• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

SUGIBAYASHI KENJI  杉林 堅次

ORCIDConnect your ORCID iD *help
… Alternative Names

SUGIBAYASHI Kenji  杉林 堅次

SUGIBAYASHI Kenji.Ph.D.  杉林 堅次

杉林 堅次  スギバヤシ ケンジ

Less
Researcher Number 00105834
Other IDs
Affiliation (Current) 2025: 城西国際大学, イノベーションベース, 特別栄誉教授
2025: 城西大学, 薬学部, 特命教授
Affiliation (based on the past Project Information) *help 2003 – 2011: 城西大学, 薬学部, 教授
1998 – 2001: 城西大学, 薬学部, 教授
1997: Josai University, Faculty of Pharmaceutical Sciences, Associate Professor, 薬学部, 助教授
1995: 城西大学, 薬学部, 助教授
1987 – 1988: 城西大学, 薬学部, 講師
Review Section/Research Field
Principal Investigator
医薬分子機能学 / Physical pharmacy / Physical pharmacy / Medical pharmacy
Except Principal Investigator
Physical pharmacy
Keywords
Principal Investigator
MTT assay / high throughput screening / 三次元培養ヒト皮膚モデル / MTT試験 / 皮膚刺激 / electroporation / iontophoresis / targeted delivery system / cisplatin / blood vessel-embolism … More / oily drug carrier / 粘性油性製剤 / 薬物担体 / 癌部位集積性 / シスプラチン / 癌部集積性 / 組織滞留性 / 油性薬物担体 / 塞栓能 / Kinetic analysis / Skin irritation / モルモット / ヘアレスマウス / Hill式 / 塩化セチルピリジニウム / 皮膚刺激性 / 速度論的解析 / 皮膚刺激性評価法 / サイトカイン / 速度論 / skin irritation / quartz crystal microbalance / penetration enhancement / alternative skin / Skin permeation / three-dimensional cultured human skin model / skin metabolism / 経皮吸収促進剤 / skin permeation / High Throughput Screening / 水晶発振子 / 透過促進 / 代替皮膚 / High Throghput Screening / 皮膚透過 / 三次元培養皮膚モデル / transdermal absorption / jet injector / intravenous infusion / powder injector / liquid injector / 経皮吸収 / jet incector / 点滴注射剤 / 微粒子製剤 / 微粒子送達 / 高分子医薬品 / 皮膚透過性改善 / ドラッグデリバリーシステム / 経皮パッチ / エレクトロポレーション / マイクロニードル / 経附属器官ルート / 体内動態 / PLGAナノスフェア / 酸化チタン微粒子 / ナノマテリアル / hydrophilic pathway / 経付属器官ルート / 皮膚透過性 / マイクロスフィア / ナノスフィア / TDDS / 経皮送達 / ナノスフェア / ナノベシクル … More
Except Principal Investigator
enhancing effect / skin permeation / iontophoresis / jet injector / 吸収促進効果 / 皮膚透過性 / イオントフォレ-シス / ジェットインジェクター Less
  • Research Projects

    (7 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (12 People)
  •  Biopharmaceutical delivery using transdermal patches having MN and EP systemsPrincipal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Josai University
  •  Nanovehicle/nanoparticle delivery through skinPrincipal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Josai University
  •  Research for establishment of evaluation method for the skin irritation using a Three-Dimensional Cultured Human Skin Model instead of in vivo results.Principal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Josai University
  •  Utility of the three-dimensional cultured human skin model as a tool to evaluate rapid determination of skin permeation of drag and skin irritation.Principal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Josai University
  •  Study on alternation preparations for intravenous infusion systemPrincipal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      医薬分子機能学
    • Research Institution
      Josai University
  •  Transdermal Delivery of Peptide-like Drugs by Iontophoresis with Jet Injection

    • Principal Investigator
      MARIMOTO Yasunori.Ph.D.
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Josai University
  •  Study on oily drug carriers with blood-embolism potentialPrincipal Investigator

    • Principal Investigator
      SUGIBAYASHI Kenji
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Josai University

All 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

  • [Journal Article] A hollow microneedle carrier for enhancing skin penetration of large molecular compounds2011

    • Author(s)
      Nanthida W, Tanasait N, Praneet O, Todo H, Sugibayashi K
    • Journal Title

      Adv Mater. Res.

