HAMAJIMA Kenji 浜島健治

Researcher Number	00114611
Other IDs
Affiliation *help	1996 – 2004 : YOKOHAMA CITY UNIVERSITY,SCHOOL OF MEDICINE,RESEARCH ASSISTANT, 医学部, 助手 1994 : 横浜市立大学, 医学部, 助手 1992 : 横浜市立大学, 医学部, 助手 1987 : Dept. of Bacteriol., Yokohama City Univ., School of Med., Assistant, 医学部・細菌学講座, 助手 1986 : 横浜市立大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / Immunology / Neurophysiology and muscle physiology
Keywords	Principal Investigator CTL / 活性化T細胞 / CpG motif / 経膣 / 組換ウイルスベクター / 経皮 / 経直腸 / 組み換えアデノウイルス / DNA vaccine / 活性化Tリンパ球 … More Except Principal Investigator HIV-1 / DNAワクチン / HIV / 緑膿菌 / IL-12 / influenza virus / エラスターゼ / インフルエンザウイルス / DNA vaccine / 鞭毛抗原 / 緑膿菌病原因子 / Gag / LasR / 転写制御 / Nef / インフルエンザ / Env / 線毛抗原 / アルカリプロテアーゼ / AIDS / Fur / 新世代DNAワクチン / タンパク質の分泌 / ウイルスベクター / Pseudomonas aeruginosa / Pol / 粘膜免疫 / gag-pol / サザーンハイブリダイゼーション / 組み換えDNA / IL-2 / 細胞性免疫 / 遺伝子発現 / DNA immunization method / protective immunity / 35 virus / 哺乳動物の脳 / V3ペプチド / Transfection / mucosal immunity / 遅延型過敏症反応 / El deficient adeno virus / DNA VACCINE / サイトカインアジュバント / 感染モデル / CMV promoter / サイトカイン発現プラスミド / IFN-γ / Nef. / 細胞障害性T細胞 / gp160 / ペプチド / E1欠損型アデノウイルス / 感染予防 / gP160 / 粘膜免疫反応 / epitope / Insituハイブリダイゼーション / gp120 / cytokine expression plasmid / Th1細胞 / 細胞障害性T細胞(CTLs) / Pseudomonas / CpG motif / 脳特異的発現 / pseudomonas / Immunogenetics / vaccine / T helper cell type 1 / SIV chimera virus / vaccine for the next generation / ヒト化コドン / 抗原決定基 / DNA免疫法 / Brain specific expression / CpGモチーフ / 分子生物学 / 非放射性DNA標識 / Gene expression / 緑能菌 / cytotoxic T lymphocyte / アデノ5 / flagellar antigen / IL-2発現プラスミド / GM-CSFプラスミド / 緑膿菌ワクチン / delayed type hypersensitivity / 細胞障害製T細胞(CTL) / ヒト型コドン / pilli antigen / 抗原提示作用 / Non-radioactive DNA labeling / Northern Hybridization / F35ウイルス / ウエスターンハイブリダイゼーション / アジュバント / アデノ随伴ウイルス / 脳のアルギニノコハク酸リアーゼcDNA / crytotoxic T lymphocyte / HIV clade C / Th1 / Virus vector / サイトカイン / エピトープ / 感染防御抗原 / IL-I2 / 感染防御 / エクソトキシンA / cellular immunity / 組換えワクチン / humanized codon / In situ hybridization / サイトカインプラスミド / Transgenic mouse / Mammalian Brain / adeno 5 / CTLエピトープ / SCIDマウス / HIV-1C型 / ノーザーンハイブリダイゼーション Less

Developmental research of new generation DNA vaccine against microorganism using synthesized DNA
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  YOKOHAMA CITY UNIVERSITY
The adjuvant effects of CpG motif and activated large number of activated-T lymphocytes on immunoresponses.Principal Investigator
- Principal Investigator
  
  HAMAJIMA Kenji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Enhancement of protection against various microbial infection by the modification of dominance of Thl or Th2 immune responses
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Study on the DNA immunization against microbial infection
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C).
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Enhancement of cellular immunity and protection against pseudomonas aeruginosa infection by CpG DNA motif and cytokine
- Principal Investigator
  
  FUKUSHIMA Jun
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  AKITA PREFRCTYRAL UNIVERSITY
  Yokohama City University
Roles of activation of antigen specific cytoxic T cells against micro bial infections.
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Th1細胞活性化による細胞内寄生体に対する感染防御の検討
- Principal Investigator
  
  奥田研爾
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
THE POSSIBILITY OF DNA VACCINE DEVELOPMENT AGAINST HIV-1
- Principal Investigator
  
  FUKUSHIMA Jun
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  YOKOHAMA CITY UNIVERSITY SCHOOL OF MEDICINE
緑濃菌の病原因子エラスターゼとアルカリプロテアーゼの構造と発現制御に関する研究
- Principal Investigator
  
  奥田研爾
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
エイズワクチン開発の基礎的研究
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
緑膿菌の産生する病原性因子エラスターゼ,アルカリプロテアーゼの分子生物学的研究
- Principal Investigator
  
  奥田研爾
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Institution
  Yokohama City University
主要組織適合抗原(主にクラスII抗原)遺伝子の分子遺伝学的研究
- Principal Investigator
  
  奥田研爾
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Yokohama City University
Genetic Analysis of specific expressions in mammalian brains.
- Principal Investigator
  
  TAKAHASHI Toyozoh
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yokohama City University School of Medicine

All 2003

All Journal Article

[Journal Article] Contribution of the rev gene to the immunogenicity of DNA vaccines targetting the envelope glycoprotein of HIV2003
- Author(s)
  Jounai, N., Okuda, K., Kojima, Y., Toda, Y., Hamajima, K., Ohba, K., Klinman, D., Xin, K.-Q.
- Journal Title
  
  J Gene Med 5
  
  Pages : 609-617
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Chitin micro-particles (CMP) is a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine2003
- Author(s)
  Hamajima, K., Kojima, Y., Matsui, K., Toda, Y., Jounai, N., Ozaki, T., Xin, K.-Q., Strong, P., Okuda, K.
- Journal Title
  
  Viral Immunol 16
  
  Pages : 541-547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Chitin micro-paricles(CMP) : a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine.2003
- Author(s)
  Hamajima K et al.
- Journal Title
  
  Viral Immunol 16・4
  
  Pages : 541-547
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] A DNA vaccine containing inverted terminal repeats from adeno-associated virus increases immunity to HIV2003
- Author(s)
  Xin, K.-Q., Ooki, T., Jounai, N., Mizukami, H., Hamajima, K., Kojima, Y., Ohba, K., Toda, Y,.Hirai, S., Klinman, D.M., Ozawa, K., Okuda, K.
- Journal Title
  
  J Gene Med 5
  
  Pages : 438-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145
[Journal Article] Immunogenicity and protective efficacy of orally administered recombinant Lactococcus lactis expressing surface-bound HIV Env2003
- Author(s)
  Xin, K.-Q., Hoshino, Y., Toda, Y., Igimi, S., Kojima, Y., Jounai, N., Ohba, K., Kushiro, A., Kiwaki, M., Hamajima, K., Klinman, D., Okuda, K.
- Journal Title
  
  Blood 102
  
  Pages : 223-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390145

1. OKUDA Kenji (40124862)

# of Collaborated Projects : 10results

# of Collaborated Products : 4results
2. FUKUSHIMA Jun (00181256)

# of Collaborated Projects : 9results

# of Collaborated Products : 0results
3. XIN Ke Qin (40301452)

# of Collaborated Projects : 3results

# of Collaborated Products : 4results
4. AOKI Ichirou (00184028)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
5. 川本進 (80125921)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. TAKAHASHI Toyozoh (40046149)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. KUDOH Ichidai (30145700)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. CULLEN B.R.

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. CULLEN Bryanr

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. PHANUPHAK Pr

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. HINKULA Jorm

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. WAHREN Britt

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

HAMAJIMA Kenji 浜島 健治

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The adjuvant effects of CpG motif and activated large number of activated-T lymphocytes on immunoresponses.Principal Investigator

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[Journal Article] Contribution of the rev gene to the immunogenicity of DNA vaccines targetting the envelope glycoprotein of HIV2003

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[Journal Article] Chitin micro-particles (CMP) is a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine2003

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[Journal Article] Chitin micro-paricles(CMP) : a useful adjuvant for inducing viral specific immunity when delivered intranasally with an HIV-DNA vaccine.2003

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HAMAJIMA Kenji 浜島健治