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OHNO Masaji
大野 雅二
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Researcher Number
00111550
Affiliation
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1986 – 1990 : 東京大学, 薬学部, 教授
1986 : Faculty of Pharmaceutical Sciences, Univ. of Tokyo, Professor, 薬学部, 教授
1985 : 東京大学, 薬, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy
/
Biological pharmacy
Except Principal Investigator
Chemical pharmacy
/
Biological pharmacy
Keywords
Principal Investigator
ブレオマイシン / コレシストキニン / 酸素活性化 / DNA切断 / 不斉反応 / Pig liver esterase / 精密有機合成 / 抗炎症剤 / 触媒反応 / 不斉シクロプロパン化
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/ Fortimicine / カルベノイド / 豚肝臓エステラーゼ / alkylation / 生命機能 / ホーチミシン / Anti-coagulative / レクチン / Anti- hypertensive / phospholipase 【A_2】 / ミルベマイシン / Phospholipase A_2 / Asymmetric synthesis / Rhizoxin / retrosynthesis / Conformational Drug design / Life function / 触媒的不斉合成 / cyclic hydroboration / β-ラクタム抗生物質 / 0ージメチルホスフィニル基 / キラルルイス酸 / 抗生物質の合成 / enantioselective reaction / Retrosynthesis / 血小板活性化因子 / ヌクレオシド / symmetrization-asymmetrization concept / アリルアルコ-ル / 不斉合成 / Pig live esterase / エスペラミシン / PAF抗体 / 不斉アルキル化反応 / カルバペネム / Nucleoside / ジアルキル亜鉛 / Peptide ynthesis / sulfonamide / (S)-β-hydroxy isobutyric acid / ジエチル亜鉛 / シクロプロパン化反応 / 抗血栓剤 / 1S-メチルPAF / ジメチルホスフィニル基 / 酵素 / L-酒石酸 / Synthesis of antibiotics / オルトチタネ-ト / 2-シス-ジカルボン酸メチルエステル / L-tartaric acid / 1(S)-Me-PAF / catalytic reaction / Symmetrization-asymmetrization concept / ビタミンD / Glutaric acid / Anti-inflammative / 精密有機化学 / 触媒的不斉反応 / chiral Lewis acid / cyclopropanation / ジヨ-ドメタン / Macloride(16員環) / シアロシルグリセロリピド / Vitamine D / 4-シクロヘキセン-1 / Phospholipass A_2 / dialkylzinc / リゾキシン / アバメクチン / ペプチド合成 / スルホンアミド / T細胞 / 癌細胞障害性マクロファ-ジ / 血圧降下剤 / Advanced organic chemistry / 不斉アルキル化 / Platelet Activating Factor / アルキル化反応 / Drug Design / リゾチシン
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More
Except Principal Investigator
トリチル塩 / リパーゼ / 酵素的合成 / PAF / ポリオール類 / 複合系の分子機能 / ラジオイムノアッセイ / 血小板活性化因子 / 複合系の反応制御 / 複合系高次制御 / PAF抗体 / ケテンシリルアセタール / 微生物酵素 / セリン / 複合系の反応設計 / 人工ブレオマイシン / 高選択的反応 / 複合系の反応試剤 / 有機合成化学 / PAF receptor / 複合系の高次制御 / 天然物 / 分岐型2-5A / アプリシアトキシン / Anti-PAF drugs / differentiation / 構造活性相関 / 複合系の反応論的アプロ-チ / 耐熱性フェニルアラニン脱水素酵素 / asthma / 白血球 / アフィディコリン / シスタチオニン / retinoid, differentiation, vitamin A, retinoic acid. teleocidin retinoid / vitamin A / ブレオマイシン / PAFアンタゴニスト / レセプター / leukocytes / RIA / サイトカイニン / 5配位シリコナート / 複合系の構造化学的アプローチ / 複合系の反応論的アプローチ / PAF受容体 / PAF分解酵素 / eosinophils / PAF代謝酵素 / テレオシジン / PAF antagonist / 保護基 / 喘息 / ビタミンB-12 / Platelet-Activating Factor / 複合系 / 2ー5A類 / 活性ビタミンD3 / proliferation / 分子機構 / 抗PAF剤 / 分化誘導物質 / retinoic acid / 反応設計 / PAF拮抗物質 / PAF antibodies / 反応制御 / 活性ビタミンD_3 / 立体選択的合成 / γ-グルタミルタウリン / 生体応答分子 / 抗PAF抗体 / オリゴマクレオチド / PAF antagonists / ペプチド縮合反応 / 5ーアミノレブリン酸 / ホスホリパーゼD / ペシロトキシン / ビタミンA / レチノイド / アセチルトランスフェラ-ゼ / ベプチド縮合反応 / 1,3ーポリオール / アミノ酸 / ホスホリパ-ゼ / phorbol / グラハミマイシンA_1 / 糖質化合物 / 肥満細胞 / ノ-アルケニルーGPE / Oーシリルケテンアセタール / PAFアンダゴニスト / teleocidin / 分化 / 核内レセプター / ビタミンA酸 / リゾPAF / 増殖 / 芳香族アミド / PAF antibody / ロイシン脱水素酵素 / 複合系の構造化学的アプロ-チ / 生物活性物質 / 好酸球 / ペプチド合成 / mast cells / リン脂質 / エステラーゼ / cーcmyc / active vitamin D / アラニン脱水素酵素 / PAF metabolizing enzymes / フォルボ-ル / Radioimmunoassay / レチノイン酸 / 血小板活性化因子(PAF) / ペプチド / platelet-activating factor / 血球分化
Less
Research Projects
(
20
results)
Co-Researchers
(
41
People)
Project Start Year(Newest)
Project Start Year(Oldest)
有機化学における複合系の高次制御
Principal Investigator
向山 光昭
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Science
Healing of several PAF-derived diseases by newly disigned PAF antagonists
Principal Investigator
WAKU Keizo
Project Period (FY)
1990 – 1991
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Faculty of Pharmaceutical Sciences, Teikyo University
微生物酵素による新しい物質交換系の開発
Principal Investigator
山田 秀明
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
複合系の分子機能
Principal Investigator
Principal Investigator
大野 雅二
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
有機化学における複合系の高次制御
Principal Investigator
向山 光昭
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Tokyo University of Science
複合系の分子機能
Principal Investigator
Principal Investigator
大野 雅二
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
The University of Tokyo
Catalytic Enantioselective Reaction
Principal Investigator
Principal Investigator
KOBAYASHI Susumu
, 大野 雅二
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Chemical pharmacy
Research Institution
University of Tokyo
新規生物活性物質創製の基礎研究
Principal Investigator
KOGA Kenji
Project Period (FY)
1988
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Field
Chemical pharmacy
Research Institution
The University of Tokyo
有機複合系研究の新手法
Principal Investigator
向山 光昭
Project Period (FY)
1988
Research Category
Grant-in-Aid for Co-operative Research (B)
Research Institution
Tokyo University of Science
微生物酵素による新しい物質変換系の開発
Principal Investigator
山田 秀明
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
Development of new drugs affecting PAF action by interacting to receptors and metabolizing enzymes.
Principal Investigator
NOJIMA Shoshichi
Project Period (FY)
1988 – 1989
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Biological pharmacy
Research Institution
Faculty of Pharmaceutical Sciences, Teikyo University
生物活性物質の化学変換
Principal Investigator
向山 光昭
Project Period (FY)
1987
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Tokyo University of Science
微生物酵素による新しい物質変換系の開発
Principal Investigator
山田 秀明
Project Period (FY)
1987
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyoto University
Chemical studies on specific regulatory molecules of cell proliferation and differentiation.
Principal Investigator
SHUDO Koichi
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Chemical pharmacy
Research Institution
The University of Tokyo
抗腫瘍性マクロリドRhizoxinの構造活性相関研究
Principal Investigator
Principal Investigator
大野 雅二
Project Period (FY)
1986
Research Category
Grant-in-Aid for Cancer Research
Research Institution
The University of Tokyo
生物活性物質の化学変換
Principal Investigator
向山 光昭
Project Period (FY)
1986
Research Category
Grant-in-Aid for Special Project Research
Research Institution
The University of Tokyo
生物活性物質の化学変換
Principal Investigator
向山 光昭
Project Period (FY)
1986 – 1988
Research Category
Grant-in-Aid for Special Project Research
Research Institution
Tokyo University of Science
Life Function and the Most Advanced Organic Chemistry
Principal Investigator
Principal Investigator
OHNO Masaji
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Chemical pharmacy
Research Institution
University of Tokyo
Construction of Novel Agents having Anti-hypertensive, Nticoaqula- Factors
Principal Investigator
Principal Investigator
OHNO Masaji
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
Biological pharmacy
Research Institution
Faculty of Pharmaceutical Sciences, University of Tokyo
The Enantioselective Synthesis of Some Useful Antibiotics based on the Chemicoenzymatic Strategy.
Principal Investigator
Principal Investigator
OHNO Masaji
Project Period (FY)
1984 – 1986
Research Category
Grant-in-Aid for General Scientific Research (A)
Research Field
Chemical pharmacy
Research Institution
Faculty of Pharmaceutical Sciences, University of Tokyo
# of Projects (Dsc)
# of Projects (Asc)
1.
向山 光昭
(60016003)
# of Collaborated Projects :
6results
# of Collaborated Products :
0results
2.
NOJIMA Shosichi
(70090470)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
3.
奈良坂 紘一
(50016151)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
4.
KOGA Kenji
(10012600)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
5.
KOBAYASHI Susumu
(70101102)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
6.
WAKU Keizo
(90013854)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
7.
INOUE Keizo
(30072937)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
8.
山田 秀明
(30027180)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
9.
清水 祥一
(00025842)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
10.
谷沢 和隆
(90001049)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
11.
永井 史郎
(70013307)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
12.
林 力丸
(90027186)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
13.
植木 正彬
(30084304)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
14.
桑嶋 功
(50016086)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
15.
光延 旺洋
(90082792)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
16.
野依 良治
(50022554)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
17.
田村 恭光
(40028824)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
18.
大石 武
(30001035)
# of Collaborated Projects :
3results
# of Collaborated Products :
0results
19.
桜井 英樹
(70025873)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
20.
KANEKO Chikara
(40013833)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
21.
杉浦 幸雄
(40025698)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
22.
大沢 利昭
(40012603)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
23.
板井 昭子
(60012647)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
24.
伊藤 嘉彦
(40026018)
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
25.
HIRAOKA Tetsuo
# of Collaborated Projects :
2results
# of Collaborated Products :
0results
26.
KANEMATSU Ken
(70023041)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
27.
KITAGAWA Isao
(20028830)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
28.
YAJIMA Haruaki
(00025678)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
29.
SHIGENORU Koki
(50012654)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
30.
SHUDO Koichi
(50012612)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
31.
ENDO Yasuyuki
(80126002)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
32.
IITAKA Yoichi
(90012591)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
33.
SANKAWA Ushio
(60012613)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
34.
岡崎 廉治
(70011567)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
35.
日野 亨
(10009160)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
36.
荒田 洋治
(40011499)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
37.
森 謙治
(20011843)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
38.
大和田 智彦
(20177025)
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
39.
中田 雅久
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
40.
森 弘
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
41.
MORI Hiroshi
# of Collaborated Projects :
1results
# of Collaborated Products :
0results
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