SEKIGUCHI Takeshi 関口武司

Researcher Number	00108193
Other IDs
Affiliation (based on the past Project Information) *help	2008 – 2010 : いわき明星大学, 科学技術学部, 教授 2000 – 2003 : いわき明星大学, 理工学部, 教授
Review Section/Research Field	Except Principal Investigator Structural biochemistry / Structural biochemistry
Keywords	Except Principal Investigator I-motif of G-quartets / DNA / アミノアシルtRNA合成酵素 / base-intercalated duplex / RNAワールド / 平行二重らせん / X線結晶解析 / 5-ホルミルシトシン / RNA world / 5-ホルミルウラシル … More

Structure and function of two different threonyl-tRNA synthetases of crenarchaea
- Principal Investigator
  
  TAKENAKA Akio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Iwaki Meisei University
Structural basis for design of functional molecules in the DNA/RNA world
- Principal Investigator
  
  TAKENAKA Akio
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  TOKYO INSTITUTE OF TECHNOLOGY

All 2010 2009 2008

All Journal Article Presentation Book

[Book] 耐熱酵素のさらなる安定性向上,酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(小宮山眞監修)2010
- Author(s)
  竹中章郎・関口武司
- Total Pages
  5
- Publisher
  株式会社エヌ・ティー・エス(東京)
- Data Source
  KAKENHI-PROJECT-20570104
[Book] 耐熱酵素のさらなる安定性向上ISBN978-4-86043-271-3, 518-522(酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-)(小宮山眞監修)東京2010
- Author(s)
  竹中章郎・関口武司著
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Actinohivin: specific amino acid residues essential foranti-HIV activity2010
- Author(s)
  Masaru Tsunoda, Kaoru Suzuki, Akio Takenaka, Takeshi Sekiguchi, Hideaki Umeyama, Jun Hirabayashi, Satoshi Omura, Haruo Tanaka
- Journal Title
  
  J.Antibiot. 106
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystallo-graphic study of wild type carbonic anhydrase αCA1 from Chlamydomonas reinhardtii2010
- Author(s)
  Kaoru Suzuki, Satoru Shimizu, Ella Czarina Magat Juan, Takahiro Miyamoto, Fang Zhang, Md. Mominul Hoque, Yoshiteru Sato, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. F66
  
  Pages : 1082-1085
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystallization and preliminary crystallographic studies of putative 3'-terminal phosphate cyclase from the crenarchaeon Sulfolobus tokodaii2009
- Author(s)
  S.Shimuzu, T.Sekiguchi, A.Takenaka
- Journal Title
  
  Acta Crystallogr. F65
  
  Pages : 565-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Two complementary enzymes for threonylation of tRNA in crenarchaeota; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2009
- Author(s)
  Satoru Shimizu, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Yoshiteru Sato, Md. Mominul Hoque, Kaoru Suzuki, Tsubasa Sagara, Masaru Tsunoda, Takeshi Sekiguchi, Anne-Catherine Dock-Bregeon, Dino Moras, Akio Takenaka
- Journal Title
  
  J.Mol.Biol. 394
  
  Pages : 286-296
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Mechanism by which the lectin actinohivin blocks HIV infection of target cells2009
- Author(s)
  Haruo Tanaka, Harumi Chiba, Junji Inokoshi, Atsushi Kuno, Takahiro Sugai, Atsushi Takahashi, Yukishige Ito, Masaru Tsunoda, Kaoru Suzuki, Akio Takenaka, Takeshi Sekiguchi, Hideaki Umeyama, Jun Hirabayashi, Satoshi Omura
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages : 15633-15638
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystal structure of D-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate D-3-hydroxybutyrate NAD^+2009
- Author(s)
  Md. Mominul Hoque, Satoru Shimizu, Ella Czarina Magat Juan, Yoshiteru Sato, Md. Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Hitoshi Amano, Takeshi Sekiguchi, Masaru Tsunoda, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. F65
  
  Pages : 331-335
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Perform a Function by Supplementing Their Defects to Each Other in Crenarchaea2009
- Author(s)
  S.Shimuzu, T.Sekiguchi, A.Takenaka
- Journal Title
  
