IWAO Masatomo 岩尾正倫

Researcher Number	00100892
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2016: 長崎大学, 工学研究科, 教授 2013: 長崎大学, 工学部, 教授 2011 – 2013: 長崎大学, 工学(系)研究科(研究院), 教授 2010 – 2011: 長崎大学, 大学院・工学研究科, 教授 2006 – 2010: 長崎大学, 工学部, 教授 2002 – 2004: 長崎大学, 工学部, 教授 1997 – 2000: 長崎大学, 工学部, 教授
Review Section/Research Field	Principal Investigator Bioorganic chemistry / Living organism molecular science / Drug development chemistry Except Principal Investigator Applied pharmacology
Keywords	Principal Investigator ラメラリン / 海洋天然物 / 抗がん剤 / 構造活性相関 / ラメラリンN / ピロロイミノキノン / 海洋アルカロイド / lamellarin G trimethyl ether / lamellarin D / lamellarin L … More / lamellarin N / permethyl storniamide A / ningalin B / 化学合成 / トポイソメラーゼI / プロテインキナーゼ / 選択的阻害剤 / ドッキングシミュレーション / 活性発現分子機構 / 軸不斉化合物 / 光学分割 / キナーゼ阻害剤 / がん / 神経変成疾患 / アルツハイマー病 / トポイソメラーゼI阻害 / サイクリン依存性キナーゼ阻害 / 分子機構 / 軸不斉 / サイクリン依存性キナーゼ / HPLC / トポイソメラーゼ1 / 非小細胞肺がん / EGFR-TKI / L858R/T790M変異 / L858R/T790M/C797S変異 / ゲフィチニブ耐性 / オシメルチニブ耐性 / アザラメラリン / L858R/T790M / L858R/T790M/C797S / ゲフィチニブ / オシメルチニブ / アザアメラリン / 薬剤耐性変異 / アファチニブ / ピロロイキノミノン / マカルバミン / ベイユタミン / 抗腫瘍性 / インドール / リチオ化 / MARINE NATURAL PRODUCTS / PYRROLOIMINOQUINONE / MAKALUVAMINES / VEIUTAMINE / ANTITUMOR COMPOUNDS / INDOLE / LITHIATION / 抗がん性物質 / トポイソメラーゼ阻害 / トポイソメラーゼ / リチオ化反応 / marine natural products / pyrroloiminoquinone / anticancer agent / topoisomerase inhibition / 多剤耐性がん / 海洋産ピロールアルカロイド / 多剤耐性克服作用 / ピロールアルカロイド / ラメラリンD / ラメラリンL / 多剤耐性ガン / ニンガリン / ストルニアミド / lamellarin / stroniamide / ningalin / multidrug-resistant cancer / marine pyrrole alkaloids / 多剤耐性(MDR) / トポイソメラーゼI阻害剤 / 薬物設計 / 分子設計 / 合成 / lamellarins / multidrug resistat(MDR) / antitumor agent / topoisomerase I inhibitor / drug design / chemical synthesis … More Except Principal Investigator 抗HTLV-1薬 / 分子標的治療薬 / 成人T細胞白血病 / 新規抗がん剤 / 抗ウィルス薬 Less

Development of EGFR-Tyrosine Kinase Inhibitors Effective for Non-Small Cell Lung Cancer Resistant to GefitinibPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagasaki University
Possibility of a new synthetics from lamellarins: anti-leukemic and integrase-inhibitory effects against HTLV-1-related leukemia cells.
- Principal Investigator
  
  HASEGAWA Hiroo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Nagasaki University
Elucidation and Control of the Molecular Mechanism of Action of the Multifunctional Antitumor Agents LamellarinsPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Nagasaki University
Design and Synthesis of New Antitumor Agents Using Marine Natural Product Lamellarin as A Structural MotifPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Nagasaki University
Chemical Synthesis of marine pyrrole alkaloids effective against multidrug-resistant cancersPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Nagasaki University
Creation of novel antitumor agents having DNA topoisomerase inhibition activityPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Nagasaki university
STUDIES ON THE SYNTHESIS OF ANTITUMOR PYRROLOIMINOQUINONE MARINE ALKALOIDSPrincipal Investigator
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  NAGASAKI UNIVERSITY

[Journal Article] Synthesis of Lamellarins via Regioselective Assembly of 1,2-Diarylated [1]Benzopyrano[3,4-b]pyrrol-4(3H)-one Core2017
- Author(s)
  Tsutomu Fukuda, Takatoshi Katae, Issei Harada, Masatomo Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 95 Pages: 950-971
- DOI
  10.3987/com-16-s(s)63
- NAID
  120006987527
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293028, KAKENHI-PROJECT-15K01802
[Journal Article] Regioselective Synthesis of 2,4-Differentially Arylated Pyrroles and Its Application to the Synthesis of Lamellarins2016
- Author(s)
  Tsutomu Fukuda, Mizuho Anzai, Masatomo Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 93
- DOI
  10.3987/com-15-s(t)49
- NAID
  120006987526
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K01802, KAKENHI-PROJECT-26293028
[Journal Article] A Synthesis of Lamellarins via Regioselective Assembly of 1,2,3-Differentially Substituted 5,6-Dihydropyrrolo[2,1-a]isoquinoline Core2015
- Author(s)
  T. Fukuda, D. Sato, M. Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 91 Pages: 782-794
- DOI
  10.3987/com-15-13188
- NAID
  120006987123
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293028
[Journal Article] Synthesis of Non-Steroidal Estrogen Receptor Antagonists R1128 A, B, C, and D via an Oxazoline-Promoted Iterative ortho-Lithiation Strategy2012
- Author(s)
  T.Fukuda, K.Fukushima, S.Sanai, M.Iwao
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 85 Issue: 1 Pages: 133-135
- DOI
  10.1246/bcsj.20110243
- NAID
  10030217983
- ISSN
  0009-2673, 1348-0634
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135, KAKENHI-PROJECT-22510235
[Journal Article] Synthesis of non-steroidal estrogen receptor antagonists R1128 A, B, C, and D via an oxazoline-promoted iterative ortho-lithiation strategy2012
- Author(s)
  T. Fukuda, K. Fukushima, S. Sanai, and M. Iwao
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: Vol.85, No.1 Pages: 133-135
- NAID
  10030217983
- URL
  http://hdl.handle.net/10069/27467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Infection of XC cells by MLVs and ebola virus is endosome-dependent but acidification-independent2011
- Author(s)
  神山陽香, 岩尾正倫, 久保嘉直, 他
- Journal Title
  
