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OHNO Masaji  大野 雅二

ORCIDConnect your ORCID iD *help
Researcher Number 00111550
Affiliation (based on the past Project Information) *help 1986 – 1990: 東京大学, 薬学部, 教授
1986: Faculty of Pharmaceutical Sciences, Univ. of Tokyo, Professor, 薬学部, 教授
1985: 東京大学, 薬, 教授
Review Section/Research Field
Principal Investigator
Chemical pharmacy / Biological pharmacy
Except Principal Investigator
Chemical pharmacy / Biological pharmacy
Keywords
Principal Investigator
ブレオマイシン / 酸素活性化 / DNA切断 / コレシストキニン / 不斉反応 / Pig liver esterase / エスペラミシン / T細胞 / シアロシルグリセロリピド / ジメチルホスフィニル基 … More / 癌細胞障害性マクロファ-ジ / レクチン / 0ージメチルホスフィニル基 / Rhizoxin / Pig live esterase / cyclic hydroboration / Glutaric acid / L-tartaric acid / (S)-β-hydroxy isobutyric acid / Macloride(16員環) / 触媒的不斉合成 / アルキル化反応 / スルホンアミド / ジアルキル亜鉛 / シクロプロパン化反応 / キラルルイス酸 / 触媒的不斉反応 / ジエチル亜鉛 / ジヨ-ドメタン / アリルアルコ-ル / 触媒反応 / 不斉アルキル化 / 不斉シクロプロパン化 / カルベノイド / 不斉アルキル化反応 / オルトチタネ-ト / catalytic reaction / enantioselective reaction / alkylation / sulfonamide / dialkylzinc / cyclopropanation / chiral Lewis acid / 抗生物質の合成 / symmetrization-asymmetrization concept / retrosynthesis / ホーチミシン / リゾチシン / 豚肝臓エステラーゼ / 4-シクロヘキセン-1 / 2-シス-ジカルボン酸メチルエステル / カルバペネム / ミルベマイシン / アバメクチン / リゾキシン / Synthesis of antibiotics / Symmetrization-asymmetrization concept / Retrosynthesis / Fortimicine / 生命機能 / 精密有機化学 / ヌクレオシド / ビタミンD / 不斉合成 / ペプチド合成 / 酵素 / 精密有機合成 / β-ラクタム抗生物質 / Life function / Advanced organic chemistry / Nucleoside / Vitamine D / Asymmetric synthesis / Peptide ynthesis / 血小板活性化因子 / 1S-メチルPAF / Phospholipass A_2 / Conformational Drug design / 血圧降下剤 / 抗血栓剤 / 抗炎症剤 / PAF抗体 / phospholipase 【A_2】 / L-酒石酸 / Platelet Activating Factor / 1(S)-Me-PAF / Phospholipase A_2 / Drug Design / Anti- hypertensive / Anti-coagulative / Anti-inflammative … More
Except Principal Investigator
酵素的合成 / リパーゼ / トリチル塩 / セリン / 複合系高次制御 / 複合系の分子機能 / 複合系の反応試剤 / 複合系の反応設計 / 複合系の反応制御 / 有機合成化学 / 高選択的反応 / ケテンシリルアセタール / 人工ブレオマイシン / ポリオール類 / 微生物酵素 / PAF抗体 / 血小板活性化因子 / ラジオイムノアッセイ / PAF / 耐熱性フェニルアラニン脱水素酵素 / ペプチド合成 / リン脂質 / 5ーアミノレブリン酸 / エステラーゼ / 複合系の構造化学的アプローチ / 複合系の反応論的アプローチ / 複合系の構造化学的アプロ-チ / 複合系の反応論的アプロ-チ / オリゴマクレオチド / 保護基 / 糖質化合物 / 分岐型2-5A / シスタチオニン / アラニン脱水素酵素 / ベプチド縮合反応 / アミノ酸 / ビタミンB-12 / ペシロトキシン / 1,3ーポリオール / ブレオマイシン / Oーシリルケテンアセタール / 2ー5A類 / 5配位シリコナート / グラハミマイシンA_1 / アプリシアトキシン / 生物活性物質 / 生体応答分子 / 立体選択的合成 / 分子機構 / 天然物 / 複合系 / 複合系の高次制御 / 反応制御 / 反応設計 / ロイシン脱水素酵素 / ペプチド縮合反応 / ホスホリパーゼD / γ-グルタミルタウリン / 血小板活性化因子(PAF) / PAF受容体 / PAF拮抗物質 / 白血球 / 好酸球 / 肥満細胞 / 喘息 / アセチルトランスフェラ-ゼ / PAFアンダゴニスト / ホスホリパ-ゼ / リゾPAF / ノ-アルケニルーGPE / platelet-activating factor / PAF receptor / PAF antagonist / leukocytes / eosinophils / asthma / mast cells / PAF antibody / 分化 / 増殖 / ビタミンA / レチノイド / レチノイン酸 / テレオシジン / フォルボ-ル / 活性ビタミンD_3 / 活性ビタミンD3 / ビタミンA酸 / レセプター / 構造活性相関 / 核内レセプター / 分化誘導物質 / 血球分化 / 芳香族アミド / アフィディコリン / サイトカイニン / ペプチド / cーcmyc / retinoid, differentiation, vitamin A, retinoic acid. teleocidin retinoid / differentiation / vitamin A / teleocidin / retinoic acid / active vitamin D / phorbol / proliferation / PAFアンタゴニスト / 抗PAF剤 / PAF代謝酵素 / RIA / PAF分解酵素 / 抗PAF抗体 / Platelet-Activating Factor / PAF antibodies / Radioimmunoassay / PAF antagonists / Anti-PAF drugs / PAF metabolizing enzymes Less
  • Research Projects

