IWASAKA Toshizi 岩坂壽二

Researcher Number	00098120
Affiliation *help	2007 – 2011 : 関西医科大学, 医学部, 教授 2008 – 2009 : 関西医大, 医学部, 教授 2004 – 2005 : 関西医科大学, 医学部, 教授 1996 – 2002 : 関西医大, 医学部, 教授 1995 – 2002 : 関西医科大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine Except Principal Investigator Applied health science
Keywords	Principal Investigator 心筋梗塞 / 血管新生 / left ventricular remodeling / 左室再構築 / 心筋症 / ACE遺伝子多型 / レニン・アンジオテンシン系 / gene polymorphism / 死亡 / regenerative medicine … More Except Principal Investigator 脈波伝搬速度 / 有酸素運動 / 超音波組織ドップラ / 運動代謝 / 運動負荷 / 運動療法 / Tissue doppler echocardiography / 大動脈コンプライアンス / Exercise Therapy / 超音波組織ドラプ / 大動脈コンブライアンス / インピーダンス / aortic wall compliance / 末梢血流 Less

The role of oxidative stress and antioxidant dilemma in ischemic heart diseasePrincipal Investigator
- Principal Investigator
  
  IWASAKA Toshiji
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kansai Medical University
Evaluation of exercise therapy on peripheral hemodynamic changes and exercise tolerance in various health stages
- Principal Investigator
  
  KIMURA Yutaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kansai Medical University
Evaluation of aortic wall assessed by strain rate in exercise therapy and drug medication
- Principal Investigator
  
  KIMURA Yutaka
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kansai Medical University
Angiogeniseis and angiotensin IIPrincipal Investigator
- Principal Investigator
  
  IWASAKA Toshiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kansai Medical University
INFLUENCE OF BRAIN NATRIURETIC PEPTIDE DURING ACUTE PHASE ON LEFT VENTRICULAR REMODELING 1 YEAR AFTER MYOCARDIAL INFARCTIONPrincipal Investigator
- Principal Investigator
  
  IWASAKA Toshiji
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KANSAI MEDICAL UNIVERSITY
ASSOCIATION BETWEEN ANGIOTENSIN-CONVERTING ENZYME GENE POLYMORPHISM AND LEFT VENTRICULAR REMODELING AFTER MYOCARDIAL INFARCTIONPrincipal Investigator
- Principal Investigator
  
  IWASAKA Toshiji
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KANSAI MEDICAL UNIVERSITY

All 2011 2010 2008

All Journal Article Presentation

[Journal Article] Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction2011
- Author(s)
  嶋津孝幸, 大谷肇, 吉岡慶, 藤田昌哲, 岡崎徹, 岩坂壽二
- Journal Title
  
  American Journal of Physiology Heart Circulatory Physiology
  
  Volume : 301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590847
[Journal Article] Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart2011
- Author(s)
  Okazaki T, Otani H, Shimazu T, Yoshioka K, Fujita M, Katano T, Ito S, Iwasaka T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume : 50 Pages : 534-544
- Data Source
  KAKENHI-PROJECT-20590847
[Journal Article] Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice2011
- Author(s)
  Jo H, Otani H, Jo F, Shimazu T, Okazaki T, Yoshioka K, Fujita M, Kosaki A, Iwasaka T
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume : 38 Pages : 485-493
- Data Source
  KAKENHI-PROJECT-20590847
[Journal Article] Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart.2011
- Author(s)
  Okazaki T, Otani H, Shimazu T, Yoshioka K, Fujita M, Katano T, Ito S, Iwasaka T.
- Journal Title
  
  J Mol Cell Cardiol. 50
  
  Pages : 534-544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590847
[Journal Article] New index of regional arterial stiffness assessed by tissue Doppler imaging2008
- Author(s)
  Mio Haiden, Yutaka Kimura, Yoko Miyasaka, Yasuko Aota, Kinuko Dote, Atsuaki Takada, Toshiji Iwasaka
- Journal Title
  
  Acta Cardiol 63
  
  Pages : 603-608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500621
[Journal Article] N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.2008
- Author(s)
  Matsuhisa S, Otani H, Okazaki T, Yamashita K, Akita Y, Sato D, Moriguchi A, Iwasaka T.
- Journal Title
  
  Antioxid Redox Signal. 10
  
  Pages : 1999-2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Sepiapterin inhibits adaptive left ventricular hypertrophy but prevents dilatory remodeling induced by pressure overload in rats2011
- Author(s)
  吉岡慶, 大谷肇, 嶋津孝幸, 藤田昌哲, 岡崎徹, 佐藤大祐, 岩坂壽二
- Organizer
  60th Annual Scientific Session of American College of Cardiology
- Place of Presentation
  アメリカ,ニューオリンズ
- Year and Date
  2011-04-03
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice2010
- Author(s)
  Joh H, Otani H, Okazaki T, Shimazu T, Fujita M, Yoshioka K, Satoh D, Iwasaka T
- Organizer
  第74回日本循環器学会学術集会
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Dual role of inducible nitric oxide synthase in left ventricular injury and protection after myocardial infarction in mice.2010
- Author(s)
  Shimazu T, Otani H, Fujita M, Yoshioka K, Okazaki T, Iwasaka T.
- Organizer
  American Heart Association Scientific Sessions 2010.
- Place of Presentation
  米国シカゴ
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Inhibition of iNOS uncoupling by tetrahydrobiopterin confers cardioprotection through protein S-nitrosylation2008
- Author(s)
  Okazaki T, Otani H, Yamashita K, Jo H, Yoshioka K, Moriguchi A, Iwasaka T.
- Organizer
  American Heart Association Scientific Sessions 2008
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Inhibition of contractile activity during ischemic postconditioning enhances cardioprotection through RISK-dependent restoration of sarcolemmal dystrophin.2008
- Author(s)
  Moriguchi A, Otani H, Yamashita K, Yoshioka K, Okazaki T, Iwasaka T.
- Organizer
  American Heart Association Scientific Sessions 2008.
- Place of Presentation
  米国ニューオーリンズ
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-20590847
[Presentation] Inhibition of iNOS uncoupling by tetrahydrobiopterin confers cardioprotection through protein S-nitrosylation.2008
- Author(s)
  Okazaki T, Otani H, Yamashita K, Jo H, Yoshioka K, Moriguchi A, Iwasaka T.
- Organizer
  American Heart Association Scientific Sessions 2008.
- Place of Presentation
  米国ニューオーリンズ
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-20590847

1. IHARADA Yoshizi (00351502)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
2. KOSAKI Atushi (40330188)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
3. KIMURA Yutaka (60298859)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
4. YAMAMOTO Satoshi (10298888)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
5. MATSUBARA Hiroaki (10239072)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
6. TSUJI Hisako (60201638)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. OTANI Hajime (60168979)

# of Collaborated Projects : 1results

# of Collaborated Products : 11results
8. HAIDEN Mio (80351534)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

IWASAKA Toshizi 岩坂 壽二

Research Projects

Research Products

Co-Researchers

The role of oxidative stress and antioxidant dilemma in ischemic heart diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of exercise therapy on peripheral hemodynamic changes and exercise tolerance in various health stages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of aortic wall assessed by strain rate in exercise therapy and drug medication

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Angiogeniseis and angiotensin IIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

INFLUENCE OF BRAIN NATRIURETIC PEPTIDE DURING ACUTE PHASE ON LEFT VENTRICULAR REMODELING 1 YEAR AFTER MYOCARDIAL INFARCTIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ASSOCIATION BETWEEN ANGIOTENSIN-CONVERTING ENZYME GENE POLYMORPHISM AND LEFT VENTRICULAR REMODELING AFTER MYOCARDIAL INFARCTIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction2011

Author(s)

Journal Title

Data Source

[Journal Article] Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart2011

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice2011

Author(s)

Journal Title

Data Source

[Journal Article] Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart.2011

Author(s)

Journal Title

Data Source

[Journal Article] New index of regional arterial stiffness assessed by tissue Doppler imaging2008

Author(s)

Journal Title

Data Source

[Journal Article] N-acetylcysteine abolishes the protective effect of losartan against left ventricular remodeling in cardiomyopathy hamster.2008

Author(s)

Journal Title

Data Source

[Presentation] Sepiapterin inhibits adaptive left ventricular hypertrophy but prevents dilatory remodeling induced by pressure overload in rats2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Inhibition of nitric oxide synthase uncoupling by sepiapterin improves left ventricular function in streptozotocin-induced diabetic mice2010

Author(s)

Organizer

Year and Date

Data Source

[Presentation] Dual role of inducible nitric oxide synthase in left ventricular injury and protection after myocardial infarction in mice.2010

Author(s)

Organizer

Place of Presentation

Year and Date

IWASAKA Toshizi 岩坂壽二