  PLoS ONE
  
  Volume: 6
- DOI
  10.1371/journal.pone.0026180
- NAID
  120006985272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07637, KAKENHI-PROJECT-20310135, KAKENHI-PROJECT-22590416
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : An overview2011
- Author(s)
  T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Heterocycles 83(3)
  
  Pages: 491-529
- NAID
  120006984843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : an overview2011
- Author(s)
  T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  Heterocycles
  
  Volume: Vol.83, No.3 Pages: 491-529
- NAID
  120006984843
- URL
  http://hdl.handle.net/10069/24666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis, structure. activity relationships, and mechanism of action of anti-HIV-1 lamellarinα20-sulfate analogues2011
- Author(s)
  H. Kamiyama, Y. Kubo, H. Sato, N. Yamamoto, T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: Vol.19, No.24 Pages: 7541-7550
- NAID
  120006985218
- URL
  http://hdl.handle.net/10069/26755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis, structure-activity relationships, and mechanism of action of anti-HIV-1 lamellarin α 20-sulfate analogues2011
- Author(s)
  神山陽香, 岩尾正倫, 久保嘉直, 他
- Journal Title
  
  Bioorg.Med.Chem.
  
  Volume: 19 Pages: 7541-50
- DOI
  10.1016/j.bmc.2011.10.030
- NAID
  120006985218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07637, KAKENHI-PROJECT-20310135, KAKENHI-PROJECT-22510235, KAKENHI-PROJECT-22590416
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : an overview2011
- Author(s)
  T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 83 Pages: 491-529
- NAID
  120006984843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Directed Lithiation of N-Benzenesulfonyl-3-bromopyrrole. Electrophile-Controlled Regioselective Functionalization via Dynamic Equilibrium between C-2 and C-5 Lithio Species2010
- Author(s)
  T.Fukuda, T.Ohta, E.Sudo, M.Iwao
- Journal Title
  
  Organic Letters
  
  Volume: 12 Pages: 2734-2737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Divergent synthesis of lamellarin α13-sulfate, 20-sulfate, and 13, 20-disulfate2010
- Author(s)
  T.Fukuda, T.Ohta, S.Saeki, M.Iwao
- Journal Title
  
  Heterocycles 80(2)
  
  Pages: 841-846
- NAID
  120006984657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Divergent synthesis of lamellarinα13-sulfate, 20-sulfate, and 13, 20-disulfate2010
- Author(s)
  T. Fukuda, T. Ohta, S. Saeki, and M. Iwao
- Journal Title
  
  Heterocycles
  
  Volume: Vol.80, No.2 Pages: 841-846
- NAID
  120006984657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Directed lithiation of N-benzenesulfonyl-3-bromopyrrole. Electrophile-controlled regioselective functionalization via dynamic equilibrium between C-2 and C-5 lithio species2010
- Author(s)
  T. Fukuda, T. Ohta, E. Sudo, and M. Iwao
- Journal Title
  
  Organic Letters
  
  Volume: Vol.12, No.12 Pages: 2734-2737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S. Hirao, Y. Yoshinaga, M. Iwao, and F. Ishibashi
- Journal Title
  
  Tetrahedron Letters
  
  Volume: Vol.51, No.3 Pages: 533-536
- NAID
  120006984589
- URL
  http://hdl.handle.net/10069/23109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S.Hirao, Y.Yoshinaga, M.Iwao, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 51
  
  Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S.Hirao, Y.Yoshinaga, M.Iwao, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 51(3)
  
  Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Divergent synthesis of lamellarin α 13-sulfate, 20-sulfate, and 13, 20-disulfate2010
- Author(s)
  T.Fukuda, T.Ohta, S.Saeki, M.Iwao
- Journal Title
  
  Heterocycles 80
  
  Pages: 841-846
- NAID
  120006984657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic approach to telomerase inhibitor dictyodendrin B : synthesis of the pyrrolo[ 2, 3-c] carbazole core2009
- Author(s)
  S. Hirao, Y. Sugiyama, M. Iwao, and F. Ishibashi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: Vol.73, No.8 Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T. Ohta, T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: Vol.74, No.21 Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T.Ohta, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Journal of Organic Chemistry 74(21)
  
  Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic approach to telomerase inhibitor dictyodendrin B : synthesis of the pyrrolo[2,3-c]carbazole core2009
- Author(s)
  S.Hirao, Y.Sugiyama, M.Iwao, F.Ishibashi
- Journal Title
  
  Bioscience Biotechnology, and Biochemistry 73
  
  Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A general method for the synthesis of N-unsubstituted 3, 4-diarylpyrrole-2, 5-dicarboxylates2009
- Author(s)
  T. Fukuda, Y. Hayashida, and M. Iwao
- Journal Title
  
  Heterocycles
  
  Volume: Vol.77, No.2 Pages: 1105-1122
- NAID
  120006983334
- URL
  http://hdl.handle.net/10069/20926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A GENERAL METHOD FOR THE SYNTHESIS OF N-UNSUBSTITUTED 3, 4-DIARYLPYRROLE-2, 5-DICARBOXYLATES2009
- Author(s)
  T. Fukuda, Y. Hayashida, M. Iwao
- Journal Title
  
  Heterocycles 77
  
  Pages: 1105-1122
- NAID
  120006983334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T.Ohta, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  The Journal of Organic Chemistry 74
  
  Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] SYNTHESIS OF 1', 2', 3', 4', 5' -PENT AMETHYL-3, 4-DIPHENYLAZAFERROCENE AND ITS ENANTIOSELECTIVE C-2 FUNCTIONALIZATION VIA (-)-SPARTEINE-MEDIATED LITHIATION2008
- Author(s)
  T. Fukuda, Y. Koga, M. Iwao
- Journal Title
  
  Heterocycles 76
  
  Pages: 1237-1248
- NAID
  120006982301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Palladium-catalyzed cross-coupling of N-benzenesulfonyl-3,4-dibromopyrrole and its application to the total syntheses of lamellarins O,P,Q,and R2008
- Author(s)
  T. Fukuda, E. Sudo, K. Shimokawa, M. Iwao
- Journal Title
  
  Tetrahedron 64
  
  Pages: 328-338
- NAID
  120006981677
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Palladium-catalyzed cross-coupling of N-benzenesulfony1-3, 4-dibromopyrrole and its application to the total syntheses of lamellarins O, P, Q, and R2008
- Author(s)
  T., Fukuda, E., Sudo, K., Shimokawa, M., Iwao
- Journal Title
  
  Tetrahedron 64-2
  
  Pages: 328-338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D. Baunbak, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Rucirawat, F. Ishibashi, M. Iwao, and L. Meijer
- Journal Title
  
  Marine Drugs
  
  Volume: Vol.6, No.4 Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Anticancer Alkaloid Lamellarins Inhibit Protein Kinases2008
- Author(s)
  D. Baunbffik, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Rucirawat, F. Ishibashi, M. Iwao, L. Meiier
- Journal Title
  
  Marine Drugs 6
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D.Baunbaeck, N.Trinkler, Y.Ferandin, O.Lozach, P.Ploypradith, S.Ruchirawat, F.Ishibashi, M.Iwao, L.Meijer
- Journal Title
  
  Marine Drugs 6(4)
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Palladium-catalyzed cross-coupling of N-benzenesulfonyl-3,4-dibromopyrrole and its application to the total syntheses of lamellarins O,P,Q,and R2008
- Author(s)
  T.Fukuda, E.Sudo, K.Shimokawa, M.Iwao
- Journal Title
  
  Tetrahedron 64
  
  Pages: 328-338
- NAID
  120006981677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Asymmetric synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins from (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline2007
- Author(s)
  K.Uchida, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedrom 63
  
  Pages: 7178-7186
- NAID
  120006982362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] SYNTHESIS OF BOTH ENANTIOMERS OF PROTOBERBERINES VIA LATERALLY LITHIATED (S)-4-ISOPROPYL-2-(o-TOLYL)OXAZOLINES2007
- Author(s)
  T.Fukuda, M.Iwao
- Journal Title
  
  Heterocycles 74
  
  Pages: 701-720
- NAID
  120006981669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] SYNTHESIS OF BOTH ENANTIOMERS OF PROTOBERBERINES VIA LATERALLY LITHIATED (S)-4-ISOPROPYL-2(ο-TOLYL)OXAZOLINES2007
- Author(s)
  T. Fukuda, M. Iwao
- Journal Title
  
  Heterocycles 74
  
  Pages: 701-720
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Asymmetric synthesis of 3-substituted 8-hydroxy-3, 4-dihydroisocoumarins from(S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline2007
- Author(s)
  K., Uchida, T., Fukuda, M., Iwao
- Journal Title
  
  Tetrahedron 63-30
  
  Pages: 7178-7186
- NAID
  120006982362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Asymmetric synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins from (S)-4-isopropyl-2-(2-methoxy-6-methylphenyl)oxazoline2007
- Author(s)
  K. Uchida, T. Fukuda, M. Iwao
- Journal Title
  
  Tetrahedron 63
  
  Pages: 7178-7186
- NAID
  120006982362
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] SYNTHESIS OF BOTH ENANTIOMERS OF PROTOBERBERINES VIA LATERALLY LITHIATED(S)-4-ISOPROPYL-2-(o-TOLYL)OXAZOLINES2007
- Author(s)
  T., Fukuda, M., Iwao
- Journal Title
  
  Heterocycles 74-1
  
  Pages: 701-720
- NAID
  120006981669
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] The first total synthesis of lamellarin a 20-sulfate, a selective inhibitor of HIV-1 integrase2006
- Author(s)
  T., Yamaguchi, T., Fukuda, F., Ishibashi, M., Iwao
- Journal Title
  
  Tetrahedron Letters 47-22
  
  Pages: 3755-3757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Total synthesis of lamellarins D, L, and N2006
- Author(s)
  N., Fujikawa, T., Ohta, T., Yamaguchi, T., Fukuda, F., Ishibashi, M., Iwao
- Journal Title
  
  Tetrahedron 62-4
  
  Pages: 594-604
- NAID
  120006982364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Total synthesis of lamellarins D,L,and N2006
- Author(s)
  N. Fujikawa, T. Ohta, T. Yamaguchi, T. Fukuda, F. Ishibashi, M. Iwao
- Journal Title
  
  Tetrahedron 62・4
  
  Pages: 594-604
- NAID
  120006982364
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] The first total synthesis of lamellarin α20-sulfate, a selective inhibitor of HIV-1 integrase2006
- Author(s)
  T.Yamaguchi, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Tetrahedron Letters 47・22
  
  Pages: 3755-3757
- NAID
  120006982363
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Total synthesis of lamellarins D, L, and N2006
- Author(s)
  N.Fujikawa, T.Ohta, T.Yamaguchi, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Tetrahedron 62・4
  
  Pages: 594-604
- NAID
  120006982364
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] The first total synthesis of lamellarin α 20-sulfate,a selective inhibitor of HIV-1 integrase2006
- Author(s)
  T. Yamaguchi, T. Fukuda, F. Ishibashi, M. Iwao
- Journal Title
  
  Tetrahedron Letters 47・22
  
  Pages: 3755-3757
- NAID
  120006982363
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18510188
[Journal Article] Asymmetric synthesis of 3-substitutes 3,4-dihydroidocoumarins via stereoselective addition of laterally lithiated chiral 2-(ο-tolyl)oxazolines to aldehydes followed by diastereomer-selective lactonization2005
- Author(s)
  Y.Kurosaki, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron 61・13
  
  Pages: 3289-3303
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Asymmetric synthesis of 3-substituted 3,4-dihydroisocoumarins via stereoselective addition of laterally lithiated chiral 2-(o-tolyl)oxazolines to aldehydes followed by diastereomer-selective lactonization2005
- Author(s)
  Y.Kurosaki, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron 61-13
  
  Pages: 3289-3303
- NAID
  120006982350
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Asymmetric synthesis of 3-substituted 3,4-dihydroisocoumarins via stereoselective addition of laterally lithiated chiral 2-(o-tolyl)oxazolines to aldehydes followed by diastereomer-selective lactonization2005
- Author(s)
  Y.Kurosaki, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron 61・13
  
  Pages: 3289-3303
- NAID
  120006982350
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins via successive lateral and ortho-lithiations of 4,4-dimethyl-2-(o-tolyl)oxazoline2004
- Author(s)
  N.Tahara, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron Letters 45-26
  
  Pages: 5117-5120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Synthesis of 3-substituted 8-hydroxy-3,4-dihyroisocoumarind via successive lateral and ortho-lithiations of 4,4-dimethyl-2-(ο-tolyl)oxazoline2004
- Author(s)
  N.Tahara, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron Letters 45・26
  
  Pages: 5117-5120
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Synthesis of 3-substituted 8-hydroxy-3,4-dihydroisocoumarins via successive lateral and ortho-lithiations of 4,4-dimethyl-2-(o-tolyl)oxazoline2004
- Author(s)
  N.Tahara, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron Letters 45・26
  
  Pages: 5117-5120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Short and flexible route to 3,4-diarylpyrrole marine alkaloids : syntheses of permethyl storniamide A, ningalin B, and lamellarin G trimethyl ether2003
- Author(s)
  M.Iwao, T.Takeuchi, N.Fujikawa, T.Fukuda, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 44・24
  
  Pages: 4443-4446
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Enantioselective synthesis of planar chiral azaferrocenes via chiral ligand-mediated ring- and lateral lithiations2003
- Author(s)
  T.Fukuda, K.Imazato, M.Iwao
- Journal Title
  
  Tetrahedron Letters 44・40
  
  Pages: 7503-7506
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Short and flexible route to 3,4-diarylpyrrole marine alkaloids : syntheses of permethyl storniamide A, ningalin B, and lamellarin G trimethyl ether2003
- Author(s)
  M.Iwao, T.Takeuchi, N.Fujikawa, T.Fukuda, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 44-24
  
  Pages: 4443-4446
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Enantioselective synthesis of planar chiral azaferrocenes via chiral ligand-mediated ring- and lateral lithiations2003
- Author(s)
  T.Fukuda, K.Imazato, M.Iwao
- Journal Title
  
  Tetrahedron Letters 44-40
  
  Pages: 7503-7506
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Synthesis and Structure-Activity Relatioship Study of Lamellarin Derivatives2002
- Author(s)
  Fumito Ishibashi, Shinji Tanabe, Tatsuya Oda, Masatomo Iwao
- Journal Title
  
  Journal of Natural Products 65・4
  
  Pages: 500-504
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Optional ortho and lateral lithiations of 4,4-dimethyl-2-(o-tolyl)oxazolines2002
- Author(s)
  N.Tahara, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron Letters 43-50
  
  Pages: 9069-9072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Synthesis and Structure-Activity Relatioship Study of Lamellarin Derivatives2002
- Author(s)
  Fumito Ishibashi, Shinji Tanabe, Tatsuya Oda, Masatomo Iwao
- Journal Title
  
  Journal of Natural Products 65-4
  
  Pages: 500-504
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Journal Article] Optional ortho and lateral lithiations of 4,4-dimethyl-2-(o-tolyl)oxazolines2002
- Author(s)
  N.Tahara, T.Fukuda, M.Iwao
- Journal Title
  
  Tetrahedron Letters 43・50
  
  Pages: 9069-9072
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14580612
[Patent] 第四世代EGFRチロシンキナーゼ阻害剤2017
- Inventor(s)
  岩尾正倫、福田勉、石橋郁人　ほか5名
- Industrial Property Rights Holder
  国立大学法人　長崎大学　ほか２法人
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-064866
- Filing Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-26293028
[Patent] 抗癌活性物質2012
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉、長谷川寛夫
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2012-01-17
- Overseas
- Data Source
  KAKENHI-PROJECT-20310135
[Patent] ベンゾ[g][1]ベンゾピラノ[4,3-b]インドール-6(13H)-オン骨格を持つ抗癌活性化合物2011
- Inventor(s)
  岩尾正倫, 石橋郁人, 福田勉
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2011-01-17
- Data Source
  KAKENHI-PROJECT-20310135
[Patent] ベンゾ[g]ベンゾピラノ[4,3-b]インドール-6-(13H)-オン骨格を持つ抗癌活性化合物2011
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2011-01-17
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 軸不斉構造を持つ12-および16-クロロラメラリンN誘導体の合成と分割2016
- Author(s)
  吉岡美妃子, 白川千尋, 福田勉, 岩尾正倫
- Organizer
  第46回複素環化学討論会
- Place of Presentation
  金沢歌劇座 (石川県金沢市)
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] BIQ骨格を持つ新規トポイソメラーゼI阻害剤の設計・合成・活性評価2016
- Author(s)
  吉岡直樹, 松尾祐理, 松岡冬樹, 福田勉, 岩尾正倫
- Organizer
  第34回メディシナルケミストリーシンポジウム
- Place of Presentation
  つくば国際会議場 (茨城県つくば市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 12-および16-クロロラメラリン N 誘導体の合成研究2016
- Author(s)
  吉岡美妃子, 白川千尋, 福田勉, 岩尾正倫
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] BIQ 骨格を持つ新規トポイソメラーゼI阻害剤の設計と合成2016
- Author(s)
  吉岡直樹, 松岡冬樹, 福田勉, 岩尾正倫
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 光学活性ハロゲノラメラリンNの合成と分割2016
- Author(s)
  白川千尋, 吉岡美妃子, 福田勉, 岩尾正倫
- Organizer
  日本化学会第96春季年会 (2016)
- Place of Presentation
  同志社大学京田辺キャンパス (京都府京田辺市)
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 海洋天然物ラメラリンNの20位および21位改変アナローグの合成研究2016
- Author(s)
  高翔, 吉田祐樹, 福田勉, 岩尾正倫
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] アザラメラリン N 誘導体の効率的合成2016
- Author(s)
  中原茜, 吉田昇太, 安在瑞穂, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] ポリアリールピロール誘導体の位置選択的合成法の開発2015
- Author(s)
  安在瑞穂, 福田勉, 岩尾正倫
- Organizer
  第52回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 軸不斉を持つブロモラメラリンN誘導体の合成と光学分割2015
- Author(s)
  福田勉, 白川千尋, 岩尾正倫
- Organizer
  第４５回複素環化学討論会
- Place of Presentation
  早稲田大学国際会議場 (東京都新宿区)
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] ラメラリンF環部へのブロモ基の位置選択的導入と光学分割2015
- Author(s)
  白川千尋, 福田勉, 岩尾正倫
- Organizer
  第52回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 海洋天然物ラメラリンNの位置選択的ブロモ化2014
- Author(s)
  徳島慶治, 福田勉, 岩尾正倫
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 新規骨格トポイソメラーゼ I 阻害剤BIIQの設計と合成2014
- Author(s)
  松岡冬樹, 福田勉, 岩尾正倫
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 化学療法基盤支援活動「プロテインキナーゼ (PK) 阻害活性の評価」2014
- Author(s)
  西谷直之, 岩尾正倫, 上原至雅
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第３回シンポジウム　アカデミアからの抗がん剤創薬に向けて　天然物の有効利用
- Place of Presentation
  万国津梁館 (沖縄県名護市)
- Year and Date
  2014-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 2,4-ジアリールピロール誘導体の位置選択的合成法の開発2014
- Author(s)
  安在瑞穂, 福田勉, 岩尾正倫
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 海洋天然物ラメラリンを先導物質とする抗がん剤探索2014
- Author(s)
  岩尾正倫
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第３回シンポジウム　アカデミアからの抗がん剤創薬に向けて　天然物の有効利用
- Place of Presentation
  万国津梁館 (沖縄県名護市)
- Year and Date
  2014-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] Laurent Meijer,光学活性16-メチルラメラリンNの絶対配置の決定とプロテインキナーゼ阻害活性評価2012
- Author(s)
  吉田賢佑, 糸山諒介, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ルキアノールA,Bの全合成と生物活性評価2012
- Author(s)
  高村香, 松尾悠未, 田中文菜, 福田勉, 岩尾正倫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多置換ピロール誘導体の位置選択的合成法の開発2012
- Author(s)
  小松原理志, 福田勉, 岩尾正倫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 光学活性16-メチルラメラリンNの絶対配置の決定とプロテインキナーゼ阻害活性評価2012
- Author(s)
  吉田賢佑, 糸山諒介, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 薗頭反応を利用したピラノ[3,4-6]ピロール-7(1H)-オン骨格構築法の開発2012
- Author(s)
  福田勉, 小牟禮稔, 岩尾正倫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Optional Synthesis of 2- or 5-Substituted 3-Bromopyrroles via Bromine-Lithium Exchange of N-Benzenesulfonyl-2,4-dibromopyrrole2011
- Author(s)
  T.Fukuda, M.Iwao
- Organizer
  23rd International Gongress on Heterocyclic Chemistry (ICHC 2011)
- Place of Presentation
  Glasgow, Scotland
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ルキアノールA, Bの全合成2011
- Author(s)
  高村香, 松尾悠未, 福田勉, 岩尾正倫
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリンN誘導体の軸性キラリティーとプロテインキナーゼ阻害活性2011
- Author(s)
  糸山諒介, 吉田賢佑, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Optional Synthesis of 2-or 5-Substituted 3-Bromopyrroles via Bromine-Lithium Exchange of N-Benzenesulfonyl-2, 4-dibromopyrrole2011
- Author(s)
  Tsutomu Fukuda, and Masatomo Iwao
- Organizer
  23rd International Congress on Heterocyclic Chemistry