    (20 results)
  • Co-Researchers

    (41 People)
  •  有機化学における複合系の高次制御

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  Healing of several PAF-derived diseases by newly disigned PAF antagonists

    • Principal Investigator
      WAKU Keizo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, Teikyo University
  •  微生物酵素による新しい物質交換系の開発

    • Principal Investigator
      山田 秀明
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  複合系の分子機能Principal Investigator

    • Principal Investigator
      大野 雅二
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  有機化学における複合系の高次制御

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Science
  •  複合系の分子機能Principal Investigator

    • Principal Investigator
      大野 雅二
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Catalytic Enantioselective ReactionPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Susumu, 大野 雅二
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      University of Tokyo
  •  新規生物活性物質創製の基礎研究

    • Principal Investigator
      KOGA Kenji
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The University of Tokyo
  •  有機複合系研究の新手法

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Tokyo University of Science
  •  微生物酵素による新しい物質変換系の開発

    • Principal Investigator
      山田 秀明
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Development of new drugs affecting PAF action by interacting to receptors and metabolizing enzymes.

    • Principal Investigator
      NOJIMA Shoshichi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, Teikyo University
  •  生物活性物質の化学変換

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Tokyo University of Science
  •  微生物酵素による新しい物質変換系の開発

    • Principal Investigator
      山田 秀明
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Chemical studies on specific regulatory molecules of cell proliferation and differentiation.

    • Principal Investigator
      SHUDO Koichi
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      The University of Tokyo
  •  抗腫瘍性マクロリドRhizoxinの構造活性相関研究Principal Investigator

    • Principal Investigator
      大野 雅二
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  生物活性物質の化学変換

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  生物活性物質の化学変換

    • Principal Investigator
      向山 光昭
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Tokyo University of Science
  •  Life Function and the Most Advanced Organic ChemistryPrincipal Investigator

    • Principal Investigator
      OHNO Masaji
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      University of Tokyo
  •  Construction of Novel Agents having Anti-hypertensive, Nticoaqula- FactorsPrincipal Investigator

    • Principal Investigator
      OHNO Masaji
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, University of Tokyo
  •  The Enantioselective Synthesis of Some Useful Antibiotics based on the Chemicoenzymatic Strategy.Principal Investigator

    • Principal Investigator
      OHNO Masaji
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Faculty of Pharmaceutical Sciences, University of Tokyo
  • 1.  向山 光昭 (60016003)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  NOJIMA Shosichi (70090470)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  奈良坂 紘一 (50016151)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KOGA Kenji (10012600)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KOBAYASHI Susumu (70101102)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  WAKU Keizo (90013854)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  INOUE Keizo (30072937)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  山田 秀明 (30027180)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  清水 祥一 (00025842)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  谷沢 和隆 (90001049)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  永井 史郎 (70013307)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  林 力丸 (90027186)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  植木 正彬 (30084304)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  桑嶋 功 (50016086)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  光延 旺洋 (90082792)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  野依 良治 (50022554)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  田村 恭光 (40028824)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  大石 武 (30001035)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  桜井 英樹 (70025873)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  KANEKO Chikara (40013833)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  杉浦 幸雄 (40025698)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  大沢 利昭 (40012603)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  板井 昭子 (60012647)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  伊藤 嘉彦 (40026018)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  HIRAOKA Tetsuo
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  KANEMATSU Ken (70023041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KITAGAWA Isao (20028830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  YAJIMA Haruaki (00025678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  SHIGENORU Koki (50012654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SHUDO Koichi (50012612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ENDO Yasuyuki (80126002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  IITAKA Yoichi (90012591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  SANKAWA Ushio (60012613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  岡崎 廉治 (70011567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  日野 亨 (10009160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  荒田 洋治 (40011499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  森 謙治 (20011843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  大和田 智彦 (20177025)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  中田 雅久
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  森 弘
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  MORI Hiroshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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