  Acta Crystallogr. A65
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystallization preliminary crystallographic studies of putative RNA 3'-terminal phosphate cyclase from crenarchaeon Sulfolobus tokodaii2009
- Author(s)
  Satoru Shimizu, Masanori Ohki, Nami Okubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. F65
  
  Pages : 565-570
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Two complementary enzymes for threonylation of tRN in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking cis-eding domain2009
- Author(s)
  Satoru Shimizu, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  J.Mol.Biol., 394
  
  Pages : 286-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Structures of Arthrobacter globiformis urate oxidase-lig complexes2008
- Author(s)
  Ella Czarina Magat Juan, Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. D64
  
  Pages : 815-822
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystallographic study on two types of putative threonyl-tRNA synthetases from crenarchaea Aeropyrum pernix those from Sulfolobus tokodaii2008
- Author(s)
  Satoru Shimizu, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Yoshiteru Sato, Kaoru Suzuki, Masataka Yogiashi, Masaru Tsunoda, Anne-Catherine Dock-Bregeon, Dino Moras, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. F64
  
  Pages : 903-910
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] Crystallization and preliminary crystallographic studies on putative threony1-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodai2008
- Author(s)
  Satoru Shimizu, . . . . . . . . . . Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallography F64
  
  Pages : 903-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570104
[Journal Article] The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before after NAD^+ acetate binding suggest a dynamical reaction mechanism as a member of the SDR family2008
- Author(s)
  Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
- Journal Title
  
  Acta Crystallogr. D64
  
  Pages : 496-505
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] 古細菌Sulfolobus tokodaii由来トレオニルtRNA合成酵素の精製と結晶化構2010
- Author(s)
  斉藤彰浩, 鈴木薫, 関口武司, 角田大, 竹中章郎
- Organizer
  平成22年度化学系学協会東北大会講演予稿集186
- Place of Presentation
  盛岡
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal structure of anti-HIV actinohivin in complexwith 1, 2-mannobiose2010
- Author(s)
  M.M.Hoque, K.Suzuki, M.Tsunoda, A.Takahashi, T.Sekiguchi, H.Tanaka, A.Takenaka
- Organizer
  日本結晶学会年会講演要旨集,126
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2010
- Author(s)
  A.Takenaka, S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi, A.C.D.Bregeon, D.Moras
- Organizer
  Centre for Chemical Biologyセミナー
- Place of Presentation
  Sheffield大学
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Two complementary enzymes for threonylation of tRNA in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2010
- Author(s)
  A.Takenaka, S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi,, A.C.D.Bregeon, D.Moras
- Organizer
  IGBMC(フランス国立遺伝学分子細胞生物学研究所)セミナー
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Two complementary enzymes for threonylation of tRNA in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2010
- Author(s)
  Takenaka A., Miyashita Y., Sato Y., Dock-Bregeon A.C., Moras D., Sekiguchi T., Shimizu S.
- Organizer
  IGBMCセミナー
- Place of Presentation
  IGBMC(フランス国立遺伝学分子細胞生物学研究所)
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2010
- Author(s)
  Takenaka A., Miyashita Y., Sato Y., Dock-Bregeon A.C., Moras D., Sekiguchi T., Shimizu S.
- Organizer
  化学生物学センターセミナー
- Place of Presentation
  Sheffield大学, Centre for Chemical Biology
- Year and Date
  2010-10-19
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] 放線菌より単離した新規anti-HIV蛋白質アクチノヒビンならびにそのマンノビオースとの複合体のX線構造2009
- Author(s)
  角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
- Organizer
  第82回日本生化学会大会,要旨集4T9p-124P-629
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal Structures of Actinohivin, an Anti-HIV Protein from an Actinomycete, its Complex2009
- Author(s)
  角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
- Organizer
  25th European Crystallographic Meeting, ECM25 (Istanbul) Abstract
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Structure reaction mechanism of an enzyme RNA 3'-terminal phosphate cyclase in tRNA splicing2009
- Author(s)
  竹中章郎, 大木正則, 大久保奈弥, 鈴木薫, 角田大, 関口武司, 清水了
- Organizer
  tRNA Workshop, Aveiro, Portugal
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] RNAプロセシングに関与するタンパク質,RNA3'-末端リン酸基環状化酵素の反応機構2009
- Author(s)
  清水了, 大木正則, 大久保奈弥, 鈴木薫, 角田大, 関口武司, 竹中章郎
- Organizer
  第11回RNA ミーティング,要旨集6
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] 新規抗HIVタンパク質アクチノヒビンのマンノビオースとの共結晶化2009
- Author(s)
  相良翼, 斉藤彰浩, 高橋淳, 鈴木薫, 関口武司, 角田大, 田中晴雄, 竹中章郎
- Organizer
  日本結晶学会2009年度年会,講演要旨集116
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Perform a Function by Supplementing Their Defects to Each Other in Crenarchaea2009
- Author(s)
  S.Shimizu, T.Sekiguchi, A.Takenaka
- Organizer
  European Crystallographic Association
- Place of Presentation
  ECM25, Istanbul,トルコ
- Year and Date
  2009-08-19
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Prefer a Functionby Supplementing Their Defects to Each Other in Crenarchaea2009
- Author(s)
  S.Shimizu, Y.Sato, E.C.M.Juan, Y.Miyashita, T.Sagara, K.Suzuki, M.Tsunoda, T.Sekiguchi, A.C.D.Bregeon, D.Moras, A.Takenaka
- Organizer
  25th European Crystallographic Meeting, ECM25 (Istanbul) Abstract
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] X-Ray analyses of two evolutionarily different threonyl-tRNA synthetases which perform a function by supplementing their defects to each other in crenarchaea2009
- Author(s)
  Satoru Shimizu, Yoshiteru Sato, Ella Czarina Magat Juan, Yu-ichiro Miyashita, Tsubasa Sagara, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Anne-Catherine Dock-Bregeon, Dino Moras, Akio Takenaka
- Organizer
  Acta Crystallogr., A65, s17-s18
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal structures of actinohivin, an anti-HIV proteinfrom an actinomycete, its complex with mannobiose2009
- Author(s)
  角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 田中晴雄, 竹中章郎
- Organizer
  Acta Crystallogr., A65, s149-s150
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Two threonyl-tRNA synthetases with complementary functions ; Crystal structure of ThrRS-1 from Aeropyrum pernix2008
- Author(s)
  Akio Takenaka, . . . . . . . . . Takeshi Sekiguchi
- Organizer
  IUCr2008 Congress and General Assembly
- Place of Presentation
  Osaka
- Year and Date
  2008-08-25
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal structure of α-carbonic anhydrase from Chlamydomonas reinhardtii2008
- Author(s)
  Kaoru Suzuki, Satoru Shimizu, Risa Ohbayashi, Yoshiteru Sato, Akio Takenaka, Takeshi Sekiguchi, Shi-Yuan Yang
- Organizer
  Acta Cryst., A64, C263
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal structures of RNA 3'-terminal phosphate cyclase its complexes with Mg^<2+>+ATP, ATP or Mn^<2+>2008
- Author(s)
  Satoru Shimizu, Masanori Ohki, Nami Ohkubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
- Organizer
  Nucleic Acids Symp Ser.52, 221-222
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Two threonyl-tRNA synthetases with complementaryfunctions ; Crystal structure of ThrRS-1 fromAeropyrum pernix2008
- Author(s)
  Akio Takenaka, Satoru Shimizu, Yu-ichiro Miyashita, Yoshiteru Sato, Ella Czarina Magat Juan, Kaoru Suzuki, Masaru Tsunoda, Anne-Catherine Dock-Bregeon, Dino Moras, Takeshi Sekiguchi
- Organizer
  Acta Cryst., A64, C311
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] Crystal structure of actinohivin ; A novel anti-humanimmunodeficiency virus protein2008
- Author(s)
  角田大, 鈴木薫, 相良翼, 高橋淳, 猪腰淳嗣, 大村智, 関口武司, 竹中章郎, 田中晴雄
- Organizer
  Acta Crystallogr., A64, C237
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] The substrate recognition the catalytic reaction mechanisms of D-3hydroxybutyrate dehydrogenase2008
- Author(s)
  Md Mominul Hoque, Satoru Shimizu, Md Tofazzal Hossain, Tamotsu Yamamoto, Shigeyuki Imamura, Kaoru Suzuki, Masaru Tsunoda, Hitoshi Amano, Takeshi Sekiguchi, Akio Takenaka
- Organizer
  Acta Cryst., A64, C252
- Data Source
  KAKENHI-PROJECT-20570104
[Presentation] RNA splicing related proteins; Crystal structure of RNA 3'-terminal phosphate cyclase2008
- Author(s)
  Satoru Shimizu, Masanori Ohki, Nami Ohkubo, Kaoru Suzuki, Masaru Tsunoda, Takeshi Sekiguchi, Akio Takenaka
- Organizer
  Acta Cryst., A64, C307
- Data Source
  KAKENHI-PROJECT-20570104

1. TAKENAKA Akio (80016146)

# of Collaborated Projects : 2results

# of Collaborated Products : 37results
2. MORAS Dino

# of Collaborated Projects : 1results

# of Collaborated Products : 9results

SEKIGUCHI Takeshi 関口 武司

Research Projects

Research Products

Co-Researchers

Structure and function of two different threonyl-tRNA synthetases of crenarchaea

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural basis for design of functional molecules in the DNA/RNA world

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 耐熱酵素のさらなる安定性向上,酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-(小宮山眞監修)2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 耐熱酵素のさらなる安定性向上ISBN978-4-86043-271-3, 518-522(酵素利用技術大系-基礎・解析から改変・高機能化・産業利用まで-)(小宮山眞監修)東京2010

Author(s)

Publisher

Data Source

[Journal Article] Actinohivin: specific amino acid residues essential foranti-HIV activity2010

Author(s)

Journal Title

Data Source

[Journal Article] Crystallo-graphic study of wild type carbonic anhydrase αCA1 from Chlamydomonas reinhardtii2010

Author(s)

Journal Title

Data Source

[Journal Article] Crystallization and preliminary crystallographic studies of putative 3'-terminal phosphate cyclase from the crenarchaeon Sulfolobus tokodaii2009

Author(s)

Journal Title

Data Source

[Journal Article] Two complementary enzymes for threonylation of tRNA in crenarchaeota; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain2009

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism by which the lectin actinohivin blocks HIV infection of target cells2009

Author(s)

Journal Title

Data Source

[Journal Article] Crystal structure of D-3-hydroxybutyrate dehydrogenase, prepared in the presence of the substrate D-3-hydroxybutyrate NAD^+2009

Author(s)

Journal Title

Data Source

[Journal Article] X-Ray Analyses of Two Evolutionary Different Threonyl-tRNA Synthetases Which Perform a Function by Supplementing Their Defects to Each Other in Crenarchaea2009

Author(s)

Journal Title

Data Source

[Journal Article] Crystallization preliminary crystallographic studies of putative RNA 3'-terminal phosphate cyclase from crenarchaeon Sulfolobus tokodaii2009

Author(s)

Journal Title

Data Source

[Journal Article] Two complementary enzymes for threonylation of tRN in crenarchaeota ; crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking cis-eding domain2009

Author(s)

Journal Title

Data Source

[Journal Article] Structures of Arthrobacter globiformis urate oxidase-lig complexes2008

Author(s)

Journal Title

Data Source

[Journal Article] Crystallographic study on two types of putative threonyl-tRNA synthetases from crenarchaea Aeropyrum pernix those from Sulfolobus tokodaii2008

Author(s)

Journal Title

Data Source

[Journal Article] Crystallization and preliminary crystallographic studies on putative threony1-tRNA synthetases from Aeropyrum pernix and Sulfolobus tokodai2008

Author(s)

Journal Title

Data Source

[Journal Article] The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before after NAD^+ acetate binding suggest a dynamical reaction mechanism as a member of the SDR family2008

Author(s)

Journal Title

Data Source

[Presentation] 古細菌Sulfolobus tokodaii由来トレオニルtRNA合成酵素の精製と結晶化構2010

Author(s)

Organizer

SEKIGUCHI Takeshi 関口武司