    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] A hollow microneedle carrier for enhancing skin penetration of large molecular compounds2011

    • Author(s)
      Nanthida Wonglertnirant, Tanasait Ngawhirunpat, Praneet Opanasopit, Hiroaki Todo, K.Sugibayashi
    • Journal Title

      Adv.Mater.Res.

      Volume: 194-196 Pages: 549-553

    • DOI

      10.4028/www.scientific.net/amr.194-196.549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] Transdermal drug delivery by in-skin electroporation using a microneedle array2010

    • Author(s)
      Yan K, Todo H, Sugibayashi K
    • Journal Title

      Int J Pharm

      Volume: 397 Pages: 77-83

    • NAID

      120005518465

    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] Transdermal drug delivery by in-skin electroporation using a microneedle array.2010

    • Author(s)
      Yan K, Todo H, Sugibayashi K.
    • Journal Title

      Int J Pharm.

      Volume: 397 Pages: 77-83

    • NAID

      120005518465

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] 薬物の皮膚透過促進技術:エレクトロポレーション、マイクロニードル単独効果、そしてマイクロニードル電極アレイを用いたエレクトロポレーションの効果2009

    • Author(s)
      杉林堅次
    • Journal Title

      Progress in drug delivery system XVIII

      Pages: 5-9

    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] 薬物の皮膚透過促進技術:エレクトロポレーション、マイクロニードル単独効果、そしてマイクロニードル電極アレイを用いたエレクトロポレーションの効果2009

    • Author(s)
      杉林堅次
    • Journal Title

      Progress in drug delivery system

      Volume: XVIII Pages: 5-9

    • Data Source
      KAKENHI-PROJECT-21590045
  • [Journal Article] 紫外線防御試験法の国際的動向と紫外線防御剤の開発の課題: 化粧品に用いられるナノ粒子の曝露と安全性問題のあり方2008

    • Author(s)
      杉林 堅次
    • Journal Title

      Fragrance journal 10月号

      Pages: 38-41

    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] Safety evaluation of titanium dioxide nanoparticles by their a bsorption and elimination profiles2008

    • Author(s)
      Kenji Sugibayashi, Hiroaki Todo, Eriko Kimura
    • Journal Title

      J. Toxicol. Sci. 33

      Pages: 293-298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] 皮膚を介した薬物デリバリー2008

    • Author(s)
      杉林 堅次、杉野 雅浩
    • Journal Title

      化学工業 5月号

      Pages: 72-78

    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] 紫外線防御試験法の国際的動向と紫外線防御剤の開発の課題 : 化粧品に用いられるナノ粒子の曝露と安全性問題のおり方2008

    • Author(s)
      杉林 堅次
    • Journal Title

      FRAGRANCE JOURNAL 10月号

      Pages: 38-41

    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] 有効性を発揮させるための剤形構築、皮膚浸透・経皮吸収に及ぼす剤形の影響2007

    • Author(s)
      杉林 堅次
    • Journal Title

      日本香粧品学会誌 30

      Pages: 261-265

    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] Kinetic Analysis on the Skin Disposition of Cytotoxicity as an Index of Skin Irritation Produced by Cetylpyridinium Chloride : Comparison of In Vitro Data using a Three-Dimensional Cultured Human Skin Model with In Vivo Results in Hairless Mice.2006

    • Author(s)
      Kano S, Sugibayashi K.
    • Journal Title

      Pharmaceutical Research 23・2

      Pages: 329-335

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590137
  • [Journal Article] Kinetic Analysis on the Skin Disposition of Cytotoxicity as an Index of Skin Irritation Produced by Cetylpyridinium Chloride : Comparison of In Vitro Data using a Three-Dimensional Cultured Human Skin Model with In Vivo Results in Hairless Mice.2006

    • Author(s)
      Kano S, Sugibayashi K.
    • Journal Title

      Pharmaceutical Research 23(2)

      Pages: 329-335

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590137
  • [Journal Article] SAFETY EVALUATION OF TITANIUM DIOXIDE NANOPARTICLES BY THEIR ABSORPTION AND ELIMINATION PROFILES