- Place of Presentation
  Glasgow, Scotland
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] N-ベンゼンスルホニル-4-ブロモ-2-リチオピロールの任意の2位および5位選択的求電子置換反応2011
- Author(s)
  福田勉, 岩尾正倫
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多様性を指向したラメラリン骨格構築法の開発2011
- Author(s)
  小松原理志, 福田勉, 岩尾正倫
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリンN誘導体の軸性キラリティーとプロテインキナーゼ阻害活性2011
- Author(s)
  糸山諒介, 吉田賢佑, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design, Synthesis, and Evaluation of Benzo[ g][ 1] benzopyrano[ 4, 3-b] indol-6(13H)-one(BBPI) Ring System as a New Design, Scaffold of Antitumor Agents2011
- Author(s)
  Yusuke Nanjo, Masahiro Fujimoto, Tsutomu Fukuda, Fumito Ishibashi, and Masatomo Iwao
- Organizer
  8th AFMC International Medicinal Chemistry Symposium Frontier of Medicinal Science
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ルキアノールA, Bの全合成2011
- Author(s)
  高村香, 松尾悠未, 福田勉, 岩尾正倫
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design, Synthesis, and Evaluation of Benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one (BBPI) Ring System as a New Scaffold of Antitumor Agents2011
- Author(s)
  Y.Nanjo, M.Fujimoto, T.Fukuda, F.Ishibashi, M.Iwao
- Organizer
  8th AFMC International Medicinal Chemistry Symposium Frontier of Medicinal Science (AIMECS11)
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] N-ベンゼンスルホニル-4-ブロモ-2-リチオピロールの任意の2位および5位選択的求電子置換反応2011
- Author(s)
  福田勉, 岩尾正倫
- Organizer
  日本化学会第91春季年会
- Place of Presentation
  神奈川大学(神奈川)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多様性を指向したラメラリン骨格構築法の開発2011
- Author(s)
  小松原理志, 福田勉, 岩尾正倫
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム 2P-30
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 軸不斉を持つ海洋天然物ラメラリンNの合成と光学分割2010
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  日本化学会第90回春期年会 2PB-124
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 軸不斉を持つ海洋天然物ラメラリンNの合成と光学分割2010
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪府大阪市)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都テルサ(京都)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] N-ベンゼンスルホニル-2,4-ジブロモピロールの位置選択的臭素-リチウム交換反応2010
- Author(s)
  福田勉, 岩尾正倫
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪府大阪市)
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 光学活性ラメラリンN誘導体の合成2010
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  第40回複素環化学討論会
- Place of Presentation
  仙台市民会館(宮城県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 軸不斉を持つ海洋天然物ラメラリンNの合成と光学分割2010
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  日本化学会第90春季年会講演要旨集
- Place of Presentation
  近畿大学(大阪)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 光学活性ラメラリンN誘導体の合成2010
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  第40回複素環化学討論会 1P-023
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Synthesis and Optical Resolution of Lamellarin N Derivatives2010
- Author(s)
  Ryosuke Itoyama, Takeshi Ohta, Tsutomu Fukuda, Masatomo Iwao
- Organizer
  Nagasaki Symposium on Nano-Dynamics 2010(NSND-2010)
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都テルサ(京都府)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design and Synthesis of Novel Lamellarin D Analogues Targeting Topoisomerase I2010
- Author(s)
  Takeshi Ohta, Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Organizer
  Nagasaki Symposium on Nano-Dynamics 2010(NSND-2010)
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 20位および21位をメチレンジオキシ化したラメラリンN誘導体の合成2010
- Author(s)
  小牟禮稔, 糸山諒介, 福田勉, 岩尾正倫
- Organizer
  2010年日本化学会西日本大会
- Place of Presentation
  熊本大学(熊本県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 5-アザラメラリンD誘導体の合成2010
- Author(s)
  南條佑介, 益田亜紀, 福田勉, 岩尾正倫
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  近畿大学(大阪府大阪市)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Synthesis and Regioselective Functionalization of 1H-Benz[g]indole Ring System2010
- Author(s)
  Yusuke Nanjo, Tsutomu Fukuda, Masatomo Iwao
- Organizer
  Nagasaki Symposium on Nano-Dynamics 2010(NSND-2010)
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] N-ベンゼンスルホニル-3-ブロモピロールの位置選択的リチオ化-官能化 : 動的制御に基づく任意の位置選択的リチオ化-官能化2009
- Author(s)
  福田勉, 岩尾正倫
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学理工学部船橋キャンパス(千葉県船橋市)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 光学分割を指向したラメラリンN誘導体の合成2009
- Author(s)
  糸山諒介, 太田剛, 福田勉, 岩尾正倫
- Organizer
  日本化学会西日本大会2009
- Place of Presentation
  愛媛大学(愛媛県松山市)
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリンα 20-サルフェートおよびその類縁体の合成2009
- Author(s)
  福田勉, 佐伯将, 太田剛, 岩尾正倫
- Organizer
  第39回複素環化学討論会, 10-16
- Place of Presentation
  柏
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリンα20-サルフェートおよびその類縁体の合成2009
- Author(s)
  福田勉, 佐伯将, 太田剛, 岩尾正倫
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(千葉)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] N-ベンゼンスルホニル-3-ブロモピロールの位置選択的リチオ化-官能化 : 2位選択的リチオ化-官能化とラメラリン類合成への応用2009
- Author(s)
  太田剛, 福田勉, 岩尾正倫
- Organizer
  日本化学会第89春季年会
- Place of Presentation
  日本大学理工学部船橋キヤンパス(千葉県船橋市)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ピロロ[2,1-a]フタラジン骨格構築法および位置選択的置換基導入法の開発2009
- Author(s)
  益田亜紀, 福田勉, 岩尾正倫
- Organizer
  日本化学会西日本大会2009
- Place of Presentation
  愛媛大学(愛媛県松山市)
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリン α 20-サルフェートおよびその類縁体の合成2009
- Author(s)
  福田勉, 佐伯将, 太田剛, 岩尾正倫
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(千葉県柏市)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 1H-ベンズ[g]インドール骨格構築法および位置選択的置換基導入法の開発2009
- Author(s)
  南條佑介, 福田勉, 岩尾正倫
- Organizer
  日本化学会西日本大会2009
- Place of Presentation
  愛媛大学(愛媛県松山市)
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ラメラリンDをモデルとする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第18回万有福岡シンポジウム
- Place of Presentation
  九州大学(福岡市)
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 新規抗がん剤の創製を指向したラメラリンD類縁体の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  日本化学会第88春季年会
- Place of Presentation
  立教大学(東京都豊島区)
- Year and Date
  2008-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] N-ベンゼンスルホニル-3-ブロモピロールのリチオ化-官能化における位置選択性の制御2008
- Author(s)
  福田勉, 太田剛, 岩尾正倫
- Organizer
  第38回複素環化学討論会
- Place of Presentation
  広島県民文化センターふくやま(広島県福山市)
- Year and Date
  2008-11-23
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design and Synthesis of Lamellarin D Analogues as New Anticancer Agents2008
- Author(s)
  T., Ohta, T., Fukuda, F., Ishibashi, M., Iwao
- Organizer
  88th Spring Annual meeting of the Chemical Society of Japan
- Place of Presentation
  Tokyo
- Year and Date
  2008-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会 P-44
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ラメラリンDをモデルとする新規トポイソメラーゼI阻害剤の設計と合成,2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第18回万有福岡シンポジウム
- Place of Presentation
  九州大学(福岡)
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会講演要旨集
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design and synthesis of novel antitumor compounds based on a marine natural product,lamellarin D2007
- Author(s)
  T., Ohta, T., Fukuda, F., Ishibashi, M., Iwao
- Organizer
  37th Congress of Heterocyclic Chemistry
- Place of Presentation
  Nagano
- Year and Date
  2007-10-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] Development of Cross-coupling Reaction of N-Benzenesulfony1-3,4-dibromopyrrole and Its Application to the Synthesis of Lamellarins O,P,Q,and R2007
- Author(s)
  E., Sudo, T., Fukuda, M., Iwao
- Organizer
  87th Spring Annual meeting of the Chemical Society of Japan
- Place of Presentation
  Osaka
- Year and Date
  2007-03-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] 海洋天然物ラメラリンDを基盤とする新規抗腫瘍活性物質の設計および合成2007
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第37回複素環化学討論会
- Place of Presentation
  長野市若里市民文化ホール(長野県長野市)
- Year and Date
  2007-10-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] N-ベンゼンスルホニル-3,4-ジブロモピロールのクロスカップリンク反応の開発とラメラリンO,P,Q,R合成への応用2007
- Author(s)
  須藤英一, 福田勉, 岩尾正倫
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  関西大学(大阪府吹田市)
- Year and Date
  2007-03-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] 海洋天然物ラメラリンα20-サルフェートの全合成2006
- Author(s)
  山口智裕, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第36回複素環化学討論会
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2006-11-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] Efficient total syntheses of polycyclic marine alkaloids, lamellarins2006
- Author(s)
  T., Fukuda, F., Ishibashi, M., Iwao
- Organizer
  The Fukuoka Symposium - New Horizon of Natural Product and Biological Chemistries
- Place of Presentation
  Fukuoka
- Year and Date
  2006-07-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] Total Synthesis of the Marine Natural Product Lamellarin a 20-sulfate2006
- Author(s)
  T., Yamaguchi, T., Fukuda, F., Ishibashi, M., Iwao
- Organizer
  36th Congress of Heterocyclic Chemistry
- Place of Presentation
  Nagasaki
- Year and Date
  2006-11-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] Efficient total syntheses of polycyclic marine alkaloids,lamellarins2006
- Author(s)
  Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Organizer
  The Fukuoka Symposium-New Horizon of Natural Product and Biological Chemistries
- Place of Presentation
  九州大学医学部百年講堂(福岡県福岡市)
- Year and Date
  2006-07-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18510188
[Presentation] [1]ベンゾピラノ[3,4-b]ピロール-4(3H)-オンを鍵中間体とするラメラリン合成 (2)
- Author(s)
  原田一生, 片江貴俊, 福田勉, 岩尾正倫
- Organizer
  日本化学会第95春季年会 (2015)
- Place of Presentation
  日本大学理工学部船橋キャンパス (千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 6-ハロゲノラメラリンN誘導体の合成
- Author(s)
  徳島慶治, 福田勉, 岩尾正倫
- Organizer
  日本化学会第95春季年会 (2015)
- Place of Presentation
  日本大学理工学部船橋キャンパス (千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 2,4-ジアリールピロール誘導体の位置選択的合成法の開発と応用
- Author(s)
  安在瑞穂, 福田勉, 岩尾正倫
- Organizer
  第４４回複素環化学討論会
- Place of Presentation
  札幌市民ホール (北海道札幌市)
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 海洋天然物ラメラリンNのA環部改変アナローグの効率的合成
- Author(s)
  梅木鉄平, 徳島慶治, 福田勉, 岩尾正倫
- Organizer
  第４４回複素環化学討論会
- Place of Presentation
  札幌市民ホール (北海道札幌市)
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] [1]ベンゾピラノ[3,4-b]ピロール-4(3H)-オンを鍵中間体とするラメラリン合成 (1)
- Author(s)
  片江貴俊, 原田一生, 福田勉, 岩尾正倫
- Organizer
  日本化学会第95春季年会 (2015)
- Place of Presentation
  日本大学理工学部船橋キャンパス (千葉県船橋市)
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] 光学活性ラメラリンN誘導体の合成
- Author(s)
  糸山諒介, 福田勉, 岩尾正倫
- Organizer
  第40回複素環化学討論会
- Place of Presentation
  仙台市民会館(宮城)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 高活性トポイソメラーゼI阻害剤BBPIの水溶性誘導体の設計・合成・評価
- Author(s)
  佐々木翔, 夏井裕子, 仲山隆太, 藤秀人, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  札幌市民ホール (北海道札幌市)
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-26293028

1. FUKUDA Tsutomu (80295097)

# of Collaborated Projects: 5 results

# of Collaborated Products: 123 results
2. ISHIBASHI Fumito (10192486)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
3. HASEGAWA Hiroo (00398166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. UNNO Hideaki (10452872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. UEHARA Yoshimasa (50160213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NISHIYA Naoyuki (10286867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 上平憲 (80108290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 神山陽香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 吉居陽香

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
10. 久保嘉直

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

IWAO Masatomo 岩尾 正倫

Research Projects

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Development of EGFR-Tyrosine Kinase Inhibitors Effective for Non-Small Cell Lung Cancer Resistant to GefitinibPrincipal Investigator

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Possibility of a new synthetics from lamellarins: anti-leukemic and integrase-inhibitory effects against HTLV-1-related leukemia cells.

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Elucidation and Control of the Molecular Mechanism of Action of the Multifunctional Antitumor Agents LamellarinsPrincipal Investigator

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Design and Synthesis of New Antitumor Agents Using Marine Natural Product Lamellarin as A Structural MotifPrincipal Investigator

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Chemical Synthesis of marine pyrrole alkaloids effective against multidrug-resistant cancersPrincipal Investigator

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Creation of novel antitumor agents having DNA topoisomerase inhibition activityPrincipal Investigator

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STUDIES ON THE SYNTHESIS OF ANTITUMOR PYRROLOIMINOQUINONE MARINE ALKALOIDSPrincipal Investigator

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[Journal Article] Synthesis of Lamellarins via Regioselective Assembly of 1,2-Diarylated [1]Benzopyrano[3,4-b]pyrrol-4(3H)-one Core2017

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[Journal Article] Regioselective Synthesis of 2,4-Differentially Arylated Pyrroles and Its Application to the Synthesis of Lamellarins2016

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[Journal Article] A Synthesis of Lamellarins via Regioselective Assembly of 1,2,3-Differentially Substituted 5,6-Dihydropyrrolo[2,1-a]isoquinoline Core2015

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[Journal Article] Synthesis of Non-Steroidal Estrogen Receptor Antagonists R1128 A, B, C, and D via an Oxazoline-Promoted Iterative ortho-Lithiation Strategy2012

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[Journal Article] Synthesis of non-steroidal estrogen receptor antagonists R1128 A, B, C, and D via an oxazoline-promoted iterative ortho-lithiation strategy2012

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[Journal Article] Infection of XC cells by MLVs and ebola virus is endosome-dependent but acidification-independent2011

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IWAO Masatomo 岩尾正倫