Kubo Miyoko 久保美代子

… Alternative Names

久保美代子クボミヨコ

KUBO Miyoko 久保美代子

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Researcher Number	00098609
Other IDs
Affiliation (Current)	2025: 岡山大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 岡山大学, 医学部, 客員研究員 2012 – 2013: 岡山大学, 医学部, 客員研究員 2008 – 2011: Kawasaki Medical School, 医学部, 講師 2001 – 2006: 川崎医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Plastic surgery / Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery
Keywords	Principal Investigator 再上皮化 / フィブロネクチン / 培養表皮 / 変性コラーゲン / 再生医療 / 難治性潰瘍 / β3インテグリン遺伝子導入ヒト表皮角化細胞 / α5β1 / αvβ3 / laminin-1 … More / re-epithelialization / pressure ulcers / chronic wounds / 細胞外基質 / ラミニン / 褥瘡 / 慢性創傷 / 再生医学 / 遺伝子導入ヒト表皮角化細胞 / αvβ３インテグリン / 細胞治療 / 再上皮化促進 / β3インテグリン / α5インテグリン / 正常ヒト表皮角化細胞 / フィブリンゲル / β3遺伝子導入ヒト表皮角化細胞 / fibronection / burns / αvβ6 / ラミニン-1 / 熱傷 / 再上皮化遅延 / 褥層 / cultured epithelium / cell migration / cell growth / cell adhesion / gene transfer / human keratinocytes / ゼラチンマイクロビーズ / 細胞移動能 / 細胞接着能 / 細胞移動 / 細胞増殖 / 細胞接着 / 遺伝子導入 / ヒトケラチノサイト / acute wound model / fibronectin / avβ6 integrin / α5 β1 integrin / 表皮遊走 / インテグリン / 慢性皮膚潰瘍 / 皮膚創傷治療 / ラット急性創傷モデル / αvβ6インテグリン / α5β1インテグリン / フィブリン / 動物実験 / 移植・再生医療 Less

難治性潰瘍での変性コラーゲンの局在証明、再上皮化遅延の病態解明とその治療法開発Principal Investigator
- Principal Investigator
  
  久保美代子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Okayama University
β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療Principal Investigator
- Principal Investigator
  
  久保美代子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Okayama University
The establishment of regenerative medicine for promoting re-epithelialization of chronic wounds -based on re-epithelialization mechanisms-Principal Investigator
- Principal Investigator
  
  KUBO Miyoko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Okayama University
  Kawasaki Medical School
Verification for the effectiveness of β3 integrin-recombinant cultured epithelium by animal experimentsPrincipal Investigator
- Principal Investigator
  
  KUBO Miyoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kawasaki Medical School
Clarification of mechanisms for delayed re-epithelialization of chronic wounds -to establish treatment based on wound healing theory-Principal Investigator
- Principal Investigator
  
  KUBO Miyoko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kawasaki Medical School
Development of Cultured Epithelium Using β3 Integrin Subunit cDNA-Transduced Human Keratinocytes - To Improve the Take Rate -Principal Investigator
- Principal Investigator
  
  KUBO Miyoko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Kawasaki Medical School
Alteration of Integrin Expression in Migrating Epidermal Cells and Analysis of Extracellular Matrix Proteins in the Dermis with Chronic WoundsPrincipal Investigator
- Principal Investigator
  
  KUBO Miyoko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Kawasaki Medical School

All 2023 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩第2版2005
- Author(s)
  久保美代子, 森口隆彦
- Publisher
  克誠堂出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390543
[Book] 形成外科ADVANCEシリーズI-3 創傷の治療最近の進歩第2版2005
- Author(s)
  久保美代子, 森口隆彦
- Total Pages
  9
- Publisher
  克誠堂出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩改訂第2版2005
- Author(s)
  久保美代子, 森口隆彦
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-15390543
[Journal Article] Tranilast inhibits the cell growth of normal human keratinocytes in vitro.2012
- Author(s)
  Miyoko Mubo, Ying Zhao, Takahiko Moriguchi
- Journal Title
  
  Arch Dermatol Res
  
  Volume: 304 Issue: 9 Pages: 745-753
- DOI
  10.1007/s00403-012-1291-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592661
[Journal Article] フィブラスト^[○!R]スプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011
- Author(s)
  久保美代子,森口隆彦
- Journal Title
  
  日本皮膚科学会雑誌 (in press)
- Data Source
  KAKENHI-PROJECT-20592112
[Journal Article] フィブラストスプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011
- Author(s)
  久保美代子,森口隆彦
- Journal Title
  
  日本皮膚科学会雑誌
  
  Volume: 121 Pages: 1607-1620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592661
[Journal Article] フィブラスト^[○!R]スプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011
- Author(s)
  久保美代子, 森口隆彦
- Journal Title
  
  日本皮膚科学会雑誌
  
  Volume: 121巻(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592112
[Journal Article] フィブラストスプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト，正常ヒト線維芽細胞に対する細胞毒性について2011
- Author(s)
  久保美代子，森口隆彦
- Journal Title
  
  日本皮膚科学会雑誌
  
  Volume: 121 Pages: 1607-1620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592661
[Journal Article] Transduction of β3 integrin subunit cDNA confers on human keratinocytes the ability to adhere to gelatin.2007
- Author(s)
  Miyoko Kubo
- Journal Title
  
  Arch Dermatol Res 299・1
  
  Pages: 13-24
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Transduction of β 3 integrin subunit cDNA confers on human keratinocytes the ability to adhere to gelatin.2007
- Author(s)
  Miyoko Kubo
- Journal Title
  
  Arch Dermatol Res 299・1
  
  Pages: 13-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Ying Zhao and Takahiko Moriguchi : Transduction of β3 Integrin Subunit cDNA Confers on Human Keratinocytes the Ability to Adhere to Gelatin.2007
- Author(s)
  Miyoko Kubo, Richard A.F.Clark, Anne B.Katz, Lorne B.Taichman, Zaishun Jin
- Journal Title
  
  Arch Dermatol Res 299-1
  
  Pages: 13-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] 肥厚性癒痕,ケロイドでの血管新生2006
- Author(s)
  久保美代子
- Journal Title
  
  医学のあゆみ 219・7
  
  Pages: 513-516
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] ケラチノサイトの細胞増殖に与えるbFGFの効果について2006
- Author(s)
  久保美代子
- Journal Title
  
  皮膚の科学 5・増6
  
  Pages: 16-20
- NAID
  130004547204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Angiogesis in Hypertrophic Scars and Keloids.2006
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Journal Title
  
  Journal of Clinical and Experimental Medicine (IGAKU NO AYUMI) 219-7
  
  Pages: 513-516
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Effects of bFGF on the Cell Growth of Keratinocytes.2006
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Journal Title
  
  Skin Research 5-Suppl.6
  
  Pages: 16-20
- NAID
  130004547204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] 肥厚性瘢痕,ケロイドでの血管新生2006
- Author(s)
  久保美代子
- Journal Title
  
  医学のあゆみ 219・7
  
  Pages: 513-516
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Wound Healing of Chronic Wounds.2005
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Journal Title
  
  Plastic Surgery ADVANCE Series I-3, Treatment of Wounds : Recent Progress, 2nd Edition (T.Moriguchi ad.) (Kokuseido Press, Tokyo)
  
  Pages: 61-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390543
[Journal Article] Wound Healing in Chronic Wounds.2005
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Journal Title
  
  In : Plastic Surgery ADVANCE Series I・, Treatment of Wounds, Recent Progress, 2nd Edition, T. Moriguchi, ed., Kokuseido Press, Tokyo
  
  Pages: 61-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591882
[Journal Article] Gelatin Microspheres Crosslinked with γ-ray : Preparation, Sorption of Proteins, and Biodegradability.2004
- Author(s)
  Ken Terao, Tomotake Karino, Naotsugu Nagasawa, Fumio Yoshii, Miyoko Kubo, Toshiaki Dosashi
- Journal Title
  
  J Appl Polym Sci 91
  
  Pages: 3083-3087
- NAID
  120007053195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390543
[Presentation] β３インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発2023
- Author(s)
  久保美代子、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09847
[Presentation] 正常ならびにβ3インテグリン遺伝子導入ヒト表皮角化細胞のgelatin上での細胞増殖に違いについて2023
- Author(s)
  久保美代子、山本健一、木下理恵、阪口政清
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K09847
[Presentation] β３インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発2023
- Author(s)
  久保美代子、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
- Organizer
  第55回日本結合組織学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09079
[Presentation] The development of improved cultured epithelium using β3 cDNA-transduced keratinocytes to increase its take-rate.2011
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi, Natsumi Maehara, Ken Kataoka, Nam-ho HUH, Kiichi Inagawa
- Organizer
  17th International Society for Cellular Therapy Annual Meeting
- Place of Presentation
  Rotterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23592661
[Presentation] Beta3インテグリン・サブユニットcDNA導入ケラチノサイトを用いた培養表皮の開発-生着率向上に向けて-2011
- Author(s)
  久保美代子,森口隆彦,前原奈都美,片岡健,許南浩,稲川喜一
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京都
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] The development of improved cultured epithelium using β3 cDNA-transduced keratinocytes to increase its take-rate.2011
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi, Natsumi Maehara, Ken Kataoka, Nam-ho HUH, Kiichi Inagawa
- Organizer
  17th International Society for Cellular Therapy Annual Meeting
- Place of Presentation
  Rotterdam, Netherlands
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] The development of improved cultured epithelium usingβ3 cDNA-transduced keratinocytes to increase its take-rate2011
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi, Natsumi Maehara, Ken Kataoka, Nam-ho HUH, Kiichi Inagawa
- Organizer
  17th International Society for Cellular Therapy Annual Meeting
- Place of Presentation
  Rotterdam, Netherlands
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-23592661
[Presentation] Fibronectin distribution with pressure ulcers significantly decreased in the papillary dermis under the migrating epidermis compared with those of burns.2010
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi, Natsumi Maehara, Kiichi Inagawa
- Organizer
  20th European Tissue Repair Society Congress
- Place of Presentation
  Gent, Belgium
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] Fibronectin distribution with pressure ulcers significantly decreased in the papillary dermis under the migrating epidermis compared with those of burns.2010
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi, Natsumi Maehara, Kiichi Inagawa
- Organizer
  20^<th> European Tissue Repair Society Congress
- Place of Presentation
  Gent, Belgium
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] bFGFはI型コラーゲン上で培養した正常ヒトケラチノサイト, 正常ヒト線維芽細胞の細胞増殖を濃度依存性に促進する-フィブラストスブレー添付溶解液の細胞毒性による影響-2010
- Author(s)
  久保美代子, 森口隆彦
- Organizer
  第59回日本形成外科学会中国・四国支部学術集会
- Place of Presentation
  広島市民病院(広島市)
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] bFGFはI型コラーゲン上で培養した正常ヒトケラチノサイト, 正常ヒト線維芽細胞の細胞増殖を濃度依存性に促進する-フィブラストスプレー添付溶解液の細胞毒性による影響-2010
- Author(s)
  久保美代子,森口隆彦
- Organizer
  第59回日本形成外科学会中国・四国支部学術集会
- Place of Presentation
  広島市
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] bFGFのケラチノサイト,線維芽細胞への細胞増殖促進効果とフィブラスト^[○!R]スプレー添付溶解液の細胞毒性2010
- Author(s)
  久保美代子,森口隆彦,稲川喜一
- Organizer
  第2回日本創傷外科学会
- Place of Presentation
  神戸市
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] 褥瘡では熱傷に比べて真皮内の種々の部位でフィブロネクチン分布が減少する2009
- Author(s)
  久保美代子,森口隆彦
- Organizer
  第1回日本創傷外科学会
- Place of Presentation
  東京都
- Year and Date
  2009-01-17
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] Basic fibroblast growth factor increases cell growth of normal human keratinocytes and fibroblasts in extracellular matrix-and dose-dependent manners.2008
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Organizer
  The Third World Union of Wound Healing Societies' Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] Basic fibroblast growth factor increases cell growth of normal human keratinocytes and fibroblasts in extracellular matrix- and dose-dependent manners.2008
- Author(s)
  Miyoko Kubo, Takahiko Moriguchi
- Organizer
  The Third World Union of Wound Healing Societies' Meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-20592112
[Presentation] ヒトケラチノサイト, 線維芽細胞のin vitroでの細胞増殖に対するbFGFの効果-フィブラストスプレーとbFGF 原末との比較-2008
- Author(s)
  久保美代子, 森口隆彦
- Organizer
  第6回bFGF創傷治癒研究会
- Place of Presentation
  東京都
- Year and Date
  2008-10-24
- Data Source
  KAKENHI-PROJECT-20592112

1. MORIGUCHI Takahiko (10111816)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. 山本健一 (00711798)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 土橋敏明 (30155626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 牧野英一 (90314674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 木下理恵 (40518297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 米澤朋子 (30304299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大橋俊孝 (50194262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 白井朋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kubo Miyoko 久保 美代子

久保 美代子 クボ ミヨコ

KUBO Miyoko 久保 美代子

Research Projects

Research Products

Co-Researchers

難治性潰瘍での変性コラーゲンの局在証明、再上皮化遅延の病態解明とその治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The establishment of regenerative medicine for promoting re-epithelialization of chronic wounds -based on re-epithelialization mechanisms-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Verification for the effectiveness of β3 integrin-recombinant cultured epithelium by animal experimentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of mechanisms for delayed re-epithelialization of chronic wounds -to establish treatment based on wound healing theory-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Cultured Epithelium Using β3 Integrin Subunit cDNA-Transduced Human Keratinocytes - To Improve the Take Rate -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Alteration of Integrin Expression in Migrating Epidermal Cells and Analysis of Extracellular Matrix Proteins in the Dermis with Chronic WoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩 第2版2005

Author(s)

Publisher

Description

Data Source

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療 最近の進歩 第2版2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩 改訂第2版2005

Author(s)

Publisher

Data Source

[Journal Article] Tranilast inhibits the cell growth of normal human keratinocytes in vitro.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] フィブラスト^[○!R]スプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011

Author(s)

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[Journal Article] フィブラストスプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011

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[Journal Article] フィブラスト^[○!R]スプレー添付溶解液および塩化ベンザルコニウムのI型コラーゲン上で培養した正常ヒトケラチノサイト,正常ヒト線維芽細胞に対する細胞毒性について2011

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Kubo Miyoko 久保美代子

久保美代子クボミヨコ

KUBO Miyoko 久保美代子

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩第2版2005

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療最近の進歩第2版2005

[Book] 形成外科ADVANCEシリーズI-3 創傷の治療:最近の進歩改訂第2版2005