    • Author(s)
      Kenji SUGIBAYASHI, Hiroaki TODO, Eriko KIMURA
    • Journal Title

      Journal of Toxicological Sciences (In press)

    • NAID

      110006862205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Journal Article] SAFETY EVALUATION OF TITANIUM DIOXIDE NANOPARTICLES BY THEIR ABSORPTION AND ELIMINATION PROFILES

    • Author(s)
      Kenji SUGIBAYASHI, Hiroaki TODO and Eriko KIMURA
    • Journal Title

      Journal of Toxicological Sciences

      Pages: 0-0

    • NAID

      110006862205

    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] マイクロニードル電極を用いたエレクトロポレーション適用によるナノ粒子の皮内到達の可能性2011

    • Author(s)
      喜島小翔、Yan Keshu、藤堂浩明、杉林堅次
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] マイクロニードル電極を用いたエレクトロポレーションによる高分子薬物の経皮送達2009

    • Author(s)
      杉林堅次
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡コンベンションアーツセンター
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] 経皮吸収促進技術とその評価法2009

    • Author(s)
      杉林堅次
    • Organizer
      半固形製剤 教育研修会
    • Place of Presentation
      東京、コスモステクニカルセンター
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] 薬物の皮膚透過性促進技術:エレクトロポレーション、マイクロニードル単独効果、そしてマイクロニードル電極アレーを用いたエレクトロポレーションの効果2009

    • Author(s)
      杉林堅次
    • Organizer
      第18回DDSカンファランス
    • Place of Presentation
      静岡コンベンションアーツセンター
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] 経皮吸収促進技術とその評価法、半固形製剤2009

    • Author(s)
      杉林堅次
    • Organizer
      教育研修会
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] 微粒子酸化チタンの体内分布と毒性評価2009

    • Author(s)
      木村 恵理子、藤堂 浩明、杉林 堅次
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] マイクロニードル電極を用いたエレクトロポレーションによる高分子薬物の経皮送達2009

    • Author(s)
      杉林堅次
    • Organizer
      日本薬剤学会第24回
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] マイクロニードル電極を用いたエレクトロポレーションによる高分子薬物の経皮送達2009

    • Author(s)
      杉林堅次
    • Organizer
      第25回日本DDS学会
    • Data Source
      KAKENHI-PROJECT-21590045
  • [Presentation] Transdermal and intradermal delivery of high-molecular compounds: cut-off size of chemical compounds by skin and cutaneous vascular membranes2008

    • Author(s)
      Kenji Sugibayashi
    • Organizer
      France Japan 8th Drug Delivery Symposium
    • Place of Presentation
      Cannes, France
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] ナノ粒子の皮膚暴露・皮膚浸透の可能性を考える2008

    • Author(s)
      杉林 堅次
    • Organizer
      第15回 日本免疫毒性学会
    • Place of Presentation
      船堀、東京
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] Transdermal and intradermal delivery of high-molecular compounds : cut-off size of chemical compounds by skin and cutaneous vascular membranes2008

    • Author(s)
      杉林 堅次
    • Organizer
      France Japan 8^<th> Drug Delivery Symposium
    • Place of Presentation
      Cannes, France
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] 水溶性高分子およびナノスフェアの皮膚浸透ルートおよび浸透性に関する研究2007

    • Author(s)
      安野 浩崇、藤堂 浩明、杉林 堅次
    • Organizer
      第127年会日本薬学会
    • Place of Presentation
      富山
    • Data Source
      KAKENHI-PROJECT-18590036
  • [Presentation] Enhanced skin permeationからinjection-like deliveryへ2006

    • Author(s)
      藤堂 浩明、杉林 堅次
    • Organizer
      第22回 日本DDS学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18590036
  • 1.  TODO Hiroaki (10383184)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 11 results
  • 2.  ISHII Hiroshi (90383182)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  NATSUME Hideshi (40180533)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  HASEGAWA Tetsuya (50245148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KIMURA Masayuki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ISHIBASHI Takuya
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MARIMOTO Yasunori.Ph.D. (90001057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NUMAJIRI Sachihiko.M.S. (40245147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TAKAYAMA Kozo (00130758)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HATANAKA Tomomi (10198749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  JUNI Kazuhiko (80111178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KIMURA Masayuki.Ph.D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi