Iwabuchi T, Aratani Y, Higashi T, Nukaya H, Ohshima H
- Journal Title
  
  J. Lipid Res.
  
  Volume : 52 Pages : 87-97
- DOI
  10.1194/jlr.m006775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300280
[Presentation] Denaturation of cellular proteins induced by secosterol aldehydes2014
- Author(s)
  Noriyuki Miyoshi, Susumu Tomono, Hiroshi Ohshima.
- Organizer
  SFRR-international 2014
- Place of Presentation
  Kyoto,Japan
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Global analysis of reactive carbonyls formed in neuronal PC-12 cells by exposed to amyloid-beta2014
- Author(s)
  Susumu Tomono, Misa Nagasawa, Noriyuki Miyoshi, Hiroshi Ohshima.
- Organizer
  SFRR-international 2014
- Place of Presentation
  Kyoto,Japan
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Identification of carcinogenic compounds formed by chronic ethanol feeding in feces of mice2013
- Author(s)
  Shoko Hirukawa, Shunsuke Sanada, Noriyuki Miyoshi, Hiroshi Ohshima.
- Organizer
  静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Conprehensive analytical method for lipophilic reactive carbonyl compounds in biological samples2013
- Author(s)
  Susumu Tomono, Noriyuki Miyoshi, Hiroshi Ohshima.
- Organizer
  SFRR-Europe 2013 Conference
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Search as novel diagnostic biomarkers for fecal small molecules responsible for metabolic syndrome in ob/ob mice2013
- Author(s)
  Shunsuke Sanada, Shoko Hirukawa, Noriyuki Miyoshi, Hiroshi Ohshima.
- Organizer
  静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Acetaldehyde-modification of dehydrogenase/reductase member 2 decrease its binding to Mdm22013
- Author(s)
  Yuji Yamada, Aya Kurita, Susumu Tomono, Noriyuki Miyoshi, Hiroshi Ohshima.
- Organizer
  静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] Cholesterol aldehydes: The mechanisms of their formation and pahological roles in oxidative stress related-disorders2013
- Author(s)
  Noriyuki Miyoshi, Susumu Tomono, Hiroshi Ohshima.
- Organizer
  3rd European Network for Oxysterol Research
- Place of Presentation
  Swansea, UK
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] 日本のヤマイモ類及びその植物ステロイド成分によるマウス大腸発がんの予防2012
- Author(s)
  Hiroshi Ohshima, Tomoki Nagasawa, Natsuko Asai, Noriyuki Miyoshi, Keiji Wakabayashi, Takuji Tanaka
- Organizer
  The 1st International Conference on Pharma-Food
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] 飲酒およびアセトアルデヒド曝露のバイオマーカーとしてのタンパク質中Nε-エチルリジンの有用性2012
- Author(s)
  Ryota Mabuchi, Noriyuki Miyoshi, Akira Yokoyama, Yoshihide Suwa, Kiyonari Kuriki, Toshinao Goda, Takashi Amagai, Hiroshi Ohshima
- Organizer
  日本環境変異原学会第41回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24300257
[Presentation] アセトアルデヒドを消去する食品及び食品成分の探索2010
- Author(s)
  鈴木啓子、三好規之、糠谷東雄、大島寛史
- Organizer
  第54回日本食品科学工学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21300280
[Presentation] 乳がんのリスクマーカーとしての尿中のカテコールエストロゲン-DNA付加体の分析2010
- Author(s)
  戸井口恭子、三好規之、東達也、糠谷東雄、高橋智、若林敬二、大島寛史
- Organizer
  第39回日本環境変異原学会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-21300280

1. OHSHIMA Hiroshi (80433209)

# of Collaborated Projects : 2results

# of Collaborated Products : 21results
2. MIYOSHI Noriyuki (70438191)

# of Collaborated Projects : 2results

# of Collaborated Products : 16results
3. GODA Toshinao (70195923)

# of Collaborated Projects : 2results

# of Collaborated Products : 2results
4. HIGASHI Tatsuya (90272963)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
5. TOMONO Susumu (60554011)

# of Collaborated Projects : 1results

# of Collaborated Products : 12results
6. NAKAMURA Yoshimasa

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
7. AMAGAI Takashi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
8. 藤原章雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

NUKAYA Haruo 糠谷 東雄

MIYOSHI Noriyuki 糠谷 春雄

糠谷 東男 ヌカヤ ハルオ

糠谷 東雄 ヌカヤ ハルオ

Research Projects

Research Products

Co-Researchers

Ozone-oxidized cholesterols as biomarkers for metabolic syndrome and life-style related diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidations of the mechanisms for the formation of cholesterol-ozonolysis products in inflamed tissues, their biological activities and involvement in disease development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comprehensive analysis of the lipophilic reactive carbonyls present in biological specimens by LC/ESI-MS/MS2015

Author(s)

Journal Title

Data Source

[Journal Article] Implications of cholesterol autoxidation products in the pathogenesis of inflammatory diseases.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytotoxic effects of secosterols and its derivatives on several cultured cells.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Occurrence of cytotoxic 9-oxononanoyl secosterol aldehydes in human low-density lipoprotein.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde : Implications for vascular and neurodegenerative diseases.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development and application of a method for identification of isothiocyanate-targeted molecules in colon cancer cells.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of Nε-ethyllysine in human plasma proteins by gas chromatography-negative ion chemical ionization/mass spectrometry as a biomarker for exposure to acetaldehyde and alcohol.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway.2011

Author(s)

Journal Title

Data Source

[Journal Article] Formation of cholesterol ozonolysis products in vitro and in vivo through a myeloperoxidase-dependent pathway2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] Denaturation of cellular proteins induced by secosterol aldehydes2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Global analysis of reactive carbonyls formed in neuronal PC-12 cells by exposed to amyloid-beta2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Identification of carcinogenic compounds formed by chronic ethanol feeding in feces of mice2013

Author(s)

Organizer

NUKAYA Haruo 糠谷東雄

MIYOSHI Noriyuki 糠谷春雄

糠谷東男ヌカヤハルオ

糠谷東雄ヌカヤハルオ